Piper latifolium
Piper latifolium · Accepted scientific name
Scientific literature: Very Extensive (486 studies) · ★★★★★
, scientifically known as Piper latifolium, is a versatile medicinal plant belonging to the Piperaceae family. Renowned for its potent therapeutic properties, it is widely used in traditional medicine to treat various ailments. This plant contains bioactive compounds that offer significant antioxidant, antimicrobial, and anti-inflammatory benefits for holistic wellness.
- Family
- Not available
- Native range
- Pacific
- Parts used
- Root · Rhizome
- Common names
- Not available
- Scientific synonyms
- Not available
Names and Synonyms
Scientific Names
Accepted name
Piper latifoliumDistribution
This plant exhibits a wide distribution across several key regions of the Pacific Ocean. In the Southwestern Pacific, its presence is documented on the Santa Cruz Islands and throughout Vanuatu. Moving into the South-Central Pacific, the species can also be found within the Cook Islands. Furthermore, its range extends to the Marquesas Islands in the same central region. Finally, the plant is known to inhabit the Society Islands, completing its broad geographical spread.
| Region | Area |
|---|---|
| Southwestern Pacific | Santa Cruz Is. |
| Southwestern Pacific | Vanuatu |
| South-Central Pacific | Cook Is. |
| South-Central Pacific | Marquesas |
| South-Central Pacific | Society Is. |
| South-Central Pacific | Tubuai Is. |
| Northwestern Pacific | Caroline Is. |
| North-Central Pacific | Hawaii |
Sources: The World Checklist of Vascular Plants (WCVP)
Plant Parts
Piper latifolium has 2 reported plant parts identified across 11 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, rhizome.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 7 supporting sources | ★★★★☆ |
| Rhizome | 4 supporting sources | ★★☆☆☆ |
Root
- Biomedical & environmental mass spectrometry
- Planta medica
- Oxidative medicine and cellular longevity
- Molecules (Basel, Switzerland)
- Journal of the American Academy of Dermatology
View 2 additional sources
- Nutrients
- Phytochemistry
Rhizome
- Planta medica
- Psychopharmacology
- Chemico-biological interactions
- Annals of hepatology
Chemicals
Piper latifolium has 108 reported phytochemicals identified across 11 scientific publications and several other databases. The most consistently reported chemicals include Methysticin, Yangonin, Dihydromethysticin, Desmethoxyyangonin, kavain.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Methysticin | 13 supporting sources | ★★★★★ |
| Yangonin | 12 supporting sources | ★★★★★ |
| Dihydromethysticin | 10 supporting sources | ★★★★★ |
| Desmethoxyyangonin | 9 supporting sources | ★★★★☆ |
| kavain | 9 supporting sources | ★★★★☆ |
| Dihydrokavain | 6 supporting sources | ★★★☆☆ |
| Dihydrokawain | 5 supporting sources | ★★★☆☆ |
| Kawain | 5 supporting sources | ★★★☆☆ |
| Kava | 3 supporting sources | ★★☆☆☆ |
| Kavapyrone | 3 supporting sources | ★★☆☆☆ |
Methysticin
- Dr. Duke
- Planta medica
- Drug metabolism and disposition: the biological fate of chemicals
- Progress in neuro-psychopharmacology & biological psychiatry
- Molecules (Basel, Switzerland)
View 8 additional sources
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- European journal of pharmacology
- Clinical and experimental pharmacology & physiology
- Chemico-biological interactions
- Psychopharmacology
- Journal of ethnopharmacology
- PloS one
- European journal of mass spectrometry (Chichester, England)
Yangonin
- Dr. Duke
- Planta medica
- Progress in neuro-psychopharmacology & biological psychiatry
- Journal of pharmaceutical sciences
- European journal of pharmacology
View 7 additional sources
- Pharmacopsychiatry
- Psychopharmacology
- Journal of chromatography
- Chemico-biological interactions
- Journal of ethnopharmacology
- PloS one
- European journal of mass spectrometry (Chichester, England)
Dihydromethysticin
- Dr. Duke
- Progress in neuro-psychopharmacology & biological psychiatry
- Planta medica
- Molecules (Basel, Switzerland)
- European journal of pharmacology
View 5 additional sources
- Clinical and experimental pharmacology & physiology
- Chemico-biological interactions
- Psychopharmacology
- Journal of ethnopharmacology
- European journal of mass spectrometry (Chichester, England)
Desmethoxyyangonin
- Dr. Duke
- Progress in neuro-psychopharmacology & biological psychiatry
- Planta medica
- Journal of pharmaceutical sciences
- Pharmacopsychiatry
View 4 additional sources
- Psychopharmacology
- Chemico-biological interactions
- Journal of ethnopharmacology
- European journal of mass spectrometry (Chichester, England)
kavain
- Planta medica
- Molecules (Basel, Switzerland)
- Natural product research
- Psychopharmacology
- Journal of ethnopharmacology
View 4 additional sources
- Journal of separation science
- Chemico-biological interactions
- European journal of mass spectrometry (Chichester, England)
- Journal of clinical psychopharmacology
Dihydrokavain
- Planta medica
- Psychopharmacology
- Journal of separation science
- Chemico-biological interactions
- Journal of ethnopharmacology
View 1 additional sources
- European journal of mass spectrometry (Chichester, England)
Dihydrokawain
- Dr. Duke
- Progress in neuro-psychopharmacology & biological psychiatry
- Journal of pharmaceutical sciences
- European journal of pharmacology
- Clinical and experimental pharmacology & physiology
Kawain
- Dr. Duke
- Journal of pharmaceutical sciences
- European journal of pharmacology
- Clinical and experimental pharmacology & physiology
- PloS one
Kava
- Drug metabolism reviews
- Canadian journal of psychiatry. Revue canadienne de psychiatrie
- Deutsche medizinische Wochenschrift (1946)
Kavapyrone
- Zeitschrift fur Gastroenterologie
- Die Naturwissenschaften
- Alternative medicine review : a journal of clinical therapeutic
Activities
Piper latifolium has 163 reported activities identified across 11 scientific publications and several other databases. The most consistently reported activities include Anxiolytic, Sedative, Psychoactive, Analgesic, Anesthetic.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Anxiolytic | 16 supporting sources | ★★★★★ |
| Sedative | 6 supporting sources | ★★★☆☆ |
| Psychoactive | 5 supporting sources | ★★★☆☆ |
| Analgesic | 4 supporting sources | ★★☆☆☆ |
| Anesthetic | 3 supporting sources | ★★☆☆☆ |
| Hepatotoxic | 3 supporting sources | ★★☆☆☆ |
| Anticancer | 2 supporting sources | ★☆☆☆☆ |
| Antidepressant | 2 supporting sources | ★☆☆☆☆ |
| Antinociceptive | 2 supporting sources | ★☆☆☆☆ |
| Antioxidant | 2 supporting sources | ★☆☆☆☆ |
Anxiolytic
- Dr. Duke
- British journal of clinical pharmacology
- Substance abuse treatment, prevention, and policy
- The Australian and New Zealand journal of psychiatry
- Human psychopharmacology
View 11 additional sources
- Drug safety
- Planta medica
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Pharmacological research
- Alternative medicine review : a journal of clinical therapeutic
- Psychopharmacology
- Journal of traditional and complementary medicine
- Journal of ethnopharmacology
- Chemico-biological interactions
- Annals of hepatology
- Trials
Sedative
- Dr. Duke
- Journal of clinical pharmacy and therapeutics
- Journal of psychosocial nursing and mental health services
- Complementary therapies in medicine
- Chemico-biological interactions
View 1 additional sources
- Neurotoxicology and teratology
Psychoactive
- Dr. Duke
- Journal of pharmaceutical sciences
- Pharmacopsychiatry
- The American Journal of dermatopathology
- Hawaii medical journal
Analgesic
- Dr. Duke
- Alternative medicine review : a journal of clinical therapeutic
- Clinical and experimental pharmacology & physiology
- Neurotoxicology and teratology
Anesthetic
- Dr. Duke
- Alternative medicine review : a journal of clinical therapeutic
- Journal of psychosocial nursing and mental health services
Hepatotoxic
- Journal of clinical pharmacy and therapeutics
- Annals of hepatology
- The American journal of drug and alcohol abuse
Anticancer
- Evidence-based complementary and alternative medicine : eCAM
- Nutrients
Antidepressant
- Deutsche medizinische Wochenschrift (1946)
- Pharmacoepidemiology and drug safety
Antinociceptive
- Dr. Duke
- Natural product research
Antioxidant
- Dr. Duke
- Oxidative medicine and cellular longevity
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| beverages | Planta medica (and other 2 sources) | ★☆☆☆☆ |
| (+) -kavain | Planta medica (and other 1 sources) | ★☆☆☆☆ |
| Kava beverages | Nutrients (and other 1 sources) | ★☆☆☆☆ |
| Kava extract | Journal of traditional and complementary medicine (and other 1 sources) | ★☆☆☆☆ |
| Kava extract preparations | Nutrients (and other 1 sources) | ★☆☆☆☆ |
| Kavapyrones | Psychopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Kavapyrones enriched extract | Psychopharmacology (and other 1 sources) | ★☆☆☆☆ |
| aqueous acid extraction | Biomedical & environmental mass spectrometry (and other 1 sources) | ★☆☆☆☆ |
| aqueous extraction | Journal of chromatography (and other 1 sources) | ★☆☆☆☆ |
| aqueous extracts | Annals of hepatology (and other 1 sources) | ★☆☆☆☆ |