Piper latifolium

Piper latifolium · Accepted scientific name

Scientific literature: Very Extensive (486 studies) · ★★★★★

, scientifically known as Piper latifolium, is a versatile medicinal plant belonging to the Piperaceae family. Renowned for its potent therapeutic properties, it is widely used in traditional medicine to treat various ailments. This plant contains bioactive compounds that offer significant antioxidant, antimicrobial, and anti-inflammatory benefits for holistic wellness.

Family
Not available
Native range
Pacific
Parts used
Root · Rhizome
Common names
Not available
Scientific synonyms
Not available

Names and Synonyms

Scientific Names

Accepted name

Piper latifolium

Distribution

This plant exhibits a wide distribution across several key regions of the Pacific Ocean. In the Southwestern Pacific, its presence is documented on the Santa Cruz Islands and throughout Vanuatu. Moving into the South-Central Pacific, the species can also be found within the Cook Islands. Furthermore, its range extends to the Marquesas Islands in the same central region. Finally, the plant is known to inhabit the Society Islands, completing its broad geographical spread.

Region Area
Southwestern Pacific Santa Cruz Is.
Southwestern Pacific Vanuatu
South-Central Pacific Cook Is.
South-Central Pacific Marquesas
South-Central Pacific Society Is.
South-Central Pacific Tubuai Is.
Northwestern Pacific Caroline Is.
North-Central Pacific Hawaii

Sources: The World Checklist of Vascular Plants (WCVP)

Plant Parts

Piper latifolium has 2 reported plant parts identified across 11 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, rhizome.

Plant parts reported in Piper latifolium
Plant part Supporting sources Consensus
Root 7 supporting sources ★★★★☆
Rhizome 4 supporting sources ★★☆☆☆

Root

  1. Biomedical & environmental mass spectrometry
  2. Planta medica
  3. Oxidative medicine and cellular longevity
  4. Molecules (Basel, Switzerland)
  5. Journal of the American Academy of Dermatology
View 2 additional sources
  1. Nutrients
  2. Phytochemistry

Rhizome

  1. Planta medica
  2. Psychopharmacology
  3. Chemico-biological interactions
  4. Annals of hepatology

Chemicals

Piper latifolium has 108 reported phytochemicals identified across 11 scientific publications and several other databases. The most consistently reported chemicals include Methysticin, Yangonin, Dihydromethysticin, Desmethoxyyangonin, kavain.

Chemicals reported in Piper latifolium
Chemical Supporting sources Consensus
Methysticin 13 supporting sources ★★★★★
Yangonin 12 supporting sources ★★★★★
Dihydromethysticin 10 supporting sources ★★★★★
Desmethoxyyangonin 9 supporting sources ★★★★☆
kavain 9 supporting sources ★★★★☆
Dihydrokavain 6 supporting sources ★★★☆☆
Dihydrokawain 5 supporting sources ★★★☆☆
Kawain 5 supporting sources ★★★☆☆
Kava 3 supporting sources ★★☆☆☆
Kavapyrone 3 supporting sources ★★☆☆☆

Methysticin

  1. Dr. Duke
  2. Planta medica
  3. Drug metabolism and disposition: the biological fate of chemicals
  4. Progress in neuro-psychopharmacology & biological psychiatry
  5. Molecules (Basel, Switzerland)
View 8 additional sources
  1. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  2. European journal of pharmacology
  3. Clinical and experimental pharmacology & physiology
  4. Chemico-biological interactions
  5. Psychopharmacology
  6. Journal of ethnopharmacology
  7. PloS one
  8. European journal of mass spectrometry (Chichester, England)

Yangonin

  1. Dr. Duke
  2. Planta medica
  3. Progress in neuro-psychopharmacology & biological psychiatry
  4. Journal of pharmaceutical sciences
  5. European journal of pharmacology
View 7 additional sources
  1. Pharmacopsychiatry
  2. Psychopharmacology
  3. Journal of chromatography
  4. Chemico-biological interactions
  5. Journal of ethnopharmacology
  6. PloS one
  7. European journal of mass spectrometry (Chichester, England)

Dihydromethysticin

  1. Dr. Duke
  2. Progress in neuro-psychopharmacology & biological psychiatry
  3. Planta medica
  4. Molecules (Basel, Switzerland)
  5. European journal of pharmacology
View 5 additional sources
  1. Clinical and experimental pharmacology & physiology
  2. Chemico-biological interactions
  3. Psychopharmacology
  4. Journal of ethnopharmacology
  5. European journal of mass spectrometry (Chichester, England)

Desmethoxyyangonin

  1. Dr. Duke
  2. Progress in neuro-psychopharmacology & biological psychiatry
  3. Planta medica
  4. Journal of pharmaceutical sciences
  5. Pharmacopsychiatry
View 4 additional sources
  1. Psychopharmacology
  2. Chemico-biological interactions
  3. Journal of ethnopharmacology
  4. European journal of mass spectrometry (Chichester, England)

kavain

  1. Planta medica
  2. Molecules (Basel, Switzerland)
  3. Natural product research
  4. Psychopharmacology
  5. Journal of ethnopharmacology
View 4 additional sources
  1. Journal of separation science
  2. Chemico-biological interactions
  3. European journal of mass spectrometry (Chichester, England)
  4. Journal of clinical psychopharmacology

Dihydrokavain

  1. Planta medica
  2. Psychopharmacology
  3. Journal of separation science
  4. Chemico-biological interactions
  5. Journal of ethnopharmacology
View 1 additional sources
  1. European journal of mass spectrometry (Chichester, England)

Dihydrokawain

  1. Dr. Duke
  2. Progress in neuro-psychopharmacology & biological psychiatry
  3. Journal of pharmaceutical sciences
  4. European journal of pharmacology
  5. Clinical and experimental pharmacology & physiology

Kawain

  1. Dr. Duke
  2. Journal of pharmaceutical sciences
  3. European journal of pharmacology
  4. Clinical and experimental pharmacology & physiology
  5. PloS one

Kava

  1. Drug metabolism reviews
  2. Canadian journal of psychiatry. Revue canadienne de psychiatrie
  3. Deutsche medizinische Wochenschrift (1946)

Kavapyrone

  1. Zeitschrift fur Gastroenterologie
  2. Die Naturwissenschaften
  3. Alternative medicine review : a journal of clinical therapeutic

Activities

Piper latifolium has 163 reported activities identified across 11 scientific publications and several other databases. The most consistently reported activities include Anxiolytic, Sedative, Psychoactive, Analgesic, Anesthetic.

Activities reported in Piper latifolium
Activity Supporting sources Consensus
Anxiolytic 16 supporting sources ★★★★★
Sedative 6 supporting sources ★★★☆☆
Psychoactive 5 supporting sources ★★★☆☆
Analgesic 4 supporting sources ★★☆☆☆
Anesthetic 3 supporting sources ★★☆☆☆
Hepatotoxic 3 supporting sources ★★☆☆☆
Anticancer 2 supporting sources ★☆☆☆☆
Antidepressant 2 supporting sources ★☆☆☆☆
Antinociceptive 2 supporting sources ★☆☆☆☆
Antioxidant 2 supporting sources ★☆☆☆☆

Anxiolytic

  1. Dr. Duke
  2. British journal of clinical pharmacology
  3. Substance abuse treatment, prevention, and policy
  4. The Australian and New Zealand journal of psychiatry
  5. Human psychopharmacology
View 11 additional sources
  1. Drug safety
  2. Planta medica
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Pharmacological research
  5. Alternative medicine review : a journal of clinical therapeutic
  6. Psychopharmacology
  7. Journal of traditional and complementary medicine
  8. Journal of ethnopharmacology
  9. Chemico-biological interactions
  10. Annals of hepatology
  11. Trials

Sedative

  1. Dr. Duke
  2. Journal of clinical pharmacy and therapeutics
  3. Journal of psychosocial nursing and mental health services
  4. Complementary therapies in medicine
  5. Chemico-biological interactions
View 1 additional sources
  1. Neurotoxicology and teratology

Psychoactive

  1. Dr. Duke
  2. Journal of pharmaceutical sciences
  3. Pharmacopsychiatry
  4. The American Journal of dermatopathology
  5. Hawaii medical journal

Analgesic

  1. Dr. Duke
  2. Alternative medicine review : a journal of clinical therapeutic
  3. Clinical and experimental pharmacology & physiology
  4. Neurotoxicology and teratology

Anesthetic

  1. Dr. Duke
  2. Alternative medicine review : a journal of clinical therapeutic
  3. Journal of psychosocial nursing and mental health services

Hepatotoxic

  1. Journal of clinical pharmacy and therapeutics
  2. Annals of hepatology
  3. The American journal of drug and alcohol abuse

Anticancer

  1. Evidence-based complementary and alternative medicine : eCAM
  2. Nutrients

Antidepressant

  1. Deutsche medizinische Wochenschrift (1946)
  2. Pharmacoepidemiology and drug safety

Antinociceptive

  1. Dr. Duke
  2. Natural product research

Antioxidant

  1. Dr. Duke
  2. Oxidative medicine and cellular longevity

Preparations

Preparations Sources Consensus
beverages Planta medica (and other 2 sources) ★☆☆☆☆
(+) -kavain Planta medica (and other 1 sources) ★☆☆☆☆
Kava beverages Nutrients (and other 1 sources) ★☆☆☆☆
Kava extract Journal of traditional and complementary medicine (and other 1 sources) ★☆☆☆☆
Kava extract preparations Nutrients (and other 1 sources) ★☆☆☆☆
Kavapyrones Psychopharmacology (and other 1 sources) ★☆☆☆☆
Kavapyrones enriched extract Psychopharmacology (and other 1 sources) ★☆☆☆☆
aqueous acid extraction Biomedical & environmental mass spectrometry (and other 1 sources) ★☆☆☆☆
aqueous extraction Journal of chromatography (and other 1 sources) ★☆☆☆☆
aqueous extracts Annals of hepatology (and other 1 sources) ★☆☆☆☆