Picrasma chinensis

Picrasma chinensis · Accepted scientific name

Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆

Picrasma chinensis is a significant medicinal plant known for its potent bioactive properties. The primary components utilized from this species include the leaf and the stem. Researchers often focus on the EtOH extract to isolate its most effective chemical compounds. This specific preparation is frequently studied for its diverse pharmacological potential in various applications. Understanding the relationship between its botanical parts and chemical extracts remains vital for future studies.

Quick facts
Synonyms
Not available
Common names
Not available
Family
Simaroubaceae
Distribution
Not available
Plant Parts
Leaf · Stem

Classification

Common Names

Picrasma chinensis is a distinctive botanical species known by several descriptive names in its native regions. It is frequently referred to by the common name 中国苦木, reflecting its specific cultural and linguistic roots. Similarly, many people recognize the plant as 中国苦树, a variation that highlights its botanical identity. These overlapping names serve to connect the species to its traditional heritage and local usage. Understanding these various common titles helps enthusiasts and researchers identify the plant more easily across different contexts.

Sources: Catalogue of Life (COL)

Taxonomy

Picrasma chinensis is a fascinating botanical specimen that belongs to the kingdom Plantae. Within this vast biological realm, it is classified under the class Equisetopsida. This species is further organized into the order Sapindales, reflecting its specific evolutionary lineage. It is a prominent member of the genus Picrasma, which distinguishes its unique characteristics. Finally, this plant is nested within the Simaroubaceae family, completing its complex taxonomic profile.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Sapindales
Family Simaroubaceae
Genus Picrasma

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Picrasma chinensis exhibits a broad geographical range that spans across several distinct ecological zones. In the temperate regions of Asia, this species is widely distributed throughout China, including its South-Central and Southeast territories. Its presence also extends into the high-altitude landscapes of Tibet. Moving into more tropical climates, the plant can be found within the Indo-China region. Specifically, its reach encompasses the lush environments of Myanmar, demonstrating its adaptability to diverse habitats.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Morphology

Picrasma chinensis is a self-supporting tree characterized by its sturdy growth form. This species typically reaches a maximum height of 15 meters as it matures. Its structural integrity allows it to stand firmly within its natural habitat.

Sources: Global Inventory of Floras and Traits (GIFT)

Biological Activities

Compounds

Conditions

Picrasma chinensis contains bioactive compounds that effectively treat H2O2-damaged SH-SY5Y cells. These extracts demonstrate a significant neuroprotective effect against H2O2-induced damage on human neuroblastoma SH-SY5Y cells. Furthermore, the plant provides therapeutic benefits for the MPTP-damaged mouse brain by protecting dopaminergic neurons. Its derivatives specifically work to treat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease by restoring tyrosine hydroxylase expression. Ultimately, the medicinal properties of Picrasma chinensis allow it to treat MPTP-induced Parkinson's disease in animal models by improving motor behavioral performance.

Preparations

Picrasma chinensis is prepared as an EtOH extract to facilitate the isolation of its chemical constituents. From the ethanol extract of the plant's stems and leaves, researchers successfully isolated six novel cyclopeptide alkaloid-type burpitides known as picrachinentins A-F. This specific extraction method allowed for the full structural elucidation of these unique 14-membered paracyclophane ring systems. By using an EtOH extract, the study was able to identify these compounds as the first reported CPABs from the Simaroubaceae family. Consequently, this preparation method proved essential for uncovering the neuroprotective properties inherent in the plant's bioactive molecules.

Parts used

Picrasma chinensis serves as a significant source of bioactive compounds for pharmacological research. Scientific studies have successfully isolated various chemical constituents, such as sesquiterpenoids and cyclopeptide alkaloid-type burpitides, directly from the plant. These valuable metabolites are specifically extracted from both the leaves and the stems of the species. The compounds found in these plant parts have demonstrated remarkable neuroprotective effects in both in vitro and in vivo models. Consequently, the chemical diversity present in the stems and leaves of Picrasma chinensis holds great promise for developing treatments for neurodegenerative conditions.