Calabar bean

Physostigma venenosum · Accepted scientific name

Scientific literature: Moderate (120 studies) · ★★★☆☆

Calabar bean, scientifically known as Physostiema venenosa, is a potent tropical climbing plant renowned for its bioactive alkaloids. Primarily recognized for containing physostigmine, it has historically been used as a powerful purgative and muscle relaxant. Today, its chemical properties remain vital in pharmacological research and neurological studies.

Family
Fabaceae
Native range
Africa
Parts used
Not available
Common names
Calabar-Bean · Ordeal-Bean · 1 more
Scientific synonyms
Not available

Names and Synonyms

Common Names

Scientific Names

Accepted name

Physostigma venenosum

Regional and Traditional Names

Spanish:

  • Frijol de Calabar

German:

  • Kalabarbohne
  • Calabarbohne
  • Calabar-Bohne
  • Gottesurteilbohne
  • Calabarbohne

French:

  • Fève de Calabar
  • Fève de calabar
  • Fève De Calabar
  • Feve de Calabar
  • éseré
  • fève de Calabar

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and the class Equisetopsida. Under the subclass Magnoliidae, it falls into the order Fabales and the family Fabaceae. Finally, it is identified by the genus Physostigma.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Fabales
Family Fabaceae
Genus Physostigma

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, known as Physostigma venenosum, is found across several regions of West Tropical Africa. Its distribution specifically includes the nation of Ghana, where it grows in local ecosystems. It is also documented in Guinea, marking its presence in the coastal and inland areas of that country. Furthermore, the species can be located within the borders of the Ivory Coast and Liberia. Finally, the geographical range of this medicinal plant extends into Mali, completing its presence in the West Tropical African zone.

Region Area
West Tropical Africa Ghana
West Tropical Africa Guinea
West Tropical Africa Ivory Coast
West Tropical Africa Liberia
West Tropical Africa Mali
West Tropical Africa Nigeria
West Tropical Africa Sierra Leone
West-Central Tropical Africa Central African Republic
West-Central Tropical Africa Cameroon
West-Central Tropical Africa Congo

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Physostigma venenosum is characterized by its classification as a phanerophyte, specifically manifesting as a nanophanerophyte, where its perennating buds are located well above the soil surface. As a perennial climber, it maintains an evergreen deciduousness, ensuring that its foliage remains functional throughout its growth cycles rather than shedding seasonally. This life form strategy, functioning primarily as a phanerophyte, allows the plant to establish a robust presence in its habitat by protecting its vital reproductive and vegetative buds above the ground level.

Deciduousness :
evergreen
Life form :
phanerophyte

Morphology

The morphology of Physostigma venenosum is characterized by its significant stature, with a mean plant height reaching approximately 10 m. It functions as an obligatory climber, specifically categorized as a liana, which allows it to ascend through surrounding vegetation. While its growth form is described as shrub-like in certain contexts, its structural development is primarily that of a woody liana. This plant is strictly terrestrial in its habit, rather than epiphytic, establishing its root system in the soil to support its climbing progression.

Climber :
liana
Climber :
obligatory
Epiphyte :
terrestrial
Growth form :
shrub
Plant height mean:
10 m
Woodiness :
woody

Physiology

The physiology of Physostigma venenosum is characterized by its metabolic processes and nutrient acquisition strategies, most notably its reliance on a C3 photosynthetic pathway for carbon fixation. This means the plant utilizes the enzyme RuBisCO to incorporate atmospheric carbon dioxide directly into organic molecules during the Calvin cycle, a process typical of most temperate and tropical woody climbers. In terms of nutrient cycling and soil interaction, the plant does not function as a nitrogen fixer; it lacks the symbiotic relationship with nitrogen-fixing bacteria required to convert atmospheric nitrogen into usable forms, instead relying on the uptake of nitrates and ammonium from the soil through its root system.

Nitrogen fixer :
no
Photosynthetic pathway :
C3

Sources: Global Inventory of Floras and Traits (GIFT)

Chemicals

Physostigma venenosum has 17 reported phytochemicals identified across 0 scientific publications and several other databases. The most consistently reported chemicals include physostigmine, (-)-Physovenine, (-)-physostigmine, BETA-SITOSTEROL, Behenic acid.

Chemicals reported in Physostigma venenosum
Chemical Supporting sources Consensus
physostigmine 2 supporting sources ★☆☆☆☆
(-)-Physovenine 1 supporting sources ★☆☆☆☆
(-)-physostigmine 1 supporting sources ★☆☆☆☆
BETA-SITOSTEROL 1 supporting sources ★☆☆☆☆
Behenic acid 1 supporting sources ★☆☆☆☆
Calabarine 1 supporting sources ★☆☆☆☆
Eseramine 1 supporting sources ★☆☆☆☆
Eseridine 1 supporting sources ★☆☆☆☆
Eserine 1 supporting sources ★☆☆☆☆
Geneserine 1 supporting sources ★☆☆☆☆

physostigmine

  1. Arquivos brasileiros de oftalmologia
  2. Current Alzheimer research

(-)-Physovenine

  1. Organic letters

(-)-physostigmine

  1. Organic letters

BETA-SITOSTEROL

  1. Dr. Duke

Behenic acid

  1. Dr. Duke

Calabarine

  1. Dr. Duke

Eseramine

  1. Dr. Duke

Eseridine

  1. Dr. Duke

Eserine

  1. Dr. Duke

Geneserine

  1. Dr. Duke

Activities

Physostigma venenosum has 99 reported activities identified across 0 scientific publications and several other databases. The most consistently reported activities include 5-Alpha-Reductase-Inhibitor, Absorbent, Allergenic, Alpha-Reductase-Inhibitor, Androgenic.

Activities reported in Physostigma venenosum
Activity Supporting sources Consensus
5-Alpha-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
Absorbent 1 supporting sources ★☆☆☆☆
Allergenic 1 supporting sources ★☆☆☆☆
Alpha-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
Androgenic 1 supporting sources ★☆☆☆☆
Anemiagenic 1 supporting sources ★☆☆☆☆
Angiogenic 1 supporting sources ★☆☆☆☆
Anorexic 1 supporting sources ★☆☆☆☆
AntiMS 1 supporting sources ★☆☆☆☆
Antiacne 1 supporting sources ★☆☆☆☆

5-Alpha-Reductase-Inhibitor

  1. Dr. Duke

Absorbent

  1. Dr. Duke

Allergenic

  1. Dr. Duke

Alpha-Reductase-Inhibitor

  1. Dr. Duke

Androgenic

  1. Dr. Duke

Anemiagenic

  1. Dr. Duke

Angiogenic

  1. Dr. Duke

Anorexic

  1. Dr. Duke

AntiMS

  1. Dr. Duke

Antiacne

  1. Dr. Duke

Conditions

Physostigma venenosum has 2 reported investigations on conditions identified across 0 scientific publications and several other databases. The most consistently reported conditions include glaucoma, Alzheimer's disease.

Conditions investigated for Physostigma venenosum
Condition Supporting sources Consensus
Glaucoma 2 supporting sources ★☆☆☆☆
Alzheimer's disease 1 supporting sources ★☆☆☆☆

Glaucoma

  1. Arquivos brasileiros de oftalmologia
  2. Ciba Foundation symposium

Alzheimer's disease

  1. Current Alzheimer research