Calabar bean
Physostigma venenosum · Accepted scientific name
Scientific literature: Moderate (120 studies) · ★★★☆☆
Calabar bean, scientifically known as Physostiema venenosa, is a potent tropical climbing plant renowned for its bioactive alkaloids. Primarily recognized for containing physostigmine, it has historically been used as a powerful purgative and muscle relaxant. Today, its chemical properties remain vital in pharmacological research and neurological studies.
- Family
- Fabaceae
- Native range
- Africa
- Parts used
- Not available
- Common names
- Calabar-Bean · Ordeal-Bean · 1 more
- Scientific synonyms
- Not available
Names and Synonyms
Common Names
- calabar-bean
- ordeal-bean
- Calabar bean
Scientific Names
Accepted name
Physostigma venenosumRegional and Traditional Names
Spanish:
- Frijol de Calabar
German:
- Kalabarbohne
- Calabarbohne
- Calabar-Bohne
- Gottesurteilbohne
- Calabarbohne
French:
- Fève de Calabar
- Fève de calabar
- Fève De Calabar
- Feve de Calabar
- éseré
- fève de Calabar
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and the class Equisetopsida. Under the subclass Magnoliidae, it falls into the order Fabales and the family Fabaceae. Finally, it is identified by the genus Physostigma.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Fabales |
| Family | Fabaceae |
| Genus | Physostigma |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant, known as Physostigma venenosum, is found across several regions of West Tropical Africa. Its distribution specifically includes the nation of Ghana, where it grows in local ecosystems. It is also documented in Guinea, marking its presence in the coastal and inland areas of that country. Furthermore, the species can be located within the borders of the Ivory Coast and Liberia. Finally, the geographical range of this medicinal plant extends into Mali, completing its presence in the West Tropical African zone.
| Region | Area |
|---|---|
| West Tropical Africa | Ghana |
| West Tropical Africa | Guinea |
| West Tropical Africa | Ivory Coast |
| West Tropical Africa | Liberia |
| West Tropical Africa | Mali |
| West Tropical Africa | Nigeria |
| West Tropical Africa | Sierra Leone |
| West-Central Tropical Africa | Central African Republic |
| West-Central Tropical Africa | Cameroon |
| West-Central Tropical Africa | Congo |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Physostigma venenosum is characterized by its classification as a phanerophyte, specifically manifesting as a nanophanerophyte, where its perennating buds are located well above the soil surface. As a perennial climber, it maintains an evergreen deciduousness, ensuring that its foliage remains functional throughout its growth cycles rather than shedding seasonally. This life form strategy, functioning primarily as a phanerophyte, allows the plant to establish a robust presence in its habitat by protecting its vital reproductive and vegetative buds above the ground level.
- Deciduousness :
- evergreen
- Life form :
- phanerophyte
Morphology
The morphology of Physostigma venenosum is characterized by its significant stature, with a mean plant height reaching approximately 10 m. It functions as an obligatory climber, specifically categorized as a liana, which allows it to ascend through surrounding vegetation. While its growth form is described as shrub-like in certain contexts, its structural development is primarily that of a woody liana. This plant is strictly terrestrial in its habit, rather than epiphytic, establishing its root system in the soil to support its climbing progression.
- Climber :
- liana
- Climber :
- obligatory
- Epiphyte :
- terrestrial
- Growth form :
- shrub
- Plant height mean:
- 10 m
- Woodiness :
- woody
Physiology
The physiology of Physostigma venenosum is characterized by its metabolic processes and nutrient acquisition strategies, most notably its reliance on a C3 photosynthetic pathway for carbon fixation. This means the plant utilizes the enzyme RuBisCO to incorporate atmospheric carbon dioxide directly into organic molecules during the Calvin cycle, a process typical of most temperate and tropical woody climbers. In terms of nutrient cycling and soil interaction, the plant does not function as a nitrogen fixer; it lacks the symbiotic relationship with nitrogen-fixing bacteria required to convert atmospheric nitrogen into usable forms, instead relying on the uptake of nitrates and ammonium from the soil through its root system.
- Nitrogen fixer :
- no
- Photosynthetic pathway :
- C3
Sources: Global Inventory of Floras and Traits (GIFT)
Chemicals
Physostigma venenosum has 17 reported phytochemicals identified across 0 scientific publications and several other databases. The most consistently reported chemicals include physostigmine, (-)-Physovenine, (-)-physostigmine, BETA-SITOSTEROL, Behenic acid.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| physostigmine | 2 supporting sources | ★☆☆☆☆ |
| (-)-Physovenine | 1 supporting sources | ★☆☆☆☆ |
| (-)-physostigmine | 1 supporting sources | ★☆☆☆☆ |
| BETA-SITOSTEROL | 1 supporting sources | ★☆☆☆☆ |
| Behenic acid | 1 supporting sources | ★☆☆☆☆ |
| Calabarine | 1 supporting sources | ★☆☆☆☆ |
| Eseramine | 1 supporting sources | ★☆☆☆☆ |
| Eseridine | 1 supporting sources | ★☆☆☆☆ |
| Eserine | 1 supporting sources | ★☆☆☆☆ |
| Geneserine | 1 supporting sources | ★☆☆☆☆ |
physostigmine
- Arquivos brasileiros de oftalmologia
- Current Alzheimer research
(-)-Physovenine
- Organic letters
(-)-physostigmine
- Organic letters
BETA-SITOSTEROL
- Dr. Duke
Behenic acid
- Dr. Duke
Calabarine
- Dr. Duke
Eseramine
- Dr. Duke
Eseridine
- Dr. Duke
Eserine
- Dr. Duke
Geneserine
- Dr. Duke
Activities
Physostigma venenosum has 99 reported activities identified across 0 scientific publications and several other databases. The most consistently reported activities include 5-Alpha-Reductase-Inhibitor, Absorbent, Allergenic, Alpha-Reductase-Inhibitor, Androgenic.
| Activity | Supporting sources | Consensus |
|---|---|---|
| 5-Alpha-Reductase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| Absorbent | 1 supporting sources | ★☆☆☆☆ |
| Allergenic | 1 supporting sources | ★☆☆☆☆ |
| Alpha-Reductase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| Androgenic | 1 supporting sources | ★☆☆☆☆ |
| Anemiagenic | 1 supporting sources | ★☆☆☆☆ |
| Angiogenic | 1 supporting sources | ★☆☆☆☆ |
| Anorexic | 1 supporting sources | ★☆☆☆☆ |
| AntiMS | 1 supporting sources | ★☆☆☆☆ |
| Antiacne | 1 supporting sources | ★☆☆☆☆ |
5-Alpha-Reductase-Inhibitor
- Dr. Duke
Absorbent
- Dr. Duke
Allergenic
- Dr. Duke
Alpha-Reductase-Inhibitor
- Dr. Duke
Androgenic
- Dr. Duke
Anemiagenic
- Dr. Duke
Angiogenic
- Dr. Duke
Anorexic
- Dr. Duke
AntiMS
- Dr. Duke
Antiacne
- Dr. Duke
Conditions
Physostigma venenosum has 2 reported investigations on conditions identified across 0 scientific publications and several other databases. The most consistently reported conditions include glaucoma, Alzheimer's disease.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Glaucoma | 2 supporting sources | ★☆☆☆☆ |
| Alzheimer's disease | 1 supporting sources | ★☆☆☆☆ |
Glaucoma
- Arquivos brasileiros de oftalmologia
- Ciba Foundation symposium
Alzheimer's disease
- Current Alzheimer research