Medicinal Herbs
Phyllanthus niruri · Accepted scientific name
Scientific literature: Very Extensive (498 studies) · ★★★★★
Medicinal Herbs, scientifically known as Phyllanthus niruri, is a versatile plant widely revered in traditional Ayurvedic medicine. Often called "stonebreaker," it is celebrated for its potent hepatoprotective and diuretic properties. This small herb plays a vital role in supporting liver health and managing kidney stones through its bioactive compounds.
- Family
- Phyllanthaceae
- Native range
- Northern America
- Parts used
- Leaf
- Common names
- Stone Breaker Tea
- Scientific synonyms
- Nymphanthus Niruri · Diasperus Niruri
Names and Synonyms
Common Names
- stone breaker tea
Scientific Names
Accepted name
Phyllanthus niruriSynonyms
- Nymphanthus niruri
- Diasperus niruri
Regional and Traditional Names
Spanish:
- Phyllanthus rosellus
- Phyllanthus lathyroides
- Phyllanthus humilis
- Chanca piedra
- Nymphanthus niruri
- Niruris indica
- Phyllanthus kirganella
- Phyllanthus chlorophaeus
- Quebra pedra
- Phyllanthus filiformis
- Diasperus lathyroides
- Diasperus rosellus
- Phyllanthus lathyroides var. commutatus
- Niruris annua
- Phyllanthus carolinianus
- Phyllanthus amarus
- chancapiedra
- quinina criolla
- Barbasquillo
- Dormilona
- Rompe piedras
German:
- Niruri
- Steinbrecher
French:
- derrière dos
- quinine créole
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it is further categorized under the order Malpighiales and the family Phyllanthaceae. Finally, it is identified by the genus Phyllanthus.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malpighiales |
| Family | Phyllanthaceae |
| Genus | Phyllanthus |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a widespread distribution across several key regions in North America. In the United States, its presence is specifically noted within the state of Texas in the South-Central region. Moving into Mexico, it can be found throughout the diverse landscapes of Mexico Central. The species also extends into the coastal and inland areas of Mexico Gulf. Finally, its range reaches the varied terrains of Mexico Northwest, completing its regional footprint.
| Region | Area |
|---|---|
| South-Central U.S.A. | Texas |
| Mexico | Mexico Central |
| Mexico | Mexico Northeast |
| Mexico | Mexico Gulf |
| Mexico | Mexico Northwest |
| Mexico | Mexico Southwest |
| Mexico | Mexico Southeast |
| Central America | Belize |
| Central America | Costa Rica |
| Central America | Honduras |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Phyllanthus niruri is characterized by remarkable adaptability across diverse and varied environments, ranging from coastal ecosystems to high-altitude terrains. It thrives in a wide array of habitats, including anthropogenic areas, Caatinga (strictu sensu), Campinarana, Campo de Várzea, Campo Limpo, Cerrado (lato sensu), Floresta Ombrófila (pluvial forest), and Restinga. This environmental plasticity is further reflected in its significant altitudinal distribution, which spans from sea level up to a maximum elevation of 3000 m AMSL. With an average elevational range of approximately 1880 m AMSL, the species demonstrates a robust capacity to occupy both lowland tropical regions and much higher montane zones.
- Elevational range max:
- 3000 m AMSL
- Elevational range mean:
- 1880 m AMSL
- Elevational range min:
- 0 m AMSL
- Habitat :
- Área Antrópica, Caatinga (stricto sensu), Campinarana, Campo de Várzea, Campo Limpo, Cerrado (lato sensu), Floresta Ombrófila (= Floresta Pluvial), Restinga
Life history
The life history of Phyllanthus niruri is characterized by an annual lifecycle, completing its entire biological process from germination to seed production within a single growing season. As a therophyte, the plant adopts a strategy of surviving unfavorable environmental conditions through highly resilient seeds rather than persistent vegetative structures, allowing it to rapidly colonize disturbed areas or seasonal habitats. This life form is further classified under the therophyte category, signifying that the individual plant dies at the end of the season, leaving behind seeds that remain dormant until the next period of favorable moisture and temperature.
- Life form :
- therophyte
- Lifecycle :
- annual
Morphology
The morphology of Phyllanthus niruri is characterized by its classification as a non-woody herb and specifically a forb. It functions as a self-supporting plant, lacking the climbing mechanisms of a liana or vine, and grows as an independent organism rather than a parasite or epiphyte. The plant is strictly terrestrial in its habitat and does not exhibit aquatic or semiaquatic tendencies. In terms of stature, it is a relatively small species with a mean plant height of approximately 0.3 m, though it can reach a maximum height of about 0.457 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Growth form :
- forb
- Parasite :
- independent
- Plant height max:
- 0.457200914 m
- Plant height mean:
- 0.3 m
- Woodiness :
- non-woody
Physiology
The physiology of Phyllanthus niruri is characterized by a non-succulent growth habit, as it lacks the specialized parenchyma tissues required for significant water storage within its stems or leaves, necessitating a consistent moisture environment to maintain turgor pressure. It does not function as a nitrogen fixer, meaning it lacks the symbiotic relationship with rhizobia or actinomycetes required to convert atmospheric nitrogen into bioavailable forms, relying instead on the uptake of nitrates and ammonium from the soil through its root system. The plant's metabolic processes are centered around the synthesis of diverse secondary metabolites, such as lignans, flavonoids, and tannins, which are produced through complex biochemical pathways to serve as defense mechanisms. Its photosynthetic efficiency is driven by standard C3 pathways, utilizing chlorophyll to convert solar energy into chemical energy, while its transpiration rates are regulated by stomatal movement to balance gas exchange with water loss in its typical tropical or subtropical habitats.
- Nitrogen fixer :
- no
- Succulence :
- no
Reproduction
The reproduction of Phyllanthus niruri is characterized by a broad and flexible flowering period that can span nearly the entire year, typically beginning in September and concluding in October, though the specific timing remains highly variable. Regarding its seed dispersal mechanisms, the plant utilizes an autochorous syndrome, meaning it relies on internal mechanisms for seed dispersal rather than external agents. This autochorous trait is consistently observed across its reproductive cycles, facilitating the spread of its progeny through self-dispersal methods.
- Dispersal syndrome :
- autochorous
- Flowering time :
- Sep
- Flowering time :
- Oct
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Phyllanthus niruri has 1 reported plant parts identified across 7 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Leaf | 7 supporting sources | ★★★★☆ |
Leaf
- Pharmaceutical biology
- Natural product research
- BMC complementary and alternative medicine
- Journal of ethnopharmacology
- Interdisciplinary toxicology
View 2 additional sources
- Iranian journal of veterinary research
- Journal of clinical and diagnostic research : JCDR
Chemicals
Phyllanthus niruri has 77 reported phytochemicals identified across 7 scientific publications and several other databases. The most consistently reported chemicals include Gallic acid, Flavonoids, Hypophyllanthin, Phyllanthin, ellagic acid.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Gallic acid | 5 supporting sources | ★★★☆☆ |
| Flavonoids | 4 supporting sources | ★★☆☆☆ |
| Hypophyllanthin | 4 supporting sources | ★★☆☆☆ |
| Phyllanthin | 4 supporting sources | ★★☆☆☆ |
| ellagic acid | 4 supporting sources | ★★☆☆☆ |
| Brevifolin carboxylic acid | 3 supporting sources | ★★☆☆☆ |
| Lignans | 3 supporting sources | ★★☆☆☆ |
| Tannins | 3 supporting sources | ★★☆☆☆ |
| quercetin | 3 supporting sources | ★★☆☆☆ |
| Astragalin | 2 supporting sources | ★☆☆☆☆ |
Gallic acid
- Molecules (Basel, Switzerland)
- Natural product research
- BMC complementary and alternative medicine
- Phytotherapy research : PTR
- Journal of natural products
Flavonoids
- PloS one
- Current pharmaceutical design
- The Journal of pharmacy and pharmacology
- Antibiotics (Basel, Switzerland)
Hypophyllanthin
- Molecules (Basel, Switzerland)
- Natural product research
- Journal of ethnopharmacology
- Environmental monitoring and assessment
Phyllanthin
- Dr. Duke
- Tropical life sciences research
- Journal of ethnopharmacology
- Environmental monitoring and assessment
ellagic acid
- Chemical & pharmaceutical bulletin
- Natural product research
- Phytotherapy research : PTR
- Journal of pharmaceutical analysis
Brevifolin carboxylic acid
- Dr. Duke
- Chemical & pharmaceutical bulletin
- Natural product research
Lignans
- Current pharmaceutical design
- The Journal of pharmacy and pharmacology
- Planta medica
Tannins
- Current pharmaceutical design
- The Journal of pharmacy and pharmacology
- Antibiotics (Basel, Switzerland)
quercetin
- Dr. Duke
- Molecules (Basel, Switzerland)
- Journal of pharmaceutical analysis
Astragalin
- Dr. Duke
- Natural product research
Activities
Phyllanthus niruri has 265 reported activities identified across 7 scientific publications and several other databases. The most consistently reported activities include Hepatoprotective, Antiviral, Antibacterial, Antidiabetic, Antioxidant.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Hepatoprotective | 6 supporting sources | ★★★☆☆ |
| Antiviral | 5 supporting sources | ★★★☆☆ |
| Antibacterial | 4 supporting sources | ★★☆☆☆ |
| Antidiabetic | 4 supporting sources | ★★☆☆☆ |
| Antioxidant | 4 supporting sources | ★★☆☆☆ |
| Anticancer | 3 supporting sources | ★★☆☆☆ |
| Immunostimulant | 3 supporting sources | ★★☆☆☆ |
| Analgesic | 2 supporting sources | ★☆☆☆☆ |
| Antihepatotoxic | 2 supporting sources | ★☆☆☆☆ |
| Antispasmodic | 2 supporting sources | ★☆☆☆☆ |
Hepatoprotective
- Dr. Duke
- Chemistry & biodiversity
- Current pharmaceutical design
- Indian journal of physiology and pharmacology
- Asian Pacific journal of cancer prevention : APJCP
View 1 additional sources
- Vegetos (Bareilly, India)
Antiviral
- Dr. Duke
- Current pharmaceutical design
- BioMed research international
- Asian Pacific journal of cancer prevention : APJCP
- Applied microbiology and biotechnology
Antibacterial
- Dr. Duke
- Environmental pollution (Barking, Essex : 1987)
- Current pharmaceutical design
- Asian Pacific journal of cancer prevention : APJCP
Antidiabetic
- Dr. Duke
- Journal of pharmaceutical and biomedical analysis
- Current pharmaceutical design
- Asian Pacific journal of cancer prevention : APJCP
Antioxidant
- Dr. Duke
- Molecules (Basel, Switzerland)
- Chemistry & biodiversity
- BMC complementary medicine and therapies
Anticancer
- Dr. Duke
- Evidence-based complementary and alternative medicine : eCAM
- Current pharmaceutical design
Immunostimulant
- Dr. Duke
- Journal of toxicology
- Iranian journal of veterinary research
Analgesic
- Dr. Duke
- Asian Pacific journal of cancer prevention : APJCP
Antihepatotoxic
- Dr. Duke
- Journal of ethnopharmacology
Antispasmodic
- Dr. Duke
- Asian Pacific journal of cancer prevention : APJCP
Medicinal Uses
Phyllanthus niruri has 54 reported medicinal uses identified across 7 scientific publications and several other databases. The most consistently reported uses include kidney stones, malaria, Helicobacter pylori, Plasmodium falciparum, chronic hepatitis B.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| kidney stones | Pharmaceutical biology (and other 4 sources) | ★★☆☆☆ |
| malaria | Pharmaceutical biology (and other 4 sources) | ★★☆☆☆ |
| Helicobacter pylori | Phytotherapy research : PTR (and other 2 sources) | ★☆☆☆☆ |
| Plasmodium falciparum | Parasitology research (and other 2 sources) | ★☆☆☆☆ |
| chronic hepatitis B | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 2 sources) | ★☆☆☆☆ |
| hypertension | Biological trace element research (and other 2 sources) | ★☆☆☆☆ |
| inflammation | Plants (Basel, Switzerland) (and other 2 sources) | ★☆☆☆☆ |
| jaundice | Biological trace element research (and other 2 sources) | ★☆☆☆☆ |
| obesity | Journal of pharmaceutical and biomedical analysis (and other 2 sources) | ★☆☆☆☆ |
| ovarian cancer | BMC complementary and alternative medicine (and other 2 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| aqueous leaf extract | Pharmaceutical biology (and other 3 sources) | ★★☆☆☆ |
| aqueous extract | Natural product research (and other 2 sources) | ★☆☆☆☆ |
| 2% aqueous KOH | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| 70% ethanolic extract | Chemical & pharmaceutical bulletin (and other 1 sources) | ★☆☆☆☆ |
| A dry extract | Experimental biology and medicine (Maywood, N.J.) (and other 1 sources) | ★☆☆☆☆ |
| AgNPs | Applied microbiology and biotechnology (and other 1 sources) | ★☆☆☆☆ |
| Aqueous extraction | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| HP-1 | Human & experimental toxicology (and other 1 sources) | ★☆☆☆☆ |
| Isoamyl alcohol fractions | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Phyllanthus niruri extract | Journal of pharmaceutical and biomedical analysis (and other 1 sources) | ★☆☆☆☆ |