10 Possible Side Effects Of Phyllanthus Amarus (Phyllanthus)

Phyllanthus amarus has some side effects when used improperly, such as nausea, stomach pain, and diarrhea.

These side effects can occur if the herb is taken in excessive amounts or without sufficient water intake, causing dehydration and electrolyte imbalance.

For instance, a person suffering from nausea may be unable to eat or maintain their daily routine, while stomach pain can disrupt their work and social life, leading to stress and fatigue.

This article explains in details the 10 most common side effects of Phyllanthus amarus if used imporperly.

1. Causes kidney failure develops

Phyllanthus amarus increases blood sugar levels by interfering with the body's ability to regulate glucose metabolism.

The saponins present in this herb can inhibit the activity of enzymes responsible for glucose uptake and utilization in cells, leading to a rise in blood sugar levels.

Additionally, Phyllanthus amarus may also stimulate the release of stress hormones, such as cortisol, which can further exacerbate hyperglycemia.

2. Causes kidney failure develops

Phyllanthus amarus causes skin rashes appears due to its ability to stimulate the immune system, leading to an allergic reaction in some individuals.

The saponins and flavonoids present in Phyllanthus amarus may trigger an inflammatory response, resulting in the development of itchy, red, and swollen patches on the skin.

Additionally, the herb's antitumor properties may also contribute to its ability to cause skin reactions, as it can stimulate the production of histamine and other chemicals that can lead to allergic responses.

3. Causes kidney failure develops

Phyllanthus amarus produces kidney stone formation due to its high concentration of oxalates and calcium.

These substances can increase the levels of these minerals in the urine, leading to crystallization and stone formation within the kidneys or urinary tract.

The herb's ability to bind to bile acids may also contribute to this side effect by altering the body's absorption and excretion patterns, ultimately increasing the risk of kidney stones.

4. Causes kidney failure develops

Phyllanthus amarus induces gastrointestinal disturbances.

The presence of alkaloids, flavonoids, and other bioactive compounds in the plant may cause stomach upset, nausea, diarrhea, or abdominal pain due to its ability to alter gut motility and mucosal integrity.

Additionally, Phyllanthus amarus's anti-inflammatory properties can also lead to irritation and inflammation of the gastrointestinal tract, further contributing to these adverse effects.

5. Causes kidney failure develops

6. Causes kidney failure develops

Phyllanthus amarus enhances bleeding risk increases.

This may be due to its ability to inhibit platelet aggregation and antagonize vitamin K-dependent coagulation factors. Additionally, Phyllanthus amarus contains flavonoids and other bioactive compounds that can increase the production of prostacyclin, a potent vasodilator that may further exacerbate bleeding tendencies.

As a result, individuals taking Phyllanthus amarus may experience increased bruising, petechiae, or other forms of bleeding.

7. Causes kidney failure develops

Phyllanthus amarus decreases platelet count drops due to its ability to inhibit platelet aggregation and reduce blood clotting.

This is because the plant's active compounds, such as phyllanthin and hypophyllanthin, have been shown to have anti-coagulant properties, which can lead to a decrease in platelet count and potentially increase the risk of bleeding complications.

As a result, individuals using Phyllanthus amarus may experience symptoms related to low platelet counts, such as easy bruising, petechiae, or prolonged bleeding from cuts or injuries.

8. Causes kidney failure develops

Phyllanthus amarus interferes with liver function affecting its ability to process toxins and metabolize medications.

This is because the herb contains compounds that can inhibit certain liver enzymes, leading to alterations in liver function tests and potentially causing liver damage or failure in rare cases.

The exact mechanism behind this interaction remains unclear, but it is thought to be related to the herb's ability to induce oxidative stress and inflammation within the liver tissue.

9. Causes kidney failure develops

Phyllanthus amarus causes thyroid dysfunction to develop in some individuals.

This is due to its ability to inhibit the conversion of thyroxine (T4) to triiodothyronine (T3), leading to hypothyroidism or an underactive thyroid gland.

Additionally, Phyllanthus amarus may also increase the levels of thyroid-stimulating hormone (TSH), further exacerbating the condition.

10. Causes kidney failure develops

Phyllanthus amarus affects blood pressure levels changes.

This herb may cause fluctuations in blood pressure due to its ability to alter the balance of various chemicals in the body, such as serotonin and dopamine.

Additionally, it has been shown to increase the activity of enzymes that affect blood vessel constriction and dilation, which can lead to changes in blood pressure.