Phlomoides rotata
Phlomoides rotata · Accepted scientific name
Scientific literature: Very Sparse (2 studies) · ★☆☆☆☆
Phlomoides rotata is a versatile medicinal plant whose therapeutic potential is derived from its roots, leaves, and stems. Various preparations, including aqueous extracts, boiling water extractions, and 95% EtOH extracts of the roots, are utilized to harness its bioactive properties. The plant contains key chemical compounds such as chlorogenic acid, shanzhiside methyl ester, and acetylated derivatives like 8-O-acetyl shanzhiside methylester and 6-O-acetyl shanzhiside methylester. These constituents contribute to significant biological activities, most notably antioxidant and hemostatic effects. Consequently, this species shows great promise in managing inflammation, providing analgesia, improving blood circulation, and aiding in the healing of bone fractures.
- Synonyms
- Not available
- Common names
- Not available
- Family
- Not available
- Distribution
- Not available
- Plant Parts
- Root · Leaf
Classification
Distribution
Identification
Biological Activities
Phlomoides rotata, also known as Lamiophlomis rotata, is a traditional Tibetan medicinal herb that possesses significant pharmacological properties. Scientific investigations have demonstrated that the plant exhibits notable antioxidant capacity, particularly within its aerial parts. Furthermore, research focusing on the enrichment of its iridoid glycosides has highlighted its effective hemostatic activity. By utilizing optimized purification processes, researchers can isolate these bioactive compounds to enhance the herb's medicinal utility. Consequently, understanding the chemical profiles of both the aerial and underground parts is essential for effective therapeutic application.
Compounds
Phlomoides rotata is a medicinal plant known for its complex chemical profile, which includes several significant iridoid glycosides. Research has confirmed that the plant contains shanzhiside methyl ester and its acetylated derivatives, specifically 6-O-acetyl shanzhiside methylester and 8-O-acetyl shanzhiside methylester. Additionally, chlorogenic acid is identified as a key constituent within its chemical makeup. These various compounds contribute to the plant's diverse biological activities, which are essential for its use in traditional medicines. Understanding these specific relationships helps researchers ensure the quality and efficacy of preparations derived from this species.
Conditions
Phlomoides rotata serves as an effective treatment for inflammation and the reduction of swelling in various biological models. It is also utilized in the management of rheumatoid arthritis (RA) by regulating metabolism and diminishing joint tissue damage. Regarding blood coagulation, the plant is associated with the treatment of PT decurtation through its hemostatic effects. While some studies noted no change in activated partial thromboplastin time (APTT), the plant's influence on blood parameters remains a key area of medicinal study. Collectively, these properties demonstrate the diverse therapeutic capabilities of the species.
Preparations
Phlomoides rotata is prepared as a 95% EtOH extract of the roots to isolate specific iridoid lactones like lamiolactone. The plant is also prepared as aerial parts, which contain a diverse composition of compounds and high antioxidant capacity. Additionally, Phlomoides rotata is prepared as an aqueous extract to enrich the hemostatic active part known as total iridoid glycosides. Research comparing different methods shows the plant can be prepared as a boiling water extraction, though ethanol extraction often yields higher flavonoid content. Finally, Phlomoides rotata is prepared as crude medicinal materials, with studies suggesting that dosage should be increased when using the aerial parts instead of the underground parts.
Parts used
Phlomoides rotata, also known as Lamiophlomis rotata, is a significant medicinal herb characterized by its diverse biological components. Research indicates that the plant consists of distinct structural parts, specifically the root, stem, and leaf. Studies on endophytic bacterial diversity show that the LH-PCR profiles of the root, stem, and leaf exhibit a high level of similarity within the species. Furthermore, the chemical composition and antioxidant capacities can vary between the underground roots and the aerial parts, which include the stem and leaves. Understanding these specific botanical relationships is essential for optimizing the medicinal use and gene expression analysis of this unique species.