Amur cork-tree
Phellodendron amurense · Accepted scientific name
Scientific literature: Very Extensive (457 studies) · ★★★★★
Amur cork-tree, scientifically known as Phellodendron amurense, is a deciduous tree prized in traditional medicine. Its bitter, yellow inner bark contains alkaloids like berberine, offering potent anti-inflammatory, antibacterial, and digestive benefits. Widely utilized in East Asian therapies, it serves as a vital natural remedy for various systemic ailments.
Names
Common Names
- Amur cork-tree
- Chinese cork-tree
- Japanese cork-tree
- northern cork-tree
- phellodendron
- Chinese corktree
- phellodendron-bark
Regional and Traditional Names
Spanish:
- Phellodendron amurense var. sachalinense
- Phellodendron japonicum
- Phellodendron lavalleei
- Phellodendron sachalinense
- Phellodendron wilsonii
- Phellodendron amurense var sachalinense
German:
- Amur-Korkbaum
- Amurkorkbaum
- Amur-Korkbaum
French:
- arbre liège de Chine
- arbre à liège de l'Amour
- phellodendre de l'Amour
- phellodendron de Sibérie
- phellodendron de l'Amour
Scientific Names
Accepted name
Phellodendron amurenseSynonyms
- Phellodendron insulare
- Phellodendron amurense var. suberosum
- Phellodendron japonicum
- Phellodendron molle
- Phellodendron nikkomontanum
- Phellodendron piriforme
- Phellodendron lavalleei
- Phellodendron kodamanum
- Phellodendron amurense var. molle
- Phellodendron amurense f. molle
- Phellodendron amurense var. lavalleei
- Phellodendron sachalinense
- Phellodendron amurense f. insulare
- Phellodendron amurense f. suberosum
- Phellodendron sachalinense var. suberosum
- Phellodendron amurense var. sachalinense
- Phellodendron sachalinense f. longipes
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Sapindales and the family Rutaceae. It is specifically identified by the genus Phelloodendron.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Sapindales | WCVP |
| Family | Rutaceae | WCVP |
| Genus | Phellodendron | WCVP |
Distribution
This plant exhibits a broad geographical distribution that spans across distinct regions of Eurasia. In Southeastern Europe, its presence is documented within the territories of Bulgaria and Romania. Moving toward the Asian continent, the species is found extensively throughout the Russian Far East. Specifically, it inhabits the Amur and Khabarovsk regions of this vast area. Additionally, the plant can be located as far east as the Kuril Islands.
| Region | Area | Source |
|---|---|---|
| Southeastern Europe | Bulgaria | WCVP |
| Southeastern Europe | Romania | WCVP |
| Russian Far East | Amur | WCVP |
| Russian Far East | Khabarovsk | WCVP |
| Russian Far East | Kuril Is. | WCVP |
| Russian Far East | Primorye | WCVP |
| Russian Far East | Sakhalin | WCVP |
| Central Asia | Tadzhikistan | WCVP |
| Central Asia | Uzbekistan | WCVP |
| China | Inner Mongolia | WCVP |
Plant Parts
This plant, Phellodendron amurense, possesses several distinct anatomical components that are utilized for its medicinal properties. The therapeutic compounds are primarily concentrated within the bark, specifically within the outer bark layer which is often harvested for traditional remedies. Below the surface, the root also serves as a vital part of the plant's structure and medicinal profile. While the leaves contribute to the plant's overall physiological processes, other botanical structures such as the pericarp are characteristic of its reproductive development.| Plant Part | Sources | Consensus |
|---|---|---|
| fruit | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (and other 1 sources) | ★☆☆☆☆ |
| leaf | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (and other 1 sources) | ★☆☆☆☆ |
| root | Frontiers in plant science (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Phellodendron amurense has 45 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include berberine, Jatrorrhizine, Magnoflorine, Palmatine, Phellodendrine.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| berberine | 9 supporting sources | ★★★★☆ |
| Jatrorrhizine | 6 supporting sources | ★★★☆☆ |
| Magnoflorine | 6 supporting sources | ★★★☆☆ |
| Palmatine | 6 supporting sources | ★★★☆☆ |
| Phellodendrine | 4 supporting sources | ★★☆☆☆ |
| Obaculactone | 3 supporting sources | ★★☆☆☆ |
| Obacunone | 3 supporting sources | ★★☆☆☆ |
| Limonin | 2 supporting sources | ★☆☆☆☆ |
| 7-Dehydrostigmasterol | 1 supporting sources | ★☆☆☆☆ |
| Amurensine | 1 supporting sources | ★☆☆☆☆ |
berberine
- Dr. Duke
- Molecules (Basel, Switzerland)
- Frontiers in plant science
- Journal of natural medicines
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
View 4 additional sources
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of separation science
- Evidence-based complementary and alternative medicine : eCAM
- The Journal of antimicrobial chemotherapy
Jatrorrhizine
- Dr. Duke
- Molecules (Basel, Switzerland)
- Frontiers in plant science
- Journal of separation science
- Phytomedicine : international journal of phytotherapy and phytopharmacology
View 1 additional sources
- Archives of pharmacal research
Magnoflorine
- Dr. Duke
- Planta medica
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Molecules (Basel, Switzerland)
- Frontiers in plant science
View 1 additional sources
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Palmatine
- Dr. Duke
- Molecules (Basel, Switzerland)
- Frontiers in plant science
- Journal of separation science
- Phytomedicine : international journal of phytotherapy and phytopharmacology
View 1 additional sources
- The Journal of antimicrobial chemotherapy
Phellodendrine
- Dr. Duke
- Planta medica
- Molecules (Basel, Switzerland)
- Frontiers in plant science
Obaculactone
- Dr. Duke
- Molecules (Basel, Switzerland)
- Evidence-based complementary and alternative medicine : eCAM
Obacunone
- Dr. Duke
- Molecules (Basel, Switzerland)
- Evidence-based complementary and alternative medicine : eCAM
Limonin
- Dr. Duke
- Journal of natural medicines
7-Dehydrostigmasterol
- Dr. Duke
Amurensine
- Dr. Duke
Activities
Phellodendron amurense has 322 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Anticancer, Antioxidant, Antiangiogenic, Antibacterial, (+)-Inotropic.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Anticancer | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Antioxidant | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Antiangiogenic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antibacterial | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| (+)-Inotropic | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| ACE-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Abortifacient | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Adrenocorticotrophic | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Adrenolytic | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Aldose-Reductase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Phellodendron amurense has 32 reported medicinal uses identified across 3 scientific publications and several other databases. The most consistently reported uses include anxiety, Anger, Candida albicans, Candida glabrata, Candida parapsilosis.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| anxiety | Alternative therapies in health and medicine (and other 2 sources) | ★☆☆☆☆ |
| Anger | Journal of the International Society of Sports Nutrition (and other 1 sources) | ★☆☆☆☆ |
| Candida albicans | The Journal of antimicrobial chemotherapy (and other 1 sources) | ★☆☆☆☆ |
| Candida glabrata | The Journal of antimicrobial chemotherapy (and other 1 sources) | ★☆☆☆☆ |
| Candida parapsilosis | The Journal of antimicrobial chemotherapy (and other 1 sources) | ★☆☆☆☆ |
| Confusion | Journal of the International Society of Sports Nutrition (and other 1 sources) | ★☆☆☆☆ |
| Depression | Journal of the International Society of Sports Nutrition (and other 1 sources) | ★☆☆☆☆ |
| Fatigue | Journal of the International Society of Sports Nutrition (and other 1 sources) | ★☆☆☆☆ |
| abdominal pain | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| atopic dermatitis | Evidence-based complementary and alternative medicine : eCAM (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| Phellodendri Cortex | Archives of pharmacal research (and other 2 sources) | ★☆☆☆☆ |
| bark | Planta medica (and other 1 sources) | ★☆☆☆☆ |
| diet supplement | Fish & shellfish immunology (and other 1 sources) | ★☆☆☆☆ |
| extracts | Fitoterapia (and other 1 sources) | ★☆☆☆☆ |
| soaked pericarp of P. amurense in distilled water at 4 degrees C | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |