Amur cork-tree

Phellodendron amurense · Accepted scientific name

Scientific literature: Very Extensive (457 studies) · ★★★★★

Amur cork-tree, scientifically known as Phellodendron amurense, is a deciduous tree prized in traditional medicine. Its bitter, yellow inner bark contains alkaloids like berberine, offering potent anti-inflammatory, antibacterial, and digestive benefits. Widely utilized in East Asian therapies, it serves as a vital natural remedy for various systemic ailments.

Family
Rutaceae
Native range
Europe
Parts used
Fruit · Leaf
Common names
Amur Cork-Tree · Chinese Cork-Tree · 5 more
Scientific synonyms
Phellodendron Insulare · Phellodendron Amurense Var. Suberosum · 15 more

Names

Common Names

Regional and Traditional Names

Spanish:

  • Phellodendron amurense var. sachalinense
  • Phellodendron japonicum
  • Phellodendron lavalleei
  • Phellodendron sachalinense
  • Phellodendron wilsonii
  • Phellodendron amurense var sachalinense

German:

  • Amur-Korkbaum
  • Amurkorkbaum
  • Amur-Korkbaum

French:

  • arbre liège de Chine
  • arbre à liège de l'Amour
  • phellodendre de l'Amour
  • phellodendron de Sibérie
  • phellodendron de l'Amour

Scientific Names

Accepted name

Phellodendron amurense

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Sapindales and the family Rutaceae. It is specifically identified by the genus Phelloodendron.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Sapindales WCVP
Family Rutaceae WCVP
Genus Phellodendron WCVP

Distribution

This plant exhibits a broad geographical distribution that spans across distinct regions of Eurasia. In Southeastern Europe, its presence is documented within the territories of Bulgaria and Romania. Moving toward the Asian continent, the species is found extensively throughout the Russian Far East. Specifically, it inhabits the Amur and Khabarovsk regions of this vast area. Additionally, the plant can be located as far east as the Kuril Islands.

Region Area Source
Southeastern Europe Bulgaria WCVP
Southeastern Europe Romania WCVP
Russian Far East Amur WCVP
Russian Far East Khabarovsk WCVP
Russian Far East Kuril Is. WCVP
Russian Far East Primorye WCVP
Russian Far East Sakhalin WCVP
Central Asia Tadzhikistan WCVP
Central Asia Uzbekistan WCVP
China Inner Mongolia WCVP

Plant Parts

This plant, Phellodendron amurense, possesses several distinct anatomical components that are utilized for its medicinal properties. The therapeutic compounds are primarily concentrated within the bark, specifically within the outer bark layer which is often harvested for traditional remedies. Below the surface, the root also serves as a vital part of the plant's structure and medicinal profile. While the leaves contribute to the plant's overall physiological processes, other botanical structures such as the pericarp are characteristic of its reproductive development.
Plant Part Sources Consensus
fruit Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (and other 1 sources) ★☆☆☆☆
leaf Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (and other 1 sources) ★☆☆☆☆
root Frontiers in plant science (and other 1 sources) ★☆☆☆☆

Chemicals

Phellodendron amurense has 45 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include berberine, Jatrorrhizine, Magnoflorine, Palmatine, Phellodendrine.

Chemicals reported in Phellodendron amurense
Chemical Supporting sources Consensus
berberine 9 supporting sources ★★★★☆
Jatrorrhizine 6 supporting sources ★★★☆☆
Magnoflorine 6 supporting sources ★★★☆☆
Palmatine 6 supporting sources ★★★☆☆
Phellodendrine 4 supporting sources ★★☆☆☆
Obaculactone 3 supporting sources ★★☆☆☆
Obacunone 3 supporting sources ★★☆☆☆
Limonin 2 supporting sources ★☆☆☆☆
7-Dehydrostigmasterol 1 supporting sources ★☆☆☆☆
Amurensine 1 supporting sources ★☆☆☆☆

berberine

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Frontiers in plant science
  4. Journal of natural medicines
  5. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
View 4 additional sources
  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. Journal of separation science
  3. Evidence-based complementary and alternative medicine : eCAM
  4. The Journal of antimicrobial chemotherapy

Jatrorrhizine

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Frontiers in plant science
  4. Journal of separation science
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology
View 1 additional sources
  1. Archives of pharmacal research

Magnoflorine

  1. Dr. Duke
  2. Planta medica
  3. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  4. Molecules (Basel, Switzerland)
  5. Frontiers in plant science
View 1 additional sources
  1. Phytomedicine : international journal of phytotherapy and phytopharmacology

Palmatine

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Frontiers in plant science
  4. Journal of separation science
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology
View 1 additional sources
  1. The Journal of antimicrobial chemotherapy

Phellodendrine

  1. Dr. Duke
  2. Planta medica
  3. Molecules (Basel, Switzerland)
  4. Frontiers in plant science

Obaculactone

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Evidence-based complementary and alternative medicine : eCAM

Obacunone

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Evidence-based complementary and alternative medicine : eCAM

Limonin

  1. Dr. Duke
  2. Journal of natural medicines

7-Dehydrostigmasterol

  1. Dr. Duke

Amurensine

  1. Dr. Duke

Activities

Phellodendron amurense has 322 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Anticancer, Antioxidant, Antiangiogenic, Antibacterial, (+)-Inotropic.

Most Reported Activities

Activity Sources Consensus
Anticancer Dr. Duke (and other 3 sources) ★★☆☆☆
Antioxidant Dr. Duke (and other 3 sources) ★★☆☆☆
Antiangiogenic Dr. Duke (and other 2 sources) ★☆☆☆☆
Antibacterial Dr. Duke (and other 2 sources) ★☆☆☆☆
(+)-Inotropic Dr. Duke (and other 1 sources) ★☆☆☆☆
ACE-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
Abortifacient Dr. Duke (and other 1 sources) ★☆☆☆☆
Adrenocorticotrophic Dr. Duke (and other 1 sources) ★☆☆☆☆
Adrenolytic Dr. Duke (and other 1 sources) ★☆☆☆☆
Aldose-Reductase-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Phellodendron amurense has 32 reported medicinal uses identified across 3 scientific publications and several other databases. The most consistently reported uses include anxiety, Anger, Candida albicans, Candida glabrata, Candida parapsilosis.

Most Reported Uses

Use Sources Consensus
anxiety Alternative therapies in health and medicine (and other 2 sources) ★☆☆☆☆
Anger Journal of the International Society of Sports Nutrition (and other 1 sources) ★☆☆☆☆
Candida albicans The Journal of antimicrobial chemotherapy (and other 1 sources) ★☆☆☆☆
Candida glabrata The Journal of antimicrobial chemotherapy (and other 1 sources) ★☆☆☆☆
Candida parapsilosis The Journal of antimicrobial chemotherapy (and other 1 sources) ★☆☆☆☆
Confusion Journal of the International Society of Sports Nutrition (and other 1 sources) ★☆☆☆☆
Depression Journal of the International Society of Sports Nutrition (and other 1 sources) ★☆☆☆☆
Fatigue Journal of the International Society of Sports Nutrition (and other 1 sources) ★☆☆☆☆
abdominal pain Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
atopic dermatitis Evidence-based complementary and alternative medicine : eCAM (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
Phellodendri Cortex Archives of pharmacal research (and other 2 sources) ★☆☆☆☆
bark Planta medica (and other 1 sources) ★☆☆☆☆
diet supplement Fish & shellfish immunology (and other 1 sources) ★☆☆☆☆
extracts Fitoterapia (and other 1 sources) ★☆☆☆☆
soaked pericarp of P. amurense in distilled water at 4 degrees C Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) ★☆☆☆☆