Phaleria macrocarpa

Phaleria macrocarpa · Accepted scientific name

Scientific literature: Sparse (60 studies) · ★★☆☆☆

Scientifically known as Phaleria macrocarpa, is a medicinal shrub native to Indonesia, commonly referred to as Mahkota Dewa. Renowned for its powerful antioxidant properties, the plant's fruits and leaves are traditionally used to treat various ailments, including inflammation, diabetes, and hypertension, offering significant potential in modern herbal pharmacology.

Family
Thymelaeaceae
Native range
Asia-Tropical
Parts used
Fruit · Leaf
Common names
Not available
Scientific synonyms
Phaleria Papuana · Phaleria Calantha · 3 more

Names and Synonyms

Scientific Names

Accepted name

Phaleria macrocarpa

Synonyms

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Malvales and the family Thymelaeaceae. Ultimately, it is identified by the genus Phaleria.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malvales
Family Thymelaeaceae
Genus Phaleria

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specific geographical distribution spanning across parts of Southeast Asia and Oceania. Within the Indo-China region, its presence can be identified in the Nicobar Islands. Moving further east into the Papuasia region, the species is also found in New Guinea. These distinct locations highlight the plant's ability to thrive in diverse tropical island environments. Consequently, its natural range is characterized by these specific maritime and mainland territories.

Region Area
Indo-China Nicobar Is.
Papuasia New Guinea

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Morphology

The morphology of Phaleria macrocarpa is characterized by its robust growth form, specifically developing into a perennial tree. This botanical structure is defined by its woody nature, possessing a firm, lignified stem that provides the necessary support for its significant height and canopy development.

Growth form :
tree
Woodiness :
woody

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Phaleria macrocarpa has 3 reported plant parts identified across 4 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include fruit, leaf, seed.

Plant parts reported in Phaleria macrocarpa
Plant part Supporting sources Consensus
Fruit 2 supporting sources ★☆☆☆☆
Leaf 1 supporting sources ★☆☆☆☆
Seed 1 supporting sources ★☆☆☆☆

Fruit

  1. Avicenna journal of phytomedicine
  2. Journal of ethnopharmacology

Leaf

  1. TheScientificWorldJournal

Seed

  1. TheScientificWorldJournal

Chemicals

Phaleria macrocarpa has 22 reported phytochemicals identified across 4 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Antioxidants, BAX, Bcl-2, Caspase 3.

Chemicals reported in Phaleria macrocarpa
Chemical Supporting sources Consensus
Flavonoids 2 supporting sources ★☆☆☆☆
Antioxidants 1 supporting sources ★☆☆☆☆
BAX 1 supporting sources ★☆☆☆☆
Bcl-2 1 supporting sources ★☆☆☆☆
Caspase 3 1 supporting sources ★☆☆☆☆
DODECANOIC ACID 1 supporting sources ★☆☆☆☆
Desacetylfevicordin A 1 supporting sources ★☆☆☆☆
ETHYL STEARATE 1 supporting sources ★☆☆☆☆
Gallic acid 1 supporting sources ★☆☆☆☆
Glycosides 1 supporting sources ★☆☆☆☆

Flavonoids

  1. BioMed research international
  2. Journal of ethnopharmacology

Antioxidants

  1. Molecules (Basel, Switzerland)

BAX

  1. TheScientificWorldJournal

Bcl-2

  1. TheScientificWorldJournal

Caspase 3

  1. TheScientificWorldJournal

DODECANOIC ACID

  1. Pharmacognosy reviews

Desacetylfevicordin A

  1. Bioscience, biotechnology, and biochemistry

ETHYL STEARATE

  1. Pharmacognosy reviews

Gallic acid

  1. Pharmacognosy reviews

Glycosides

  1. BioMed research international

Activities

Phaleria macrocarpa has 1 reported activities identified across 4 scientific publications and several other databases. The most consistently reported activities include Chemopreventive.

Activities reported in Phaleria macrocarpa
Activity Supporting sources Consensus
Chemopreventive 1 supporting sources ★☆☆☆☆

Chemopreventive

  1. Journal of ethnopharmacology

Conditions

Phaleria macrocarpa has 23 reported investigations on conditions identified across 4 scientific publications and several other databases. The most consistently reported conditions include cancer, breast cancer, aberrant crypt foci, acne, allergies.

Conditions investigated for Phaleria macrocarpa
Condition Supporting sources Consensus
Cancer 6 supporting sources ★★★☆☆
Breast cancer 3 supporting sources ★★☆☆☆
Aberrant crypt foci 1 supporting sources ★☆☆☆☆
Acne 1 supporting sources ★☆☆☆☆
Allergies 1 supporting sources ★☆☆☆☆
Blood diseases 1 supporting sources ★☆☆☆☆
Blood glucose 1 supporting sources ★☆☆☆☆
Blood pressure 1 supporting sources ★☆☆☆☆
Cholesterol 1 supporting sources ★☆☆☆☆
Colon cancer 1 supporting sources ★☆☆☆☆

Cancer

  1. Pharmacognosy reviews
  2. TheScientificWorldJournal
  3. International journal of oncology
  4. Journal of ethnopharmacology
  5. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
View 1 additional sources
  1. Zeitschrift fur Naturforschung. C, Journal of biosciences

Breast cancer

  1. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
  2. TheScientificWorldJournal
  3. Journal of ethnopharmacology

Aberrant crypt foci

  1. Journal of ethnopharmacology

Acne

  1. Journal of ethnopharmacology

Allergies

  1. Journal of ethnopharmacology

Blood diseases

  1. Journal of ethnopharmacology

Blood glucose

  1. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Blood pressure

  1. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Cholesterol

  1. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Colon cancer

  1. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Preparations

Phaleria macrocarpa has 7 reported preparations identified across 4 scientific publications and several other databases. The most consistently reported preparations include PM aqueous extract, aqueous extract, crude extracts, ethanol extract, ethanol extract of P. macrocarpa fruits.

Preparations reported for Phaleria macrocarpa
Preparation Supporting sources Consensus
Pm aqueous extract 1 supporting sources ★☆☆☆☆
Aqueous extract 1 supporting sources ★☆☆☆☆
Crude extracts 1 supporting sources ★☆☆☆☆
Ethanol extract 1 supporting sources ★☆☆☆☆
Ethanol extract of p. macrocarpa fruits 1 supporting sources ★☆☆☆☆
Extracts 1 supporting sources ★☆☆☆☆
Medicinal plant extract 1 supporting sources ★☆☆☆☆

Pm aqueous extract

  1. Advanced pharmaceutical bulletin

Aqueous extract

  1. Avicenna journal of phytomedicine

Crude extracts

  1. Andrologia

Ethanol extract

  1. TheScientificWorldJournal

Ethanol extract of p. macrocarpa fruits

  1. Journal of ethnopharmacology

Extracts

  1. Journal of food and drug analysis

Medicinal plant extract

  1. Acta medica Indonesiana