Phaleria macrocarpa
Phaleria macrocarpa · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Phaleria macrocarpa, commonly known as Mahkota Dewa, is a medicinal plant highly valued for its diverse therapeutic potential. Various parts of the plant, including the fruit, leaf, and seed, are utilized to create potent medicinal preparations. Researchers frequently employ ethanol extracts, PM aqueous extracts, and standard aqueous extracts to study its biological activities. Scientific investigations have highlighted its significant roles in managing blood glucose, blood pressure, and body weight. Furthermore, the plant demonstrates promising anticancer properties and serves as a powerful source of antioxidants.
- Synonyms
- Phaleria Papuana Var. Wichmannii · Phaleria Papuana · 3 more
- Common names
- Not available
- Family
- Thymelaeaceae
- Distribution
- Not available
- Plant Parts
- Fruit · Leaf
Classification
Common Names
Phaleria macrocarpa is a plant that is widely recognized by several different regional names. In many areas, it is most commonly referred to by the name Mahkota Dewa. Interestingly, it is also known as faléria veľkoplodá in certain contexts. These varying names reflect the plant's diverse botanical identity across different cultures. Understanding these common designations helps enthusiasts identify this unique species more easily.
Sources: Catalogue of Life (COL)
Synonyms
Phaleria macrocarpa is a botanical species known to be associated with several distinct taxonomic synonyms. Historically, it has been identified under the name Drimyspermum macrocarpum in various scientific records. The plant is also linked to the names Phaleria calantha and Phaleria papuana within botanical literature. Furthermore, specific variations such as Phaleria papuana var. wichmannii have been documented in relation to this species. Finally, the name Phaleria wichmannii serves as another synonym closely tied to its classification.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Phaleria macrocarpa is a fascinating botanical specimen that belongs to the kingdom Plantae. Within this vast biological group, it is classified under the class Equisetopsida. Its taxonomic journey continues through the order Malvales, which defines its broader evolutionary placement. Specifically, this plant is a member of the genus Phaleria. Finally, it is nested within the family Thymelaeaceae, completing its complex scientific identity.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malvales |
| Family | Thymelaeaceae |
| Genus | Phaleria |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Phaleria macrocarpa is a plant species primarily found within the diverse ecosystems of the tropical Asian regions. Its natural distribution spans across Indo-China and extends to the Nicobar Islands. Furthermore, the species can be found throughout the Papuasia region, including the island of New Guinea. This widespread presence highlights the plant's adaptability to various humid, tropical environments. Understanding these specific geographic ranges is essential for studying its ecological role in these territories.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Phaleria macrocarpa is characterized by its distinct growth form as a tree.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Phaleria macrocarpa is a medicinal plant traditionally utilized in Indonesian folk medicine to treat various ailments, including cancer. Recent research has specifically investigated its anticancer potential by evaluating the antiproliferative activity of different plant parts against T47D human breast cancer cell lines. Among the various components tested, the leaf extract demonstrated the most potent ability to inhibit cancer cell growth. This effectiveness is driven by the extract's capacity to trigger apoptosis through caspase-3 activation and the regulation of the Bax/Bcl-2 ratio. Consequently, these findings suggest that Phaleria macrocarpa leaves hold significant promise as a potential therapeutic agent for breast cancer.
Compounds
Phaleria macrocarpa, commonly known as Buah Mahkota Dewa, is a plant notable for its significant concentration of bioactive compounds. Scientific research has demonstrated that its fruit contains potent antioxidants, specifically through high levels of phenolics and flavonoids. By utilizing Response Surface Methodology, researchers have successfully optimized extraction conditions to maximize these health-promoting properties. The study revealed that the fruit possesses strong free radical scavenging activity and ferric ion reducing power. Consequently, these antioxidant characteristics make the plant a promising candidate for various medicinal and cosmeceutical applications.
Conditions
Phaleria macrocarpa is a medicinal plant traditionally used to treat a wide variety of diseases. Research indicates that its aqueous extract can improve sexual strength by increasing testosterone levels and libido behavior in male rats. Furthermore, specific extracts such as the leaves demonstrate potent antiproliferative activity that effectively treats T47D human breast cancer cell lines by inducing apoptosis. The plant also possesses valuable medicinal properties, including the ability to treat anti-bacterial infections. These diverse therapeutic applications highlight the significant pharmacological potential of the various parts of the plant.
Preparations
Phaleria macrocarpa is prepared as ethanol extract to evaluate its antioxidant and antiproliferative properties against cancer cell lines. This plant is also prepared as PM aqueous extract to investigate its potential for increasing sperm viability and improving male fertility in rats. Researchers have utilized Phaleria macrocarpa prepared as aqueous extract to study its impact on serum testosterone levels and libido behavior. Furthermore, the plant is prepared as extracts of various ethanol concentrations to facilitate the rapid investigation of α-glucosidase inhibitory activity through FTIR-based fingerprinting. Finally, Phaleria macrocarpa is prepared as a medicinal plant extract that is widely used in traditional medicine for treating various ailments, though it may pose risks such as cholestatic liver injury.
Parts used
Phaleria macrocarpa is a medicinal plant native to Indonesia that contains various bioactive components located in different anatomical structures. Research indicates that the fruit of the plant can be utilized to improve male fertility and provide chemopreventive effects against colorectal cancer. Additionally, the seeds are identified as a significant part of the plant used in comparative studies regarding antiproliferative activities. The leaves have also been highlighted for their potent ability to inhibit the growth of specific breast cancer cell lines through apoptosis. By examining these different parts, scientists continue to uncover the diverse therapeutic potential held within this versatile species.