Phaleria macrocarpa
Phaleria macrocarpa · Accepted scientific name
Scientific literature: Sparse (60 studies) · ★★☆☆☆
Scientifically known as Phaleria macrocarpa, is a medicinal shrub native to Indonesia, commonly referred to as Mahkota Dewa. Renowned for its powerful antioxidant properties, the plant's fruits and leaves are traditionally used to treat various ailments, including inflammation, diabetes, and hypertension, offering significant potential in modern herbal pharmacology.
- Family
- Thymelaeaceae
- Native range
- Asia-Tropical
- Parts used
- Fruit · Leaf
- Common names
- Not available
- Scientific synonyms
- Phaleria Papuana · Phaleria Calantha · 3 more
Names and Synonyms
Scientific Names
Accepted name
Phaleria macrocarpaSynonyms
- Phaleria papuana
- Phaleria calantha
- Drimyspermum macrocarpum
- Phaleria papuana var. wichmannii
- Phaleria wichmannii
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Malvales and the family Thymelaeaceae. Ultimately, it is identified by the genus Phaleria.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malvales |
| Family | Thymelaeaceae |
| Genus | Phaleria |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a specific geographical distribution spanning across parts of Southeast Asia and Oceania. Within the Indo-China region, its presence can be identified in the Nicobar Islands. Moving further east into the Papuasia region, the species is also found in New Guinea. These distinct locations highlight the plant's ability to thrive in diverse tropical island environments. Consequently, its natural range is characterized by these specific maritime and mainland territories.
| Region | Area |
|---|---|
| Indo-China | Nicobar Is. |
| Papuasia | New Guinea |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Morphology
The morphology of Phaleria macrocarpa is characterized by its robust growth form, specifically developing into a perennial tree. This botanical structure is defined by its woody nature, possessing a firm, lignified stem that provides the necessary support for its significant height and canopy development.
- Growth form :
- tree
- Woodiness :
- woody
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Phaleria macrocarpa has 3 reported plant parts identified across 4 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include fruit, leaf, seed.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Fruit | 2 supporting sources | ★☆☆☆☆ |
| Leaf | 1 supporting sources | ★☆☆☆☆ |
| Seed | 1 supporting sources | ★☆☆☆☆ |
Fruit
- Avicenna journal of phytomedicine
- Journal of ethnopharmacology
Leaf
- TheScientificWorldJournal
Seed
- TheScientificWorldJournal
Chemicals
Phaleria macrocarpa has 22 reported phytochemicals identified across 4 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Antioxidants, BAX, Bcl-2, Caspase 3.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Flavonoids | 2 supporting sources | ★☆☆☆☆ |
| Antioxidants | 1 supporting sources | ★☆☆☆☆ |
| BAX | 1 supporting sources | ★☆☆☆☆ |
| Bcl-2 | 1 supporting sources | ★☆☆☆☆ |
| Caspase 3 | 1 supporting sources | ★☆☆☆☆ |
| DODECANOIC ACID | 1 supporting sources | ★☆☆☆☆ |
| Desacetylfevicordin A | 1 supporting sources | ★☆☆☆☆ |
| ETHYL STEARATE | 1 supporting sources | ★☆☆☆☆ |
| Gallic acid | 1 supporting sources | ★☆☆☆☆ |
| Glycosides | 1 supporting sources | ★☆☆☆☆ |
Flavonoids
- BioMed research international
- Journal of ethnopharmacology
Antioxidants
- Molecules (Basel, Switzerland)
BAX
- TheScientificWorldJournal
Bcl-2
- TheScientificWorldJournal
Caspase 3
- TheScientificWorldJournal
DODECANOIC ACID
- Pharmacognosy reviews
Desacetylfevicordin A
- Bioscience, biotechnology, and biochemistry
ETHYL STEARATE
- Pharmacognosy reviews
Gallic acid
- Pharmacognosy reviews
Glycosides
- BioMed research international
Activities
Phaleria macrocarpa has 1 reported activities identified across 4 scientific publications and several other databases. The most consistently reported activities include Chemopreventive.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Chemopreventive | 1 supporting sources | ★☆☆☆☆ |
Chemopreventive
- Journal of ethnopharmacology
Conditions
Phaleria macrocarpa has 23 reported investigations on conditions identified across 4 scientific publications and several other databases. The most consistently reported conditions include cancer, breast cancer, aberrant crypt foci, acne, allergies.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Cancer | 6 supporting sources | ★★★☆☆ |
| Breast cancer | 3 supporting sources | ★★☆☆☆ |
| Aberrant crypt foci | 1 supporting sources | ★☆☆☆☆ |
| Acne | 1 supporting sources | ★☆☆☆☆ |
| Allergies | 1 supporting sources | ★☆☆☆☆ |
| Blood diseases | 1 supporting sources | ★☆☆☆☆ |
| Blood glucose | 1 supporting sources | ★☆☆☆☆ |
| Blood pressure | 1 supporting sources | ★☆☆☆☆ |
| Cholesterol | 1 supporting sources | ★☆☆☆☆ |
| Colon cancer | 1 supporting sources | ★☆☆☆☆ |
Cancer
- Pharmacognosy reviews
- TheScientificWorldJournal
- International journal of oncology
- Journal of ethnopharmacology
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
View 1 additional sources
- Zeitschrift fur Naturforschung. C, Journal of biosciences
Breast cancer
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
- TheScientificWorldJournal
- Journal of ethnopharmacology
Aberrant crypt foci
- Journal of ethnopharmacology
Acne
- Journal of ethnopharmacology
Allergies
- Journal of ethnopharmacology
Blood diseases
- Journal of ethnopharmacology
Blood glucose
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Blood pressure
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Cholesterol
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Colon cancer
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Preparations
Phaleria macrocarpa has 7 reported preparations identified across 4 scientific publications and several other databases. The most consistently reported preparations include PM aqueous extract, aqueous extract, crude extracts, ethanol extract, ethanol extract of P. macrocarpa fruits.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Pm aqueous extract | 1 supporting sources | ★☆☆☆☆ |
| Aqueous extract | 1 supporting sources | ★☆☆☆☆ |
| Crude extracts | 1 supporting sources | ★☆☆☆☆ |
| Ethanol extract | 1 supporting sources | ★☆☆☆☆ |
| Ethanol extract of p. macrocarpa fruits | 1 supporting sources | ★☆☆☆☆ |
| Extracts | 1 supporting sources | ★☆☆☆☆ |
| Medicinal plant extract | 1 supporting sources | ★☆☆☆☆ |
Pm aqueous extract
- Advanced pharmaceutical bulletin
Aqueous extract
- Avicenna journal of phytomedicine
Crude extracts
- Andrologia
Ethanol extract
- TheScientificWorldJournal
Ethanol extract of p. macrocarpa fruits
- Journal of ethnopharmacology
Extracts
- Journal of food and drug analysis
Medicinal plant extract
- Acta medica Indonesiana