Patrinia scabra
Patrinia scabra · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Patrinia scabra is a medicinal plant known for its significant therapeutic potential in traditional practices. The roots of this species serve as the primary part used for various medicinal preparations. Within these roots, bioactive compounds such as isopatriscabrol, patriscabrol, polysaccharides, and saponins play a crucial role in its biological activity. Research has highlighted the plant's ability to influence inflammatory conditions, specifically regarding the modulation of IL-6. Consequently, these chemical properties contribute to the plant's recognized effectiveness as an analgesic agent.
- Synonyms
- Patrinia Rupestris Subsp. Scabra · Fedia Scabra
- Common names
- Not available
- Family
- Caprifoliaceae
- Distribution
- Not available
- Plant Parts
- Root
Classification
Common Names
Patrinia scabra is a distinctive plant recognized by several different common names depending on the linguistic and regional context. In certain areas, it is known as モウコオミナエシ, reflecting its specific botanical identity. It is also frequently referred to by the name 墓头回 in various traditional settings. Depending on the characters used, you may encounter its name written as 糙叶败酱, 糙叶败酱(粗叶败酱）, or the traditional version 糙葉敗醬. These various designations highlight the plant's widespread recognition across different cultural and linguistic landscapes.
Sources: Catalogue of Life (COL)
Synonyms
Patrinia scabra is a plant species that is frequently identified by several different botanical names in scientific literature. It is recognized by the synonym Fedia scabra, which may appear in older taxonomic records. Additionally, this plant is classified under the synonym Patrinia rupestris subsp. scabra depending on the specific botanical framework used. Understanding these various designations is essential for researchers tracking the plant's distribution and genetic lineage. Navigating these nomenclatural relationships ensures accuracy when studying this particular taxon.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Patrinia scabra is a distinct biological entity that belongs to the kingdom Plantae. Within this vast kingdom, the species is classified under the class Equisetopsida. It further falls into the order Dipsacales, showcasing its specific evolutionary lineage. As a member of the Caprifoliaceae family, it shares traits with a diverse group of flowering plants. Ultimately, this plant is defined by its placement within the genus Patrinia.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Dipsacales |
| Family | Caprifoliaceae |
| Genus | Patrinia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Patrinia scabra is a plant native to the diverse landscapes of the Asia-Temperate region. Its natural distribution spans significant portions of China, including the North-Central territories. The species can also be found thriving throughout the Southeast regions of the country. Additionally, its presence extends into the northern reaches of Inner Mongolia. Finally, the plant is well-established within the Manchuria area, showcasing a broad geographic range.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Patrinia scabra is characterized by its distinct herbaceous growth form. This plant remains entirely self-supporting as it develops within its natural habitat.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Patrinia scabra Bunge is a well-known herbal medicine recognized for its significant therapeutic potential in treating inflammatory diseases. Research indicates that the plant contains a high concentration of iridoid glycosides, which play a crucial role in its medicinal efficacy. Through advanced ultrasonic-microwave synergistic extraction, scientists have successfully optimized the recovery of these vital compounds. Pharmacological studies involving various animal models have confirmed that the plant possesses potent analgesic activity. Specifically, the ethanol elution fractions of the extract have been shown to effectively relieve pain both centrally and peripherally.
Compounds
Patrinia scabra is a well-known herbal medicine recognized for its significant analgesic and anti-inflammatory properties. A key component contributing to these medicinal effects is the presence of iridoids within the plant. Detailed investigations into the roots of this species have led to the identification of specific iridolactones. Specifically, the plant contains the compounds patriscabrol and isopatriscabrol. These chemical constituents highlight the complex biological profile that makes the plant so effective in traditional treatments.
Conditions
Patrinia scabra, specifically through its active compound patriscabrin F, effectively treats LPS-induced inflammation by modulating key signaling pathways. This plant works to treat NF-κB activation by decreasing p65 nuclear translocation and inhibiting essential phosphorylation processes. It also treats AP-1 activity by inhibiting c-Fos phosphorylation within macrophages. Furthermore, the plant treats IL-6 by downregulating its production at the transcriptional level. Finally, Patrinia scabra treats NO production by inhibiting the effects of lipopolysaccharide-induced nitric oxide synthase.
Preparations
Patrinia scabra is prepared as roots to facilitate the extraction of specific chemical compounds. The investigation of these roots led to the identification of two new iridolactones named patriscabrol and isopatriscabrol. Researchers utilized extensive NMR spectra analysis and X-ray crystallography to establish the structures found within the root material. Furthermore, four monoglucosides of each iridolactone were isolated from the processed roots. The study also identified an apioside of glucosidic patriscabrol derived from this same root source.
Parts used
Patrinia scabra is a medicinal herb widely utilized throughout Asia for its various therapeutic properties. Scientific investigations have specifically focused on the plant's roots, which serve as a rich source of bioactive compounds. Researchers have successfully isolated unique iridoids, such as patriscabrol and the potent patriscabrin F, directly from these root structures. Specifically, patriscabrin F has demonstrated a remarkable ability to attenuate inflammation by downregulating key signaling pathways in macrophages. Consequently, the chemical constituents found within the roots of Patrinia scabra hold significant promise for future anti-inflammatory pharmacological applications.