Patrinia heterophylla
Patrinia heterophylla · Accepted scientific name
Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆
Patrinia heterophylla is a botanical species known for its significant presence in traditional medicinal applications. The plant's therapeutic potential is largely attributed to its rich chemical profile, which includes key compounds such as iridoids and flavonols. Scientific investigations frequently focus on the medicinal properties of the rhizome and root through various preparations like methanol extract, water extract, and PHW. Research suggests these components may play a role in addressing diverse health conditions, including hepatitis, abscesses, and certain cancers such as colon and colorectal cancer. Consequently, this plant remains a subject of intense interest for its complex pharmacological capabilities.
- Synonyms
- Patrinia Angustifolia · Patrinia Heterophylla Subsp. Angustifolia · 2 more
- Common names
- Not available
- Family
- Caprifoliaceae
- Distribution
- Not available
- Plant Parts
- Rhizome · Root
Classification
Common Names
Patrinia heterophylla is a botanical species known by a diverse array of regional and linguistic identifiers. In certain contexts, it is referred to by the common name kiinankeltavirma. Its identity is also established in Japan through the name ホクシオミナエシ. Within Chinese nomenclature, the plant is frequently called 墓回頭 or 墓头回. Furthermore, it is recognized by the descriptive title 墓头回(异叶败酱), illustrating the many ways this single species is categorized across different cultures.
Sources: Catalogue of Life (COL)
Synonyms
Patrinia heterophylla is a plant species characterized by a complex history of botanical nomenclature. Within taxonomic records, it is frequently associated with several synonyms, including the names Fedia angustifolia and Fedia heterophylla. The plant is also identified in literature as Patrinia angustifolia to distinguish specific variations. Furthermore, it encompasses the subspecies Patrinia heterophylla subsp. angustifolia within its classification. Understanding these diverse naming conventions is essential for accurate identification in botanical studies.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Patrinia heterophylla belongs to the vast kingdom Plantae, representing a diverse branch of the natural world. Within this kingdom, the species is classified under the class Equisetopsida. It further falls into the order Dipsacales, which helps define its botanical characteristics. As a member of the genus Patrinia, it possesses unique traits specific to its lineage. Finally, this plant is nested within the family Caprifoliaceae, completing its formal taxonomic identity.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Dipsacales |
| Family | Caprifoliaceae |
| Genus | Patrinia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Patrinia heterophylla is a notable species found throughout the diverse landscapes of temperate Asia. Its geographical presence is most significant within China, where it spans several distinct regions. Specifically, the plant thrives in the North-Central, South-Central, and Southeast territories of the country. Additionally, its natural habitat extends into the northern reaches of Inner Mongolia and the Manchuria region. This broad distribution highlights the plant's ability to adapt to varying climates across the Asian continent.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Patrinia heterophylla is a self-supporting herb characterized by its distinct growth form. This botanical structure allows the plant to stand upright and thrive within its natural habitat.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Compounds
Patrinia heterophylla serves as a vital medicinal plant used in the traditional treatment of colorectal cancer. Recent network pharmacology analysis has identified several bioactive compounds within its water extract that interact with key cancer-related targets. Among these identified components, asperglaucide stands out as a significant chemical constituent present in the plant. Experimental validation demonstrated that asperglaucide specifically exerts an anti-migratory effect on HCT116 colon cancer cells. These findings highlight the importance of this specific relationship in understanding how the plant may combat cancer progression.
Conditions
Patrinia heterophylla serves as a medicinal resource for treating colorectal cancer (CRC) by targeting key signaling pathways like ErbB. This plant also demonstrates anti-inflammatory capabilities by treating LPS-stimulated BV-2 cells. Specifically, its active compounds work to treat NO production, which helps inhibit inflammatory responses in biological models. Furthermore, traditional medicinal uses of the plant include treating abscesses. These diverse biological activities collectively support the plant's broader potential in anti-cancer applications.
Preparations
Patrinia heterophylla is prepared as PHW to investigate its potential bioactivities against colorectal cancer cells. This specific plant species is also prepared as a water extract for phytochemical profiling using UHPLC-MS. Furthermore, Patrinia heterophylla is prepared as a methanol extract from its rhizomes and roots to facilitate the isolation of iridoids. These different preparation methods allow researchers to study various bioactive compounds, such as asperglaucide in water extracts or novel iridoids in methanol extracts. Through these specific preparations, the medicinal properties and underlying mechanistic pathways of the plant can be effectively validated.
Parts used
Patrinia heterophylla serves as a significant subject for phytochemical investigations due to its bioactive potential. Researchers have focused their extraction efforts on specific anatomical components of the plant to isolate valuable compounds. Specifically, the methanol extract is derived from both the rhizome and the root of the species. These parts contain unique iridoids that demonstrate promising anti-inflammatory activities in various biological models. By studying these specific structures, scientists can better understand the plant's medicinal properties and therapeutic mechanisms.