Ochrosia acuminata

Ochrosia acuminata · Accepted scientific name

Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆

Ochrosia acuminata is a notable botanical species known for its unique phytochemical profile. Researchers have identified significant bioactive compounds within the plant, including 9-Methoxyellipticine, Polyneuridine-N-oxide, and ellipticine. These chemical constituents are primarily concentrated within the root system of the plant. Scientific interest often focuses on the medicinal potential derived from various preparations of these roots. Consequently, studying this plant provides valuable insights into the complex relationship between its chemical makeup and biological activity.

Quick facts
Synonyms
Not available
Common names
Not available
Family
Apocynaceae
Distribution
Not available
Plant Parts
Root

Classification

Taxonomy

Ochrosia acuminata is a distinct member of the kingdom Plantae. This species is classified under the class Equisetopsida and belongs to the order Gentianales. Within this botanical framework, it is categorized under the family Apocynaceae. Furthermore, it is identified as a part of the specific genus Ochrosia. Understanding these taxonomic relationships helps clarify the plant's unique place in the natural world.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Gentianales
Family Apocynaceae
Genus Ochrosia

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Ochrosia acuminata is a distinctive plant species primarily found within the tropical regions of Asia. Its geographic reach is concentrated across the Malesia botanical zone, reflecting its specialized ecological needs. Within this expansive area, the species holds a notable presence on the island of Sulawesi. This specific distribution pattern highlights the unique environmental conditions required for its survival and growth. Understanding these regional connections provides valuable insight into the biodiversity of the Indonesian archipelago.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Morphology

Ochrosia acuminata is characterized by its distinctive growth form as a sturdy tree. This species is naturally self-supporting, allowing it to maintain its structure and height within its environment.

Sources: Global Inventory of Floras and Traits (GIFT)

Biological Activities

Compounds

Ochrosia acuminata serves as a significant source of diverse indole alkaloids found within its roots. Research conducted in Savu, Indonesia, has identified several key chemical constituents within this plant species. Specifically, the plant contains polyneuridine-N-oxide, which was isolated alongside other known alkaloids. Furthermore, the presence of 9-methoxyellipticine and ellipticine has been confirmed through structural elucidation. These specific compounds are particularly noteworthy due to their identified antitumor activities.

Conditions

Ochrosia acuminata contains specific indole alkaloids that contribute to its medicinal potential. The roots of this plant yield compounds such as 9-methoxyellipticine and ellipticine. These particular alkaloids are directly responsible for the antitumor activities observed within the extract. Through chemical analysis, researchers identified these substances as the key drivers of its anticancer properties. Consequently, the plant serves as a significant source for developing targeted antitumor treatments.

Preparations

Ochrosia acuminata is prepared as roots to facilitate the isolation of various indole alkaloids. Researchers collected these specific root samples from the Savu region in Indonesia. Through this preparation, new compounds such as polyneuridine-N-oxide and 17-hydroxy-10-methoxy-yohimbane were successfully identified. The resulting root extracts also contained ellipticine and 9-methoxyellipticine, which are notable for their antitumor activities. Consequently, the root material serves as a vital source for studying these bioactive chemical structures.

Parts used

Ochrosia acuminata serves as a significant source of diverse chemical compounds found within its biological structure. Specifically, research has focused on the roots of this plant to isolate unique indole alkaloids. During studies conducted in Savu, Indonesia, scientists successfully identified two new alkaloids alongside several known variants. Among these findings, compounds such as 9-methoxyellipticine and ellipticine were highlighted for their potential antitumor activities. These results demonstrate how the root system of the species holds valuable medicinal properties for future pharmacological development.