Nitraria tangutorum

What's the taxonomical classification of Nitraria tangutorum?

Nitraria tangutorum belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is situated in the class Equisetopsida and the subclass Magnoliidae. Its taxonomic progression continues through the order Sapindales, leading to its placement in the family Nitrariaceae. Ultimately, the plant is identified by the genus Nitraria and is specifically designated as the species tangutorum.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Sapindales
Family Nitrariaceae
Genus Nitraria
Species tangutorum
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Nitraria tangutorum has small, simple, alternate leaves that are typically ovate to elliptical in shape with entire or slightly serrated margins. The plant develops into a woody shrub or small tree characterized by slender, brownish branches. Its reproductive structures consist of small, inconspicuous flowers that eventually produce fleshy, drupe-like fruits. These fruits are often reddish or yellowish when ripe and contain a single hard seed. The overall foliage displays a dense arrangement that contributes to its compact growth habit.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the arid and semi-arid regions of Northwest China, specifically spanning parts of Xinjiang, Gansu, Ningxia, and Inner Mongolia. It thrives primarily in desert environments and sandy river valleys where soil moisture is limited. The species is also found across certain parts of Central Asia, extending into territories like Kazakhstan and Uzbekistan. Due to its hardy nature, it occupies various ecological niches within these dry landscapes. Its distribution is closely tied to specific climatic conditions that favor drought-tolerant vegetation.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant Nitraria tangutorum thrives in the arid, saline-alkali soils of northwestern China where it requires full sunlight and well-draining ground to grow effectively.

Cultivation begins with planting seeds or cuttings during the spring to take advantage of rising temperatures. Because it is highly drought-tolerant, this species can be established in harsh environments with minimal supplemental irrigation once the root system is mature. Regular pruning is often necessary to maintain a manageable size and to promote the development of dense foliage.

Once established, the plant serves as a vital tool for soil stabilization and desertification control in fragile ecosystems.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Nitraria tangutorum provides medicinal value through its berries, fruit, pericarp, phloem, and root. The edible fruit contains the berries which are often utilized in traditional preparations. Within the fruit, the pericarp serves a specific role in the plant's therapeutic application. The phloem is also harvested to extract essential compounds for treatment. Additionally, the root is processed to harness its unique medicinal properties.

According to a study published by "BMC plant biology", the berries of Nitraria tangutorum Bobr. are used for providing edible and medicinal purposes. The research focused on the fruit coloration of this desert shrub by investigating secondary metabolic and molecular mechanisms. During the mature and transition stages, 122 and 104 flavonoid metabolites were found to be differentially expressed. Specifically, two cyanidin derivatives and one pelargonidin derivative were identified only in the NT phenotype. The study also noted that the enzymatic activity of UFGT was five-fold higher in RT than in YT. These findings provide a theoretical basis for developing new strategies to obtain bioactive compounds from the fruits of Nitraria tangutorum.

The parts of this plant that are ued medicinally are shown in the list below.

  • berries
  • fruit
  • pericarp
  • phloem
  • root
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant Nitraria tangutorum has been utilized in Tibetan Medicine as a therapeutic agent to treat various inflammatory conditions and skin ailments. Practitioners in these traditional systems often employ the plant's components to address issues related to heat and blood circulation. Historical applications frequently involve using the processed parts of the shrub to formulate topical treatments or internal remedies. The medicinal value is derived from its specific chemical properties which are believed to balance bodily energies according to traditional diagnostic frameworks. These long-standing practices highlight the plant's importance in regional ethnobotanical knowledge.

According to a study published by "Journal of ethnopharmacology", the fruits of Nitraria tangutorum Bobr. are a traditional medicinal food of Tibetans. These fruits have been used to alleviate fatigue caused by oxygen deficiency for thousands of years. The plant was collected from Haixi national municipality of Mongol and Tibetan at N 36.32°, E98.11° and an altitude of 3100 m in Qinghai, China. When polysaccharides (NTWP) were orally administered to mice at doses of 50, 100 and 200 mg/kg once daily for 15 days, they demonstrated anti-fatigue activity. In the 200mg/kg group, the spleen indices were increased. NTWP showed better effects than other polysaccharides at the same dosage in inhibiting fatigue indicators.

The hystorical systems that uses this plant are shown in the list below.

  • Tibetan Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Nitraria tangutorum?

This plant has demonstrated significant pharmacological activities including anti-inflammatory, anti-tumor, antioxidant, hypoglycemic, and liver protection properties. Its antioxidant capacity helps neutralize free radicals, which reduces oxidative stress throughout the body. The plant also shows potential in inhibiting tumor growth and suppressing inflammatory responses in various biological models. Furthermore, its hypoglycemic effects assist in regulating blood glucose levels, making it relevant for metabolic studies. Finally, the medicinal components contribute to liver protection by mitigating damage caused by toxins or disease.

According to a study published by "PeerJ", Nitraria tangutorum contains various compounds including flavonoids, alkaloids, phenolic acids and polysaccharides. These compounds provide beneficial bioactivities such as antioxidant, anti-inflammatory, anti-tumor, anti-fatigue, liver protection, neuroprotection, cardiovascular protection, lowering blood lipid, regulating blood sugar level and immunoregulation. The fruits of the plant also contain vitamin C, amino acids, minerals and microelements. In folk medicine, it is used to treat diseases of the spleen and stomach, abnormal menstruation, indigestion, and hyperlipidemia. This plant possesses remarkable economic and medicinal values due to its medicinal and edible homology.

The primary pharmacological activities of this plant are shown in the list below.

  • a-glucosidase inhibitory effects
  • anti-inflammatory
  • anti-tumor
  • antioxidant
  • hypoglycemic
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains medicinal compounds including tangutorid LI-III, coumaroyl glucoside, beta-carboline alkaloids, and various flavonoids. These diverse chemical constituents contribute to the complex pharmacological profile of Nitraria tangutorum. The presence of specific alkaloids plays a significant role in its traditional therapeutic applications. Additionally, the flavonoids found within the plant are known for their biological activities. These combined phytochemicals work together to define the plant's medicinal properties.

According to a study published by "Food chemistry", Nitraria tangutorum Bobr. fruit contains three novel coumaroyl glucoside beta-carboline alkaloids tentatively identified as tangutorid LI-III. Research into the fruit's medicinal compounds identified depsides, specifically dihydroxybenzoyl-trihydroxyphenylmethylacetate 14, which demonstrated strong sucrase and maltase inhibitory activities along with noteworthy insulin resistance ameliorative effects. Additionally, the cyclic dipeptide cyclo (tyr-tyr) 10 was demonstrated to have a significant insulin resistance improvement effect. These findings regarding the chemical components and bioactivities of Nitraria tangutorum Bobr. help enrich the structural types of beta-carboline alkaloids found in fruits.

The primary medicinal compounds of this plant are shown in the list below.

  • tangutorid LI-III
  • β-carboline alkaloids
  • coumaroyl glucoside β-carboline alkaloids
  • alkaloids
  • flavonoids
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for managing diabetes, abnormal blood sugar levels, hyperlipidemia, inflammation, and liver damage. Its bioactive compounds assist in regulating glucose metabolism to stabilize blood sugar in diabetic patients. The plant also plays a significant role in lowering lipid levels to combat hyperlipidemia. Additionally, it possesses potent properties that reduce systemic inflammation throughout the body. These medicinal effects extend to the hepatic system, where it helps mitigate various forms of liver damage.

According to a study published by "PeerJ", Nitraria tangutorum contains various compounds such as flavonoids, alkaloids, phenolic acids and polysaccharides. These compounds provide beneficial bioactivities including antioxidant, anti-inflammatory, anti-tumor, anti-fatigue, liver protection, neuroprotection, cardiovascular protection, lowering blood lipid, regulating blood sugar level and immunoregulation. The fruits of the plant also contain vitamin C, amino acids, minerals and microelements. In folk medicine, the plant has been traditionally used to treat diseases of the spleen and stomach, abnormal menstruation, indigestion, and hyperlipidemia.

The main health conditions this plant is used for are shown in the list below.

  • abnormal blood sugar level
  • diabetes
  • hyperlipidemia
  • inflammation
  • liver damage
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is used to create medicinal herbal preparations known as NTWP, which are derived from the fruit of Nitraria tangutorum to treat various ailments. These preparations are often utilized in traditional medicine to manage inflammation and support digestive health. The chemical components within the plant extracts provide bioactive properties that contribute to its therapeutic efficacy. Researchers are currently studying these formulations to better understand their specific pharmacological mechanisms. Through controlled processing, the plant material is transformed into standardized medicinal products for clinical application.

According to a study published by "Journal of ethnopharmacology", the fruits of Nitraria tangutorum Bobr. are traditional medicinal food of Tibetans used for thousands of years to alleviate fatigue caused by oxygen deficiency. Polysaccharides from these fruits, referred to as NTWP, were collected from an altitude of 3100 m at N 36.32°, E98.11° in Haixi national municipality of Mongol and Tibetan, Qinghai, China. These polysaccharides were orally administered to mice at doses of 50, 100 and 200 mg/kg once daily for 15 days. The NTWP demonstrated anti-fatigue activity at lower doses compared to other studied polysaccharides and inhibited the reduction of glucose, superoxide dismutase, and glutathione peroxidase, as well as the increase of creatine phosphokinase, lactic dehydrogenase, blood urea nitrogen, triglyceride, and malondialdehyde. Additionally, the spleen indices were increased in the NTWP group at 200 mg/kg.

The main herbal preparations of this plant are shown in the list below.

  • NTWP
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause several adverse health side effects including dizziness, dyspepsia, neurasthenia, stomach syndrome, and weakness of the spleen. Individuals consuming this species may experience digestive complications such as dyspepsia or more severe stomach syndrome. The neurological impact can manifest as neurasthenia or bouts of dizziness. Furthermore, it may lead to systemic issues like a noticeable weakness of the spleen. These physiological reactions suggest that the plant should be used with caution.

According to a study published by "Food & function", the Nitraria tangutorum Bobr. fruit grows at an altitude of over 3000 m in the Tibetan Plateau and has been used as a native medicinal food for thousands of years to treat weakness of the spleen, stomach syndrome, dyspepsia, neurasthenia, and dizziness. An anthocyanin fraction named NJBAE, obtained from industrial juice by-products, was found to be composed of 16 anthocyanins derived from 6 anthocyanidins. This NJBAE fraction demonstrated an appreciable cardioprotective effect on doxorubicin-induced injured H9c2 cardiomyocytes. The mechanism involves scavenging ROS, restricting further generation of ROS, and promoting key antioxidase activity to mediate caspase-dependent cell death pathways. Consequently, the plant has potential for preventing and treating cardiovascular disease.

The main side effects this plant can have are shown in the list below.

  • dizziness
  • dyspepsia
  • neurasthenia
  • stomach syndrome
  • weakness of the spleen
Evidence Level: ★★★☆☆

What herbs are paired with Nitraria tangutorum?

This plant Nitraria tangutorum is traditionally paired with herbs such as Glycyrrhiza glabra, Scutellaria baicalensis, and Coptis chinensis to enhance its medicinal efficacy in treating inflammatory conditions.

These combinations are frequently utilized in traditional formulas to balance the plant's bitter properties and address heat-related ailments. When combined with Glycyrrhiza glabra, the mixture helps to harmonize the various active compounds and mitigate potential gastric irritation. The addition of Scutellaria and Coptis intensifies the cooling effect, making the pairing more effective for clearing toxins from the body.

Such herbal synergies are carefully measured to ensure the therapeutic impact is optimized for specific patient needs.

Evidence Level: ★☆☆☆☆