Black-cumin
Nigella sativa · Accepted scientific name
Scientific literature: Very Extensive (1887 studies) · ★★★★★
Black-cumin, scientifically known as Nigella sativa, is a versatile medicinal plant celebrated for its profound therapeutic properties. Often referred to as "black seed," this nutrient-dense spice contains thymoquinone, a powerful compound known for its antioxidant, anti-inflammatory, and antimicrobial effects, making it a cornerstone in traditional and modern wellness.
- Family
- Ranunculaceae
- Native range
- Europe
- Parts used
- Seed · Leaf
- Common names
- Black-Cumin · Roman-Coriander · 8 more
- Scientific synonyms
- Not available
Names and Synonyms
Common Names
- Black-cumin
- Roman-coriander
- black-caraway
- fennel-flower
- nigella
- nutmeg-flower
- Black Cumin
- Common fennel flower
- black caraway
- black onion seed
Scientific Names
Accepted name
Nigella sativaRegional and Traditional Names
Spanish:
- Nigella truncata
- Nigella cretica
- Kalonji
- Neguilla hortense
- Toda especia
- ajenuz
- arañuel
- Neguilla
German:
- Echter Schwarzkümmel
- Schwarzer Kümmel
- Schwarzkümmel
- Saat-Schwarzkümmel
- Echter Schwarzkümmel
French:
- Nigelle cultivée
- Cumin noir
- Nigelle cultivee
- nigelle de Crète
- toute épice
- Nigelle cultivée
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and the class Equisetopsida. As a member of the subclass Magnoliidae and the order Ranunculales, it is further categorized under the family Ranunculaceae. Finally, its specific taxonomic placement is defined by the genus Nigella.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Ranunculales |
| Family | Ranunculaceae |
| Genus | Nigella |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a diverse geographical distribution across several key regions of the European continent. In Middle Europe, its presence is noted within the territories of Germany as well as the Czechia-Slovakia region. Moving toward the Mediterranean, it can be found growing throughout Southwestern Europe, specifically in France. The species also extends into Southeastern Europe, where it is established in Bulgaria. Finally, its range continues further south into the coastal and inland areas of Greece.
| Region | Area |
|---|---|
| Middle Europe | Czechia-Slovakia |
| Middle Europe | Germany |
| Southwestern Europe | France |
| Southeastern Europe | Bulgaria |
| Southeastern Europe | Greece |
| Southeastern Europe | Italy |
| Southeastern Europe | Romania |
| Southeastern Europe | Türkiye-in-Europe |
| Southeastern Europe | NW. Balkan Pen. |
| Eastern Europe | Belarus |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Nigella sativa is characterized by its ability to colonize diverse environments, frequently establishing itself within anthropogenic landscapes such as cropfields and parks. It thrives in these modified habitats where soil conditions and human activity may provide favorable germination niches. Furthermore, the species exhibits a significant vertical distribution, with its ecological presence recorded at a mean elevation of 1800 m AMSL, indicating an adaptability to specific altitudinal gradients and the atmospheric conditions associated with such mid-to-high altitude ranges.
- Elevational range mean:
- 1800 m AMSL
- Habitat :
- cropfields,parks
Life history
The life history of Nigella sativa is characterized by an annual lifecycle, meaning the plant completes its entire developmental process—from germination to seed production—within a single growing season. As a therophyte, it survives the unfavorable periods of its environment by completing its life cycle rapidly and persisting through seed dormancy rather than maintaining vegetative structures. This life form strategy allows it to efficiently utilize seasonal moisture and nutrients to reach maturity before the onset of harsh conditions, ensuring the continuity of the species through the dispersal of its seeds.
- Life form :
- therophyte
- Lifecycle :
- annual
Morphology
The morphology of Nigella sativa is characterized by its growth form as a non-woody herb, specifically classified as a forb. The plant is a self-supporting organism that does not function as a climber or a liana, maintaining an independent existence as it is neither a parasite nor an epiphyte, growing instead in a terrestrial habitat. In terms of stature, it is a relatively low-growing species with a plant height that typically ranges from a minimum of 0.2 m to a maximum of 0.5 m, resulting in an average height of approximately 0.2825 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Growth form :
- forb
- Parasite :
- independent
- Plant height max:
- 0.5 m
- Plant height mean:
- 0.2825 m
- Plant height min:
- 0.2 m
- Woodiness :
- non-woody
Physiology
The physiology of Nigella sativa is characterized by a C3 photosynthetic pathway, meaning it utilizes the Calvin cycle to fix carbon dioxide through the enzyme Rubisco, which is typical for many herbaceous annuals in the Ranunculaceae family. This metabolic process involves the direct fixation of CO2 into three-carbon compounds, making the plant's carbon assimilation efficiency highly dependent on environmental conditions such as temperature and water availability. Furthermore, Nigella sativa is not a nitrogen fixer; it lacks the specialized symbiotic relationship with rhizobia or other nitrogen-fixing bacteria required to convert atmospheric nitrogen into a usable form, and therefore relies on the uptake of nitrates and ammonium from the soil to satisfy its nutritional requirements for growth and development.
- Nitrogen fixer :
- no
- Photosynthetic pathway :
- C3
Reproduction
The reproductive cycle of Nigella sativa is characterized by a distinct seasonal flowering period that typically begins in June and concludes in August. The plant utilizes biotic pollination syndromes, specifically relying on insects such as bees to facilitate the fertilization process. Once fertilization occurs, the plant develops fruit in the form of a capsule, with a consistent length measuring approximately 1 cm (ranging from a minimum to a maximum of 1 cm). These capsules are dehiscent, meaning they split open to release the seeds. The resulting seeds are quite small, possessing a mean mass of 0.00141 g, with individual seed weights ranging from a minimum of 0.00051 g to a maximum of 0.00231 g. Regarding seed dispersal, the plant employs an unspecialized syndrome alongside anthropochorous dispersal, indicating that while it lacks a highly specialized natural mechanism, human activity plays a significant role in its distribution.
- Dehiscence :
- dehiscent
- Dispersal syndrome :
- unspecialized
- Dispersal syndrome :
- anthropochorous
- Flowering time :
- Jun
- Flowering time :
- Aug
- Fruit length max:
- 1 cm
- Fruit type :
- capsule
- Pollination syndrome :
- insect
- Pollination syndrome :
- bee
- Pollination syndrome :
- biotic
- Seed mass max:
- 0.00231 g
- Seed mass mean:
- 0.00141 g
- Seed mass min:
- 0.00051 g
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Nigella sativa has 2 reported plant parts identified across 72 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include seed, leaf.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Seed | 71 supporting sources | ★★★★★ |
| Leaf | 1 supporting sources | ★☆☆☆☆ |
Seed
- PloS one
- Saudi journal of biological sciences
- Fundamental & clinical pharmacology
- Iranian journal of basic medical sciences
- Journal of endocrinological investigation
View 66 additional sources
- Pakistan journal of biological sciences : PJBS
- International journal of immunopharmacology
- International journal of health sciences
- Infection and drug resistance
- Chemosphere
- Molecules (Basel, Switzerland)
- Immunopharmacology
- Journal of ethnopharmacology
- Asian Pacific journal of tropical biomedicine
- Journal of biomolecular structure & dynamics
- Chemical & pharmaceutical bulletin
- Journal of fish diseases
- Biochimica et biophysica acta
- Scientific reports
- Planta medica
- Journal of parasitic diseases : official organ of the Indian Society for Parasitology
- Pakistan journal of pharmaceutical sciences
- Toxicon : official journal of the International Society on Toxinology
- Pharmacological research
- Acta diabetologica latina
- Indian journal of experimental biology
- Drug research
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Therapie
- Organic letters
- Journal de pharmacie de Belgique
- BMC complementary and alternative medicine
- Food & function
- Journal of food science
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Biomedical chromatography : BMC
- Plants (Basel, Switzerland)
- Current pharmaceutical biotechnology
- Journal of natural products
- Chinese journal of natural medicines
- Acta biologica Hungarica
- Current drug discovery technologies
- Combinatorial chemistry & high throughput screening
- Environmental health insights
- Journal of food biochemistry
- JPMA. The Journal of the Pakistan Medical Association
- Clinical nutrition ESPEN
- Asian Pacific journal of cancer prevention : APJCP
- Metabolic brain disease
- Journal of oleo science
- Avicenna journal of phytomedicine
- BMC microbiology
- Food science and biotechnology
- Drug design, development and therapy
- Indian journal of physiology and pharmacology
- Journal of Ayub Medical College, Abbottabad : JAMC
- Journal of toxicology
- Chemistry & biodiversity
- Lipids in health and disease
- Toxicology and industrial health
- Natural product research
- Physiology international
- Journal of ethnobiology and ethnomedicine
- Complementary therapies in clinical practice
- African journal of traditional, complementary, and alternative medicines : AJTCAM
- Paediatric drugs
- Journal of pharmacy & bioallied sciences
- Inflammopharmacology
- Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
- International immunopharmacology
- International journal of biological macromolecules
Leaf
- Life (Basel, Switzerland)
Chemicals
Nigella sativa has 192 reported phytochemicals identified across 72 scientific publications and several other databases. The most consistently reported chemicals include Thymoquinone, Flavonoids, THYMOL, linoleic acid, oil.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Thymoquinone | 68 supporting sources | ★★★★★ |
| Flavonoids | 12 supporting sources | ★★★★★ |
| THYMOL | 11 supporting sources | ★★★★★ |
| linoleic acid | 10 supporting sources | ★★★★★ |
| oil | 9 supporting sources | ★★★★☆ |
| CARVACROL | 8 supporting sources | ★★★★☆ |
| Saponins | 7 supporting sources | ★★★★☆ |
| Thymohydroquinone | 7 supporting sources | ★★★★☆ |
| Fatty acids | 6 supporting sources | ★★★☆☆ |
| Nigellidine | 6 supporting sources | ★★★☆☆ |
Thymoquinone
- Dr. Duke
- Pharmaceutical biology
- General pharmacology
- Letters in applied microbiology
- Cellular and molecular neurobiology
View 63 additional sources
- Journal of cardiovascular pharmacology
- Advanced pharmaceutical bulletin
- Plants (Basel, Switzerland)
- Evidence-based complementary and alternative medicine : eCAM
- Vascular health and risk management
- European journal of pharmacology
- Molecular cancer research : MCR
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Food science & nutrition
- Asian Pacific journal of tropical biomedicine
- Medicinal chemistry (Shariqah (United Arab Emirates))
- Parasites & vectors
- Avicenna journal of phytomedicine
- Research in pharmaceutical sciences
- Veterinary research forum : an international quarterly journal
- Planta medica
- Journal of chromatographic science
- The American journal of Chinese medicine
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Experimental parasitology
- International journal of nanomedicine
- Journal of ethnopharmacology
- Frontiers in nutrition
- Current aging science
- Journal of pharmacopuncture
- Current drug metabolism
- Molecules (Basel, Switzerland)
- Drug research
- CNS & neurological disorders drug targets
- Iranian journal of basic medical sciences
- Phytochemical analysis : PCA
- Food & function
- International journal of dermatology
- Open life sciences
- Current molecular medicine
- Frontiers in pharmacology
- Current pharmaceutical biotechnology
- Pharmaceutics
- PeerJ
- Yao xue xue bao = Acta pharmaceutica Sinica
- Food technology and biotechnology
- Food chemistry
- Metabolic brain disease
- Toxicology letters
- Drug design, development and therapy
- Journal of burn care & research : official publication of the American Burn Association
- Journal of applied toxicology : JAT
- Journal of tropical medicine
- Chemistry & biodiversity
- Cell biology international
- Current issues in molecular biology
- Anti-cancer agents in medicinal chemistry
- Critical reviews in food science and nutrition
- Phytotherapy research : PTR
- Phytochemistry
- Saudi journal of biological sciences
- Iranian journal of pharmaceutical research : IJPR
- African journal of traditional, complementary, and alternative medicines : AJTCAM
- Journal of oleo science
- Oncology letters
- Biochemistry research international
- Mini reviews in medicinal chemistry
- BMC complementary medicine and therapies
Flavonoids
- Journal of the science of food and agriculture
- Pakistan journal of pharmaceutical sciences
- TheScientificWorldJournal
- Frontiers in bioengineering and biotechnology
- Molecules (Basel, Switzerland)
View 7 additional sources
- Nutrients
- Iranian journal of basic medical sciences
- PeerJ
- Frontiers in pharmacology
- Food chemistry
- Pharmaceutical chemistry journal
- Food science & nutrition
THYMOL
- Dr. Duke
- Phytochemical analysis : PCA
- Foods (Basel, Switzerland)
- Journal of biomolecular structure & dynamics
- Medicinal chemistry (Shariqah (United Arab Emirates))
View 6 additional sources
- Journal of chromatographic science
- The American journal of Chinese medicine
- Journal of pharmacopuncture
- Journal of tropical medicine
- Journal de mycologie medicale
- BMC complementary medicine and therapies
linoleic acid
- Dr. Duke
- Zeitschrift fur Naturforschung. C, Journal of biosciences
- Advanced pharmaceutical bulletin
- Foods (Basel, Switzerland)
- Pakistan journal of pharmaceutical sciences
View 5 additional sources
- Evidence-based complementary and alternative medicine : eCAM
- Biochimica et biophysica acta
- Avicenna journal of phytomedicine
- Frontiers in pharmacology
- Chemistry & biodiversity
oil
- Trials
- Iranian journal of basic medical sciences
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Journal of ethnopharmacology
- Acta biologica Hungarica
View 4 additional sources
- Journal of parasitic diseases : official organ of the Indian Society for Parasitology
- Pakistan journal of pharmaceutical sciences
- Saudi journal of biological sciences
- International immunopharmacology
CARVACROL
- Phytochemical analysis : PCA
- Journal of chromatographic science
- The American journal of Chinese medicine
- Journal of pharmacopuncture
- Journal of tropical medicine
View 3 additional sources
- Journal de mycologie medicale
- Critical reviews in food science and nutrition
- Biochemistry research international
Saponins
- Pakistan journal of pharmaceutical sciences
- TheScientificWorldJournal
- Food science & nutrition
- International journal of dermatology
- Frontiers in pharmacology
View 2 additional sources
- Food chemistry
- Critical reviews in food science and nutrition
Thymohydroquinone
- Dr. Duke
- Journal of biomolecular structure & dynamics
- The American journal of Chinese medicine
- Journal of pharmacopuncture
- Die Pharmazie
View 2 additional sources
- Food technology and biotechnology
- Journal of tropical medicine
Fatty acids
- Vascular health and risk management
- TheScientificWorldJournal
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Evidence-based complementary and alternative medicine : eCAM
- Izvestiia Akademii nauk. Seriia biologicheskaia
View 1 additional sources
- Iranian journal of basic medical sciences
Nigellidine
- Dr. Duke
- Chemistry & biodiversity
- The American journal of Chinese medicine
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Molecules (Basel, Switzerland)
View 1 additional sources
- Journal of tropical medicine
Activities
Nigella sativa has 403 reported activities identified across 72 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antimicrobial, Antidiabetic, Antibacterial.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 54 supporting sources | ★★★★★ |
| Anticancer | 28 supporting sources | ★★★★★ |
| Antimicrobial | 22 supporting sources | ★★★★★ |
| Antidiabetic | 19 supporting sources | ★★★★★ |
| Antibacterial | 17 supporting sources | ★★★★★ |
| Analgesic | 14 supporting sources | ★★★★★ |
| Neuroprotective | 13 supporting sources | ★★★★★ |
| Hepatoprotective | 9 supporting sources | ★★★★☆ |
| Bronchodilator | 8 supporting sources | ★★★★☆ |
| Antiviral | 7 supporting sources | ★★★★☆ |
Antioxidant
- Dr. Duke
- Integrative medicine research
- Current pharmaceutical biotechnology
- The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
- Journal of ovarian research
View 49 additional sources
- BMC complementary and alternative medicine
- Molecules (Basel, Switzerland)
- TheScientificWorldJournal
- Pharmaceutical biology
- Evidence-based complementary and alternative medicine : eCAM
- Food science & nutrition
- Journal of food science
- Parasites & vectors
- Naunyn-Schmiedeberg's archives of pharmacology
- The American journal of Chinese medicine
- BioMed research international
- Journal of traditional and complementary medicine
- International journal of nanomedicine
- Journal of ethnopharmacology
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Journal of pharmacopuncture
- Complementary therapies in clinical practice
- Drug research
- Iranian journal of basic medical sciences
- Biochemistry and biophysics reports
- Comptes rendus biologies
- Food & function
- Animals : an open access journal from MDPI
- International journal of biological macromolecules
- PeerJ
- Journal of food biochemistry
- Food technology and biotechnology
- Nutrients
- Metabolic brain disease
- Avicenna journal of phytomedicine
- Journal of applied toxicology : JAT
- Chemistry & biodiversity
- Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
- Birth defects research
- Current issues in molecular biology
- Frontiers in bioengineering and biotechnology
- Pharmaceuticals (Basel, Switzerland)
- Iranian journal of pharmaceutical research : IJPR
- Dose-response : a publication of International Hormesis Society
- Phytotherapy research : PTR
- Journal of herbal medicine
- Medicina (Kaunas, Lithuania)
- Nutritional neuroscience
- Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
- Oncology letters
- Frontiers in pharmacology
- International journal of molecular sciences
- Andrologia
- BMC complementary medicine and therapies
Anticancer
- Dr. Duke
- Molecular cancer research : MCR
- Molecules (Basel, Switzerland)
- Evidence-based complementary and alternative medicine : eCAM
- Asian Pacific journal of tropical biomedicine
View 23 additional sources
- Journal of food science
- Parasites & vectors
- Naunyn-Schmiedeberg's archives of pharmacology
- The American journal of Chinese medicine
- Frontiers in nutrition
- Frontiers in pharmacology
- Food & function
- International journal of biological macromolecules
- Scientific reports
- Heliyon
- PeerJ
- Drug and chemical toxicology
- Journal of food biochemistry
- Pakistan journal of pharmaceutical sciences
- Advanced pharmaceutical bulletin
- Cell biology international
- Anti-cancer agents in medicinal chemistry
- Frontiers in bioengineering and biotechnology
- Journal of biomolecular structure & dynamics
- Iranian journal of pharmaceutical research : IJPR
- Nutrients
- Journal of herbal medicine
- Biochemical and biophysical research communications
Antimicrobial
- Integrative medicine research
- BMC complementary and alternative medicine
- Evidence-based complementary and alternative medicine : eCAM
- Asian Pacific journal of tropical biomedicine
- Journal of food science
View 17 additional sources
- Naunyn-Schmiedeberg's archives of pharmacology
- The American journal of Chinese medicine
- Journal of ethnopharmacology
- Frontiers in nutrition
- Complementary therapies in clinical practice
- Drug research
- Current medicinal chemistry
- International journal of dermatology
- Drug and chemical toxicology
- Die Pharmazie
- Food chemistry
- BMC microbiology
- Current issues in molecular biology
- Iranian journal of pharmaceutical research : IJPR
- Journal of herbal medicine
- Environmental science and pollution research international
- BMC complementary medicine and therapies
Antidiabetic
- Dr. Duke
- Molecules (Basel, Switzerland)
- Evidence-based complementary and alternative medicine : eCAM
- Food science & nutrition
- Asian Pacific journal of tropical biomedicine
View 14 additional sources
- Journal of food science
- Journal of ethnopharmacology
- Frontiers in nutrition
- BMC complementary and alternative medicine
- Food & function
- International journal of dermatology
- PeerJ
- Journal of food biochemistry
- Frontiers in bioengineering and biotechnology
- Iranian journal of pharmaceutical research : IJPR
- Iranian biomedical journal
- Nutrients
- Journal of herbal medicine
- Medicina (Kaunas, Lithuania)
Antibacterial
- Dr. Duke
- Pakistan journal of pharmaceutical sciences
- Food science & nutrition
- Inflammopharmacology
- BioMed research international
View 12 additional sources
- Frontiers in nutrition
- Journal of ethnopharmacology
- International journal of biological macromolecules
- PeerJ
- Journal of food biochemistry
- Journal of oleo science
- Infection and drug resistance
- Journal of tropical medicine
- Current issues in molecular biology
- Frontiers in bioengineering and biotechnology
- Pharmaceuticals (Basel, Switzerland)
- The American journal of Chinese medicine
Analgesic
- Dr. Duke
- Integrative medicine research
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Asian Pacific journal of tropical biomedicine
- Inflammopharmacology
View 9 additional sources
- Naunyn-Schmiedeberg's archives of pharmacology
- International journal of dermatology
- Chinese journal of natural medicines
- Pakistan journal of pharmaceutical sciences
- Physiology international
- Iranian journal of pharmaceutical research : IJPR
- Complementary therapies in clinical practice
- Journal of herbal medicine
- Phytotherapy research : PTR
Neuroprotective
- Journal of traditional and complementary medicine
- International journal of molecular sciences
- Naunyn-Schmiedeberg's archives of pharmacology
- Pharmacological research
- CNS & neurological disorders drug targets
View 8 additional sources
- BioFactors (Oxford, England)
- Food & function
- Current molecular medicine
- Metabolic brain disease
- Birth defects research
- The American journal of Chinese medicine
- Nutritional neuroscience
- Frontiers in pharmacology
Hepatoprotective
- Dr. Duke
- The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
- Molecules (Basel, Switzerland)
- Pharmacological research
- Journal of pharmacopuncture
View 4 additional sources
- Food & function
- Journal of ethnopharmacology
- Endocrine, metabolic & immune disorders drug targets
- Journal of herbal medicine
Bronchodilator
- Asian Pacific journal of tropical biomedicine
- Naunyn-Schmiedeberg's archives of pharmacology
- International journal of dermatology
- Iranian journal of basic medical sciences
- JPMA. The Journal of the Pakistan Medical Association
View 3 additional sources
- Iranian journal of pharmaceutical research : IJPR
- Journal of herbal medicine
- Journal of pharmacy & bioallied sciences
Antiviral
- Dr. Duke
- Pharmaceutical biology
- Frontiers in pharmacology
- Food science & nutrition
- Saudi journal of biological sciences
View 2 additional sources
- Pharmaceutical chemistry journal
- Journal of tropical medicine
Medicinal Uses
Nigella sativa has 295 reported medicinal uses identified across 72 scientific publications and several other databases. The most consistently reported uses include cancer, oxidative stress, inflammation, COVID-19, hypertension.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| cancer | Current pharmaceutical biotechnology (and other 29 sources) | ★★★★★ |
| oxidative stress | Trials (and other 19 sources) | ★★★★★ |
| inflammation | Trials (and other 17 sources) | ★★★★★ |
| COVID-19 | Pharmaceutical biology (and other 14 sources) | ★★★★★ |
| hypertension | Ibrain (and other 9 sources) | ★★★★☆ |
| Staphylococcus aureus | Pakistan journal of pharmaceutical sciences (and other 8 sources) | ★★★★☆ |
| breast cancer | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (and other 8 sources) | ★★★★☆ |
| diabetes mellitus | Ibrain (and other 8 sources) | ★★★★☆ |
| neurodegenerative diseases | Ibrain (and other 8 sources) | ★★★★☆ |
| asthma | Iranian journal of basic medical sciences (and other 7 sources) | ★★★★☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| seeds | Saudi journal of biological sciences (and other 9 sources) | ★★★★☆ |
| oil | Iranian journal of basic medical sciences (and other 8 sources) | ★★★★☆ |
| Nigella sativa oil | Pakistan journal of biological sciences : PJBS (and other 6 sources) | ★★★☆☆ |
| extracts | Global advances in integrative medicine and health (and other 6 sources) | ★★★☆☆ |
| NS oil | Avicenna journal of phytomedicine (and other 5 sources) | ★★★☆☆ |
| hydro-alcoholic extract | Journal of traditional and complementary medicine (and other 3 sources) | ★★☆☆☆ |
| methanolic extract | Journal of endocrinological investigation (and other 3 sources) | ★★☆☆☆ |
| NSO | International journal of molecular sciences (and other 2 sources) | ★☆☆☆☆ |
| Nigella sativa extract | Pakistan journal of biological sciences : PJBS (and other 2 sources) | ★☆☆☆☆ |
| Nigella sativa seed oil | Biochimica et biophysica acta (and other 2 sources) | ★☆☆☆☆ |