Black-cumin

Nigella sativa · Accepted scientific name

Scientific literature: Very Extensive (1887 studies) · ★★★★★

Black-cumin, scientifically known as Nigella sativa, is a versatile medicinal plant celebrated for its profound therapeutic properties. Often referred to as "black seed," this nutrient-dense spice contains thymoquinone, a powerful compound known for its antioxidant, anti-inflammatory, and antimicrobial effects, making it a cornerstone in traditional and modern wellness.

Family
Ranunculaceae
Native range
Europe
Parts used
Seed · Leaf
Common names
Black-Cumin · Roman-Coriander · 8 more
Scientific synonyms
Not available

Names and Synonyms

Common Names

Scientific Names

Accepted name

Nigella sativa

Regional and Traditional Names

Spanish:

  • Nigella truncata
  • Nigella cretica
  • Kalonji
  • Neguilla hortense
  • Toda especia
  • ajenuz
  • arañuel
  • Neguilla

German:

  • Echter Schwarzkümmel
  • Schwarzer Kümmel
  • Schwarzkümmel
  • Saat-Schwarzkümmel
  • Echter Schwarzkümmel

French:

  • Nigelle cultivée
  • Cumin noir
  • Nigelle cultivee
  • nigelle de Crète
  • toute épice
  • Nigelle cultivée

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified within the phylum Streptophyta and the class Equisetopsida. As a member of the subclass Magnoliidae and the order Ranunculales, it is further categorized under the family Ranunculaceae. Finally, its specific taxonomic placement is defined by the genus Nigella.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Ranunculales
Family Ranunculaceae
Genus Nigella

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a diverse geographical distribution across several key regions of the European continent. In Middle Europe, its presence is noted within the territories of Germany as well as the Czechia-Slovakia region. Moving toward the Mediterranean, it can be found growing throughout Southwestern Europe, specifically in France. The species also extends into Southeastern Europe, where it is established in Bulgaria. Finally, its range continues further south into the coastal and inland areas of Greece.

Region Area
Middle Europe Czechia-Slovakia
Middle Europe Germany
Southwestern Europe France
Southeastern Europe Bulgaria
Southeastern Europe Greece
Southeastern Europe Italy
Southeastern Europe Romania
Southeastern Europe Türkiye-in-Europe
Southeastern Europe NW. Balkan Pen.
Eastern Europe Belarus

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Nigella sativa is characterized by its ability to colonize diverse environments, frequently establishing itself within anthropogenic landscapes such as cropfields and parks. It thrives in these modified habitats where soil conditions and human activity may provide favorable germination niches. Furthermore, the species exhibits a significant vertical distribution, with its ecological presence recorded at a mean elevation of 1800 m AMSL, indicating an adaptability to specific altitudinal gradients and the atmospheric conditions associated with such mid-to-high altitude ranges.

Elevational range mean:
1800 m AMSL
Habitat :
cropfields,parks

Life history

The life history of Nigella sativa is characterized by an annual lifecycle, meaning the plant completes its entire developmental process—from germination to seed production—within a single growing season. As a therophyte, it survives the unfavorable periods of its environment by completing its life cycle rapidly and persisting through seed dormancy rather than maintaining vegetative structures. This life form strategy allows it to efficiently utilize seasonal moisture and nutrients to reach maturity before the onset of harsh conditions, ensuring the continuity of the species through the dispersal of its seeds.

Life form :
therophyte
Lifecycle :
annual

Morphology

The morphology of Nigella sativa is characterized by its growth form as a non-woody herb, specifically classified as a forb. The plant is a self-supporting organism that does not function as a climber or a liana, maintaining an independent existence as it is neither a parasite nor an epiphyte, growing instead in a terrestrial habitat. In terms of stature, it is a relatively low-growing species with a plant height that typically ranges from a minimum of 0.2 m to a maximum of 0.5 m, resulting in an average height of approximately 0.2825 m.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
herb
Growth form :
forb
Parasite :
independent
Plant height max:
0.5 m
Plant height mean:
0.2825 m
Plant height min:
0.2 m
Woodiness :
non-woody

Physiology

The physiology of Nigella sativa is characterized by a C3 photosynthetic pathway, meaning it utilizes the Calvin cycle to fix carbon dioxide through the enzyme Rubisco, which is typical for many herbaceous annuals in the Ranunculaceae family. This metabolic process involves the direct fixation of CO2 into three-carbon compounds, making the plant's carbon assimilation efficiency highly dependent on environmental conditions such as temperature and water availability. Furthermore, Nigella sativa is not a nitrogen fixer; it lacks the specialized symbiotic relationship with rhizobia or other nitrogen-fixing bacteria required to convert atmospheric nitrogen into a usable form, and therefore relies on the uptake of nitrates and ammonium from the soil to satisfy its nutritional requirements for growth and development.

Nitrogen fixer :
no
Photosynthetic pathway :
C3

Reproduction

The reproductive cycle of Nigella sativa is characterized by a distinct seasonal flowering period that typically begins in June and concludes in August. The plant utilizes biotic pollination syndromes, specifically relying on insects such as bees to facilitate the fertilization process. Once fertilization occurs, the plant develops fruit in the form of a capsule, with a consistent length measuring approximately 1 cm (ranging from a minimum to a maximum of 1 cm). These capsules are dehiscent, meaning they split open to release the seeds. The resulting seeds are quite small, possessing a mean mass of 0.00141 g, with individual seed weights ranging from a minimum of 0.00051 g to a maximum of 0.00231 g. Regarding seed dispersal, the plant employs an unspecialized syndrome alongside anthropochorous dispersal, indicating that while it lacks a highly specialized natural mechanism, human activity plays a significant role in its distribution.

Dehiscence :
dehiscent
Dispersal syndrome :
unspecialized
Dispersal syndrome :
anthropochorous
Flowering time :
Jun
Flowering time :
Aug
Fruit length max:
1 cm
Fruit type :
capsule
Pollination syndrome :
insect
Pollination syndrome :
bee
Pollination syndrome :
biotic
Seed mass max:
0.00231 g
Seed mass mean:
0.00141 g
Seed mass min:
0.00051 g

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Nigella sativa has 2 reported plant parts identified across 72 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include seed, leaf.

Plant parts reported in Nigella sativa
Plant part Supporting sources Consensus
Seed 71 supporting sources ★★★★★
Leaf 1 supporting sources ★☆☆☆☆

Seed

  1. PloS one
  2. Saudi journal of biological sciences
  3. Fundamental & clinical pharmacology
  4. Iranian journal of basic medical sciences
  5. Journal of endocrinological investigation
View 66 additional sources
  1. Pakistan journal of biological sciences : PJBS
  2. International journal of immunopharmacology
  3. International journal of health sciences
  4. Infection and drug resistance
  5. Chemosphere
  6. Molecules (Basel, Switzerland)
  7. Immunopharmacology
  8. Journal of ethnopharmacology
  9. Asian Pacific journal of tropical biomedicine
  10. Journal of biomolecular structure & dynamics
  11. Chemical & pharmaceutical bulletin
  12. Journal of fish diseases
  13. Biochimica et biophysica acta
  14. Scientific reports
  15. Planta medica
  16. Journal of parasitic diseases : official organ of the Indian Society for Parasitology
  17. Pakistan journal of pharmaceutical sciences
  18. Toxicon : official journal of the International Society on Toxinology
  19. Pharmacological research
  20. Acta diabetologica latina
  21. Indian journal of experimental biology
  22. Drug research
  23. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  24. Therapie
  25. Organic letters
  26. Journal de pharmacie de Belgique
  27. BMC complementary and alternative medicine
  28. Food & function
  29. Journal of food science
  30. Phytomedicine : international journal of phytotherapy and phytopharmacology
  31. Biomedical chromatography : BMC
  32. Plants (Basel, Switzerland)
  33. Current pharmaceutical biotechnology
  34. Journal of natural products
  35. Chinese journal of natural medicines
  36. Acta biologica Hungarica
  37. Current drug discovery technologies
  38. Combinatorial chemistry & high throughput screening
  39. Environmental health insights
  40. Journal of food biochemistry
  41. JPMA. The Journal of the Pakistan Medical Association
  42. Clinical nutrition ESPEN
  43. Asian Pacific journal of cancer prevention : APJCP
  44. Metabolic brain disease
  45. Journal of oleo science
  46. Avicenna journal of phytomedicine
  47. BMC microbiology
  48. Food science and biotechnology
  49. Drug design, development and therapy
  50. Indian journal of physiology and pharmacology
  51. Journal of Ayub Medical College, Abbottabad : JAMC
  52. Journal of toxicology
  53. Chemistry & biodiversity
  54. Lipids in health and disease
  55. Toxicology and industrial health
  56. Natural product research
  57. Physiology international
  58. Journal of ethnobiology and ethnomedicine
  59. Complementary therapies in clinical practice
  60. African journal of traditional, complementary, and alternative medicines : AJTCAM
  61. Paediatric drugs
  62. Journal of pharmacy & bioallied sciences
  63. Inflammopharmacology
  64. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
  65. International immunopharmacology
  66. International journal of biological macromolecules

Leaf

  1. Life (Basel, Switzerland)

Chemicals

Nigella sativa has 192 reported phytochemicals identified across 72 scientific publications and several other databases. The most consistently reported chemicals include Thymoquinone, Flavonoids, THYMOL, linoleic acid, oil.

Chemicals reported in Nigella sativa
Chemical Supporting sources Consensus
Thymoquinone 68 supporting sources ★★★★★
Flavonoids 12 supporting sources ★★★★★
THYMOL 11 supporting sources ★★★★★
linoleic acid 10 supporting sources ★★★★★
oil 9 supporting sources ★★★★☆
CARVACROL 8 supporting sources ★★★★☆
Saponins 7 supporting sources ★★★★☆
Thymohydroquinone 7 supporting sources ★★★★☆
Fatty acids 6 supporting sources ★★★☆☆
Nigellidine 6 supporting sources ★★★☆☆

Thymoquinone

  1. Dr. Duke
  2. Pharmaceutical biology
  3. General pharmacology
  4. Letters in applied microbiology
  5. Cellular and molecular neurobiology
View 63 additional sources
  1. Journal of cardiovascular pharmacology
  2. Advanced pharmaceutical bulletin
  3. Plants (Basel, Switzerland)
  4. Evidence-based complementary and alternative medicine : eCAM
  5. Vascular health and risk management
  6. European journal of pharmacology
  7. Molecular cancer research : MCR
  8. Phytomedicine : international journal of phytotherapy and phytopharmacology
  9. Food science & nutrition
  10. Asian Pacific journal of tropical biomedicine
  11. Medicinal chemistry (Shariqah (United Arab Emirates))
  12. Parasites & vectors
  13. Avicenna journal of phytomedicine
  14. Research in pharmaceutical sciences
  15. Veterinary research forum : an international quarterly journal
  16. Planta medica
  17. Journal of chromatographic science
  18. The American journal of Chinese medicine
  19. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  20. Experimental parasitology
  21. International journal of nanomedicine
  22. Journal of ethnopharmacology
  23. Frontiers in nutrition
  24. Current aging science
  25. Journal of pharmacopuncture
  26. Current drug metabolism
  27. Molecules (Basel, Switzerland)
  28. Drug research
  29. CNS & neurological disorders drug targets
  30. Iranian journal of basic medical sciences
  31. Phytochemical analysis : PCA
  32. Food & function
  33. International journal of dermatology
  34. Open life sciences
  35. Current molecular medicine
  36. Frontiers in pharmacology
  37. Current pharmaceutical biotechnology
  38. Pharmaceutics
  39. PeerJ
  40. Yao xue xue bao = Acta pharmaceutica Sinica
  41. Food technology and biotechnology
  42. Food chemistry
  43. Metabolic brain disease
  44. Toxicology letters
  45. Drug design, development and therapy
  46. Journal of burn care & research : official publication of the American Burn Association
  47. Journal of applied toxicology : JAT
  48. Journal of tropical medicine
  49. Chemistry & biodiversity
  50. Cell biology international
  51. Current issues in molecular biology
  52. Anti-cancer agents in medicinal chemistry
  53. Critical reviews in food science and nutrition
  54. Phytotherapy research : PTR
  55. Phytochemistry
  56. Saudi journal of biological sciences
  57. Iranian journal of pharmaceutical research : IJPR
  58. African journal of traditional, complementary, and alternative medicines : AJTCAM
  59. Journal of oleo science
  60. Oncology letters
  61. Biochemistry research international
  62. Mini reviews in medicinal chemistry
  63. BMC complementary medicine and therapies

Flavonoids

  1. Journal of the science of food and agriculture
  2. Pakistan journal of pharmaceutical sciences
  3. TheScientificWorldJournal
  4. Frontiers in bioengineering and biotechnology
  5. Molecules (Basel, Switzerland)
View 7 additional sources
  1. Nutrients
  2. Iranian journal of basic medical sciences
  3. PeerJ
  4. Frontiers in pharmacology
  5. Food chemistry
  6. Pharmaceutical chemistry journal
  7. Food science & nutrition

THYMOL

  1. Dr. Duke
  2. Phytochemical analysis : PCA
  3. Foods (Basel, Switzerland)
  4. Journal of biomolecular structure & dynamics
  5. Medicinal chemistry (Shariqah (United Arab Emirates))
View 6 additional sources
  1. Journal of chromatographic science
  2. The American journal of Chinese medicine
  3. Journal of pharmacopuncture
  4. Journal of tropical medicine
  5. Journal de mycologie medicale
  6. BMC complementary medicine and therapies

linoleic acid

  1. Dr. Duke
  2. Zeitschrift fur Naturforschung. C, Journal of biosciences
  3. Advanced pharmaceutical bulletin
  4. Foods (Basel, Switzerland)
  5. Pakistan journal of pharmaceutical sciences
View 5 additional sources
  1. Evidence-based complementary and alternative medicine : eCAM
  2. Biochimica et biophysica acta
  3. Avicenna journal of phytomedicine
  4. Frontiers in pharmacology
  5. Chemistry & biodiversity

oil

  1. Trials
  2. Iranian journal of basic medical sciences
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  4. Journal of ethnopharmacology
  5. Acta biologica Hungarica
View 4 additional sources
  1. Journal of parasitic diseases : official organ of the Indian Society for Parasitology
  2. Pakistan journal of pharmaceutical sciences
  3. Saudi journal of biological sciences
  4. International immunopharmacology

CARVACROL

  1. Phytochemical analysis : PCA
  2. Journal of chromatographic science
  3. The American journal of Chinese medicine
  4. Journal of pharmacopuncture
  5. Journal of tropical medicine
View 3 additional sources
  1. Journal de mycologie medicale
  2. Critical reviews in food science and nutrition
  3. Biochemistry research international

Saponins

  1. Pakistan journal of pharmaceutical sciences
  2. TheScientificWorldJournal
  3. Food science & nutrition
  4. International journal of dermatology
  5. Frontiers in pharmacology
View 2 additional sources
  1. Food chemistry
  2. Critical reviews in food science and nutrition

Thymohydroquinone

  1. Dr. Duke
  2. Journal of biomolecular structure & dynamics
  3. The American journal of Chinese medicine
  4. Journal of pharmacopuncture
  5. Die Pharmazie
View 2 additional sources
  1. Food technology and biotechnology
  2. Journal of tropical medicine

Fatty acids

  1. Vascular health and risk management
  2. TheScientificWorldJournal
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Evidence-based complementary and alternative medicine : eCAM
  5. Izvestiia Akademii nauk. Seriia biologicheskaia
View 1 additional sources
  1. Iranian journal of basic medical sciences

Nigellidine

  1. Dr. Duke
  2. Chemistry & biodiversity
  3. The American journal of Chinese medicine
  4. Phytomedicine : international journal of phytotherapy and phytopharmacology
  5. Molecules (Basel, Switzerland)
View 1 additional sources
  1. Journal of tropical medicine

Activities

Nigella sativa has 403 reported activities identified across 72 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antimicrobial, Antidiabetic, Antibacterial.

Activities reported in Nigella sativa
Activity Supporting sources Consensus
Antioxidant 54 supporting sources ★★★★★
Anticancer 28 supporting sources ★★★★★
Antimicrobial 22 supporting sources ★★★★★
Antidiabetic 19 supporting sources ★★★★★
Antibacterial 17 supporting sources ★★★★★
Analgesic 14 supporting sources ★★★★★
Neuroprotective 13 supporting sources ★★★★★
Hepatoprotective 9 supporting sources ★★★★☆
Bronchodilator 8 supporting sources ★★★★☆
Antiviral 7 supporting sources ★★★★☆

Antioxidant

  1. Dr. Duke
  2. Integrative medicine research
  3. Current pharmaceutical biotechnology
  4. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  5. Journal of ovarian research
View 49 additional sources
  1. BMC complementary and alternative medicine
  2. Molecules (Basel, Switzerland)
  3. TheScientificWorldJournal
  4. Pharmaceutical biology
  5. Evidence-based complementary and alternative medicine : eCAM
  6. Food science & nutrition
  7. Journal of food science
  8. Parasites & vectors
  9. Naunyn-Schmiedeberg's archives of pharmacology
  10. The American journal of Chinese medicine
  11. BioMed research international
  12. Journal of traditional and complementary medicine
  13. International journal of nanomedicine
  14. Journal of ethnopharmacology
  15. Phytomedicine : international journal of phytotherapy and phytopharmacology
  16. Journal of pharmacopuncture
  17. Complementary therapies in clinical practice
  18. Drug research
  19. Iranian journal of basic medical sciences
  20. Biochemistry and biophysics reports
  21. Comptes rendus biologies
  22. Food & function
  23. Animals : an open access journal from MDPI
  24. International journal of biological macromolecules
  25. PeerJ
  26. Journal of food biochemistry
  27. Food technology and biotechnology
  28. Nutrients
  29. Metabolic brain disease
  30. Avicenna journal of phytomedicine
  31. Journal of applied toxicology : JAT
  32. Chemistry & biodiversity
  33. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
  34. Birth defects research
  35. Current issues in molecular biology
  36. Frontiers in bioengineering and biotechnology
  37. Pharmaceuticals (Basel, Switzerland)
  38. Iranian journal of pharmaceutical research : IJPR
  39. Dose-response : a publication of International Hormesis Society
  40. Phytotherapy research : PTR
  41. Journal of herbal medicine
  42. Medicina (Kaunas, Lithuania)
  43. Nutritional neuroscience
  44. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
  45. Oncology letters
  46. Frontiers in pharmacology
  47. International journal of molecular sciences
  48. Andrologia
  49. BMC complementary medicine and therapies

Anticancer

  1. Dr. Duke
  2. Molecular cancer research : MCR
  3. Molecules (Basel, Switzerland)
  4. Evidence-based complementary and alternative medicine : eCAM
  5. Asian Pacific journal of tropical biomedicine
View 23 additional sources
  1. Journal of food science
  2. Parasites & vectors
  3. Naunyn-Schmiedeberg's archives of pharmacology
  4. The American journal of Chinese medicine
  5. Frontiers in nutrition
  6. Frontiers in pharmacology
  7. Food & function
  8. International journal of biological macromolecules
  9. Scientific reports
  10. Heliyon
  11. PeerJ
  12. Drug and chemical toxicology
  13. Journal of food biochemistry
  14. Pakistan journal of pharmaceutical sciences
  15. Advanced pharmaceutical bulletin
  16. Cell biology international
  17. Anti-cancer agents in medicinal chemistry
  18. Frontiers in bioengineering and biotechnology
  19. Journal of biomolecular structure & dynamics
  20. Iranian journal of pharmaceutical research : IJPR
  21. Nutrients
  22. Journal of herbal medicine
  23. Biochemical and biophysical research communications

Antimicrobial

  1. Integrative medicine research
  2. BMC complementary and alternative medicine
  3. Evidence-based complementary and alternative medicine : eCAM
  4. Asian Pacific journal of tropical biomedicine
  5. Journal of food science
View 17 additional sources
  1. Naunyn-Schmiedeberg's archives of pharmacology
  2. The American journal of Chinese medicine
  3. Journal of ethnopharmacology
  4. Frontiers in nutrition
  5. Complementary therapies in clinical practice
  6. Drug research
  7. Current medicinal chemistry
  8. International journal of dermatology
  9. Drug and chemical toxicology
  10. Die Pharmazie
  11. Food chemistry
  12. BMC microbiology
  13. Current issues in molecular biology
  14. Iranian journal of pharmaceutical research : IJPR
  15. Journal of herbal medicine
  16. Environmental science and pollution research international
  17. BMC complementary medicine and therapies

Antidiabetic

  1. Dr. Duke
  2. Molecules (Basel, Switzerland)
  3. Evidence-based complementary and alternative medicine : eCAM
  4. Food science & nutrition
  5. Asian Pacific journal of tropical biomedicine
View 14 additional sources
  1. Journal of food science
  2. Journal of ethnopharmacology
  3. Frontiers in nutrition
  4. BMC complementary and alternative medicine
  5. Food & function
  6. International journal of dermatology
  7. PeerJ
  8. Journal of food biochemistry
  9. Frontiers in bioengineering and biotechnology
  10. Iranian journal of pharmaceutical research : IJPR
  11. Iranian biomedical journal
  12. Nutrients
  13. Journal of herbal medicine
  14. Medicina (Kaunas, Lithuania)

Antibacterial

  1. Dr. Duke
  2. Pakistan journal of pharmaceutical sciences
  3. Food science & nutrition
  4. Inflammopharmacology
  5. BioMed research international
View 12 additional sources
  1. Frontiers in nutrition
  2. Journal of ethnopharmacology
  3. International journal of biological macromolecules
  4. PeerJ
  5. Journal of food biochemistry
  6. Journal of oleo science
  7. Infection and drug resistance
  8. Journal of tropical medicine
  9. Current issues in molecular biology
  10. Frontiers in bioengineering and biotechnology
  11. Pharmaceuticals (Basel, Switzerland)
  12. The American journal of Chinese medicine

Analgesic

  1. Dr. Duke
  2. Integrative medicine research
  3. Phytomedicine : international journal of phytotherapy and phytopharmacology
  4. Asian Pacific journal of tropical biomedicine
  5. Inflammopharmacology
View 9 additional sources
  1. Naunyn-Schmiedeberg's archives of pharmacology
  2. International journal of dermatology
  3. Chinese journal of natural medicines
  4. Pakistan journal of pharmaceutical sciences
  5. Physiology international
  6. Iranian journal of pharmaceutical research : IJPR
  7. Complementary therapies in clinical practice
  8. Journal of herbal medicine
  9. Phytotherapy research : PTR

Neuroprotective

  1. Journal of traditional and complementary medicine
  2. International journal of molecular sciences
  3. Naunyn-Schmiedeberg's archives of pharmacology
  4. Pharmacological research
  5. CNS & neurological disorders drug targets
View 8 additional sources
  1. BioFactors (Oxford, England)
  2. Food & function
  3. Current molecular medicine
  4. Metabolic brain disease
  5. Birth defects research
  6. The American journal of Chinese medicine
  7. Nutritional neuroscience
  8. Frontiers in pharmacology

Hepatoprotective

  1. Dr. Duke
  2. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  3. Molecules (Basel, Switzerland)
  4. Pharmacological research
  5. Journal of pharmacopuncture
View 4 additional sources
  1. Food & function
  2. Journal of ethnopharmacology
  3. Endocrine, metabolic & immune disorders drug targets
  4. Journal of herbal medicine

Bronchodilator

  1. Asian Pacific journal of tropical biomedicine
  2. Naunyn-Schmiedeberg's archives of pharmacology
  3. International journal of dermatology
  4. Iranian journal of basic medical sciences
  5. JPMA. The Journal of the Pakistan Medical Association
View 3 additional sources
  1. Iranian journal of pharmaceutical research : IJPR
  2. Journal of herbal medicine
  3. Journal of pharmacy & bioallied sciences

Antiviral

  1. Dr. Duke
  2. Pharmaceutical biology
  3. Frontiers in pharmacology
  4. Food science & nutrition
  5. Saudi journal of biological sciences
View 2 additional sources
  1. Pharmaceutical chemistry journal
  2. Journal of tropical medicine

Medicinal Uses

Nigella sativa has 295 reported medicinal uses identified across 72 scientific publications and several other databases. The most consistently reported uses include cancer, oxidative stress, inflammation, COVID-19, hypertension.

Most Reported Uses

Use Sources Consensus
cancer Current pharmaceutical biotechnology (and other 29 sources) ★★★★★
oxidative stress Trials (and other 19 sources) ★★★★★
inflammation Trials (and other 17 sources) ★★★★★
COVID-19 Pharmaceutical biology (and other 14 sources) ★★★★★
hypertension Ibrain (and other 9 sources) ★★★★☆
Staphylococcus aureus Pakistan journal of pharmaceutical sciences (and other 8 sources) ★★★★☆
breast cancer Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (and other 8 sources) ★★★★☆
diabetes mellitus Ibrain (and other 8 sources) ★★★★☆
neurodegenerative diseases Ibrain (and other 8 sources) ★★★★☆
asthma Iranian journal of basic medical sciences (and other 7 sources) ★★★★☆

Preparations

Preparations Sources Consensus
seeds Saudi journal of biological sciences (and other 9 sources) ★★★★☆
oil Iranian journal of basic medical sciences (and other 8 sources) ★★★★☆
Nigella sativa oil Pakistan journal of biological sciences : PJBS (and other 6 sources) ★★★☆☆
extracts Global advances in integrative medicine and health (and other 6 sources) ★★★☆☆
NS oil Avicenna journal of phytomedicine (and other 5 sources) ★★★☆☆
hydro-alcoholic extract Journal of traditional and complementary medicine (and other 3 sources) ★★☆☆☆
methanolic extract Journal of endocrinological investigation (and other 3 sources) ★★☆☆☆
NSO International journal of molecular sciences (and other 2 sources) ★☆☆☆☆
Nigella sativa extract Pakistan journal of biological sciences : PJBS (and other 2 sources) ★☆☆☆☆
Nigella sativa seed oil Biochimica et biophysica acta (and other 2 sources) ★☆☆☆☆