Tobacco
Nicotiana tabacum · Accepted scientific name
Scientific literature: Very Extensive (1268 studies) · ★★★★★
Tobacco, scientifically known as Nicotiana tabacum, is a versatile plant belonging to the Solanaceae family. While widely recognized for its commercial cultivation and nicotine content, it holds significant historical importance in traditional medicine. This study explores its botanical characteristics, chemical properties, and the complex pharmacological effects of its alkaloids.
Names and Synonyms
Common Names
- Virginia tobacco
- cultivated tobacco
- Tobacco
Scientific Names
Accepted name
Nicotiana tabacumSynonyms
- Nicotiana tabacum var. lancifolia
- Nicotiana tabacum var. bullosa
- Nicotiana tabacum var. decimalis
- Nicotiana tabacum var. cordata
- Nicotiana tabacum var. loxensis
- Nicotiana crispula
- Nicotiana alipes
- Nicotiana alba
- Nicotiana latissima
- Nicotiana lancifolia
- Nicotiana capensis
- Nicotiana ybarrensis
- Nicotiana tabacum var. fruticosa
- Nicotiana loxensis
- Nicotiana fruticosa var. angustifolia
- Nicotiana macrophylla
- Nicotiana nepalensis
- Nicotiana auriculata
- Nicotiana havanensis
- Nicotiana gigantea
- Nicotiana gracilipes
- Nicotiana caudata
- Nicotiana chinensis
- Nicotiana angustifolia
- Nicotiana guatemalensis
- Nicotiana fruticosa
- Nicotiana frutescens
- Nicotiana virginica
- Nicotiana mexicana var. rubriflora
- Nicotiana tabacum var. angustifolia
- Nicotiana tabacum var. brasiliensis
- Nicotiana tabacum f. fruticosa
- Nicotiana tabacum var. undulata
- Nicotiana tabacum var. latissima
- Nicotiana tabacum var. lingua
- Nicotiana tabacum var. verdon
- Nicotiana tabacum var. serotina
- Nicotiana tabacum var. gracilipes
- Nicotiana tabacum var. attenuata
- Nicotiana tabacum var. pallescens
- Nicotiana tabacum var. alipes
- Nicotiana tabacum convar. latissima
- Nicotiana tabacum var. graeca
- Nicotiana tabacum var. pycnophylla
- Tabacum latissimum
- Nicotiana tabacum var. amesfortensis
- Nicotiana tabacum var. dinophylla
- Tabacum nicotianum
- Nicotiana tabacum var. alata
- Nicotiana tabacum var. chinensis
- Nicotiana tabacum f. attenuata
- Nicotiana tabacum convar. virginica
- Nicotiana mexicana
- Nicotiana fruticosa var. albiflora
- Nicotiana tabacum var. latior
- Nicotiana pilosa
- Nicotiana tabacum var. lanceolata
- Nicotiana tabacum var. gigantea
- Nicotiana tabacum var. nervosa
- Nicotiana sellowii
- Nicotiana sanguinea
- Nicotiana tabacum var. suffruticosa
- Nicotiana petiolata
- Nicotiana petiolaris
- Nicotiana tabacum var. macrophylla
Regional and Traditional Names
German:
- Virginischer Tabak
- virginischer Tabak
- Echter Tabak
French:
- tabac commun
- tabac cultivé
- grand tabac
- herbe à Nicot
- grand tabac
- nicotiane tabac
- tabac
- tabac commun
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant, Nicotiana tabacum, belongs to the kingdom Plantae and the phylum Streptophyta. It is classified within the class Equisetopsida and the subclass Magnoliidae, falling under the order Solanales and the family Solanaceae. Finally, it is categorized under the genus Nicotiana.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Solanales |
| Family | Solanaceae |
| Genus | Nicotiana |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a widespread presence across several regions of the European continent. In Northern Europe, its distribution includes the territories of Denmark and Great Britain. Moving toward Middle Europe, the species can be found growing within the borders of Austria and Belgium. Furthermore, its range extends into the central regions of Czechia-Slovakia. Collectively, these locations highlight the diverse geographical footprint of Nicotiana tabacum across these specific countries.
| Region | Area |
|---|---|
| Northern Europe | Denmark |
| Northern Europe | Great Britain |
| Middle Europe | Austria |
| Middle Europe | Belgium |
| Middle Europe | Czechia-Slovakia |
| Middle Europe | Germany |
| Middle Europe | Hungary |
| Middle Europe | Netherlands |
| Middle Europe | Switzerland |
| Southwestern Europe | Corse |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Nicotiana tabacum is characterized by its broad adaptability to diverse environments, primarily thriving within anthropic areas (Área Antrópica) where human activity and land management frequently influence its distribution. This species demonstrates a significant vertical distribution capacity, occupying a wide elevational range that extends from sea level (0 m AMSL) up to a maximum altitude of 3000 m AMSL. This vast altitudinal gradient allows the plant to persist in various climatic zones, ranging from lowland tropical settings to higher montane elevations.
- Elevational range max:
- 3000 m AMSL
- Elevational range min:
- 0 m AMSL
- Habitat :
- Área Antrópica
Genetics
The genetics of Nicotiana tabacum are characterized by significant chromosomal variation and complex ploidy levels across different accessions and varieties. The chromosome number within this species is notably diverse, with documented values including 23, 24, 46, 48, and 72. Despite this numerical variation, the plant is primarily identified with a diploid ploidy level, represented by a value of 2. This genetic architecture underpins the plant's physiological complexity and its ability to produce diverse secondary metabolites.
- Chromosome number :
- 23,24,46,48,72
- Ploidy :
- 2
Life history
The life history of Nicotiana tabacum is characterized by its classification as an annual plant, meaning it completes its entire developmental cycle—from germination and vegetative growth to flowering and seed production—within a single growing season. As a therophyte, the species survives unfavorable environmental conditions through the production of seeds, which remain dormant until optimal moisture and temperature levels are achieved. This life strategy allows the plant to rapidly exploit available resources, transitioning quickly from a seedling to a robust, large-leaved vegetative state before dedicating significant energy to the development of terminal inflorescences. Once pollination occurs, the plant directs its remaining metabolic resources into seed maturation, ultimately dying after the seeds are dispersed, thereby ensuring the continuation of the lineage in the next seasonal cycle.
- Life form :
- therophyte
- Lifecycle :
- annual
Morphology
The morphology of Nicotiana tabacum is characterized by its growth form as a non-woody herb and specifically a forb. This terrestrial plant is independent, meaning it does not function as a parasite or an epiphyte, maintaining a strictly terrestrial existence. It is a self-supporting plant rather than a climber, exhibiting an erect shoot orientation. In terms of stature, the plant displays significant variability in height, with a minimum height of 0.6 m, a mean height of 1.25 m, and a maximum potential height reaching up to 3 m.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Growth form :
- forb
- Parasite :
- independent
- Plant height max:
- 3 m
- Plant height mean:
- 1.25 m
- Plant height min:
- 0.6 m
- Shoot orientation :
- erect
- Woodiness :
- non-woody
Physiology
The physiology of Nicotiana tabacum is characterized by a C3 photosynthetic pathway, which governs its carbon fixation processes. The plant exhibits a non-carnivorous and non-succulent morphology, relying on standard nutrient uptake rather than nitrogen fixation or specialized water-storage tissues. Its foliage is arranged in an alternate pattern, featuring elliptic leaf forms that vary significantly in size. Morphological data indicates that leaf length ranges from a minimum of 10 cm to a mean of 20 cm, reaching a maximum of 50 cm. Correspondingly, leaf width fluctuates from a minimum of 5.4 cm to a mean of 12 cm, with a maximum width of 20 cm. Furthermore, the plant maintains a mean Specific Leaf Area (SLA) of 441 cm²/g, reflecting its leaf density and resource allocation strategies.
- Carnivory :
- non-carnivorous
- Leaf arrangement :
- alternate
- Leaf form :
- elliptic
- Leaf length max:
- 50 cm
- Leaf length mean:
- 20 cm
- Leaf length min:
- 10 cm
- Leaf width max:
- 20 cm
- Leaf width mean:
- 12 cm
- Leaf width min:
- 5.4 cm
- Nitrogen fixer :
- no
- Photosynthetic pathway :
- C3
- Specific Leaf Area (SLA) mean:
- 441 cm²/g
- Succulence :
- no
Reproduction
The reproduction of Nicotiana tabacum is characterized by a specialized flowering period that typically begins in July and concludes in September. The plant produces red flowers that vary in size, with lengths ranging from a minimum of 0.5 cm to a maximum of 6 cm. These flowers rely on biotic pollination syndromes, specifically utilizing insects such as bees to facilitate fertilization. Following successful pollination, the plant develops a dry, dehiscent fruit classified as a capsule. These capsules exhibit moderate dimensions, with a mean length of 1.8 cm (ranging from 1.5 cm to 2.5 cm) and a mean width of 1 cm. The resulting seeds are minute, with a mean mass of 9.5e-05 g (ranging from 1e-05 g to 0.00013 g) and a mean length of 0.6 mm (with a maximum of 0.5 mm). The seed volume is highly consistent at 0.048 mm³. Dispersal of the seeds is characterized by an unspecialized syndrome, though it also exhibits anthropochorous tendencies, meaning human activity plays a role in its spread.
- Dehiscence :
- dehiscent
- Dispersal syndrome :
- unspecialized
- Dispersal syndrome :
- anthropochorous
- Flower colour :
- red
- Flower length max:
- 6 cm
- Flower length min:
- 0.5 cm
- Flowering time :
- Jul
- Flowering time :
- Sep
- Fruit dryness :
- dry
- Fruit length max:
- 2.5 cm
- Fruit length mean:
- 1.8 cm
- Fruit length min:
- 1.5 cm
- Fruit type :
- capsule
- Fruit width mean:
- 1 cm
- Pollination syndrome :
- insect
- Pollination syndrome :
- bee
- Pollination syndrome :
- biotic
- Seed length max:
- 0.5 mm
- Seed length mean:
- 0.6 mm
- Seed mass max:
- 0.00013 g
- Seed mass mean:
- 9.5e-05 g
- Seed mass min:
- 1e-05 g
- Seed volume max:
- 0.048 mm³
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Nicotiana tabacum has 2 reported plant parts identified across 12 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, root.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Leaf | 11 supporting sources | ★★★★★ |
| Root | 1 supporting sources | ★☆☆☆☆ |
Leaf
- TheScientificWorldJournal
- Journal of parasitology research
- Parasite epidemiology and control
- Biomolecules
- Journal of Asian natural products research
View 6 additional sources
- Parasitology
- Mutation research
- Fitoterapia
- Plant physiology and biochemistry : PPB
- Preventive veterinary medicine
- Plant biotechnology journal
Root
- Plant physiology and biochemistry : PPB
Chemicals
Nicotiana tabacum has 365 reported phytochemicals identified across 12 scientific publications and several other databases. The most consistently reported chemicals include nicotine, Flavonoids, Solanesol, Anabasine, LIGNIN.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| nicotine | 26 supporting sources | ★★★★★ |
| Flavonoids | 8 supporting sources | ★★★★☆ |
| Solanesol | 5 supporting sources | ★★★☆☆ |
| Anabasine | 4 supporting sources | ★★☆☆☆ |
| LIGNIN | 4 supporting sources | ★★☆☆☆ |
| STARCH | 4 supporting sources | ★★☆☆☆ |
| STIGMASTEROL | 4 supporting sources | ★★☆☆☆ |
| 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE | 3 supporting sources | ★★☆☆☆ |
| ANTHOCYANIN | 3 supporting sources | ★★☆☆☆ |
| Anthocyanins | 3 supporting sources | ★★☆☆☆ |
nicotine
- Dr. Duke
- Plant physiology and biochemistry : PPB
- Przeglad lekarski
- The American journal of clinical nutrition
- Physiologia plantarum
View 21 additional sources
- Indian journal of dental research : official publication of Indian Society for Dental Research
- TheScientificWorldJournal
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Scientific reports
- Plant signaling & behavior
- IARC scientific publications
- Polish journal of pharmacology
- PloS one
- Journal of B.U.ON. : official journal of the Balkan Union of Oncology
- Environmental science and pollution research international
- Psychopharmacology
- Journal of toxicology and environmental health
- Chirality
- Immunopharmacology and immunotoxicology
- Frontiers in pharmacology
- Carcinogenesis
- Journal of hazardous materials
- Current pharmaceutical biotechnology
- Tobacco control
- Harm reduction journal
- Journal of clinical periodontology
Flavonoids
- TheScientificWorldJournal
- Journal of agricultural and food chemistry
- Journal of parasitology research
- PloS one
- Frontiers in plant science
View 3 additional sources
- Molecular omics
- Frontiers in microbiology
- Insects
Solanesol
- Dr. Duke
- Journal of bioscience and bioengineering
- Scientific reports
- Biomolecules
- Frontiers in pharmacology
Anabasine
- Dr. Duke
- Physiologia plantarum
- Scientific reports
- PloS one
LIGNIN
- Dr. Duke
- Scientific reports
- Molecular plant pathology
- Plant, cell & environment
STARCH
- Dr. Duke
- Physiologia plantarum
- International journal of molecular sciences
- Scientific reports
STIGMASTEROL
- Dr. Duke
- Plant cell reports
- Planta
- Molecular plant pathology
4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE
- Cancer research
- Journal of cancer research and clinical oncology
- Journal of toxicology and environmental health
ANTHOCYANIN
- Science China. Life sciences
- Plant molecular biology
- Plant, cell & environment
Anthocyanins
- Plants (Basel, Switzerland)
- Physiologia plantarum
- Frontiers in plant science
Activities
Nicotiana tabacum has 632 reported activities identified across 12 scientific publications and several other databases. The most consistently reported activities include Mutagenic, Neuroprotective, Antimicrobial, Antioxidant, Antitumor.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Mutagenic | 3 supporting sources | ★★☆☆☆ |
| Neuroprotective | 3 supporting sources | ★★☆☆☆ |
| Antimicrobial | 2 supporting sources | ★☆☆☆☆ |
| Antioxidant | 2 supporting sources | ★☆☆☆☆ |
| Antitumor | 2 supporting sources | ★☆☆☆☆ |
| Carcinogenic | 2 supporting sources | ★☆☆☆☆ |
| Cytotoxic | 2 supporting sources | ★☆☆☆☆ |
| Phytoalexin | 2 supporting sources | ★☆☆☆☆ |
| (-)-Chronotropic | 1 supporting sources | ★☆☆☆☆ |
| (-)-Inotropic | 1 supporting sources | ★☆☆☆☆ |
Mutagenic
- Dr. Duke
- The National medical journal of India
- Nutrition and cancer
Neuroprotective
- Dr. Duke
- Biomolecules
- Pharmaceuticals (Basel, Switzerland)
Antimicrobial
- Biomolecules
- Pharmaceuticals (Basel, Switzerland)
Antioxidant
- Dr. Duke
- Molecules (Basel, Switzerland)
Antitumor
- Dr. Duke
- Pharmaceuticals (Basel, Switzerland)
Carcinogenic
- Dr. Duke
- The National medical journal of India
Cytotoxic
- Dr. Duke
- Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Phytoalexin
- Dr. Duke
- Journal of experimental botany
(-)-Chronotropic
- Dr. Duke
(-)-Inotropic
- Dr. Duke
Conditions
Nicotiana tabacum has 67 reported investigations on conditions identified across 12 scientific publications and several other databases. The most consistently reported conditions include oral cancer, lung cancer, tobacco mosaic virus, cell death, drought.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Oral cancer | 6 supporting sources | ★★★☆☆ |
| Lung cancer | 4 supporting sources | ★★☆☆☆ |
| Tobacco mosaic virus | 4 supporting sources | ★★☆☆☆ |
| Cell death | 3 supporting sources | ★★☆☆☆ |
| Drought | 3 supporting sources | ★★☆☆☆ |
| Parkinson's disease | 2 supporting sources | ★☆☆☆☆ |
| Biotic stress | 2 supporting sources | ★☆☆☆☆ |
| Cancer | 2 supporting sources | ★☆☆☆☆ |
| Heat stress | 2 supporting sources | ★☆☆☆☆ |
| Leishmaniasis | 2 supporting sources | ★☆☆☆☆ |
Oral cancer
- Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
- Carcinogenesis
- Neoplasma
- Oral oncology
- Community dental health
View 1 additional sources
- International journal of cancer
Lung cancer
- Journal of agricultural and food chemistry
- Journal of B.U.ON. : official journal of the Balkan Union of Oncology
- Journal of toxicology and environmental health
- Bulletin of the Indian Institute of History of Medicine (Hyderabad)
Tobacco mosaic virus
- Pest management science
- Natural product research
- Planta medica
- Journal of agricultural and food chemistry
Cell death
- Frontiers in plant science
- Journal of experimental botany
- Molecules (Basel, Switzerland)
Drought
- International journal of molecular sciences
- Zeitschrift fur Naturforschung. C, Journal of biosciences
- Scientific reports
Parkinson's disease
- Przeglad lekarski
- Frontiers in pharmacology
Biotic stress
- Planta
- The New phytologist
Cancer
- Plant physiology and biochemistry : PPB
- Human vaccines
Heat stress
- Protoplasma
- Plant science : an international journal of experimental plant biology
Leishmaniasis
- Parasite epidemiology and control
- Frontiers in pharmacology
Preparations
Nicotiana tabacum has 24 reported preparations identified across 12 scientific publications and several other databases. The most consistently reported preparations include leaves, Smokeless tobacco products, cell suspension cultures, chemma, chewed.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Leaves | 2 supporting sources | ★☆☆☆☆ |
| Smokeless tobacco products | 1 supporting sources | ★☆☆☆☆ |
| Cell suspension cultures | 1 supporting sources | ★☆☆☆☆ |
| Chemma | 1 supporting sources | ★☆☆☆☆ |
| Chewed | 1 supporting sources | ★☆☆☆☆ |
| Chloroform extracts | 1 supporting sources | ★☆☆☆☆ |
| Crude extracts | 1 supporting sources | ★☆☆☆☆ |
| Crude methanolic extract of leaves | 1 supporting sources | ★☆☆☆☆ |
| Crude methanolic extracts of leaves | 1 supporting sources | ★☆☆☆☆ |
| Fermentation of endophytic aspergillus fumigatus 0338 | 1 supporting sources | ★☆☆☆☆ |
Leaves
- Parasitology
- Preventive veterinary medicine
Smokeless tobacco products
- TheScientificWorldJournal
Cell suspension cultures
- Zeitschrift fur Naturforschung. C, Journal of biosciences
Chemma
- TheScientificWorldJournal
Chewed
- TheScientificWorldJournal
Chloroform extracts
- Frontiers in veterinary science
Crude extracts
- Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences
Crude methanolic extract of leaves
- Journal of parasitology research
Crude methanolic extracts of leaves
- Journal of parasitology research
Fermentation of endophytic aspergillus fumigatus 0338
- Pesticide biochemistry and physiology