10 Possible Side Effects Of Myristica Fragrans (Nutmeg)

Myristica fragrans has some side effects when used improperly, such as headaches, dizziness, and nausea.

These side effects can occur due to excessive consumption of the herb's volatile oil, myristicin. In severe cases, myristicin can cause hallucinations and seizures.

For individuals with pre-existing medical conditions, these side effects can worsen their condition and impact their daily lives significantly, making it challenging to maintain work or social routines.

This article explains in details the 10 most common side effects of Myristica fragrans if used imporperly.

1. Increases heart rate

Myristica fragrans causes allergic reactions.

The allergenic compounds present in its essential oil, particularly myristicin and elemicin, can trigger an immune response in some individuals.

These chemical components can bind to antibodies, leading to the release of histamine, a potent inflammatory mediator that triggers symptoms such as hives, itching, and flushing.

2. Increases heart rate

Myristica fragrans triggers skin irritation due to its essential oil content containing myristicin and elemicin.

These compounds can cause contact dermatitis, characterized by redness, itching, and rashes on the skin upon exposure.

Additionally, the oil's high concentration of volatile phenolic compounds may exacerbate allergic reactions, leading to inflammation and discomfort.

3. Increases heart rate

Myristica fragrans leads to liver damage due to its high concentration of myristicin and elemicin.

These compounds can cause significant hepatotoxicity, leading to inflammation and cellular damage in the liver.

When consumed in large quantities or for extended periods, these toxic compounds can accumulate and cause irreversible harm to the liver.

4. Increases heart rate

Myristica fragrans increases risk of bleeding due to its high concentration of coumarin derivatives.

These compounds inhibit blood coagulation by interfering with platelet aggregation and vitamin K-dependent clotting factors, which can lead to excessive bleeding.

Additionally, the seed's essential oil contains eugenol, a natural anticoagulant that further contributes to this risk.

5. Increases heart rate

Myristica fragrans induces kidney stones due to its high content of coumarin and myristicin.

These compounds can increase urine acidity, leading to the formation of insoluble calcium oxalate crystals that may combine with other minerals to form stones in the kidneys.

Additionally, nutmeg's ability to stimulate digestive enzymes can also contribute to increased uric acid production, further increasing the risk of kidney stone development.

6. Increases heart rate

Myristica fragrans affects blood pressure.

The volatile oils present in the seeds of this plant can cause a sudden and temporary increase in blood pressure due to its stimulatory effects on the cardiovascular system.

This is attributed to the presence of myristicin and elemicin, compounds that can stimulate the heart rate and constrict blood vessels, leading to an elevation in blood pressure.

7. Increases heart rate

Myristica fragrans produces hallucinations due to the presence of a psychoactive compound called myristicin.

When consumed in large amounts or combined with other substances, myristicin can alter the brain's neurotransmitter activity, leading to distortions in perception and thinking.

This can result in vivid hallucinations, as well as altered states of consciousness.

8. Increases heart rate

Myristica fragrans disrupts respiratory system by releasing volatile oils that can cause bronchospasm and exacerbate existing respiratory conditions such as asthma.

The essential oil, myristicin, in particular, has been shown to increase the production of mucus, leading to congestion and breathing difficulties.

Additionally, the psychoactive compound, mesuagenine, may induce allergic reactions, further complicating respiratory issues.

9. Increases heart rate

Myristica fragrans worsens epilepsy due to its ability to lower the threshold for seizure activity in individuals already prone to seizures.

The main culprit is myristicin, a chemical compound found in the plant, which can increase the excitability of brain cells and disrupt normal neuronal function.

This can lead to an increased likelihood of seizures in people with epilepsy, making it essential for those affected by this condition to avoid using Myristica fragrans altogether.

10. Increases heart rate

Myristica fragrans interferes with warfarin by altering its metabolism in the liver.

The active compounds in nutmeg, particularly myristicin and elemicin, are potent inhibitors of cytochrome P450 enzymes, which are responsible for breaking down warfarin.

This interference can lead to increased levels of warfarin in the blood, potentially causing adverse effects or altering its therapeutic efficacy.