velvet bean
Mucuna pruriens · Accepted scientific name
Scientific literature: Very Extensive (291 studies) · ★★★★★
Velvet bean, scientifically known as Mucuna pruriens, is a tropical climbing legume renowned for its potent medicinal properties. Rich in L-dopa, it is widely used in traditional medicine to support neurological health, manage Parkinson's symptoms, and balance hormones. This versatile plant offers significant potential for modern therapeutic applications.
Names
Common Names
- cow-itch
- cowage
- velvet-bean
- Itchy bean
- Velvet bean
- cowitch
Regional and Traditional Names
Spanish:
- Nescafe
- Ojo de venado
- Chiporro
- Frijol terciopelo
- Grano de terciopelo
- Grano de mar
- Kapikachu
- Chiporazo
- Fogaraté
- frijol terciopelo
German:
- Juckbohne
- Juckbohne
French:
- Pois mascate
- Pois pouilleux
- Pois à gratter
- poil à gratter
- Pois mascate
Scientific Names
Accepted name
Mucuna pruriensSynonyms
- Carpopogon pruriens
- Dolichos pruriens
- Stizolobium pruriens
- Labradia pruriens
- Negretia pruriens
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Fabales and the family Fabaceae. Specifically, its taxonomic identity is defined by the genus Mucuna, which includes the medicinal species Mucuna pruriens.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Fabales | WCVP |
| Family | Fabaceae | WCVP |
| Genus | Mucuna | WCVP |
Distribution
This plant exhibits a broad geographical distribution across several distinct tropical regions. In the Macaronesian islands, it can be specifically found in Cape Verde. Moving to the mainland, it is widely distributed throughout West Tropical Africa. Its presence is documented in several countries, including Benin, Burkina, and Ghana. Additionally, the species extends its range into Guinea-Bissau within the same West Tropical African zone.
| Region | Area | Source |
|---|---|---|
| Macaronesia | Cape Verde | WCVP |
| West Tropical Africa | Benin | WCVP |
| West Tropical Africa | Burkina | WCVP |
| West Tropical Africa | Ghana | WCVP |
| West Tropical Africa | Guinea-Bissau | WCVP |
| West Tropical Africa | Guinea | WCVP |
| West Tropical Africa | Ivory Coast | WCVP |
| West Tropical Africa | Liberia | WCVP |
| West Tropical Africa | Nigeria | WCVP |
| West Tropical Africa | Senegal | WCVP |
Plant Parts
This plant, known for its potent therapeutic properties, utilizes various components for medicinal purposes. The most widely recognized part is the seeds, often referred to as the single seed or the collective seeds, which are highly valued for their high concentration of L-dopa. Additionally, the leaves and roots are frequently studied and used in traditional practices to treat various ailments. The plant also produces distinct pods that protect the developing seeds, making the entire structure of Mucuna pruriens a subject of great interest in herbal medicine.| Plant Part | Sources | Consensus |
|---|---|---|
| seed | Indian journal of pharmaceutical sciences (and other 16 sources) | ★★★★★ |
| leaf | Planta (and other 6 sources) | ★★★☆☆ |
| root | Planta medica (and other 3 sources) | ★★☆☆☆ |
| stem | Planta (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Mucuna pruriens has 48 reported phytochemicals identified across 26 scientific publications and several other databases. The most consistently reported chemicals include L-dopa, dopamine, levodopa, 17-beta-estradiol, 2-Hydroxyestradiol.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| L-dopa | 12 supporting sources | ★★★★★ |
| dopamine | 2 supporting sources | ★☆☆☆☆ |
| levodopa | 2 supporting sources | ★☆☆☆☆ |
| 17-beta-estradiol | 1 supporting sources | ★☆☆☆☆ |
| 2-Hydroxyestradiol | 1 supporting sources | ★☆☆☆☆ |
| 2-phenylethylamine | 1 supporting sources | ★☆☆☆☆ |
| 4-HYDROXYESTRADIOL | 1 supporting sources | ★☆☆☆☆ |
| 9,12-Octadecadienoic acid (Z,Z)- | 1 supporting sources | ★☆☆☆☆ |
| AFB1 | 1 supporting sources | ★☆☆☆☆ |
| AFB2 | 1 supporting sources | ★☆☆☆☆ |
L-dopa
- Indian journal of pharmaceutical sciences
- Planta
- BMC genomics
- Heliyon
- PloS one
View 7 additional sources
- Scientific reports
- International journal of radiation biology
- International journal of food sciences and nutrition
- Journal of ethnopharmacology
- DNA research : an international journal for rapid publication of reports on genes and genomes
- Phytochemistry
- Indian journal of biochemistry & biophysics
dopamine
- Planta
- Neurochemistry international
levodopa
- Movement disorders : official journal of the Movement Disorder Society
- Phytotherapy research : PTR
17-beta-estradiol
- Phytochemistry
2-Hydroxyestradiol
- Phytochemistry
2-phenylethylamine
- Journal of ethnopharmacology
4-HYDROXYESTRADIOL
- Phytochemistry
9,12-Octadecadienoic acid (Z,Z)-
- Journal of ethnopharmacology
AFB1
- Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
AFB2
- Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
Activities
Mucuna pruriens has 79 reported activities identified across 26 scientific publications and several other databases. The most consistently reported activities include Aphrodisiac, Antioxidant, Neuroprotective, Antimicrobial, Fertility-Enhancing.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Aphrodisiac | Journal of biological regulators and homeostatic agents (and other 7 sources) | ★★★★☆ |
| Antioxidant | Dr. Duke (and other 6 sources) | ★★★☆☆ |
| Neuroprotective | Neurochemical research (and other 4 sources) | ★★☆☆☆ |
| Antimicrobial | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Fertility-Enhancing | Pakistan journal of pharmaceutical sciences (and other 2 sources) | ★☆☆☆☆ |
| Abortifacient | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Adaptogenic | PloS one (and other 1 sources) | ★☆☆☆☆ |
| Aldose-Reductase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Alpha-Reductase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Antiaggregant | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Mucuna pruriens has 39 reported medicinal uses identified across 26 scientific publications and several other databases. The most consistently reported uses include Parkinson's disease, neurodegenerative diseases, aphrodisiac, male infertility, Alzheimer's disease.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| Parkinson's disease | Indian journal of pharmaceutical sciences (and other 15 sources) | ★★★★★ |
| neurodegenerative diseases | Journal of ethnopharmacology (and other 5 sources) | ★★★☆☆ |
| aphrodisiac | Heliyon (and other 3 sources) | ★★☆☆☆ |
| male infertility | Neurochemical research (and other 3 sources) | ★★☆☆☆ |
| Alzheimer's disease | Neurochemical research (and other 2 sources) | ★☆☆☆☆ |
| infertility | Journal of complementary & integrative medicine (and other 2 sources) | ★☆☆☆☆ |
| oxidative stress | BMC complementary and alternative medicine (and other 2 sources) | ★☆☆☆☆ |
| snake venom | The Journal of biological chemistry (and other 2 sources) | ★☆☆☆☆ |
| snakebite | The Journal of biological chemistry (and other 2 sources) | ★☆☆☆☆ |
| Amyotrophic lateral sclerosis | Neurochemical research (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| seeds | Frontiers in plant science (and other 3 sources) | ★★☆☆☆ |
| extracts | BMC complementary and alternative medicine (and other 2 sources) | ★☆☆☆☆ |
| 'Amrita Oil' | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| 'Amrita-Prâsa clarified butter' | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Mp leaf methanolic extract | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| PHP | Reproductive sciences (Thousand Oaks, Calif.) (and other 1 sources) | ★☆☆☆☆ |
| alcohol extract of the seeds | Phytotherapy research : PTR (and other 1 sources) | ★☆☆☆☆ |
| autoclaving | International journal of food sciences and nutrition (and other 1 sources) | ★☆☆☆☆ |
| cooking | International journal of food sciences and nutrition (and other 1 sources) | ★☆☆☆☆ |
| crude extracts | Andrologia (and other 1 sources) | ★☆☆☆☆ |