velvet bean

Mucuna pruriens · Accepted scientific name

Scientific literature: Very Extensive (291 studies) · ★★★★★

Velvet bean, scientifically known as Mucuna pruriens, is a tropical climbing legume renowned for its potent medicinal properties. Rich in L-dopa, it is widely used in traditional medicine to support neurological health, manage Parkinson's symptoms, and balance hormones. This versatile plant offers significant potential for modern therapeutic applications.

Family
Fabaceae
Native range
Africa
Parts used
Seed · Leaf
Common names
Cow-Itch · Cowage · 4 more
Scientific synonyms
Carpopogon Pruriens · Dolichos Pruriens · 3 more

Names

Common Names

Regional and Traditional Names

Spanish:

  • Nescafe
  • Ojo de venado
  • Chiporro
  • Frijol terciopelo
  • Grano de terciopelo
  • Grano de mar
  • Kapikachu
  • Chiporazo
  • Fogaraté
  • frijol terciopelo

German:

  • Juckbohne
  • Juckbohne

French:

  • Pois mascate
  • Pois pouilleux
  • Pois à gratter
  • poil à gratter
  • Pois mascate

Scientific Names

Accepted name

Mucuna pruriens

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Fabales and the family Fabaceae. Specifically, its taxonomic identity is defined by the genus Mucuna, which includes the medicinal species Mucuna pruriens.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Fabales WCVP
Family Fabaceae WCVP
Genus Mucuna WCVP

Distribution

This plant exhibits a broad geographical distribution across several distinct tropical regions. In the Macaronesian islands, it can be specifically found in Cape Verde. Moving to the mainland, it is widely distributed throughout West Tropical Africa. Its presence is documented in several countries, including Benin, Burkina, and Ghana. Additionally, the species extends its range into Guinea-Bissau within the same West Tropical African zone.

Region Area Source
Macaronesia Cape Verde WCVP
West Tropical Africa Benin WCVP
West Tropical Africa Burkina WCVP
West Tropical Africa Ghana WCVP
West Tropical Africa Guinea-Bissau WCVP
West Tropical Africa Guinea WCVP
West Tropical Africa Ivory Coast WCVP
West Tropical Africa Liberia WCVP
West Tropical Africa Nigeria WCVP
West Tropical Africa Senegal WCVP

Plant Parts

This plant, known for its potent therapeutic properties, utilizes various components for medicinal purposes. The most widely recognized part is the seeds, often referred to as the single seed or the collective seeds, which are highly valued for their high concentration of L-dopa. Additionally, the leaves and roots are frequently studied and used in traditional practices to treat various ailments. The plant also produces distinct pods that protect the developing seeds, making the entire structure of Mucuna pruriens a subject of great interest in herbal medicine.
Plant Part Sources Consensus
seed Indian journal of pharmaceutical sciences (and other 16 sources) ★★★★★
leaf Planta (and other 6 sources) ★★★☆☆
root Planta medica (and other 3 sources) ★★☆☆☆
stem Planta (and other 1 sources) ★☆☆☆☆

Chemicals

Mucuna pruriens has 48 reported phytochemicals identified across 26 scientific publications and several other databases. The most consistently reported chemicals include L-dopa, dopamine, levodopa, 17-beta-estradiol, 2-Hydroxyestradiol.

Chemicals reported in Mucuna pruriens
Chemical Supporting sources Consensus
L-dopa 12 supporting sources ★★★★★
dopamine 2 supporting sources ★☆☆☆☆
levodopa 2 supporting sources ★☆☆☆☆
17-beta-estradiol 1 supporting sources ★☆☆☆☆
2-Hydroxyestradiol 1 supporting sources ★☆☆☆☆
2-phenylethylamine 1 supporting sources ★☆☆☆☆
4-HYDROXYESTRADIOL 1 supporting sources ★☆☆☆☆
9,12-Octadecadienoic acid (Z,Z)- 1 supporting sources ★☆☆☆☆
AFB1 1 supporting sources ★☆☆☆☆
AFB2 1 supporting sources ★☆☆☆☆

L-dopa

  1. Indian journal of pharmaceutical sciences
  2. Planta
  3. BMC genomics
  4. Heliyon
  5. PloS one
View 7 additional sources
  1. Scientific reports
  2. International journal of radiation biology
  3. International journal of food sciences and nutrition
  4. Journal of ethnopharmacology
  5. DNA research : an international journal for rapid publication of reports on genes and genomes
  6. Phytochemistry
  7. Indian journal of biochemistry & biophysics

dopamine

  1. Planta
  2. Neurochemistry international

levodopa

  1. Movement disorders : official journal of the Movement Disorder Society
  2. Phytotherapy research : PTR

17-beta-estradiol

  1. Phytochemistry

2-Hydroxyestradiol

  1. Phytochemistry

2-phenylethylamine

  1. Journal of ethnopharmacology

4-HYDROXYESTRADIOL

  1. Phytochemistry

9,12-Octadecadienoic acid (Z,Z)-

  1. Journal of ethnopharmacology

AFB1

  1. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques

AFB2

  1. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques

Activities

Mucuna pruriens has 79 reported activities identified across 26 scientific publications and several other databases. The most consistently reported activities include Aphrodisiac, Antioxidant, Neuroprotective, Antimicrobial, Fertility-Enhancing.

Most Reported Activities

Activity Sources Consensus
Aphrodisiac Journal of biological regulators and homeostatic agents (and other 7 sources) ★★★★☆
Antioxidant Dr. Duke (and other 6 sources) ★★★☆☆
Neuroprotective Neurochemical research (and other 4 sources) ★★☆☆☆
Antimicrobial Dr. Duke (and other 2 sources) ★☆☆☆☆
Fertility-Enhancing Pakistan journal of pharmaceutical sciences (and other 2 sources) ★☆☆☆☆
Abortifacient Dr. Duke (and other 1 sources) ★☆☆☆☆
Adaptogenic PloS one (and other 1 sources) ★☆☆☆☆
Aldose-Reductase-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
Alpha-Reductase-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
Antiaggregant Dr. Duke (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Mucuna pruriens has 39 reported medicinal uses identified across 26 scientific publications and several other databases. The most consistently reported uses include Parkinson's disease, neurodegenerative diseases, aphrodisiac, male infertility, Alzheimer's disease.

Most Reported Uses

Use Sources Consensus
Parkinson's disease Indian journal of pharmaceutical sciences (and other 15 sources) ★★★★★
neurodegenerative diseases Journal of ethnopharmacology (and other 5 sources) ★★★☆☆
aphrodisiac Heliyon (and other 3 sources) ★★☆☆☆
male infertility Neurochemical research (and other 3 sources) ★★☆☆☆
Alzheimer's disease Neurochemical research (and other 2 sources) ★☆☆☆☆
infertility Journal of complementary & integrative medicine (and other 2 sources) ★☆☆☆☆
oxidative stress BMC complementary and alternative medicine (and other 2 sources) ★☆☆☆☆
snake venom The Journal of biological chemistry (and other 2 sources) ★☆☆☆☆
snakebite The Journal of biological chemistry (and other 2 sources) ★☆☆☆☆
Amyotrophic lateral sclerosis Neurochemical research (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
seeds Frontiers in plant science (and other 3 sources) ★★☆☆☆
extracts BMC complementary and alternative medicine (and other 2 sources) ★☆☆☆☆
'Amrita Oil' Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
'Amrita-Prâsa clarified butter' Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Mp leaf methanolic extract Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
PHP Reproductive sciences (Thousand Oaks, Calif.) (and other 1 sources) ★☆☆☆☆
alcohol extract of the seeds Phytotherapy research : PTR (and other 1 sources) ★☆☆☆☆
autoclaving International journal of food sciences and nutrition (and other 1 sources) ★☆☆☆☆
cooking International journal of food sciences and nutrition (and other 1 sources) ★☆☆☆☆
crude extracts Andrologia (and other 1 sources) ★☆☆☆☆