bitter gourd

Momordica charantia · Accepted scientific name

Scientific literature: Very Extensive (1198 studies) · ★★★★★

Bitter gourd, scientifically known as Momordica charantia, is a versatile medicinal plant widely celebrated in traditional healing systems. Renowned for its potent bioactive compounds, it is primarily used to manage blood sugar levels, support digestive health, and provide antioxidant benefits, making it a vital staple in holistic wellness practices.

Family
Cucurbitaceae
Native range
Africa
Parts used
Fruit · Seed
Common names
Balsam-Pear · Bitter Gourd · 13 more
Scientific synonyms
Not available

Names and Synonyms

Common Names

Scientific Names

Accepted name

Momordica charantia

Regional and Traditional Names

Spanish:

  • balsamito
  • bálsamo
  • cundeamor
  • Balsamina
  • Pepino cimarrón

German:

  • Bittermelone
  • Balsambirne
  • Balsamapfel
  • Bittere Springgurke
  • Bittergurke
  • Goya-Gurke
  • Balsambirne
  • Bittergurke
  • amerikanische Bittergurke
  • Bittermelone

French:

  • margose
  • melon amer
  • momordique
  • concombre africain
  • margose
  • momordique
  • paroka
  • Melon amer

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Cucurbitales, it is classified under the family Cucurbitaceae. Finally, it is identified by the genus Momordica, with the specific species name being charantia.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Cucurbitales
Family Cucurbitaceae
Genus Momordica

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, Momordica charantia, exhibits a diverse geographical presence across several key regions. In the Macaronesia region, it can be found specifically in Cape Verde. Its distribution extends significantly into West Tropical Africa, where it is documented in Benin. Furthermore, the species is present in the West Tropical African nations of Burkina and Gambia. Finally, its range continues through the West Tropical African territory of Ghana.

Region Area
Macaronesia Cape Verde
West Tropical Africa Benin
West Tropical Africa Burkina
West Tropical Africa Gambia
West Tropical Africa Ghana
West Tropical Africa Guinea-Bissau
West Tropical Africa Guinea
West Tropical Africa Ivory Coast
West Tropical Africa Liberia
West Tropical Africa Mali

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Ecology

The ecology of Momordica charantia is characterized by its ability to thrive across a broad altitudinal gradient, ranging from sea level up to a maximum elevation of 1500 m AMSL, with a mean elevational range of approximately 580 m AMSL. This plant is frequently found within the specialized ecosystem of the Floresta Ombrófila (also known as Floresta Pluvial), where it benefits from the high humidity and consistent moisture levels typical of rainforest environments. This distribution pattern suggests a high degree of adaptability to varying tropical altitudes while remaining fundamentally tied to the lush, wet conditions provided by ombrophilous forest habitats.

Elevational range max:
1500 m AMSL
Elevational range mean:
580 m AMSL
Elevational range min:
0 m AMSL
Habitat :
Floresta Ombrófila (= Floresta Pluvial)

Genetics

The genetics of Momordica charantia are characterized by a specific chromosomal arrangement and reproductive structure. The species possesses a chromosome number of 11, 22, which serves as a fundamental indicator of its genomic composition. Furthermore, the plant exhibits a diploid ploidy level of 2, establishing the baseline genetic complexity required for its biological development and the inheritance of its various medicinal properties.

Chromosome number :
11, 22
Ploidy :
2

Life history

The life history of Momordica charantia is characterized by an annual lifecycle, meaning it completes its entire reproductive process within a single growing season. As a plant that thrives in warm climates, its biological strategy is defined by its status as a therophyte, a life form where the plant survives the unfavorable season as a seed. This therophytic nature allows it to rapidly colonize available space once favorable environmental conditions return, utilizing its climbing vines to maximize light interception. Because it functions as both a therophyte in terms of its seasonal survival strategy and its overall structural classification, it relies on the rapid development from germination to seed production to ensure the continuation of its lineage before the onset of cold or dry periods.

Life form :
therophyte
Lifecycle :
annual

Morphology

The morphology of Momordica charantia is characterized by its growth form as a non-woody herb and specifically a forb. It functions as an independent, terrestrial plant that does not exhibit parasitic or epiphytic behavior, maintaining a strictly terrestrial lifestyle. As an obligatory climber, it utilizes a vine-like habit with a scandent shoot orientation to ascend its environment. The plant's physical stature is variable, with a minimum height of 0.5 m, a mean height of approximately 4 m, and a maximum potential height reaching up to 5 m.

Aquatic :
terrestrial
Climber :
vine
Climber :
obligatory
Epiphyte :
terrestrial
Growth form :
herb
Growth form :
forb
Parasite :
independent
Plant height max:
5 m
Plant height mean:
4 m
Plant height min:
0.5 m
Shoot orientation :
scandent
Woodiness :
non-woody

Physiology

The physiology of Momordica charantia is characterized by specific morphological adaptations and metabolic processes, particularly regarding its foliar structure and nutrient acquisition. The leaves exhibit a variable size range, with lengths typically spanning from a minimum of 3 cm to a maximum of 10 cm, and widths ranging between 4 cm and 8 cm. In terms of water storage strategies, the plant does not exhibit succulence, indicating a physiological reliance on standard transpiration and hydration methods rather than specialized fleshy tissues for moisture retention. Furthermore, the plant does not function as a nitrogen fixer, meaning it lacks the symbiotic relationship with nitrogen-fixing bacteria necessary to convert atmospheric nitrogen into a usable form, and instead relies on the uptake of nitrogen from the soil through its root system.

Leaf length max:
10 cm
Leaf length min:
3 cm
Leaf width max:
8 cm
Leaf width min:
4 cm
Nitrogen fixer :
no
Succulence :
no

Reproduction

The reproduction of Momordica charantia is characterized by a monoecious sexual reproductive system, featuring distinctive yellow flowers that facilitate pollination through a biotic syndrome, specifically relying on insects. Following successful pollination, the plant develops fleshy, capsule-type fruits that typically range in length from a minimum of 3 cm to a maximum of 12 cm. These fruits are dehiscent, meaning they split open to facilitate seed release. The seeds produced within the fruit vary in size and weight, with a minimum seed length of 8 mm and a maximum of 16 mm, and a seed volume that is consistently recorded at 380 mm³. In terms of mass, the seeds range from a minimum of 0.023 g to a maximum of 0.1667 g, with an average seed mass of approximately 0.0745875 g. Dispersal of the seeds is categorized as anthropochorous, often aided by human intervention.

Dehiscence :
dehiscent
Dispersal syndrome :
anthropochorous
Flower colour :
yellow
Fruit dryness :
fleshy
Fruit length max:
12 cm
Fruit length min:
3 cm
Fruit type :
capsule
Pollination syndrome :
insect
Pollination syndrome :
biotic
Reproduction sexual :
monoecious
Seed length max:
16 mm
Seed length min:
8 mm
Seed mass max:
0.1667 g
Seed mass mean:
0.0745875 g
Seed mass min:
0.023 g
Seed volume max:
380 mm³

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Momordica charantia has 5 reported plant parts identified across 45 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include fruit, seed, leaf, stem, root.

Plant parts reported in Momordica charantia
Plant part Supporting sources Consensus
Fruit 17 supporting sources ★★★★★
Seed 13 supporting sources ★★★★★
Leaf 11 supporting sources ★★★★★
Stem 3 supporting sources ★★☆☆☆
Root 1 supporting sources ★☆☆☆☆

Fruit

  1. Antioxidants (Basel, Switzerland)
  2. Journal of food biochemistry
  3. Chinese journal of natural medicines
  4. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
  5. Planta medica
View 12 additional sources
  1. Journal of ethnopharmacology
  2. Scientifica
  3. Medicinal chemistry (Shariqah (United Arab Emirates))
  4. FEBS letters
  5. Natural products and bioprospecting
  6. Indian journal of physiology and pharmacology
  7. Natural product research
  8. Journal of natural products
  9. BMC complementary and alternative medicine
  10. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
  11. Diabetes research and clinical practice
  12. The American journal of Chinese medicine

Seed

  1. Journal of ethnopharmacology
  2. Journal of food biochemistry
  3. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  4. FEBS letters
  5. Planta medica
View 8 additional sources
  1. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  2. Biochemical and biophysical research communications
  3. Biotechnology & genetic engineering reviews
  4. Natural product research
  5. International journal of cancer
  6. General pharmacology
  7. Bioinformation
  8. The American journal of Chinese medicine

Leaf

  1. Journal of parasitology research
  2. Medical sciences (Basel, Switzerland)
  3. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
  4. Scientifica
  5. African journal of medicine and medical sciences
View 6 additional sources
  1. Journal of ethnopharmacology
  2. Foods (Basel, Switzerland)
  3. Natural product research
  4. Veterinary world
  5. Journal of functional biomaterials
  6. Bratislavske lekarske listy

Stem

  1. Journal of natural products
  2. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
  3. Bratislavske lekarske listy

Root

  1. Bratislavske lekarske listy

Chemicals

Momordica charantia has 220 reported phytochemicals identified across 45 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Saponins, Charantin, quercetin, Momordicine I.

Chemicals reported in Momordica charantia
Chemical Supporting sources Consensus
Flavonoids 12 supporting sources ★★★★★
Saponins 7 supporting sources ★★★★☆
Charantin 6 supporting sources ★★★☆☆
quercetin 6 supporting sources ★★★☆☆
Momordicine I 5 supporting sources ★★★☆☆
SAPONIN 4 supporting sources ★★☆☆☆
triterpenoids 4 supporting sources ★★☆☆☆
CALCIUM 3 supporting sources ★★☆☆☆
Carotenoids 3 supporting sources ★★☆☆☆
Glycosides 3 supporting sources ★★☆☆☆

Flavonoids

  1. Journal of parasitology research
  2. Chinese journal of natural medicines
  3. Medicinal chemistry (Shariqah (United Arab Emirates))
  4. Veterinary parasitology
  5. Phytotherapy research : PTR
View 7 additional sources
  1. Pharmacognosy reviews
  2. Natural product research
  3. Cureus
  4. Cancers
  5. Journal of food science
  6. Applied biochemistry and biotechnology
  7. Frontiers in pharmacology

Saponins

  1. Current organic synthesis
  2. Journal of parasitology research
  3. Medical sciences (Basel, Switzerland)
  4. Chinese journal of natural medicines
  5. Pharmacognosy reviews
View 2 additional sources
  1. Pakistan journal of pharmaceutical sciences
  2. Phytomedicine : international journal of phytotherapy and phytopharmacology

Charantin

  1. Dr. Duke
  2. Plants (Basel, Switzerland)
  3. Chinese journal of natural medicines
  4. Pharmacognosy reviews
  5. Natural product research
View 1 additional sources
  1. Current medicinal chemistry

quercetin

  1. International journal of molecular sciences
  2. Journal of ethnopharmacology
  3. Veterinary parasitology
  4. Foods (Basel, Switzerland)
  5. World journal of experimental medicine
View 1 additional sources
  1. Applied biochemistry and biotechnology

Momordicine I

  1. Dr. Duke
  2. Pharmaceuticals (Basel, Switzerland)
  3. International journal of molecular sciences
  4. Food & function
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology

SAPONIN

  1. Journal of ethnopharmacology
  2. Pharmaceutical biology
  3. Planta medica
  4. The American journal of Chinese medicine

triterpenoids

  1. Journal of parasitology research
  2. Journal of ethnopharmacology
  3. Cancers
  4. Molecules (Basel, Switzerland)

CALCIUM

  1. Dr. Duke
  2. Frontiers in pharmacology
  3. Pakistan journal of pharmaceutical sciences

Carotenoids

  1. Current organic synthesis
  2. Heliyon
  3. Applied biochemistry and biotechnology

Glycosides

  1. Journal of parasitology research
  2. Pharmacognosy reviews
  3. Pakistan journal of pharmaceutical sciences

Activities

Momordica charantia has 457 reported activities identified across 45 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antidiabetic, Hypoglycemic, Antibacterial, Abortifacient.

Activities reported in Momordica charantia
Activity Supporting sources Consensus
Antioxidant 17 supporting sources ★★★★★
Antidiabetic 12 supporting sources ★★★★★
Hypoglycemic 12 supporting sources ★★★★★
Antibacterial 9 supporting sources ★★★★☆
Abortifacient 6 supporting sources ★★★☆☆
Antiviral 6 supporting sources ★★★☆☆
Anticancer 5 supporting sources ★★★☆☆
Antimicrobial 5 supporting sources ★★★☆☆
Antihyperglycemic 4 supporting sources ★★☆☆☆
Antitumor 4 supporting sources ★★☆☆☆

Antioxidant

  1. Dr. Duke
  2. International journal of molecular sciences
  3. Journal of agriculture and food research
  4. Foods (Basel, Switzerland)
  5. Journal of applied biomaterials & functional materials
View 12 additional sources
  1. Food & function
  2. BMC complementary and alternative medicine
  3. Pharmacognosy reviews
  4. Indian journal of experimental biology
  5. Journal of clinical biochemistry and nutrition
  6. African journal of traditional, complementary, and alternative medicines : AJTCAM
  7. Nutrients
  8. Veterinary world
  9. Neuropharmacology
  10. The Journal of pharmacy and pharmacology
  11. Tropical medicine and health
  12. Journal of biological regulators and homeostatic agents

Antidiabetic

  1. Dr. Duke
  2. Journal of ethnopharmacology
  3. The American journal of Chinese medicine
  4. Planta medica
  5. Scientifica
View 7 additional sources
  1. Food & function
  2. Pharmacognosy reviews
  3. Journal of clinical biochemistry and nutrition
  4. African journal of traditional, complementary, and alternative medicines : AJTCAM
  5. Nutrients
  6. Iranian biomedical journal
  7. Tropical medicine and health

Hypoglycemic

  1. Dr. Duke
  2. Chinese journal of integrative medicine
  3. International journal of molecular sciences
  4. The American journal of Chinese medicine
  5. Molecular and cellular biochemistry
View 7 additional sources
  1. Journal of natural products
  2. Pakistan journal of pharmaceutical sciences
  3. Journal of medicinal food
  4. Journal of agricultural and food chemistry
  5. Journal of ethnopharmacology
  6. Acta poloniae pharmaceutica
  7. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Antibacterial

  1. Dr. Duke
  2. Journal of dietary supplements
  3. The American journal of Chinese medicine
  4. Microorganisms
  5. Journal of applied biomaterials & functional materials
View 4 additional sources
  1. Pharmacognosy reviews
  2. Pakistan journal of pharmaceutical sciences
  3. Plant foods for human nutrition (Dordrecht, Netherlands)
  4. Experimental biology and medicine (Maywood, N.J.)

Abortifacient

  1. Dr. Duke
  2. Frontiers in pharmacology
  3. International journal of fertility
  4. Biochimica et biophysica acta
  5. General pharmacology
View 1 additional sources
  1. Phytotherapy research : PTR

Antiviral

  1. Dr. Duke
  2. Journal of dietary supplements
  3. Journal of agriculture and food research
  4. Pharmacognosy reviews
  5. BMC complementary and alternative medicine
View 1 additional sources
  1. Pakistan journal of pharmaceutical sciences

Anticancer

  1. Dr. Duke
  2. Journal of natural medicines
  3. Food & function
  4. Pharmacognosy reviews
  5. Current medicinal chemistry

Antimicrobial

  1. Scientifica
  2. Food & function
  3. Pharmacognosy reviews
  4. Biochemical genetics
  5. Plant foods for human nutrition (Dordrecht, Netherlands)

Antihyperglycemic

  1. Plants (Basel, Switzerland)
  2. Journal of ethnopharmacology
  3. Indian journal of experimental biology
  4. Plant foods for human nutrition (Dordrecht, Netherlands)

Antitumor

  1. Dr. Duke
  2. International journal of molecular sciences
  3. The American journal of Chinese medicine
  4. General pharmacology

Medicinal Uses

Momordica charantia has 111 reported medicinal uses identified across 45 scientific publications and several other databases. The most consistently reported uses include diabetes mellitus, cancer, antidiabetic, obesity, inflammation.

Most Reported Uses

Use Sources Consensus
diabetes mellitus Phytotherapy research : PTR (and other 12 sources) ★★★★★
cancer Chinese journal of natural medicines (and other 8 sources) ★★★★☆
antidiabetic Pakistan journal of pharmaceutical sciences (and other 7 sources) ★★★★☆
obesity World journal of gastroenterology (and other 6 sources) ★★★☆☆
inflammation Antioxidants (Basel, Switzerland) (and other 5 sources) ★★★☆☆
Diabetes mellitus Pharmaceuticals (Basel, Switzerland) (and other 4 sources) ★★☆☆☆
type 2 diabetes Journal of alternative and complementary medicine (New York, N.Y.) (and other 4 sources) ★★☆☆☆
COVID-19 International journal of molecular sciences (and other 3 sources) ★★☆☆☆
blood glucose BMC complementary and alternative medicine (and other 3 sources) ★★☆☆☆
breast cancer Cells (and other 3 sources) ★★☆☆☆

Preparations

Preparations Sources Consensus
extracts Phytotherapy research : PTR (and other 5 sources) ★★★☆☆
aqueous extracts Phytotherapy research : PTR (and other 4 sources) ★★☆☆☆
ethanol extract Phytotherapy research : PTR (and other 3 sources) ★★☆☆☆
ethanol extracts Brazilian journal of biology = Revista brasleira de biologia (and other 2 sources) ★☆☆☆☆
extract Puerto Rico health sciences journal (and other 2 sources) ★☆☆☆☆
fruit juice Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
methanol extract Journal of natural products (and other 2 sources) ★☆☆☆☆
seeds International journal of fertility (and other 2 sources) ★☆☆☆☆
vegetable Chinese journal of natural medicines (and other 2 sources) ★☆☆☆☆
50% methanol extract Nihon yakurigaku zasshi. Folia pharmacologica Japonica (and other 1 sources) ★☆☆☆☆