Mitrephora tomentosa

Mitrephora tomentosa · Accepted scientific name

Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆

Mitrephora tomentosa is a notable botanical species that has garnered significant interest within the field of pharmacological research. Scientific investigations have specifically focused on the biological potential of its bark preparations. Preliminary studies indicate that these extracts exhibit distinct cytotoxic activities against various cell lines. Such findings suggest that the plant may harbor valuable secondary metabolites capable of inhibiting cellular proliferation. Consequently, exploring the chemical profile of this species remains a priority for drug discovery efforts.

Quick facts
Synonyms
Kinginda Thorelii · Melodorum Arboreum · 8 more
Common names
Not available
Family
Annonaceae
Distribution
Not available
Plant Parts
Not available

Classification

Common Names

Mitrephora tomentosa is a fascinating botanical species known by several distinct names across different cultures. In Thailand, this plant is affectionately referred to by its common name, มะป่วน. Meanwhile, in Chinese-speaking regions, it is widely recognized as 银钩花. These diverse local names highlight the widespread geographical presence and cultural significance of the species. Understanding these various identities helps researchers and enthusiasts connect with the plant's unique heritage.

Sources: Catalogue of Life (COL)

Synonyms

Mitrephora tomentosa is a species characterized by a complex taxonomic history involving several recognized synonyms. Scientific literature identifies this plant under various names, including Kinginda thorelii and Kinginda tomentosa. It has also been historically categorized as Melodorum arboreum in different botanical contexts. Furthermore, the species is linked to the names Mitrephora bousigoniana and Mitrephora collinsiae. Understanding these shifting nomenclature relationships is essential for accurate botanical identification and research.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Mitrephora tomentosa is a fascinating member of the kingdom Plantae. This specific species belongs to the diverse genus Mitrephora, which is nested within the family Annonaceae. Taxonomically, it is classified under the order Magnoliales, reflecting its evolutionary lineage. Furthermore, the plant is categorized under the class Equisetopsida, placing it among the flowering plants. Understanding these botanical relationships provides essential insight into the plant's place within the natural world.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Magnoliales
Family Annonaceae
Genus Mitrephora

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Mitrephora tomentosa is a versatile plant species with a broad geographical presence across various Asian regions. Its distribution spans the temperate zones of China, specifically within the South-Central and Southeast provinces. The species is also found on the tropical island of Hainan, showcasing its adaptability to different climates. Beyond China, it extends into the tropical Indian Subcontinent, where it thrives in areas such as Assam. Furthermore, its range includes Bangladesh, cementing its status as a significant component of the regional flora.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Morphology

Mitrephora tomentosa is a self-supporting plant that takes the form of a sturdy tree. It is capable of reaching an impressive maximum height of 25 meters in the wild. This growth habit allows it to establish a significant presence within its natural ecosystem.

Sources: Global Inventory of Floras and Traits (GIFT)

Biological Activities

Mitrephora tomentosa has been identified as a significant source of bioactive compounds, particularly through the isolation of unique alkaloids from its bark. Researchers have successfully characterized several previously undescribed mitrephorines, including various dimeric aporphine and aristolactam-aporphine structures. These chemical constituents were rigorously analyzed using advanced techniques such as NMR, HRMS, and X-ray diffraction to confirm their complex architectures. Most notably, the study revealed that specific isolates possess potent cytotoxic activity against several human cancer cell lines, including MOLT-3 and HeLa. Importantly, these cytotoxic effects appear selective, as the active compounds did not demonstrate toxicity toward the MRC-5 normal cell line.

Compounds

Conditions

Preparations

Mitrephora tomentosa is prepared as bark to facilitate the isolation of various bioactive compounds. Researchers utilized the bark of this plant to extract several previously undescribed alkaloids, specifically mitrephorines A-E. These specialized aporphinoids and other cytotoxic substances are derived directly from the plant's bark material. The chemical structures of these isolated components were meticulously determined through diverse analytical techniques. Ultimately, the bark serves as the essential source for discovering these potent alkaloids with potential anticancer properties.

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