Cinchona pubescens
Melanopsidium nigrum · Accepted scientific name
Scientific literature: Very Extensive (274 studies) · ★★★★★
Cinchona pubescens, scientifically known as Melanopsidium nigrum, is a remarkable medicinal shrub native to the Andean forests. Renowned for its alkaloid-rich bark, it serves as a primary source of quinine. This potent botanical is traditionally utilized to treat malaria and various febrile conditions, playing a vital role in pharmacology.
Names and Synonyms
Common Names
- Cinchona pubescens
- Quinine
- Red Cinchona
- red Peruvian-bark
- redbark
- quina
Scientific Names
Accepted name
Melanopsidium nigrumSynonyms
- Cinchona pubescens
- Gardenia ferrea
- Rhyssocarpus pubescens
- Pleurocarpus decemfidus
Regional and Traditional Names
Spanish:
- Cinchona pubescens
- Cinchona cordifolia var. microcarpa
- Cinchona cordifolia var peruviana
- Cinchona cordifolia var. peruviana
- Cinchona pallescens var ovata
- Cinchona rugosa
- Cinchona decurrentifolia
- Cinchona rufinervis
- Cinchona ovata
- Cinchona rosulenta
- Cinchona cordifolia var. macrocarpa
- Flor nacional de ecuador
- Cinchona pelalba
- Cinchona platyphylla
- Cinchona succirubra var. conglomerata
- Cinchona tucujensis
- Cinchona succirubra
- Cascarilla
- Cinchona
- quino rojo
German:
- Cinchona pubescens
- Roter Chinarindenbaum
French:
- Quinquina rouge
- Cinchona pubescens
- quinquina rouge
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant, Melanopsidium nigrum, is classified within the kingdom Plantae and belongs to the phylum Streptophyta. It falls under the class Equisetopsida and the subclass Magnoliidae, specifically within the order Gentianaales. Furthermore, it is a member of the Rubiaceae family and is categorized under the genus Cinchona.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Gentianales |
| Family | Rubiaceae |
| Genus | Cinchona |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant is naturally found within specific regions of Brazil. Its geographical presence is primarily concentrated in the Northeast part of the country. Additionally, the species can be located throughout the Southeast region of Brazil. These two distinct areas represent its known native habitats. Therefore, its distribution is limited to these specific Brazilian territories.
| Region | Area |
|---|---|
| Brazil | Brazil Northeast |
| Brazil | Brazil Southeast |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Ecology
The ecology of Melanopsidium nigrum is characterized by its adaptation to specific Brazilian biomes, primarily occurring within the Cerrado (latu sensu) and Restinga ecosystems. This species exhibits a significant vertical distribution across varied landscapes, occupying a broad elevational range that spans from 600 m AMSL to a maximum of 3300 m AMSL. On average, the plant is found at an elevation of approximately 2100 m AMSL, reflecting its ability to thrive in diverse altitudinal gradients within its specialized habitats.
- Elevational range max:
- 3300 m AMSL
- Elevational range mean:
- 2100 m AMSL
- Elevational range min:
- 600 m AMSL
- Habitat :
- Cerrado (lato sensu), Restinga
Life history
The life history of Melanopsidium nigrum is characterized by its classification as a perennial organism, ensuring its persistence across multiple growing seasons. Structurally, the plant exhibits a phanerophyte life form, specifically categorized under the nanophanerophyte designation, which indicates that its regenerative buds are located on aerial shoots above the ground level. As an evergreen species, it maintains its foliage throughout the year rather than undergoing a seasonal shedding period, contributing to its steady physiological presence in its habitat. This combination of a long-lived lifecycle and persistent aerial growth patterns defines its biological strategy and environmental endurance.
- Deciduousness :
- evergreen
- Life form :
- nanophanerophyte
- Life form :
- phanerophyte
- Lifecycle :
- perennial
Morphology
The morphology of Melanopsidium nigrum is characterized by its growth form as a woody tree that functions as a self-supporting structure rather than a climber or liana. As a terrestrial plant, it does not exhibit aquatic or semiaquatic tendencies, nor does it function as an epiphyte or a parasite, maintaining an independent biological existence. The plant's stature is significant, with a height that typically ranges from a minimum of 5 meters to a maximum of 12 meters, although some measurements indicate a mean height of 15 meters and a maximum potential of up to 12 meters depending on environmental conditions. Its structural integrity is defined by its woody nature, supporting its development as a robust, self-supporting tree within its natural habitat.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- tree
- Parasite :
- independent
- Plant height max:
- 5 m
- Plant height max:
- 12 m
- Plant height mean:
- 15 m
- Woodiness :
- woody
Physiology
The physiology of Melanopsidium nigrum is characterized by specific metabolic processes and nutrient acquisition strategies that dictate its growth and survival in its natural habitat. Central to its physiological profile is its relationship with soil nutrients, specifically regarding its ability to transform atmospheric gases into usable forms for plant development. Regarding its capacity for nitrogen assimilation through symbiotic relationships, the plant is not a nitrogen fixer, meaning it lacks the specialized root nodules or microbial associations required to convert atmospheric nitrogen into ammonia. Consequently, its physiological processes rely on the uptake of nitrates or ammonium directly from the soil medium to support protein synthesis and enzymatic functions. This dependency on available soil nitrogen influences its metabolic rate and overall biomass production, as its physiological efficiency is strictly tethered to the nutrient availability of its immediate environment.
- Nitrogen fixer :
- no
Reproduction
The reproduction of Melanopsidium nigrum is characterized by a primarily biotic pollination syndrome, relying on living organisms rather than abiotic factors to facilitate the transfer of pollen. Within this reproductive framework, the plant utilizes an insect-mediated strategy to ensure genetic exchange. Specifically, the pollination process is heavily dependent on bees, which act as the key biological vectors for moving pollen between flowers. This targeted interaction between the plant and its insect pollinators ensures a successful fertilization cycle through these specialized biotic mechanisms.
- Pollination syndrome :
- insect
- Pollination syndrome :
- bee
- Pollination syndrome :
- biotic
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Melanopsidium nigrum has 1 reported plant parts identified across 1 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include stem.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Stem | 1 supporting sources | ★☆☆☆☆ |
Stem
- Lloydia
Chemicals
Melanopsidium nigrum has 48 reported phytochemicals identified across 1 scientific publications and several other databases. The most consistently reported chemicals include Quinine, Quinovic acid, (-)-Epicatechin, 1-Hydroxy-2-hydroxymethylanthraquinone, 2-hydroxy-1,3,4-trimethoxy-anthraquinone.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Quinine | 2 supporting sources | ★☆☆☆☆ |
| Quinovic acid | 2 supporting sources | ★☆☆☆☆ |
| (-)-Epicatechin | 1 supporting sources | ★☆☆☆☆ |
| 1-Hydroxy-2-hydroxymethylanthraquinone | 1 supporting sources | ★☆☆☆☆ |
| 2-hydroxy-1,3,4-trimethoxy-anthraquinone | 1 supporting sources | ★☆☆☆☆ |
| 3-EPIQUINAMINE | 1 supporting sources | ★☆☆☆☆ |
| 3-alpha,17-beta-Cinchophylline | 1 supporting sources | ★☆☆☆☆ |
| 3-beta,17-beta-Cinchophylline | 1 supporting sources | ★☆☆☆☆ |
| Alizarin | 1 supporting sources | ★☆☆☆☆ |
| Alizarin 1-methyl ether | 1 supporting sources | ★☆☆☆☆ |
Quinine
- Dr. Duke
- Journal of ethnopharmacology
Quinovic acid
- Dr. Duke
- Lloydia
(-)-Epicatechin
- Dr. Duke
1-Hydroxy-2-hydroxymethylanthraquinone
- Dr. Duke
2-hydroxy-1,3,4-trimethoxy-anthraquinone
- Dr. Duke
3-EPIQUINAMINE
- Dr. Duke
3-alpha,17-beta-Cinchophylline
- Dr. Duke
3-beta,17-beta-Cinchophylline
- Dr. Duke
Alizarin
- Dr. Duke
Alizarin 1-methyl ether
- Dr. Duke
Activities
Melanopsidium nigrum has 198 reported activities identified across 1 scientific publications and several other databases. The most consistently reported activities include Antimalarial, 5-Alpha-Reductase-Inhibitor, 5-Lipoxygenase-Inhibitor, ACE-Inhibitor, Abortifacient.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antimalarial | 2 supporting sources | ★☆☆☆☆ |
| 5-Alpha-Reductase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| 5-Lipoxygenase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| ACE-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| Abortifacient | 1 supporting sources | ★☆☆☆☆ |
| Aldose-Reductase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| Allelochemic | 1 supporting sources | ★☆☆☆☆ |
| Allergenic | 1 supporting sources | ★☆☆☆☆ |
| Alpha-Glucosidase-Inhibitor | 1 supporting sources | ★☆☆☆☆ |
| Amebicide | 1 supporting sources | ★☆☆☆☆ |
Antimalarial
- Dr. Duke
- Journal of ethnopharmacology
5-Alpha-Reductase-Inhibitor
- Dr. Duke
5-Lipoxygenase-Inhibitor
- Dr. Duke
ACE-Inhibitor
- Dr. Duke
Abortifacient
- Dr. Duke
Aldose-Reductase-Inhibitor
- Dr. Duke
Allelochemic
- Dr. Duke
Allergenic
- Dr. Duke
Alpha-Glucosidase-Inhibitor
- Dr. Duke
Amebicide
- Dr. Duke
Preparations
Melanopsidium nigrum has 2 reported preparations identified across 1 scientific publications and several other databases. The most consistently reported preparations include stem bark, stem wood.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Stem bark | 1 supporting sources | ★☆☆☆☆ |
| Stem wood | 1 supporting sources | ★☆☆☆☆ |
Stem bark
- Lloydia
Stem wood
- Lloydia