Mammea africana

Mammea africana · Accepted scientific name

Scientific literature: Very Sparse (3 studies) · ★☆☆☆☆

Mammea africana is a botanical species that has gained scientific interest due to its potent bioactive properties. Research focusing on the methanol extract of the plant's stem has revealed significant antimicrobial and antiproliferative activities. These biological effects are largely attributed to specific chemical compounds known as MAMMEA A and MAMMEA AA. Studies have demonstrated that these extracts are effective against diverse pathogens, including Campylobacter jejuni, Candida albicans, Clostridium difficile, and Enterococcus hirae. Consequently, these findings highlight the potential therapeutic value of this plant in combating various microbial threats.

Quick facts
Synonyms
Garcinia Golaensis · Ochrocarpos Africana · 3 more
Common names
Not available
Family
Calophyllaceae
Distribution
Asia-Temperate
Plant Parts
Stem

Classification

Common Names

Mammea africana, widely recognized by its common name the African mammea, is a fascinating botanical specimen. This plant belongs to a unique lineage that distinguishes it from other members of its genus. Understanding its specific nomenclature is essential for researchers studying its ecological role within its native habitat. As it grows, the species contributes significantly to the local biodiversity of the regions it inhabits. Exploring these botanical connections provides deeper insight into the complex relationships found within the natural world.

Sources: Catalogue of Life (COL)

Synonyms

Mammea africana is a botanical species recognized by several distinct scientific names across different taxonomic records. It is frequently identified by the synonym Garcinia golaensis, reflecting its complex classification history. Researchers may also encounter this plant listed as Mammea ebboro or Mammea gilletii in various botanical texts. Furthermore, the species is documented under the names Mammea giorgiana and Ochrocarpos africana. Understanding these various synonyms is essential for ensuring accuracy when studying the plant's diverse ecological relationships.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Mammea africana is a distinguished member of the kingdom Plantae. Within this vast biological realm, the species is classified under the class Equisetopsida. It belongs to the diverse order Malpighiales, which showcases its evolutionary connections. Further narrowing its identity, the plant is situated within the family Calophyllaceae. Finally, it is categorized under the specific genus Mammea to complete its botanical profile.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malpighiales
Family Calophyllaceae
Genus Mammea

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Mammea africana is a notable plant species with a diverse distribution spanning across the African continent. Its presence is recorded in East Tropical Africa, specifically within the borders of Uganda. The species also extends into South Tropical Africa, where it can be found in Angola. Furthermore, it maintains a significant footprint throughout West Tropical Africa. This widespread reach includes specific locations such as Benin, Ghana, and Guinea.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Morphology

Mammea africana is a robust, self-supporting tree that serves as a significant feature in its natural habitat. This species typically exhibits a sturdy growth form, allowing it to reach impressive proportions. While individual specimens generally range in height between 15.24 and 30.48 meters, certain exceptional trees can soar even higher. In some environments, the species may reach a maximum stature of 35 meters. This impressive vertical presence makes it a dominant element within its ecosystem.

Sources: Global Inventory of Floras and Traits (GIFT)

Biological Activities

Mammea africana is a plant widely distributed in tropical Africa that holds a significant place in traditional medicine. Recent scientific investigations have highlighted its potent antimicrobial properties, particularly through the isolation of the compound mammea A/AA. This specific isoprenylated coumarin has demonstrated high inhibitory activity against pathogenic bacteria such as Streptococcus pneumoniae and Clostridium difficile. Beyond its antibacterial effects, the plant also exhibits notable antiproliferative activity. Studies show that these cytotoxic properties are significant against both non-small cell lung cancer cell lines and normal fibroblast cell lines.

Compounds

Mammea africana is a plant widely distributed throughout tropical Africa and is frequently utilized in traditional medicine. Recent scientific investigations into its stem bark have successfully isolated a specific isoprenylated coumarin known as MAMMEA A/AA. This bioactive compound has demonstrated significant antibacterial properties, particularly against pathogens such as Streptococcus pneumoniae and Clostridium difficile. Furthermore, MAMMEA A/AA exhibits notable antiproliferative effects when tested against various cell lines. These findings highlight the medicinal potential of the compounds found naturally within Mammea africana.

Conditions

Mammea africana demonstrates significant biological activity against a variety of pathogenic organisms and cell lines. The plant's isolated compound, mammea A/AA, exhibits potent antiproliferative effects against the A549 non-small cell lung cancer cell line. Regarding bacterial infections, it shows high antibacterial activity against Campylobacter jejuni and Clostridium difficile. Furthermore, methanol extracts of the plant have proven effective in treating Candida albicans. The medicinal properties of Mammea africana also extend to the inhibition of Enterococcus hirae.

Preparations

Mammea africana is prepared as a methanol extract to investigate its various biological properties. Specifically, research has utilized a methanol extract from the stem bark to isolate active compounds like mammea A/AA. The plant is also processed into general extracts to evaluate its potential as a beta-lactamase inhibitor. These botanical extracts have been tested against various pathogenic bacteria and microbial strains to determine their efficacy. Through these different preparation methods, the medicinal potential of Mammea africana is systematically assessed.

Parts used

Mammea africana is a plant species widely distributed throughout tropical Africa that holds significant value in traditional medicine. Research has focused specifically on its stem bark to identify bioactive compounds with therapeutic potential. Through advanced extraction and chromatography techniques, scientists isolated a specific isoprenylated coumarin known as mammea A/AA. This compound demonstrated impressive antibacterial properties against pathogens such as Streptococcus pneumoniae and Clostridium difficile. Furthermore, the substance exhibited notable antiproliferative activity against both normal and lung cancer cell lines.