Ludwigia erecta

Ludwigia erecta · Accepted scientific name

Scientific literature: Very Sparse (2 studies) · ★☆☆☆☆

Ludwigia erecta is a botanical species that has garnered significant scientific interest due to its diverse therapeutic potential. Recent studies have focused extensively on its pharmacological profile, specifically highlighting its potent antimalarial and antiplasmodial activities. To investigate these properties, researchers typically utilize both water and methanol extracts to isolate its bioactive compounds. These preparations serve as the foundation for understanding how the plant can combat various stages of the malaria parasite. Consequently, the plant represents a promising subject in the ongoing search for natural medicinal alternatives.

Quick facts
Synonyms
Ludwigia Acuminata · Jussiaea Erecta Var. Sebana · 13 more
Common names
Not available
Family
Onagraceae
Distribution
Not available
Plant Parts
Not available

Classification

Common Names

Ludwigia erecta is a botanical species recognized by a diverse array of regional identifiers. Depending on the local tradition, it is frequently referred to by the common name Camarambaia-pequena. In other areas, people may simply call the plant Chananá or Clavito. It also carries the melodic names Girofle-ma and Girofle-mare within certain communities. These various names highlight the rich linguistic diversity used to describe this specific plant.

Sources: Catalogue of Life (COL)

Synonyms

Ludwigia erecta is a botanical species that has been identified through various taxonomic names throughout history. It is officially recognized as a synonym for Isnardia discolor, reflecting its complex classification. Furthermore, the plant is closely linked to Jussiaea acuminata, including its specific varieties such as var. latifolia and var. longifolia. Other historical designations also include Jussiaea altissima, illustrating the shifting nomenclature used by botanists. Understanding these synonym relationships is essential for accurate identification and scientific study of the species.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Ludwigia erecta is a distinctive species belonging to the vast kingdom Plantae. Within this biological kingdom, the plant is classified under the class Equisetopsida. It further resides in the order Myrtales, showcasing its specific evolutionary placement. The plant is a member of the Onagraceae family, which helps define its botanical characteristics. Finally, it is identified by its specific genus, Ludwigia, marking its unique position in the natural world.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Myrtales
Family Onagraceae
Genus Ludwigia

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Ludwigia erecta is a plant species primarily concentrated throughout various regions of the African continent. Its distribution spans from the East Tropical Africa region, specifically within Tanzania, to the vast reaches of Northeast Tropical Africa. Within these northern territories, the species can be found flourishing in Chad, Ethiopia, and Somalia. Furthermore, its presence extends across the landscape of Sudan and South Sudan. This wide geographic range highlights the plant's ability to adapt to diverse African environments.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Morphology

Ludwigia erecta is a self-supporting herb that exhibits a versatile range of physical dimensions. This plant can be found in various sizes, with some specimens measuring as little as 0.02 m in height. Conversely, other individuals may grow significantly larger, reaching a minimum height of 2 m. The species can eventually reach a maximum height of 3 m under optimal conditions. This adaptability in stature allows the plant to occupy diverse ecological niches.

Sources: Global Inventory of Floras and Traits (GIFT)

Biological Activities

Ludwigia erecta has emerged as a highly promising candidate in the search for new antimalarial treatments. According to research conducted by the Kenya Medical Research Institute, this plant species demonstrates exceptional antiplasmodial activity. Specifically, it showed potent results with an IC50 value of less than 1 μg/mL against the Plasmodium falciparum D6 strain. Furthermore, in vivo studies involving mice demonstrated significant chemosuppression at an oral dose of 100 mg/kg. These findings highlight the plant's potential as a foundation for future drug development in the fight against malaria.

Compounds

Conditions

Ludwigia erecta demonstrates significant potential as an antimalarial agent due to its high antiplasmodial activity. Research indicates that the plant effectively treats the Plasmodium falciparum D6 strain with an IC50 value of less than 1 μg/mL. Furthermore, the water and methanol extracts of this species show strong efficacy against chloroquine sensitive (D6) Plasmodium falciparum clones. The plant also proves effective in treating resistant (W2) Plasmodium falciparum clones, maintaining an IC50 of less than 5 μg/mL. These findings highlight the plant's ability to combat both sensitive and drug-resistant strains of the malaria parasite.

Preparations

Ludwigia erecta is prepared as both water and methanol extracts for pharmacological evaluation. These specific preparations were tested for their ability to combat malaria in various experimental models. The study found that both the water and methanol extracts of this plant exhibited high antiplasmodial activity. This activity was demonstrated against both chloroquine-sensitive and resistant clones of Plasmodium falciparum. Such findings highlight the potential effectiveness of these particular Ludwigia erecta extracts in treating malaria.

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