Lithraea molleoides

Lithraea molleoides · Accepted scientific name

Scientific literature: Very Sparse (3 studies) · ★☆☆☆☆

Lithraea molleoides is a plant species whose leaves have demonstrated significant therapeutic potential through various extraction methods. Research involving MeOH-CH2Cl2, aqueous, and dichloromethane extracts has highlighted its notable antimicrobial and antiulcer activities. These biological effects are attributed to key chemical constituents, including gallic acid, rutin, caffeic acid, and 1,3-dihydroxy-5-(tridec-4',7'-dienyl)benzene. Experimental studies have specifically examined its efficacy against pathogens such as Helicobacter pylori, Chlamydia pneumoniae, and Chlamydia trachomatis, as well as its impact on Caenorhabditis elegans. Consequently, this plant represents a promising subject for further pharmacological investigation into natural bioactive compounds.

Quick facts
Synonyms
Schinus Molleoides · Lithraea Gilliesii · 9 more
Common names
Not available
Family
Anacardiaceae
Distribution
Southern America
Plant Parts
Leaf

Classification

Common Names

Lithraea molleoides is a versatile plant species known by a diverse array of regional common names. Depending on the specific habitat or local dialect, it is frequently referred to as Aroeira branca or Aroeira-branca. In certain areas, the name Aroeira-brava is used to distinguish it from similar species. It is also commonly identified as Aroeira-da-capoeira when found growing in secondary forests. Finally, its presence in wetland environments often earns it the local designation of Aroeira-do-brejo.

Sources: Catalogue of Life (COL)

Synonyms

Lithraea molleoides is a complex species that is frequently identified through a variety of botanical synonyms. Taxonomists have historically linked this plant to several different names, including Lithraea aroeirinha and Lithraea gilliesii. It is also recognized in scientific literature under the labels Lithraea lorentzii and Lithraea molleoides var. lorentziana. Furthermore, the name Lithraea ternifolia has been utilized to describe specimens belonging to this group. Understanding these overlapping nomenclatures is essential for accurate botanical classification and study.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Lithraea molleoides belongs to the vast kingdom Plantae, representing a unique branch of the natural world. Within this kingdom, the species is classified under the class Equisetopsida and the order Sapindales. It is a distinguished member of the genus Lithraea, which helps define its specific botanical characteristics. Furthermore, this plant is a part of the Anacardiaceae family, sharing evolutionary ties with other related species. Through these hierarchical relationships, one can better understand the complex biological placement of this organism.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Sapindales
Family Anacardiaceae
Genus Lithraea

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Lithraea molleoides exhibits a remarkably wide geographical distribution that spans multiple continents. In Africa, the species is found throughout Northern Africa, specifically within the regions of Tunisia. Its presence extends into Northern America, where it inhabits Central Mexico and the southwestern United States, particularly in California. The plant also thrives in Southern America, establishing itself across various territories in Brazil. Specifically, its reach in South America covers both the Northeast and South regions of the Brazilian landscape.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Morphology

Lithraea molleoides is a self-supporting plant characterized by its distinct tree-like growth form. This species typically reaches a maximum height of 10 meters as it matures. Its structural stability allows it to thrive as a standalone feature within its natural habitat.

Sources: Global Inventory of Floras and Traits (GIFT)

Biological Activities

Lithraea molleoides is a medicinal plant from South America that has long been used to treat various digestive ailments. Recent scientific studies have confirmed that this species possesses significant antimicrobial activity against a wide range of tested microorganisms, including Helicobacter pylori. Furthermore, the plant demonstrates potent antiulcer properties, showing effectiveness in protecting against gastric ulcers induced by acid, alcohol, and other chemical agents. Research into its various extracts and isolated compounds, such as catechol and gallic acid, highlights their potential to inhibit the ulcer index significantly. These findings suggest that the identification of its active principles could provide valuable support for using the plant in the clinical treatment of digestive diseases.

Compounds

Lithraea molleoides is a medicinal plant traditionally used in South America to treat various digestive ailments. Research indicates that this plant contains several key bioactive compounds, including rutin and catechol. Furthermore, the plant is a source of important phenolic acids such as gallic acid, caffeic acid, and ferulic acid. These isolated principles contribute to the plant's significant gastroprotective and antimicrobial activities. Ultimately, the presence of these specific constituents supports the potential use of L. molleoides in treating digestive affections.

Conditions

Lithraea molleoides demonstrates significant gastroprotective properties by inhibiting the ulcer index caused by 0.2N NaOH and 0.6N HCl. The plant also shows effectiveness in treating gastric ulcers induced by 200mg/kg acetilsalicilic acid. Furthermore, isolated compounds from the plant exert a strong paralyzing effect on the nematode Caenorhabditis elegans. Finally, extracts of Lithraea molleoides exhibit inhibitory activity against Chlamydia pneumoniae.

Preparations

Lithraea molleoides is prepared as a MeOH-CH2Cl2 extract to isolate specific nematicidal alkylene resorcinols. This same plant species is also prepared as aqueous extracts for ethnopharmacological screenings to detect antiviral activity. Furthermore, Lithraea molleoides is prepared as a dichloromethane extract to investigate cytotoxic properties against human cancer cell lines. These various preparation methods allow researchers to identify diverse bioactive compounds within the plant. Each specific extraction technique targets different chemical profiles for distinct medicinal studies.

Parts used

Lithraea molleoides is an Argentine medicinal plant belonging to the Anacardiaceae family. Researchers focused their study on the specific chemical properties found within the leaf of this species. By using a dichloromethane extract from these leaves, they were able to isolate a new active 5-alkyl resorcinol. This newly identified compound, 1,3-dihydroxy-5-(tridec-4',7'-dienyl)benzene, demonstrated significant cytotoxic activity against several human tumoral cell lines. Such findings highlight the potential pharmacological importance of the chemical constituents located in the plant's foliage.