Lithospermum erythrorhizon

Red gromwell

Lithospermum erythrorhizon, commonly known as Shikon, is a perennial herb prized in traditional medicine. Its roots contain unique naphthoquinones, which impart a deep red color. Renowned for their potent anti-inflammatory, antimicrobial, and wound-healing properties, these bioactive compounds make it a vital ingredient in various dermatological and restorative treatments.

  • Scientific name: Lithospermum erythrorhizon
  • Family: Boraginaceae
  • Native range: Asia-Temperate

Taxonomical Classification

This plant belongs to the kingdom Plantae within the phylum Streptophyta and the class Equisetopsida. It is further classified under the subclass Magnoliidae in the order Boraginales and the family Boraginaceae. Finally, it is identified by its genus, Lithospermum.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Boraginales WCVP
Family Boraginaceae WCVP
Genus Lithospermum WCVP

Common Names

This plant, Lithospermum erythrorhizon, is known by various common names depending on the linguistic and regional context. In Japanese, it is referred to as ムラサキ (murasaki), while in Chinese, it is called 紫草 (zǐcǎo). Similarly, in the Lzh language, it is identified as 紫草. In Korean, the plant is known as 지치 (jichi), and in Estonian, it is called puna-rusujuur.
Language Common Name Source
ja ムラサキ Wikidata
zh 紫草 Wikidata
ko 지치 Wikidata
et puna-rusujuur Wikidata
lzh 紫草 Wikidata
zh-cn 紫草 Wikidata
zh-tw 紫草 Wikidata
fa گرومول بنفش Wikidata
en red gromwell Wikidata
en purple gromwell Wikidata

Distribution

This plant exhibits a wide geographical distribution across several key regions in Northern and Eastern Asia. In the vast expanse of Siberia, it can be found specifically in the areas of Chita and Yakutiya. Moving toward the Russian Far East, the species is also established in the Amur and Primorye regions. Its range extends significantly further south into the territory of China, particularly within the China South-Central region. Collectively, these locations highlight the plant's ability to thrive across diverse continental landscapes.

Region Area Source
Siberia Chita WCVP
Siberia Yakutiya WCVP
Russian Far East Amur WCVP
Russian Far East Primorye WCVP
China China South-Central WCVP
China Inner Mongolia WCVP
China Manchuria WCVP
China China North-Central WCVP
China China Southeast WCVP
Eastern Asia Japan WCVP

Plant Parts

This plant, known for its significant pharmacological properties, relies primarily on its specialized underground structures for medicinal use. The most vital components are the roots, which are harvested to obtain their potent bioactive compounds. Once processed, the dried root is often utilized in various traditional preparations to ensure stability and potency. These characteristic red roots are highly valued in herbal medicine, specifically because they serve as the primary source for concentrated red pigment extracts. Ultimately, the medicinal value of the root lies in these deep, colorful tissues that hold the essence of the plant's healing potential.
Total parts
9
Scientific sources
18
Plant Part Sources Confidence
roots 9 ★★★★☆
dried root 2 ★☆☆☆☆
root 1 ★☆☆☆☆
red roots 1 ★☆☆☆☆
red pigment extracts 1 ★☆☆☆☆
gromwell root 1 ★☆☆☆☆
green leaves/stems 1 ★☆☆☆☆
dried roots 1 ★☆☆☆☆
callus 1 ★☆☆☆☆

Chemicals

Lithospermum erythrorhizon has 28 reported phytochemicals identified across 69 scientific publications and several other databases. The most consistently reported chemicals include shikonin, acetylshikonin, Shikonin, alkannin, beta-hydroxyisovalerylshikonin.

Total chemicals
28
Scientific sources
69

Most Reported Compounds

Compound Sources Confidence
shikonin 21 ★★★★★
acetylshikonin 10 ★★★★★
Shikonin 8 ★★★★☆
alkannin 2 ★☆☆☆☆
beta-hydroxyisovalerylshikonin 2 ★☆☆☆☆
dihydroechinofuran 2 ★☆☆☆☆
lithospermic acid B 2 ★☆☆☆☆
p-hydroxybenzoic acid 2 ★☆☆☆☆
(22E)-Ergosta-4,6,8(14),22-tetraen-3-one 1 ★☆☆☆☆
3-geranyl-4-hydroxybenzoic acid 1 ★☆☆☆☆

Activities

Lithospermum erythrorhizon has 7 reported activities identified across 8 scientific publications and several other databases. The most consistently reported activities include Antiviral, Analgesic, Antibacterial, Antiinflammatory, Antimicrobial.

Total activities
7
Scientific sources
8

Most Reported Activities

Activity Sources Confidence
Antiviral 2 ★☆☆☆☆
Analgesic 1 ★☆☆☆☆
Antibacterial 1 ★☆☆☆☆
Antiinflammatory 1 ★☆☆☆☆
Antimicrobial 1 ★☆☆☆☆
Antioxidant 1 ★☆☆☆☆
Antithrombotic 1 ★☆☆☆☆

Medicinal Uses

Lithospermum erythrorhizon has 12 reported medicinal uses identified across 16 scientific publications and several other databases. The most consistently reported uses include cancer, inflammation, antiviral, infections, infectious diseases.

Total uses
12
Scientific sources
16

Most Reported Uses

Use Sources Confidence
cancer 4 ★★☆☆☆
inflammation 2 ★☆☆☆☆
antiviral 1 ★☆☆☆☆
infections 1 ★☆☆☆☆
infectious diseases 1 ★☆☆☆☆
lymphoproliferative disorders 1 ★☆☆☆☆
nonalcoholic fatty liver disease 1 ★☆☆☆☆
rheumatism 1 ★☆☆☆☆
tumor cell lines 1 ★☆☆☆☆
viral infections 1 ★☆☆☆☆