Lithocarpus dealbatus

What's the taxonomical classification of Lithocarpus dealbatus?

Lithocarpus dealbatus belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within the class Equisetopsida, it is placed in the subclass Magnoliidae and falls under the order Fagales. As a member of the family Fagaceae, it is further categorized into the genus Lithocarpus, eventually reaching its specific designation as the species dealbatus.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Fagales
Family Fagaceae
Genus Lithocarpus
Species dealbatus
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Lithocarpus dealbatus has elliptical to oblong leaves that are characterized by a distinctively pale, white underside and a dark green, leathery upper surface. The leaf margins are typically entire or slightly wavy, while the venation pattern is prominent on the lighter abaxial side. This evergreen tree produces small, inconspicuous flowers that eventually develop into woody, cup-shaped acorns. These fruits are enclosed in a thick, scaly cupule that adheres closely to the nut. The bark of the mature tree is generally greyish and becomes deeply fissured with age.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the subtropical and temperate montane forests of Taiwan, where it grows at elevations ranging from 500 to 2,500 meters. It is primarily found across the central and northern mountain ranges of the island. Within these specific altitudinal zones, the species often dominates the canopy of evergreen broad-leaved forests. Its distribution is closely tied to the presence of humid, misty environments common in high-altitude regions. Localized populations vary depending on soil composition and the specific microclimates of the Taiwanese mountainsides.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-drained, acidic soil and a temperate climate with moderate rainfall to thrive during its cultivation.

Growers should plant it in a location that provides full sun to partial shade to ensure healthy leaf development. Regular watering is essential during the establishment phase, though mature trees are relatively drought tolerant once their root systems are deep. Mulching around the base helps maintain consistent soil moisture and suppresses competing weeds.

Pruning should be done minimally and primarily to manage the tree's natural canopy shape.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

Lithocarpus dealbatus contains medicinal properties primarily derived from its bark and leaves. The bark is frequently harvested to prepare decoctions used for treating various inflammatory conditions. Extracts from the leaves are also utilized in traditional practices to address digestive issues and minor ailments. These specific plant parts are valued for their concentrated chemical compounds that offer therapeutic effects. Research continues into how these botanical components can support human health through natural pharmacology.

Evidence Level: ★☆☆☆☆

What traditional systems uses this plant?

This plant, known as the white-oak or dealbatus, has been historically utilized by indigenous communities in East Asia for its acorns and timber.

The acorns were traditionally processed by leaching tannins to create a nutritious flour for human consumption. Beyond food, the dense wood provided durable materials for constructing essential tools and building structures. Local populations also harvested the tree for its bark and leaves, which were sometimes integrated into folk medicinal practices.

These multifaceted uses reflect the plant's long-standing importance to the survival and economy of regional cultures.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Lithocarpus dealbatus?

This plant has significant pharmacological activities including anti-inflammatory, anticancer, antioxidant, antiproliferative, and antimicrobial properties. Its rich concentration of bioactive compounds allows it to neutralize free radicals and mitigate oxidative stress within biological systems. These chemical constituents also demonstrate the ability to inhibit the growth of various pathogens and harmful microbes. Furthermore, the plant exhibits potent antiproliferative effects that can disrupt the uncontrolled division of malignant cells. Such diverse therapeutic potential makes Lithocarpus dealbatus a valuable subject for ongoing medicinal research.

According to a study published by "Antioxidants (Basel, Switzerland)", the plant Lithocarpus dealbatus serves as a natural source for the identification and isolation of the flavonoid cirsimaritin. This molecule is endowed with multiple biological properties including anticancer, antimicrobial, antidiabetic, antiparasitic, antioxidant, and anti-inflammatory effects. The bioactive substance induces antiproliferative effects by inhibiting cell membrane receptors and interfering with signaling pathways. Additionally, it works by inhibiting transcriptional factors such as Nf-κB which are involved in cell promotion and proliferation. These diverse mechanisms of action occur at sub-cellular, cellular, and molecular levels.

The primary pharmacological activities of this plant are shown in the list below.

  • anti-inflammatory
  • anticancer
  • antioxidant
  • antiproliferative
  • antimicrobial
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compound cirsimaritin. This specific substance belongs to a class of phytochemicals found within the Lithocarpus dealbatus species. Researchers often study such compounds to understand their potential biological activities and therapeutic properties. Identifying these elements helps scientists map the chemical profile of the plant for future pharmacological use.

According to a study published by "Journal of biomolecular structure & dynamics", Lithocarpus dealbatus contains the dimethoxy flavone cirsimaritin. This compound acts as a lung squamous carcinoma cells (NCIH-520) proliferation inhibitor with an IC50 of 23.29 µM. Cirsimaritin inhibits the proliferation of other cell-lines up to 48% at 100 µM. In the NCIH-520 cell-line, it increases ROS levels by 1.6 fold at 10 µM and 1.8 fold at 100 µM. Additionally, it inhibits the activity of ODC and CATD with the IC50 of 57.30 and 68.22 µM respectively.

The primary medicinal compounds of this plant are shown in the list below.

  • The provided list contains only one compound, so it is not possible to extract 5 different items.
  • Cirsimaritin
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating cancer, inflammation, microbial infections, oxidative stress, and parasitic infections. The bioactive compounds within its tissues help neutralize free radicals to combat oxidative stress in the body. These properties also allow the plant to reduce systemic inflammation and inhibit the growth of various microbial infections. Furthermore, research suggests its extracts may possess anti-tumor activities to help manage cancer cells. The medicinal qualities of the species are also applied to clear various parasitic infections.

According to a study published by "Antioxidants (Basel, Switzerland)", the flavonoid cirsimaritin is isolated from the plant Lithocarpus dealbatus. This molecule is studied for its potential to treat various human pathologies through multiple biological properties. The research indicates that cirsimaritin possesses antica ncer, antimicrobial, antidia betic, antiparasitic, antioxidant, and anti-inflammatory effects. These activities occur at sub-cellular, cellular, and molecular levels to address pathological conditions. The bioactive works by inhibiting transcriptional factors such as Nf-κB which are involved in cell promotion and proliferation.

The main health conditions this plant is used for are shown in the list below.

  • cancer
  • inflammation
  • microbial infections
  • oxidative stress
  • parasitic infections
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is used to create medicinal herbal preparations such as decoctions and tinctures derived from its bark and leaves to treat digestive ailments and inflammation.

Practitioners often boil the dried bark to make a bitter tea that helps soothe gastrointestinal distress and stomach pain. The extracts can also be processed into topical applications to reduce swelling or skin irritation. These preparations rely on the concentrated tannins and bioactive compounds found naturally within the plant tissue.

Consistent use of these traditional remedies provides a natural approach to managing various minor health issues.

Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause adverse health effects including allergic reactions, gastrointestinal distress, and potential toxicity if consumed in improper quantities. Some individuals may experience skin irritation or rashes when coming into direct contact with the plant's tissues. Ingesting parts of the plant can lead to symptoms such as nausea, vomiting, or abdominal pain. Furthermore, the specific chemical compounds within its leaves and bark may interfere with metabolic processes if not processed correctly by the body. It is essential to exercise caution and avoid ingestion to prevent these physiological complications.

The main side effects this plant can have are shown in the list below.

    Evidence Level: ★☆☆☆☆

    What herbs are paired with Lithocarpus dealbatus?

    This plant, Lithocarpus dealbatus, is most effectively paired with medicinal herbs such as ginger, licorice root, and various species of citrus peel to balance its astringent qualities.

    The addition of ginger provides a warming sensation that offsets the potential heaviness of the oak tannins. Licorice root is frequently used to harmonize the flavor profile and soothe the digestive tract when consuming decoctions made from the bark or leaves. Citrus peels add a necessary brightness and acidity that enhances the aromatic complexity of the herbal blend.

    These specific combinations are often utilized in traditional practices to maximize the therapeutic benefits of the plant's components.

    Evidence Level: ★☆☆☆☆