Lasianthera africana

What's the taxonomical classification of Lasianthera africana?

Lasianthera africana belongs to the kingdom Plantae and is categorized within the phylum Streptophyta. It is classified under the class Equisetopsida and the subclass Magnoliidae, falling specifically into the order Aquifoliales. Within the family Stemonuraceae, this plant is placed in the genus Lasianthera, with its unique identity defined by its specific designation as the species africana.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Aquifoliales
Family Stemonuraceae
Genus Lasianthera
Species africana
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Lasianthera africana has a perennial herbaceous habit characterized by erect stems that typically reach heights of 10 to 40 centimeters. The leaves are arranged in an alternate pattern and feature long, linear to lanceolate blades with entire margins. Small, inconspicuous flowers are produced in axillary clusters, often appearing in shades of white or pale yellow. The reproductive structures include minute petals and stamens that are characteristic of the Euphorbiaceae family. These plants frequently develop small, fleshy fruits that contain seeds adapted for dispersal in their native habitats.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the arid and semi-arid regions of sub-Saharan Africa, specifically spanning across parts of East, Central, and Southern Africa. Its distribution is closely tied to sandy soils and dry savanna landscapes where it can thrive in low-moisture environments. Individual populations are often found in various habitats ranging from scrublands to open grasslands. The species is most commonly documented in countries such as Kenya, Tanzania, and South Africa. These geographical patterns reflect its biological adaptation to the continent's diverse tropical and subtropical climates.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-draining sandy soil and consistent partial shade to thrive in a subtropical climate.

You should water it regularly to maintain moisture without allowing the roots to sit in stagnant water. Providing organic compost during the planting phase helps establish a strong root system for the herb. It performs best when temperatures remain warm and protected from harsh frost.

Periodic pruning can encourage denser foliage and more robust growth throughout the season.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant uses its leaves for medicinal purposes to treat various ailments. These leaves are often crushed or prepared into decoctions to address specific health concerns. People utilize the plant's foliage to manage conditions such as digestive issues or skin irritations. The concentration of bioactive compounds within the leaf makes it a primary component in traditional remedies. Local practitioners rely on these specific parts to create effective herbal preparations.

According to a study published by "Heliyon", the leaves of Lasianthera africana are used as a traditional Nigerian medicinal plant for the treatment of ulcers, diarrhea, parasitic infections and diabetes. The flavonoid-rich fraction of these leaves contained total flavonoids measuring 281.05 ± 7.44 mg QE/g. Analysis of this fraction identified quercetin at 758983.6 mg/kg, isorrhamnetin at 197949.0 mg/kg, rutin at 17540.4 mg/kg, and luteolin at 126524.3 mg/kg. This leaf fraction displayed an in vitro antioxidant IC50 of 5.40 ± 0.00 μg/ml for scavenging DPPH. In studies involving 50 Wistar rats weighing 110-130 g, the leaf fraction administered at 3, 10, and 30 mg/kg body weight significantly (p < 0.05) improved renal function and normalized cardiac enzyme activities.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaf
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, Lasianthera africana, is utilized within Traditional African Medicine to treat various ailments including stomach pains, skin infections, and digestive issues. Practitioners often prepare decoctions or infusions from the leaves and roots to address these specific health concerns. In some regional customs, the plant is also applied topically as a poultice to soothe inflammation or heal wounds. Its historical use reflects a deep-seated reliance on local botanical knowledge for primary healthcare. This long-standing integration into indigenous healing practices highlights its significance in the ethnobotanical landscape of the continent.

According to a study published by "Heliyon", Lasianthera africana P. Beauv. (Icacinaceae) is a traditional Nigerian medicinal plant used for treatment of ulcers, diarrhea, parasitic infections and diabetes. The flavonoid-rich fraction of Lasianthera africana leaves contained total flavonoids measuring 281.05 ± 7.44 mg QE/g. Analysis indicated the presence of quercetin at 758983.6 mg/kg, isorrhamnetin at 197949.0 mg/kg, rutin at 17540.4 mg/kg, and luteolin at 126524.3 mg/kg. This plant fraction displayed an in vitro antioxidant IC50 of 5.40 ± 0.00 μg/ml when scavenging DPPH. These properties show its potential for developing alternative therapy for combating oxidative stress-related complications.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional African Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Lasianthera africana?

This plant has anti-diabetic, anti-diarrheal, anti-parasitic, anti-ulcer, and antioxidant pharmacological activities. These medicinal properties make the species highly valuable in traditional healing practices for managing various ailments. For instance, its ability to combat oxidative stress through antioxidant mechanisms helps protect cells from damage. The plant also demonstrates effectiveness in treating gastrointestinal issues such as diarrhea and stomach ulcers. Furthermore, its anti-parasitic and anti-diabetic qualities contribute to its broad range of therapeutic applications.

According to a study published by "Heliyon", Lasianthera africana is a traditional Nigerian medicinal plant used for the treatment of ulcers, diarrhea, parasitic infections and diabetes. The flavonoid-rich fraction of its leaves contains total flavonoids of 281.05 ± 7.44 mg QE/g, including quercetin (758983.6 mg/kg), rutin (17540.4 mg/kg), luteolin (126524.3 mg/kg), and isorrhamnetin (197949.0 mg/kg). This fraction displayed remarkable in vitro antioxidant property by scavenging the DPPH with an IC50 of 5.40 ± 0.00 μg/ml. When administered at 3, 10, and 30 mg/kg body weight, the extract significantly (p < 0.05) improved renal function and normalized cardiac enzyme activities in vivo. These activities demonstrate its potential for combating oxidative stress-related complications.

The primary pharmacological activities of this plant are shown in the list below.

  • anti-diabetic
  • anti-diarrheal
  • anti-parasitic
  • anti-ulcer
  • antioxidant
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains a flavonoid-rich fraction consisting of specific bioactive compounds including isorrhamnetin, luteolin, quercetin, and rutin. These chemical constituents contribute to the plant's significant therapeutic potential and pharmacological properties. The presence of these specific flavonoids suggests that the plant may possess antioxidant and anti-inflammatory activities. Researchers often study these particular molecules to understand the medicinal efficacy of the species. Such detailed chemical profiling is essential for identifying the exact mechanisms behind its traditional uses.

According to a study published by "Heliyon", Lasianthera africana is a traditional Nigerian medicinal plant used for the treatment of ulcers, diarrhea, parasitic infections, and diabetes. The flavonoid-rich fraction of its leaves contains total flavonoids quantified at 281.05 ± 7.44 mg QE/g. Analysis of this fraction revealed the presence of quercetin at 758983.6 mg/kg, isorrhamnetin at 197949.0 mg/kg, luteolin at 126524.3 mg/kg, and rutin at 17540.4 mg/kg. The fraction displayed remarkable antioxidant properties with an IC50 of 5.40 ± 0.00 μg/ml for scavenging DPPH. These compounds demonstrated the ability to improve renal function and normalize cardiac enzyme activities in vivo.

The primary medicinal compounds of this plant are shown in the list below.

  • isorrhamnetin
  • luteolin
  • quercetin
  • rutin
  • flavonoid-rich fraction
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating diabetes, diarrhea, inflammation, inflammatory disorders, and stomach ache. Traditional practitioners often prepare extracts from the plant to manage high blood sugar levels in patients with diabetes. It is also frequently administered to soothe digestive distress such as diarrhea and stomach ache. The medicinal properties of the species are highly valued for their ability to reduce systemic inflammation. Consequently, it serves as a vital resource for addressing various inflammatory disorder symptoms in local communities.

According to a study published by "Heliyon", Lasianthera africana P. Beauv. is a traditional Nigerian medicinal plant used for the treatment of ulcers, diarrhea, parasitic infections and diabetes. The study evaluated the effects of its flavonoid-rich fraction on renal and cardiac functions, specifically assessing the plant's impact on urea, creatinine, lactate dehydrogenase (LDH), and creatine kinase (CK) activities. In an in vivo evaluation involving 50 Wistar rats weighing 110-130 g, the plant extract was administered at doses of 3, 10, and 30 mg/kg body weight. The flavonoid-rich fraction contained total flavonoids of 281.05 ± 7.44 mg QE/g and displayed an IC50 of 5.40 ± 0.00 μg/ml for scavenging DPPH. These results showed the extract significantly (p < 0.05) improved renal function and normalized cardiac enzyme activities following CCl4 intoxication.

The main health conditions this plant is used for are shown in the list below.

  • diabbees
  • diarrhrea
  • inflammation
  • inflammatory disorder
  • stomach ache
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is used to create various medicinal preparations, including the flavonoid-rich fraction of Lasianthera africana leaves which provides potent antioxidant and anti-inflammatory benefits. Traditional healers often utilize decoctions and infusions derived from different parts of the plant to treat various ailments. Researchers have specifically focused on isolating bioactive compounds to understand their therapeutic potential in modern medicine. These botanical extracts are valued for their ability to combat oxidative stress within biological systems. Through careful processing, these herbal preparations serve as significant resources in ethnopharmacology.

According to a study published by "Heliyon", Lasianthera africana P. Beauv. is a traditional Nigerian medicinal plant used for the treatment of ulcers, diarrhea, parasitic infections and diabetes. The flavonoid-rich fraction of its leaves (LAFRF) contained total flavonoids measured at 281.05 ± 7.44 mg QE/g. Using UPLC-PDA-QTOF-ESI-MS/MS, the LAFRF fingerprint showed quercetin at 758983.6 mg/kg, isorhamnetin at 197949.0 mg/kg, rutin at 17540.4 mg/kg, and luteolin at 126524.3 mg/kg. This fraction displayed an in vitro antioxidant IC50 of 5.40 ± 0.00 μg/ml for scavenging DPPH. The study evaluated the effects of LAFRF at 3, 10, and 30 mg/kg body weight on various functions in 50 Wistar rats. The LAFRF significantly (p < 0.05) improved renal function and normalized cardiac enzyme activities in vivo.

The main herbal preparations of this plant are shown in the list below.

  • flavonoid-rich fraction of Lasianthera africana leaves
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause significant health side effects including gastrointestinal distress, skin irritation, and potential toxicity if ingested in large quantities. Consuming parts of the plant may lead to symptoms such as nausea, vomiting, or abdominal pain. When applied topically, the sap or leaves can trigger allergic reactions or localized redness on the skin. It is essential to exercise extreme caution because the specific chemical compounds within the plant can interfere with bodily functions. Avoiding direct contact and ingestion is the most effective way to prevent these adverse reactions.

The main side effects this plant can have are shown in the list below.

    Evidence Level: ★☆☆☆☆

    What herbs are paired with Lasianthera africana?

    This plant Lasianthes africana pairs most effectively with aromatic herbs like rosemary, thyme, and sage to enhance its subtle earthy base.

    Combining these woody herbs creates a layered flavor profile that balances the plant's natural bitterness. When used in infusions, adding mint or lemon balm can provide a refreshing contrast to its deep botanical notes. These specific combinations are often utilized in traditional wellness preparations to round out the sensory experience.

    Careful measurement of each pairing ensures that the potent qualities of the primary plant are not overwhelmed by the secondary herbs.

    Evidence Level: ★☆☆☆☆