creosote bush

Larrea tridentata · Accepted scientific name

Scientific literature: Very Extensive (522 studies) · ★★★★★

Creosote bush, scientifically known as Larrea tridentata, is a resilient evergreen shrub native to the arid landscapes of the American Southwest. Renowned for its distinctive, pungent aroma and medicinal properties, it has been used for centuries by indigenous cultures to treat skin ailments, inflammation, and various respiratory conditions.

Family
Zygophyllaceae
Native range
Northern America
Parts used
Aerial Parts · Leaves
Common names
Chaparral · Creosote · 2 more
Scientific synonyms
Guaiacum Mexicanum · Larrea Divaricata Var. Arenaria · 13 more

Names

Common Names

Regional and Traditional Names

Spanish:

  • gobernadora
  • hediondilla

German:

  • Kreosotbusch
  • Kreosotstrauch
  • Kreosotbusch

French:

  • Arbre à créosote
  • Créosotier

Scientific Names

Accepted name

Larrea tridentata

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it is ordered as Zygophyllales and placed in the family Zygophyllaceae. Finally, its specific taxonomic identity is defined by the genus Larrea.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Zygophyllales WCVP
Family Zygophyllaceae WCVP
Genus Larrea WCVP

Distribution

This plant, known as Larrea tridentata, is widely distributed across several key regions of the American West. In the Southwestern United States, it can be found extensively throughout the state of Arizona. Its presence also extends across the desert landscapes of California and Nevada. Additionally, this species thrives within the arid environments of Utah. Finally, its range reaches into the South-Central United States, specifically covering the state of New Mexico.

Region Area Source
Southwestern U.S.A. Arizona WCVP
Southwestern U.S.A. California WCVP
Southwestern U.S.A. Nevada WCVP
Southwestern U.S.A. Utah WCVP
South-Central U.S.A. New Mexico WCVP
South-Central U.S.A. Texas WCVP
Mexico Mexico Northeast WCVP
Mexico Mexico Gulf WCVP
Mexico Mexico Northwest WCVP
Mexico Mexico Southwest WCVP

Plant Parts

This plant, commonly known as creosote bush, possesses distinct morphological features that contribute to its medicinal properties. The stems are woody and often become gnarled and branched as the plant ages, providing a sturdy structural framework. Its leaves are small, resinous, and evergreen, coated in a waxy substance that helps the plant retain moisture in arid environments. Collectively, the aerial parts of Larrea tridentata are highly valued in traditional medicine, as the resins found on the surface of the foliage and stems contain bioactive compounds used for their antiseptic and anti-inflammatory effects.
Plant Part Sources Confidence
aerial parts Chemical & pharmaceutical bulletin (and other 1 sources) ★☆☆☆☆
leaves Journal of natural products (and other 1 sources) ★☆☆☆☆
stems Journal of natural products (and other 1 sources) ★☆☆☆☆

Chemicals

Larrea tridentata has 72 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include NORDIHYDROGUAIARETIC ACID, 1-HEXEN-3-ONE, 1-Hepten-3-one, 2-HEPTANONE, 2-Undecanone.

Most Reported Compounds

Compound Sources Confidence
NORDIHYDROGUAIARETIC ACID Journal of AOAC International (and other 2 sources) ★☆☆☆☆
1-HEXEN-3-ONE Dr. Duke (and other 1 sources) ★☆☆☆☆
1-Hepten-3-one Dr. Duke (and other 1 sources) ★☆☆☆☆
2-HEPTANONE Dr. Duke (and other 1 sources) ★☆☆☆☆
2-Undecanone Dr. Duke (and other 1 sources) ★☆☆☆☆
ALPHA-PINENE Dr. Duke (and other 1 sources) ★☆☆☆☆
ALUMINUM Dr. Duke (and other 1 sources) ★☆☆☆☆
Alanine Aminotransferase Archives of pathology & laboratory medicine (and other 1 sources) ★☆☆☆☆
Ash Dr. Duke (and other 1 sources) ★☆☆☆☆
BETA-PINENE Dr. Duke (and other 1 sources) ★☆☆☆☆

Activities

Larrea tridentata has 418 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Anticancer, Antiviral, Lipoxygenase-Inhibitor, (-)-Chronotropic.

Most Reported Activities

Activity Sources Confidence
Antioxidant Dr. Duke (and other 5 sources) ★★★☆☆
Anticancer Dr. Duke (and other 3 sources) ★★☆☆☆
Antiviral Dr. Duke (and other 2 sources) ★☆☆☆☆
Lipoxygenase-Inhibitor Dr. Duke (and other 2 sources) ★☆☆☆☆
(-)-Chronotropic Dr. Duke (and other 1 sources) ★☆☆☆☆
(-)-Inotropic Dr. Duke (and other 1 sources) ★☆☆☆☆
ACE-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
AChE-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
AP-1-Inhibitor Dr. Duke (and other 1 sources) ★☆☆☆☆
Acaricide Dr. Duke (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Larrea tridentata has 16 reported medicinal uses identified across 3 scientific publications and several other databases. The most consistently reported uses include fulminant hepatic failure, HIV-1, Trichinella spiralis, cancer, cholelithiasis.

Most Reported Uses

Use Sources Confidence
fulminant hepatic failure JAMA (and other 2 sources) ★☆☆☆☆
HIV-1 Journal of chromatography. A (and other 1 sources) ★☆☆☆☆
Trichinella spiralis Plants (Basel, Switzerland) (and other 1 sources) ★☆☆☆☆
cancer Journal of traditional and complementary medicine (and other 1 sources) ★☆☆☆☆
cholelithiasis Revista de gastroenterologia de Mexico (and other 1 sources) ★☆☆☆☆
cirrhosis Archives of internal medicine (and other 1 sources) ★☆☆☆☆
contact dermatitis Journal of the American Academy of Dermatology (and other 1 sources) ★☆☆☆☆
edema Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 1 sources) ★☆☆☆☆
hepatitis Archives of internal medicine (and other 1 sources) ★☆☆☆☆
human immunodeficiency virus Journal of traditional and complementary medicine (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Confidence
methanol extracts Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 2 sources) ★☆☆☆☆
Cellulose hydrogel films enriched with LT BioMed research international (and other 1 sources) ★☆☆☆☆
LT cellulose films BioMed research international (and other 1 sources) ★☆☆☆☆
Larrea tridentata tincture Journal of alternative and complementary medicine (New York, N.Y.) (and other 1 sources) ★☆☆☆☆
botanical dietary supplement Archives of internal medicine (and other 1 sources) ★☆☆☆☆
botanical extracts Journal of alternative and complementary medicine (New York, N.Y.) (and other 1 sources) ★☆☆☆☆
cellulose hydrogels BioMed research international (and other 1 sources) ★☆☆☆☆
ethanolic extracts International journal of molecular sciences (and other 1 sources) ★☆☆☆☆