Lagopsis supina

What's the taxonomical classification of Lagopsis supina?

Lagopsis supina belongs to the kingdom Plantae and is classified within the phylum Streptophyta. As a member of the class Equisetopsida and the subclass Magnoliidae, it is further categorized under the order Lamiales. It falls within the family Lamiaceae, specifically nested in the genus Lagopsis, with the specific epithet supina identifying the species.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Lamiales
Family Lamiaceae
Genus Lagopsis
Species supina
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Lagopsis supina has a prostrate, creeping growth habit characterized by slender, spreading stems that form dense mats along the ground. The leaves are small, typically elliptic or lanceolate in shape, and are arranged alternately along the stems. These leaves feature entire margins and a somewhat fleshy texture that aids in moisture retention. The plant produces small, inconspicuous flowers that emerge from the axils of the leaves. Its root system is shallow but efficient at anchoring the sprawling stems to the substrate.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the arid and semi-arid regions of North Africa, specifically ranging from Morocco and Algeria through to Egypt. It is primarily found in sandy or rocky substrates within desert ecosystems and dry scrublands. These populations often inhabit low-lying areas where seasonal moisture allows for sporadic growth. The species is also documented across parts of the Middle East, extending into territories such as Saudi Arabia and Jordan. Its distribution is strictly limited by its requirement for hot, dry climates and well-draining soils.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-drained, sandy soil and full sun exposure to thrive in a garden setting.

Growers should provide regular watering during the initial establishment phase but must allow the substrate to dry between sessions to prevent root rot. Because it is a drought-tolerant species, it performs best in arid or Mediterranean climates where moisture levels are naturally low. Mulching around the base helps maintain moderate soil temperatures while discouraging weed competition.

Pruning dead foliage occasionally will encourage more vigorous growth and maintain a compact shape.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Lagopsis supina is used medicinally primarily through its whole aerial parts, including the leaves and stems, which are often prepared as decoctions or infusions.

These herbal components are traditionally utilized to address various ailments, particularly those involving inflammation or digestive issues. The bioactive compounds found within the foliage are believed to provide therapeutic benefits when processed correctly. Practitioners often harvest the fresh greenery to ensure the highest concentration of medicinal properties.

By utilizing these specific parts, traditional medicine seeks to harness the plant's natural healing potential.

Evidence Level: ★☆☆☆☆

What traditional systems uses this plant?

This plant Lagoopsis supina is utilized in Traditional Chinese Medicine as a herb for clearing heat and resolving toxicity in various topical applications. Historical records suggest it has been applied to treat skin inflammations and minor wounds due to its perceived cooling properties. Practitioners often prepared decoctions or poultices from the plant to address specific ailments related to internal heat imbalances. These traditional methods rely on the plant's specific biological characteristics to manage localized discomfort. Such long-standing medicinal practices highlight the role of the species in regional herbal pharmacopeias.

According to a study published by "Journal of ethnopharmacology", Lagopsis supina has been used as a traditional medicinal herb for centuries in China. In folk medicine, the plant is utilized for diuretic activities, anti-inflammatory activities, and for promoting blood circulation and removing blood stasis. Modern pharmacological investigations have demonstrated that Lagopsis supina possesses antioxidative, myocardioprotective, and improvements in blood and lymphatic microcirculation. In a study using 30 male Sprague-Dawley rats, an ethanol extract of Lagopsis supina was administered orally at 460 mg/kg once daily for 7 successive days. This treatment resulted in a significant increase in total urine output (p < 0.01) and a significant decrease in the expression levels of AQP-1, 2, and 3 proteins. These findings embody the traditional Chinese medicine application principle of Huo xue li shui.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional Chinese Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Lagopsis supina?

This plant has anti-inflammatory, antioxidative, and circulatory properties that facilitate the improvement in blood and lymphatic microcirculation. By enhancing these fluid movements, it serves as an effective agent for promoting blood circulation throughout the body. The plant also plays a vital role in removing blood stasis to prevent stagnation in the vessels. These combined pharmacological activities support overall vascular health and cellular protection.

According to a study published by "Journal of ethnopharmacology", Lagopsis supina has been used in folk medicine for anti-inflammatory, diuretic, and blood circulation promoting activities. Modern pharmacological investigation has shown that the plant possesses antioxidative, myocardioprotective, and improvements in blood and lymphatic microcirculation. In a study involving 30 male Sprague-Dawley rats divided into 3 groups of 10 animals, an oral administration of 460 mg/kg of LS once daily for 7 successive days was tested. This treatment resulted in a significant increase in total urine output (p < 0.01) and a decrease in the expression levels of AQP-1, 2 and 3 proteins. Furthermore, LS treatment decreased levels of Ang II, ADH and ALD (p < 0.05 or p < 0.01) while increasing ANP levels (p < 0.05).

The primary pharmacological activities of this plant are shown in the list below.

  • anti-inflammatory
  • antioxidative
  • improvement in blood and lymphatic microcirculation
  • promoting blood circulation
  • removing blood stahesis
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compounds apiagenin-7-O-(6''-(E)-p-coumaroyl)-beta-D-galactopyranoside, beta-sitosterol, daucosterol, oleanolic acid, and palmitic acid. These specific phytochemicals contribute to the complex chemical profile found within its tissues. The presence of sterols like beta-sitosterol and daucosterol suggests potential biological activities related to cellular stability. Furthermore, the inclusion of oleanolic acid and various fatty acids like palmitic acid highlights its diverse metabolic makeup. These constituents work together to define the therapeutic possibilities of the species.

According to a study published by "Yao xue xue bao = Acta pharmaceutica Sinica", two new compounds were isolated from Lagopsis supina using column chromatography of silica gel and Sephadex LH-20. These chemical constituents were identified through spectral analysis. The first compound is apigenin-7-O-(6"-(E)-p-coumaroyl)-beta-D-galactopyranoside (I). The second compound is apigenin-7-O-(3",6"-di-(E)-p-coumaroyl)-beta-D-galactopyranoside (II).

The primary medicinal compounds of this plant are shown in the list below.

  • apigenin-7-O-(6"-(E)-p-coumaroyl)-beta-D-galactopyranoside
  • beta-sitosterol
  • daucosterol
  • oleanolic acid
  • palmitic acid
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for the treatment of blood microcirculation improvement, blood stasis, diuresis, edema, and lymphatic microcirculation improvement. It works by stimulating the flow of blood to prevent the stagnation known as blood stasis. The medicinal properties also help to reduce swelling by promoting diuresis and alleviating edema. Furthermore, the plant supports the body by facilitating lymphatic microcirculation improvement. These combined actions assist in restoring healthy fluid balance and circulation throughout the vascular system.

According to a study published by "Journal of ethnopharmacology", Lagopsis supina is used in folk medicine for promoting blood circulation, removing blood stasis, anti-inflammatory, and diuretic activities. Modern pharmacological investigations have shown that it possesses antioxidative, myocardioprotective, and improvements in blood and lymphatic microcirculation. In a study involving 30 male Sprague-Dawley rats divided into 3 groups of 10 animals, an oral dose of 460 mg/kg of L. supina was administered once daily for 7 successive days. The treatment resulted in a significant increase in total urine output (p < 0.01) and a significant decrease in the levels of Ang II, ADH, and ALD (p < 0.05 or p < 0.01), while ANP levels increased (p < 0.05). Furthermore, the plant exerts its diuretic effect by inhibiting the expression of aquaporin-1, 2, and 3 proteins in a rat model of traumatic blood stasis.

The main health conditions this plant is used for are shown in the list below.

  • blood microcirculation improvement
  • blood staist
  • diuresis
  • edema
  • lymphatic microcirculation improvement
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is Lagopsis supina, which is utilized in medicinal herbal preparations to harness its specific bioactive properties. One of the most common methods for utilizing this species is the creation of an ethanol extract. This specific preparation process allows for the efficient concentration of soluble phytochemicals that may provide therapeutic benefits. These extracts are often studied for their potential pharmacological effects in traditional medicine. Researchers continue to investigate how different solvent concentrations impact the efficacy of these herbal preparations.

According to a study published by "BioMed research international", Lagopsis supina has been used as a traditional Chinese medicine and an agent for diuresis in China for centuries. The study evaluated the ethanol extract of Lagopsis supina (LS) and its 4 fractions (LSA, LSB, LSC, and LSD) in normal rats. Administration of LS-H, LS-M, LSB-H, and LSC-L significantly increased urine output, while urine excretion was significantly reduced after treatment with LSB-L. Urine Na+ excretion was remarkably increased with LS-H, LS-M, LSA-H, LSA-L, LSB-H, LSC-L, and LSD-L, whereas urine K+ excretion was significantly increased after administration of LS-H and LSB-H. Within 24 h, LS and its 4 fractions did not change the urine and serum TNF-alpha and IL-6 levels in normal rats.

The main herbal preparations of this plant are shown in the list below.

  • ethanol extract
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can provide therapeutic benefits through its anti-inflammatory activities, diuretic effect, and improvement in blood and lymphatic microcirculation. These pharmacological properties allow the species to assist in reducing swelling and managing fluid retention within the body. By stimulating the lymphatic system, it helps to enhance the movement of fluids through the circulatory network. The reduction of inflammation further supports the overall recovery of affected tissues. Consequently, these combined physiological actions make it a subject of interest for various medicinal applications.

According to a study published by "Journal of ethnopharmacology", Lagopsis supina was administered orally at 460 mg/kg once daily for 7 successive days to 10 rats in a study involving 30 male Sprague-Dawley rats. The ethanol extract of Lagopsis supina caused a significant increase in total urine output with a p < 0.01. Treatment led to a decrease in Na+ and Ca2+ levels, the Na+/K+ value, and the levels of Ang II, ADH, and ALD with p < 0.05 or p < 0.01. Additionally, the ANP level increased with p < 0.05, while the Cl- level and pH value in the urine increased. The diuretic effect of Lagopsis supina is achieved by significantly decreasing the expression levels of AQP-1, 2, and 3 proteins.

The main side effects this plant can have are shown in the list below.

  • anti-inflammatory activities
  • diuretic effect
  • improvement in blood and lymphatic microcirculation
Evidence Level: ★★★☆☆

What herbs are paired with Lagopsis supina?

This plant Lagopsis supina is most effectively paired with aromatic herbs such as lavender, rosemary, and sage to enhance its subtle floral profile.

These companions provide a robust scent that balances the delicate structure of the plant in a garden setting. When used in culinary or medicinal contexts, pairing it with mint or lemon balm can brighten its earthy undertones. Such combinations are often chosen to create a more complex sensory experience during harvest.

Selecting the right herb partner ensures that the unique characteristics of Lagopsis supina are highlighted rather than overshadowed.

Evidence Level: ★☆☆☆☆