White walnut

Juglans cinerea · Accepted scientific name

Scientific literature: Very Extensive (424 studies) · ★★★★★

White walnut, scientifically known as Juglans cinerea, is a deciduous tree native to North America, valued for its medicinal properties. Historically, its bark has been utilized in traditional remedies to treat skin conditions and digestive issues. Today, it remains a significant subject of study for its complex chemical compounds.

Family
Not available
Native range
Europe
Parts used
Not available
Common names
Not available
Scientific synonyms
Not available

Names and Synonyms

Scientific Names

Accepted name

Juglans cinerea

Regional and Traditional Names

German:

  • Butternuss
  • Butter-Walnuss

French:

  • Noyer cendré

Sources: Wikidata

Distribution

This plant exhibits a broad distribution across several distinct regions of the European continent. In Northern Europe, its presence can be noted within the borders of Denmark. Moving into Middle Europe, the species is found throughout both Germany and Poland. Its range extends into Southeastern Europe, specifically covering parts of Romania. Finally, the distribution reaches the Baltic States located in Eastern Europe.

Region Area
Northern Europe Denmark
Middle Europe Germany
Middle Europe Poland
Southeastern Europe Romania
Eastern Europe Baltic States
Central Asia Tadzhikistan
Caucasus North Caucasus
Caucasus Transcaucasus
Eastern Canada New Brunswick
Eastern Canada Ontario

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Juglans cinerea is characterized by its status as a perennial species, meaning it lives for many years and undergoes repeated cycles of growth and reproduction. As a long-lived woody plant, it follows a developmental trajectory that begins with seed germination, typically in the spring, followed by an establishment phase where the seedling develops a robust taproot system to support its future stature. The plant progresses through several years of vegetative growth, accumulating biomass and developing a complex canopy before reaching reproductive maturity. Once mature, it engages in seasonal cycles of flowering and fruit production, characterized by the development of inconspicuous flowers and the eventual maturation of its characteristic nut-like drupes. Throughout its perennial lifespan, the plant must navigate seasonal environmental shifts, entering periods of dormancy during colder months to conserve energy and protect its tissues, before resuming active growth in the subsequent growing seasons.

Lifecycle :
perennial

Morphology

The morphology of Juglans cinerea is characterized by its growth form as a woody tree, typically reaching an average height of 27.24 meters. As a self-supporting organism, it does not exhibit climbing habits such as lianas or vines, and it functions as an independent species rather than a parasite. The plant is strictly terrestrial in its habitat, lacking aquatic or epiphytic tendencies, and maintains a robust, woody structure throughout its development.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
tree
Parasite :
independent
Plant height mean:
27.24 m
Woodiness :
woody

Physiology

The physiology of Juglans cinerea is characterized by a metabolic framework driven by a C3 photosynthetic pathway, which involves the direct fixation of atmospheric carbon dioxide by the enzyme RuBisCO during the Calvin cycle. This C3 mechanism dictates the plant's water-use efficiency and gas exchange patterns, as it relies on the opening of stomata to facilitate CO2 uptake, making the species sensitive to photorespiration under high-temperature or drought-stressed conditions. Beyond its carbon fixation strategy, the plant's physiological processes are heavily influenced by the production of secondary metabolites, most notably juglone, which serves as a biochemical defense mechanism through allelopathy. The metabolic regulation of these phenolic compounds is integrated into its overall physiological response to environmental stressors and competition within its ecosystem.

Photosynthetic pathway :
C3

Reproduction

The reproduction of Juglans cinerea is characterized by a diverse range of dispersal syndromes, including anemochorous, zoochorous, autochorous, hydrochorous, and unspecialized methods, which allow the species to colonize various habitats. The seeds produced by this plant exhibit notable variation in weight, with a recorded minimum seed mass of 11.5478 g and a maximum seed mass of 15.152 g. On average, the seed mass is approximately 14.390795 g, reflecting the energetic investment required for the successful establishment of new offspring through its various dispersal mechanisms.

Dispersal syndrome :
zoochorous
Seed mass max:
15.152 g
Seed mass mean:
14.390795 g
Seed mass min:
11.5478 g

Sources: Global Inventory of Floras and Traits (GIFT)

Chemicals

Juglans cinerea has 72 reported phytochemicals identified across 0 scientific publications and several other databases. The most consistently reported chemicals include ALUMINUM, ANTIMONY, ARSENIC, Ash, BARIUM.

Chemicals reported in Juglans cinerea
Chemical Supporting sources Consensus
ALUMINUM 1 supporting sources ★☆☆☆☆
ANTIMONY 1 supporting sources ★☆☆☆☆
ARSENIC 1 supporting sources ★☆☆☆☆
Ash 1 supporting sources ★☆☆☆☆
BARIUM 1 supporting sources ★☆☆☆☆
BORON 1 supporting sources ★☆☆☆☆
BROMINE 1 supporting sources ★☆☆☆☆
CADMIUM 1 supporting sources ★☆☆☆☆
CALCIUM 1 supporting sources ★☆☆☆☆
CESIUM 1 supporting sources ★☆☆☆☆

ALUMINUM

  1. Dr. Duke

ANTIMONY

  1. Dr. Duke

ARSENIC

  1. Dr. Duke

Ash

  1. Dr. Duke

BARIUM

  1. Dr. Duke

BORON

  1. Dr. Duke

BROMINE

  1. Dr. Duke

CADMIUM

  1. Dr. Duke

CALCIUM

  1. Dr. Duke

CESIUM

  1. Dr. Duke

Activities

Juglans cinerea has 345 reported activities identified across 0 scientific publications and several other databases. The most consistently reported activities include 5-Alpha-Reductase-Inhibitor, ACE-Inhibitor, AP-1-Inhibitor, ATPase-Inhibitor, Acarifuge.

Activities reported in Juglans cinerea
Activity Supporting sources Consensus
5-Alpha-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆
ACE-Inhibitor 1 supporting sources ★☆☆☆☆
AP-1-Inhibitor 1 supporting sources ★☆☆☆☆
ATPase-Inhibitor 1 supporting sources ★☆☆☆☆
Acarifuge 1 supporting sources ★☆☆☆☆
Acnegenic 1 supporting sources ★☆☆☆☆
Adjuvant 1 supporting sources ★☆☆☆☆
Allelochemic 1 supporting sources ★☆☆☆☆
Allergenic 1 supporting sources ★☆☆☆☆
Alpha-Reductase-Inhibitor 1 supporting sources ★☆☆☆☆

5-Alpha-Reductase-Inhibitor

  1. Dr. Duke

ACE-Inhibitor

  1. Dr. Duke

AP-1-Inhibitor

  1. Dr. Duke

ATPase-Inhibitor

  1. Dr. Duke

Acarifuge

  1. Dr. Duke

Acnegenic

  1. Dr. Duke

Adjuvant

  1. Dr. Duke

Allelochemic

  1. Dr. Duke

Allergenic

  1. Dr. Duke

Alpha-Reductase-Inhibitor

  1. Dr. Duke

Conditions

Juglans cinerea has 5 reported investigations on conditions identified across 0 scientific publications and several other databases. The most consistently reported conditions include Aspergillus fumigatus, Candida albicans, Cryptococcus neoformans, Klebsiella pneumoniae, Saccharomyces cerevisiae.

Conditions investigated for Juglans cinerea
Condition Supporting sources Consensus
Aspergillus fumigatus 1 supporting sources ★☆☆☆☆
Candida albicans 1 supporting sources ★☆☆☆☆
Cryptococcus neoformans 1 supporting sources ★☆☆☆☆
Klebsiella pneumoniae 1 supporting sources ★☆☆☆☆
Saccharomyces cerevisiae 1 supporting sources ★☆☆☆☆

Aspergillus fumigatus

  1. Journal of ethnopharmacology

Candida albicans

  1. Journal of ethnopharmacology

Cryptococcus neoformans

  1. Journal of ethnopharmacology

Klebsiella pneumoniae

  1. Journal of ethnopharmacology

Saccharomyces cerevisiae

  1. Journal of ethnopharmacology

Preparations

Juglans cinerea has 2 reported preparations identified across 0 scientific publications and several other databases. The most consistently reported preparations include bark extract, bark extract from Juglans cinerea.

Preparations reported for Juglans cinerea
Preparation Supporting sources Consensus
Bark extract 1 supporting sources ★☆☆☆☆
Bark extract from juglans cinerea 1 supporting sources ★☆☆☆☆

Bark extract

  1. Journal of ethnopharmacology

Bark extract from juglans cinerea

  1. Journal of ethnopharmacology