Jatropha multifida

What's the taxonomical classification of Jatropha multifida?

Jatrophia multifida belongs to the kingdom Plantae and is categorized under the phylum Streptophyta. Within this lineage, it is classified in the class Equisetopsida and the subclass Magnoliidae. Following the taxonomic hierarchy further, it is placed in the order Malpighiales and the family Euphorbiaceae. Finally, the plant is identified by its genus, Jatropha, and its specific species, multifida.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malpighiales
Family Euphorbiaceae
Genus Jatropha
Species multifida
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Jatrophia multifida has deeply lobed, pinnatifid leaves that are typically three to five inches long and characterized by narrow, finger-like segments. The plant grows as a perennial shrub or small tree, often reaching heights of up to six feet with woody stems. Its flowers are small and clustered in terminal cymes, displaying a mix of colors ranging from pale yellow to reddish-pink. The fruit is a three-lobed capsule that splits open upon maturity to reveal seeds. These distinct morphological features allow the species to thrive in various tropical environments.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the tropical regions of Mexico and Central America, spanning from southern Mexico through countries like Guatemala, Honduras, and Costa Rica. It thrives primarily in lowland areas characterized by warm, humid climates and seasonal rainfall. While its natural range is restricted to these neotropical zones, it has been introduced to various other tropical environments globally for ornamental purposes. Because it prefers well-drained soils and avoids frost, its distribution is limited to frost-free latitudes. Consequently, you will find it scattered in botanical gardens and tropical landscapes across much of the equatorial belt.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-draining soil, full sun exposure, and a tropical or subtropical climate to thrive during its cultivation.

Growers should provide consistent moisture while ensuring the roots do not sit in stagnant water to prevent rot. Once established, the species is relatively drought-tolerant and can withstand periods of low rainfall. Regular fertilization with a balanced liquid formula during the growing season will encourage more vibrant red blooms.

Pruning the branches occasionally helps maintain a bushy shape and prevents the shrub from becoming overly leggy.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Jatropha multifida utilizes its leaves, latex, roots, seeds, and fruits for various medicinal purposes. The leaves are often crushed or boiled to treat skin inflammations and wounds. A milky latex is extracted from the plant to address certain dermatological conditions. Roots are frequently decocted into teas to help manage gastrointestinal issues. Both the seeds and the fruits contain bioactive compounds that are traditionally applied to treat infections or topical ailments.

According to a study published by "F1000Research", the Betadine plant, Jatrophia multifida L., has many functions involving the sap, leaves, fruit and seeds. The stem sap contains saponins, tannins, flavonoids and labaditin, which act as an antimicrobial. In a laboratory study, stem sap extract was tested at concentrations of 25%, 50%, 75%, and 100%. The 50% concentration produced the highest inhibition zone of 12.725 ± 0.2500 mm. In contrast, the 100% concentration resulted in the lowest inhibition zone of 8.675 ± 0.5620 mm.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaves
  • latex
  • root
  • seeds
  • fruit
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, known as coral plant, is utilized within Traditional African Medicine to treat various ailments such as skin infections, wounds, and gastrointestinal issues. Various cultures have historically employed the milky latex from its leaves and stems as a topical treatment for dermatological conditions. In some regions, decoctions made from the plant are ingested in carefully controlled doses to address parasitic infections or stomach pains. Beyond medicinal uses, certain indigenous practices have historically incorporated the plant into rituals or as a component in local herbal preparations. The diverse applications of Jatrophas multifida reflect a long history of ethnobotanical knowledge passed down through generations.

According to a study published by "Life (Basel, Switzerland)", Jatrophia multifida L. is commonly used in Benin's traditional medicine due to its therapeutic benefits. The extracts demonstrated bactericidal effects with Concentration Minimally Bactericidal values ranging from 22.67 mg/mL to 47.61 mg/mL. The ethanolic variant showed an IC50 value of 0.72 ± 0.03 mg/mL for DPPH radical scavenging activity. The methanolic extract registered 46.23 ± 1.10 µgEAA/g in ferric ion reduction. Additionally, the water-ethanolic extract achieved an ABTS reduction score of 0.49 ± 0.11 mol ET/g and a highest albumin denaturation inhibition rate of 97.31 ± 0.35% at a concentration of 1000 µg/mL.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional African Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Jatropha multifida?

This plant has demonstrated significant pharmacological activities including anti-inflammatory, antibacterial, antifungal, antimicrobial, and antioxidant properties. Scientific studies indicate that its phytochemical constituents work to neutralize free radicals and reduce oxidative stress within biological systems. The plant also exhibits a broad spectrum of antimicrobial effects that can effectively inhibit the growth of various pathogenic bacteria and fungi. Furthermore, its ability to suppress inflammatory responses makes it a subject of interest for treating swelling and tissue irritation. These diverse biological actions suggest that the species holds considerable potential for developing new therapeutic agents.

According to a study published by "Life (Basel, Switzerland)", Jatropha multifida L. exhibits various biological activities including antimicrobial, antioxidant, and anti-inflammatory properties. The extracts demonstrated bactericidal effects with Concentration Minimally Bactericidal values ranging from 22.67 mg/mL for S. aureus and C. albicans to 47.61 mg/mL for E. coli. Regarding antioxidant capacity, the ethanolic extract showed a DPPH radical scavenging IC50 value of 0.72 ± 0.03 mg/mL, while the methanolic extract registered 46.23 ± 1.10 µgEAA/g in ferric ion reduction. Additionally, the water-ethanolic extract achieved an ABTS reduction score of 0.49 ± 0.11 mol ET/g. This same water-ethanolic extract also showcased the highest albumin denaturation inhibition rate of 97.31 ± 0.35% at a concentration of 1000 µg/mL.

The primary pharmacological activities of this plant are shown in the list below.

  • anti-inflammatory
  • antibacterial
  • antifungal
  • antimicrobial
  • antioxidant
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains various medicinal compounds including 2-Hydroxybenzoic acid, apigenin-apiosyl-glucoside, luteolin-galactoside, o-Coumaroylquinic acid, and various flavonoids. These bioactive substances contribute to the complex chemical profile that characterizes the species. The presence of specific flavonoids and glycosides suggests potential therapeutic properties within its extracts. Research into these individual elements helps scientists understand the biological activity inherent in the plant. Each of these chemical constituents plays a unique role in the overall medicinal potential of the organism.

According to a study published by "Life (Basel, Switzerland)", Jatropha multifida L. contains phenolic and flavonoid compounds including 2-Hydroxybenzoic acid, o-Coumaroylquinic acid, Apigenin-apiosyl-glucoside, and luteolin-galactoside. The extracts demonstrated bactericidal effects with Concentration Minimally Bactericidal (CMB) values ranging from 22.67 mg/mL to 47.61 mg/mL. The ethanolic variant showed a DPPH radical scavenging IC50 value of 0.72 ± 0.03 mg/mL, while the methanolic extract registered 46.23 ± 1.10 µgEAA/g in ferric ion reduction. Additionally, the water-ethanolic extract achieved an ABTS reduction score of 0.49 ± 0.11 mol ET/g. This same water-ethanolic extract also showcased the highest albumin denaturation inhibition rate of 97.31 ± 0.35% at a concentration of 1000 µg/mL.

The primary medicinal compounds of this plant are shown in the list below.

  • 1. 2-Hydroxybenzoic acid
  • 2. Apigenin-apiosyl-glucoside
  • 3. apocynin
  • 4. labaditin
  • 5. luteolin-galactoside
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating antimalarial, antimicrobial, and antitumor conditions, as well as managing fungal infections of the skin and infected wounds. Its medicinal properties allow it to combat various pathogens that cause systemic illness. When applied topically, the plant helps clear skin ailments caused by fungal growth. It is also frequently utilized in traditional medicine to prevent the spread of infection in open or wounded areas. Researchers continue to study its biological activity to better understand these therapeutic effects.

According to a study published by "BMC complementary and alternative medicine", the stems of Jatropha multifida Linn. have been used in traditional medicine for the treatment of various diseases. This plant has been reported to possess antimicrobial, antimalarial, and antitumor activities. Research involving 118 medicinal plants from Myanmar identified that extracts from the stems of Jatropha multifida Linn. show anti-influenza activity against the influenza A H1N1 virus. Specifically, H2O extracts promoted the survival of MDCK cells infected with the influenza A H1N1 virus. The H2O, EtOAc, and CHCl3 extracts inhibited influenza A virus H1N1 infection, with the H2O extract possessing the strongest inhibitory effect. Furthermore, the EtOAc, Hex, and CHCl3 extracts inhibited the growth of the influenza A H1N1 virus, while the CHCl3 extract demonstrated the strongest activity in MDCK cells.

The main health conditions this plant is used for are shown in the list below.

  • antimalarial
  • antimicrobial
  • antitumor
  • fungal infections of the skin
  • infected wounds
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is used to create medicinal preparations including latex, methanol extracts, chloroform extract, and raw sap. The raw sap and milky latex are often applied topically to treat skin conditions or wounds. Scientists also utilize methanol extracts to isolate specific bioactive compounds for pharmacological study. Additionally, the chloroform extract serves as a specialized medium for identifying potent antimicrobial properties within the plant tissues. These various forms allow for different methods of administering the plant's natural chemical constituents.

According to a study published by "Journal of ethnopharmacology", the latex of Jatropha multifida is traditionally applied in the treatment of infected wounds. Researchers isolated a polymer characterized as a proanthocyanidin from the latex to explain this medicinal use. This specific polymer inhibits the classical pathway (CP) activation of the complement cascade in human serum. However, the alternative pathway (AP) activation remains relatively insensitive to the polymer. This selective inhibition occurs due to the depletion of Ca2+ but not Mg2+ from the incubation medium.

The main herbal preparations of this plant are shown in the list below.

  • latex
  • methanol extracts
  • Chloroform extract
  • raw sap
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause severe health issues through its demonstrated cytotoxicity and geno-toxicity in biological systems. The presence of specific bioactive compounds triggers cell death by disrupting essential metabolic processes within living tissues. Furthermore, the chemical components can induce genetic damage, leading to mutations or instability in DNA structures. Such toxic effects pose significant risks if the plant is ingested or handled without proper precautions. Consequently, the biological impact of these substances necessitates extreme caution regarding its medicinal or topical use.

According to a study published by "Basic & clinical pharmacology & toxicology", Jatropha multifida was found to exhibit genotoxicity. All plant extracts investigated in the study showed high cytotoxic effects in almost all tests. The study evaluated 12 extracts for their potential to cause toxicity and pharmacokinetic interactions. While 75% of the herbal extracts showed potent competition with CYP3A4, 2D6, 2C9 and 2C19, specific data for Jatropha multifida regarding these enzymes was not isolated from the group. These findings indicate the possibility of potential medicinal plant-antiretroviral interactions.

The main side effects this plant can have are shown in the list below.

  • cytotoxicity
  • genotoxicity
Evidence Level: ★★★☆☆

What herbs are paired with Jatropha multifida?

This plant is most commonly paired with aloe vera, ginger, and peppermint to enhance its medicinal properties in topical applications.

When used in traditional herbalism, the sap of Jatropha multifida is often blended with aloe to soothe skin irritations and promote wound healing. Ginger is frequently integrated into formulations to provide a warming effect that stimulates circulation around the application site. Peppermint is another frequent companion used to create a cooling sensation that helps alleviate localized inflammation.

These specific combinations are carefully balanced to mitigate the plant's potency while maximizing its therapeutic benefits.

Evidence Level: ★☆☆☆☆