Isodon lophanthoides
Isodon lophanthoides · Accepted scientific name
Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆
Isodon lophanthoides is a botanical species known for containing the distinctive chemical compound lophanic acid. Medicinal applications of this plant primarily focus on utilizing the leaf to treat various ailments. When prepared as an aqueous extract, it is traditionally used to address gastrointestinal issues such as dysentery and enteritis. Furthermore, the plant has been employed in managing conditions like cholecystitis and necrosis. This combination of chemical properties and therapeutic uses makes it a subject of significant pharmacological interest.
- Synonyms
- Plectranthus Striatus Var. Gerardianus · Plectranthus Lophanthoides · 2 more
- Common names
- Not available
- Family
- Lamiaceae
- Distribution
- Not available
- Plant Parts
- Leaf
Classification
Common Names
Isodon lophanthoides is a distinctive plant recognized by several unique names across different linguistic traditions. In Vietnam, it is locally referred to by the common name Đẳng nha sọc. Moving to East Asia, the species is known in Japanese contexts as 線紋香茶菜. Similarly, it is identified by the Chinese name 线纹香茶菜, reflecting its botanical characteristics. Understanding these diverse names helps researchers and enthusiasts identify the plant throughout its varied geographic range.
Sources: Catalogue of Life (COL)
Synonyms
Isodon lophanthoides is a botanical species that has been identified through various taxonomic classifications over time. In scientific literature, it is frequently referred to by its synonym, Hyssopus lophanthoides. The plant is also recognized under the name Plectranthus lophanthoides, reflecting different historical groupings. Furthermore, its complex classification history includes associations with Plectranthus striatus var. gerardianus. Finally, the name Rabdosia lophanthoides serves as another established synonym for this specific plant.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Isodon lophanthoides is a fascinating specimen that belongs to the vast kingdom Plantae. Within this biological realm, the plant is classified under the class Equisetopsida. It further falls into the order Lamiales, showcasing its specific evolutionary lineage. As a member of the Lamiaceae family, it shares characteristics with many well-known aromatic herbs. Ultimately, this species is defined by its placement within the genus Isodon.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Lamiales |
| Family | Lamiaceae |
| Genus | Isodon |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Isodon lophanthoides exhibits a diverse geographic range that spans across several distinct regions of Asia. Within the temperate zones of China, this species is widely distributed through the North-Central, South-Central, and Southeast provinces. Its presence also extends into the unique high-altitude landscapes of Tibet. Moving into more tropical climates, the plant can be found across the Indian Subcontinent, specifically within the Assam region. This broad distribution highlights the plant's ability to adapt to various ecological niches across the continent.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Isodon lophanthoides is characterized by its distinct growth form as a herbaceous plant. This species is entirely self-supporting, allowing it to maintain its structure within its natural habitat.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Compounds
Isodon lophanthoides serves as a significant botanical source for various bioactive chemical compounds. Recent chemical analyses of its leaves have successfully isolated a variety of diterpenoids. Among these identified substances is lophanic acid, which was found alongside other known diterpenoids. Researchers also utilized spectroscopic evidence to identify a new compound named 11 beta-hydroxyisopimara-8,15-diene-3-one within the plant. These findings highlight the complex chemical profile inherent to this specific species.
Conditions
Isodon lophanthoides aqueous extract demonstrates a protective effect against acute hepatic injury by regulating specific serum biomarkers. Research indicates that the plant effectively treats elevated levels of ALP in the blood. It also functions to decrease ALT, which is a key indicator of liver damage. Furthermore, the extract treats AST and T-Bil to help mitigate the effects of hepatic injury. Finally, Isodon lophanthoides assists in the reduction of TBA levels in the serum.
Preparations
Isodon lophanthoides var. gerardianus is prepared as an aqueous extract to evaluate its medicinal properties. This specific aqueous extract was administered to rats via gastric perfusion to study its biological impact. Researchers utilized varying dosages of the extract to assess its efficacy against liver damage. The study demonstrated that the aqueous preparation of the plant could successfully reduce serum levels of ALT, AST, ALP, and total bilirubin. Ultimately, the results confirmed that the Isodon lophanthoides aqueous extract provides a protective effect against acute hepatic injury induced by carbon tetrachloride.
Parts used
Isodon lophanthoides serves as a significant source of various chemical compounds for botanical research. Specifically, the leaves of this plant contain unique diterpenoids that are essential to its chemical profile. During recent investigations, researchers successfully isolated a new diterpenoid alongside known substances like lophanic acid. The structural identity of this new compound was confirmed to be 11 beta-hydroxyisopimara-8,15-diene-3-one. Such findings highlight the importance of studying the leaf components of this species for drug discovery.