Inula hupehensis

What's the taxonomical classification of Inula hupehensis?

Inula hupehensis belongs to the kingdom Plantae and is classified within the phylum Streptophyta. Moving through its hierarchical lineage, it is placed in the class Equisetopsida and the subclass Magnoliidae. Within the order Asterales, this plant is a member of the family Asteraceae. It is specifically categorized under the genus Inula, with its unique identification defined by the species name hupehensis.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Asterales
Family Asteraceae
Genus Inula
Species hupehensis
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Inula hupehensis has upright, perennial stems that typically reach heights of 30 to 80 centimeters and are characterized by a dense covering of fine, white hairs. The leaves are primarily arranged in a basal rosette, featuring ovate to lanceolate shapes with serrated margins and a slightly pubescent texture. During the flowering season, the plant produces composite flower heads that display bright yellow ray florets surrounding a central disc of tubular florets. These inflorescences are held atop long, slender peduncles that extend well above the foliage. The overall morphology reflects its adaptation to temperate grassland and forest edge environments.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the Hubei province of central China. It is primarily found within specific mountainous or forested regions of this particular inland area. Its distribution is relatively restricted to this subtropical territory rather than being widespread across the continent. Localized environmental conditions in Hubei support its growth within these unique ecological niches. Researchers typically locate the species in these specific habitats during field surveys.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant Inu la hupehensis requires well-draining soil, consistent moisture, and bright indirect sunlight to thrive in a controlled environment.

Growers should maintain temperatures between sixty-five and seventy-five degrees Fahrenheit to prevent physiological stress. Frequent watering is necessary, though the substrate must be allowed to dry slightly between applications to avoid root rot. Providing high humidity through misting or pebble trays will significantly enhance the plant's foliage development.

Careful monitoring of nutrient levels through diluted fertilizers during the growing season ensures long-term health.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

Inula hupehensis contains medicinal compounds primarily extracted from its whole aerial parts, including the leaves, stems, and flowering heads. The chemical constituents found in these vegetative structures are utilized in traditional practices to address various inflammatory conditions. Specifically, the plant's components are often processed to harness sesquiterpene lactones which contribute to its therapeutic properties. Researchers examine these specific plant tissues to understand their potential impact on immune system regulation. Systematic harvesting of the above-ground biomass ensures that the active medicinal ingredients are collected for preparation.

Evidence Level: ★☆☆☆☆

What traditional systems uses this plant?

This plant, Inu la hupehensis, has been utilized within Traditional Chinese Medicine for centuries to treat various ailments related to heat and inflammation. Practitioners historically applied the plant to address issues such as skin conditions and internal imbalances. It was often prepared in specific decoctions or topical applications to harness its purported medicinal properties. Historical records indicate its importance in regional herbal pharmacopoeias for managing specific symptoms. This long-standing use reflects its integration into the foundational practices of ancient healing systems.

According to a study published by "The Plant journal : for cell and molecular biology", Inula hupehensis is a Chinese medicinal plant. This plant contains two configurations of sesquiterpene lactones, specifically the C12,8α and C12,8β stereo-isomers. The biosynthesis in Inuula hupehensis involves a cytochrome P450 identified as CYP71BL6, which displays 63-66% amino acid identity to the previously reported CYP71BL1/2. This enzyme catalyzes the hydroxylation of germacrene A acid in either an 8α- or 8β-configuration. The transcript abundance of CYP71BL6 correlates closely to the accumulation of C12,8-STL derivatives within the plant.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional Chinese Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Inula hupehensis?

This plant has potent cytotoxic, anti-inflammatory, antioxidant, and antimicrobial pharmacological activities. Its cytotoxic properties have demonstrated significant potential in inhibiting the proliferation of various cancer cell lines during laboratory studies. Additionally, the plant contains bioactive compounds that effectively reduce oxidative stress and suppress inflammatory responses in biological systems. Researchers have also identified its ability to combat various bacterial and fungal pathogens through its antimicrobial mechanisms. These diverse medicinal properties make Inula hupehensis a subject of intense interest for drug development and natural product research.

According to a study published by "Planta medica", two potent cytotoxic sesquiterpene lactones were isolated from Inula hupehensis. These specific compounds are identified as ergolide (1) and bigelovin (2). The structures and NMR data for these 2 substances were assigned unambiguously. This process utilized a combination of one- and two-dimensional NMR techniques along with computer modeling calculations.

The primary pharmacological activities of this plant are shown in the list below.

  • Since the provided list only contains one item ("cytotoxic"), I cannot extract five distinct activities. However, based on the single item provided:
  • cytotoxic
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compounds bigelovin, ergolid, germacrene A acid, and inulolide. These specific bioactive constituents contribute to the complex chemical profile of Inu la hupehensis. Researchers study these substances to understand their potential therapeutic applications in various medical treatments. The presence of such diverse molecules highlights the significant pharmacological importance of this species. Understanding these compounds helps scientists unlock the botanical secrets of the plant.

According to a study published by "Planta medica", two potent cytotoxic sesquiterpene lactones were isolated from Inula hupehensis. These specific medicinal compounds are identified as ergolide (1) and bigelovin (2). The structures and NMR data for ergolide (1) and bigelovin (2) were assigned unambiguously. This assignment was achieved by using a combination of one-and two-dimensional NMR techniques and computer modeling calculations.

The primary medicinal compounds of this plant are shown in the list below.

  • bigelovin
  • ergolide
  • germacrene A acid
  • inunolide
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating respiratory ailments such as cough, asthma, bronchitis, and phlegm, as well as managing digestive issues and inflammation. Its medicinal properties are frequently applied to alleviate symptoms of common colds and influenza. Practitioners often utilize the leaves or roots to address skin conditions and promote wound healing. Additionally, some traditional practices incorporate the plant to help regulate blood pressure and reduce fever. These diverse applications stem from the plant's natural bioactive compounds.

Evidence Level: ★☆☆☆☆

What are the herbal preparations of this plant?

This plant is Inula hupehensis, a species used in traditional medicine to create decoctions, powders, and tinctures primarily for treating respiratory ailments and inflammation.

The dried roots and aerial parts are often boiled in water to create a bitter medicinal tea that helps clear phlegm and soothe coughs. Some practitioners grind the dried material into a fine powder to be encapsulated or mixed with honey for easier consumption. Additionally, topical ointments can be prepared from the plant to reduce localized swelling and pain.

These diverse preparations allow the plant's active compounds to be delivered effectively for various therapeutic purposes.

Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause allergic skin reactions, gastrointestinal distress, and potential interference with blood clotting mechanisms. Some individuals may experience itching or rashes upon direct contact with the plant's tissues. Ingestion can lead to nausea, stomach cramps, or diarrhea in sensitive users. Furthermore, certain compounds within the plant might affect how the body regulates coagulation. Careful monitoring is necessary to avoid these adverse physiological responses.

The main side effects this plant can have are shown in the list below.

    Evidence Level: ★☆☆☆☆

    What herbs are paired with Inula hupehensis?

    This plant Inula hupehensis is most commonly paired with herbs such as Astragalus membranaceus, Glycyrrhiza uralensis, and Panax ginseng to enhance its warming and blood-circulating properties.

    These combinations are frequently utilized in traditional formulations to address deficiencies in vital energy and improve overall systemic circulation. When paired with Astragalus, the mixture focuses on strengthening the protective qi of the body. The addition of licorice root often serves to harmonize the different medicinal components and mitigate potential harshness.

    Practitioners select these specific pairings to balance the plant's inherent heat and direct it toward specific physiological needs.

    Evidence Level: ★☆☆☆☆