Indigofera suffruticosa

What's the taxonomical classification of Indigofera suffruticosa?

Indigofera suffruticosa belongs to the kingdom Plantae and is classified within the phylum Streptophyta. Following its taxonomic descent, it is situated in the class Equisetopsida and the subclass Magnoliidae. The plant is a member of the order Fabales and falls under the family Fabaceae. Within this family, it is categorized under the genus Indigofera, specifically identified by its species name, suffruticosa.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Fabales
Family Fabaceae
Genus Indigofera
Species suffruticosa
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Indigofera suffruticosa has a perennial shrubby habit characterized by erect, woody stems that typically reach a height of one meter and feature pinnate leaves with multiple small, oblong leaflets. The foliage is arranged alternately along the branches, presenting a bright green color and a fine, feathery texture. Small, pea-like flowers emerge in axillary racemes, displaying shades of pale yellow or cream. These blossoms eventually give rise to small, linear pods that contain several tiny seeds. The overall structure of the plant is compact and bushy, suitable for various tropical environments.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the tropical and subtropical regions of the Americas, extending from the Caribbean islands through Central America and into parts of South America. It is commonly found inhabiting disturbed areas, forest edges, and coastal regions where sunlight is abundant. Its presence is particularly noted in countries such as Brazil, Colombia, and various nations throughout the West Indies. Because it thrives in warm climates, it remains restricted to low-latitude zones that avoid frost. The species also appears in localized pockets across parts of Africa due to human-mediated dispersal.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant Indigofera suffruticosa thrives in tropical and subtropical climates with well-drained soil and consistent moisture levels.

Cultivation requires a warm growing season to ensure the nitrogen-fixing roots can effectively enrich the earth. Farmers typically plant the seeds during the onset of the rainy season to promote rapid vegetative growth. Regular weeding and monitoring for specific pests are necessary to maintain high concentrations of indigo dye within the leaves.

Once the foliage reaches maturity, it is harvested to undergo the complex fermentation processes required for pigment extraction.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant uses its leaves for various medicinal purposes including treating skin conditions and wounds. These leaves contain bioactive compounds that provide anti-inflammatory and antimicrobial properties to the user. When crushed or processed into a paste, the foliage can be applied topically to soothe irritations. Some traditional practices also involve using leaf extracts to address internal ailments or infections. This specific part of the plant remains the most significant component for therapeutic applications.

According to a study published by "Journal of ethnopharmacology", all parts of Indigofera suffruticosa are used for medicinal outcomes, while leaves are specifically used in teas, decoctions, juices, and baths to treat fever and inflammatory processes. Phytochemical analysis of the leaf aqueous extract revealed flavonoids and acid gallic in a quantity of 33.9 mg QE/g. Acute toxicity evaluation in mice resulted in a LD50 of 3807.88 mg/kg. In the carrageenan-induced paw edema test, doses of 20 and 100 mg/kg reduced edema by 83.93%. The extract inhibited the number of contortions in the writhing test by 72.60%, and a concentration of 100 mg/kg reduced fever significantly. Additionally, at a concentration of 0.5 mg/mL, the extract showed inhibition of protein denaturation.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaves
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, commonly known as indigo, has been used historically as a primary source for producing deep blue organic dye through a complex fermentation and oxidation process.

Ancient civilizations in South Asia and parts of Africa developed sophisticated methods to extract the pigment from its leaves to color textiles like cotton and silk. These traditional systems involved soaking the plant material in water to trigger fermentation before aerating the liquid to precipitate the dye. Beyond its role in the textile industry, various cultures utilized different parts of the shrub for medicinal purposes to treat skin ailments and inflammation.

This long history of cultivation established indigo as one of the most significant botanical commodities in global trade networks.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Indigofera suffruticosa?

This plant has analgesic, anti-inflammatory, anti-nociceptive, antibacterial, and antimicrobial pharmacological activities. Its ability to reduce pain and sensitivity to painful stimuli is demonstrated through its potent analgesic and anti-nociceptive properties. Additionally, the plant functions as an effective anti-inflammatory agent by suppressing various inflammatory responses in biological systems. The presence of bioactive compounds also allows it to act as a strong antimicrobial and antibacterial substance against diverse pathogens. These diverse medicinal properties make it a significant subject for pharmaceutical research and traditional healing applications.

According to a study published by "Journal of ethnopharmacology", Indigofera suffruticosa leaf aqueous extract contains flavonoids and acid gallic in a quantity of 33.9 mg QE/g. The acute toxicity evaluation of the extract resulted in a LD50 of 3807.88 mg/kg. For the carrageenan-induced paw edema test, IsAE at doses of 20 and 100 mg/kg reduced the edema by 83.93%. In the writhing test, IsAE inhibited the number of contortions by 72.60%. Furthermore, a concentration of 100 mg/kg reduced fever significantly, while a concentration of 0.5 mg/mL showed inhibition of protein denaturation.

The primary pharmacological activities of this plant are shown in the list below.

  • analgesic
  • anti-inflamatary
  • anti-nociceptive
  • antibacterial
  • antimicrobial
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compounds indican, indigotin, flavonoids, alkaloids, and tannins. The precursor indican is chemically converted into the pigment indigotin during the fermentation process. Beyond these dyes, the presence of various flavonoids provides significant antioxidant properties to the leaves. Alkaloids and tannins contribute to the plant's complex chemical profile and potential antimicrobial effects. These diverse bioactive substances make the species a subject of interest in pharmacological studies.

According to a study published by "Journal of ethnopharmacology", phytochemical analysis of Indigofera suffruticosa leaf aqueous extract revealed the presence of flavonoids and acid gallic in a quantity of 33.9 mg QE/g. Acute toxicity evaluation of this extract resulted in a LD50 of 3807.88 mg/kg in mice. In the carrageenan-induced paw edema test, doses of 20 and 100 mg/kg reduced edema by 83.93%. The extract inhibited the number of contortions in the writhing test by 72.60%. Furthermore, at a concentration of 0.5 mg/mL, it showed inhibition of protein denaturation, and a concentration of 100 mg/kg significantly reduced fever.

The primary medicinal compounds of this plant are shown in the list below.

  • Since the provided list only contains two items ("acid gallic" and "flavonoids"), it is impossible to extract five. However, based on the compounds present in your list:
  • acid gallic
  • flavonoids
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for the treatment of fever, inflammation, inflammatory processes, and various forms of pain including analgesy. Its bioactive compounds work to reduce swelling and soothe bodily discomfort. Practitioners often utilize its properties to manage acute inflammatory processes that affect different tissues. The plant also serves as a natural remedy to lower body temperature during a fever. Furthermore, it provides relief for persistent pain through its inherent analgesic qualities.

According to a study published by "Journal of ethnopharmacology", Indigofera suffruticosa is used for analgesy, fever, and inflammatory processes. The leaves are used in teas, decoctions, juices, and baths, with phytochemical analysis revealing 33.9 mg QE/g of flavonoids and acid gallic. In tests for carrageenan-induced paw edema, doses of 20 and 100 mg/kg reduced edema by 83.93%. The extract also inhibited contractions by 72.60% in the writhing test and showed protein denaturation inhibition at a concentration of 0.5 mg/mL. Additionally, a concentration of 100 mg/kg significantly reduced fever, while the acute toxicity evaluation resulted in an LD50 of 3807.88 mg/kg.

The main health conditions this plant is used for are shown in the list below.

  • inflammation
  • inflammatory processes
  • pain
  • fever
  • analgesy
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is used to create medicinal herbal preparations such as aqueous extracts, decoctions, and teas to treat various ailments. An aqueous extract is often prepared by soaking the plant material in water to draw out its soluble active compounds. Decoctions involve boiling the tougher parts of the plant, like stems or roots, in water for an extended period to ensure complete extraction. Teas are typically made by steeping the leaves in hot water for a shorter duration to create a milder infusion. These different methods allow practitioners to tailor the strength and concentration of the remedy to the specific needs of the patient.

According to a study published by "Journal of ethnopharmacology", all parts of Indigofera suffruticosa are used for medicinal outcomes, including leaves used in teas, decoctions, juices, and baths to treat fever and inflammatory processes. Phytochemical analysis of the leaf aqueous extract revealed flavonoids and acid gallic in a quantity of 33.9 mg QE/g. Acute toxicity evaluation in mice resulted in a LD50 of 3807.88 mg/kg. In the carrageenan-induced paw edema test, doses of 20 and 100 mg/kg reduced edema by 83.93%. The extract inhibited the number of contortions in the writhing test by 72.60%, and a concentration of 100 mg/kg significantly reduced fever. Additionally, at a concentration of 0.5 mg/mL, the extract showed inhibition of protein denaturation.

The main herbal preparations of this plant are shown in the list below.

  • aqueous extract
  • decoctions
  • teas
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause severe health issues including chromosome aberrations and hepatotoxicity when consumed or handled improperly. Research indicates that certain extracts from the plant possess mutagenic properties that lead to structural changes in genetic material. These chromosomal abnormalities pose a significant risk to cellular stability and long-term genetic integrity. Furthermore, the chemical compounds within the species can trigger hepatotoxicity, resulting in significant damage to liver cells. Such toxic effects necessitate extreme caution regarding any medicinal or industrial application of the plant.

According to a study published by "Memorias do Instituto Oswaldo Cruz", a hepatotoxic effect was observed in animals treated with the aqueous fruit extract of Indigofera suffruticosa. Regarding toxicogenetic effects, a group treated with 12.5% of the toxic dose of the aqueous fruit extract of Indigofera suffruticosa showed a statistically significant increase in the frequency of cells with chromosome aberrations. These results indicate that a careful evaluation must be done before the wide use of Indigofera suffruticosa in cattle food.

The main side effects this plant can have are shown in the list below.

  • chromosome aberrations
  • hepatotoxicity
Evidence Level: ★★★☆☆

What herbs are paired with Indigofera suffruticosa?

This plant Indigofera suffruticosa pairs effectively with holy basil, turmeric, and ginger to enhance its anti-inflammatory and wound-healing properties in traditional herbal formulations.

When used for topical applications, combining it with aloe vera or neem can provide a soothing effect on irritated skin. In decoctions intended for internal wellness, adding peppermint or licorice root helps to balance the earthy flavor profile of the indigo leaves. These combinations are often studied for their synergistic effects on boosting the immune system and managing oxidative stress.

Such pairings allow practitioners to tailor the plant's medicinal potency to specific therapeutic needs.

Evidence Level: ★☆☆☆☆