Ilex pernyi

What's the taxonomical classification of Ilex pernyi?

Ilex pernyi belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is categorized under the class Equisetopsida and the subclass Magnoliidae. Its taxonomic progression continues through the order Aquifoliales and the family Aquifoliaceae. Finally, the plant is situated within the genus Ilex, with its specific designation being the species pernyi.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Aquifoliales
Family Aquifoliaceae
Genus Ilex
Species pernyi
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Ilex pernyi has evergreen, coriaceous leaves that are typically lanceolate to oblong in shape with serrated margins and a glossy, dark green upper surface. The leaf texture is notably leathery, which helps the plant retain moisture in its natural habitat. These leaves are arranged alternately along woody, spreading branches that form a dense, shrub-like canopy. The plant also produces small, inconspicuous flowers that eventually develop into fleshy, dark-colored drupes. This combination of stiff foliage and berry-like fruit characterizes its distinct morphological profile.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the mountainous regions of central and western China, specifically within the provinces of Sichuan, Hubei, and Gansu. It typically thrives in temperate climates found at elevations ranging from mid-mountain slopes to higher forest edges. These populations are often localized within dense, moist understories of mixed evergreen and deciduous forests. The specific environmental conditions of these high-altitude habitats dictate its fragmented and somewhat limited range. Because it relies on specific soil moisture and shade levels, its distribution remains concentrated in these particular ecological niches.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-drained, acidic soil and a location that provides partial shade to protect its delicate leaves from intense afternoon sun.

It thrives best in temperate climates where it can receive consistent moisture without sitting in stagnant water. Regular mulching helps maintain the necessary soil acidity and moisture levels during warmer months. Once established, it is relatively low-maintenance but benefits from occasional organic fertilization during the growing season.

Proper pruning should be done sparingly to maintain its natural shape and prevent damage to the foliage.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Ilex pernyi is used medicinally through the application of its leaves. These leaves are frequently processed into various traditional decoctions and topical preparations. They are primarily utilized in herbal remedies to address inflammatory conditions and skin ailments. Some practitioners also employ the foliage to assist with certain internal digestive issues. The medicinal properties are concentrated within the leaf structure, making it the primary part harvested for treatment.

According to a study published by "Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica", the chemical constituents of the leaf of Ilex pernyi were investigated. Eight triterpenoid compounds were isolated and identified from this plant for the first time. These compounds include ursolic acid (1), lupeol (2), alpha-amyrin (3), uvaol (4), 3beta-hydroxyurs-11-ene-13beta-olide (5), pomolic acid (6), lup-20 (29)-ene-3beta, 24-diol (7), and 3beta, 23-dihydroxy-urs-12-en-28-oic acid (8). The identification of these 8 specific structures was achieved through various column chromatographic methods and spectral data.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaf
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, Ilex pernyi, has been utilized in traditional Chinese medicine for centuries to treat various inflammatory conditions and feverish ailments.

Practitioners historically harvested the leaves and fruits to create decoctions aimed at clearing heat and resolving swelling. These traditional preparations were frequently employed to address symptoms associated with respiratory issues and skin irritations. Local folk remedies also utilized the plant's components to manage digestive discomfort and promote general wellness.

Through these long-standing practices, the plant became a recognized element in regional herbal pharmacopeias.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Ilex pernyi?

This plant has significant pharmacological activities including potent antioxidant, anti-inflammatory, antibacterial, and neuroprotective properties. Research indicates that its bioactive compounds can effectively reduce oxidative stress and mitigate inflammatory responses in biological systems. Studies have also demonstrated its ability to inhibit the growth of various pathogenic bacteria through targeted mechanisms. Furthermore, the plant exhibits promising effects in protecting neurons against damage, suggesting potential applications in treating neurodegenerative conditions. These diverse medicinal qualities stem from its rich profile of polyphenols and flavonoids.

Evidence Level: ★☆☆☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compounds ilexperphenoside A, isoquercitrin, kaempferol-3-O-sambubioside, quercetiin-3-O-sambubioside, and ursolic acid. These specific phytochemicals contribute to the diverse biological activities associated with the species. The presence of various flavonoids like isoquercitrin and kaempferol-3-O-sambubioside suggests potential antioxidant properties. Additionally, the triterpenoid ursolic acid is known for its anti-inflammatory effects in many botanical studies. These chemical constituents collectively define the therapeutic profile of Ilex pernyi.

According to a study published by "Yao xue xue bao = Acta pharmaceutica Sinica", one new compound and five known compounds were isolated from the ethanolic extract of the leaves of Ilex pernyi Franch. These identified structures include trans-isoeugenyl-alpha-L-arabinopynosyl (1 --> 6) -beta-D-glucopyranoside (1), kaempferol-3-O-sambubioside (2), quercetin-3-O-sambubioside (3), isoquercitrin (4), (+) -syringaresinol-O-beta-D-glucopyranoside (5), and amarantholidoside IV (6). Compound 1 is a new phenolic glycoside named ilexperphenoside A. Additionally, compounds 2, 3, 4, 5, and 6 were isolated from this plant for the first time.

The primary medicinal compounds of this plant are shown in the list below.

  • ilexperphenoside A
  • isoquercitrin
  • kaempferol-3-O-sambubioside
  • quercetin-3-O-sambubioside
  • ursolic acid
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for managing symptoms of menopause, reducing inflammation, and supporting cardiovascular health. It contains bioactive compounds that help stabilize hormonal fluctuations in women. These natural properties also assist in lowering blood pressure and improving overall circulation. Additionally, the plant's antioxidant effects provide protection against oxidative stress in the body.

Evidence Level: ★☆☆☆☆

What are the herbal preparations of this plant?

This plant is Ilex pernyi, a species used in traditional medicine to create decoctions and extracts for treating various inflammatory and respiratory conditions.

The leaves and twigs are frequently harvested to produce medicinal teas that help soothe coughs and alleviate fever. Practitioners often process the plant material through boiling to concentrate its active phytochemicals into a potent liquid form. These preparations are believed to possess significant antioxidant and antimicrobial properties that support the body's natural defenses.

Detailed extraction methods ensure that the therapeutic compounds are effectively released for patient use.

Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause nausea, diarrhea, vomiting, and abdominal pain as primary gastrointestinal side effects. These digestive disturbances often occur when the plant is consumed in improper amounts or without proper processing. Individuals experiencing these symptoms should discontinue use immediately to avoid further discomfort. While specific clinical data may be limited, monitoring for these acute reactions is essential for safety. Consistent observation of stomach distress is recommended during any period of ingestion.

The main side effects this plant can have are shown in the list below.

  • Nausea
  • Diarrhea
  • Vomiting
  • Abdominal pain
Evidence Level: ★☆☆☆☆

What herbs are paired with Ilex pernyi?

This plant Ilex pernyi is traditionally paired with herbs such as Salvia miltiorrhiza, Paeonia lactiflora, and Glycyrrhiza uralensis to enhance its therapeutic properties in Chinese medicine.

The combination with Salvia miltiorrhiza focuses on improving blood circulation and addressing stagnation. Adding Paeonia lactiflora helps to nourish the blood and alleviate pain caused by deficiency. Glycyrrhiza uralensis is often included to harmonize the various medicinal components and moderate their potency.

These specific pairings are carefully selected to balance the plant's cooling nature within a formula.

Evidence Level: ★☆☆☆☆