Ilex cornuta

What's the taxonomical classification of Ilex cornuta?

Ilex cornuta belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is categorized under the class Equisetopsida and the subclass Magnoliidae. Moving down the taxonomic hierarchy, the plant is situated in the order Aquifoliales and the family Aquifoliaceae. Finally, it is identified by its specific genus, Ilex, and its unique species designation, cornuta.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Aquifoliales
Family Aquifoliaceae
Genus Ilex
Species cornuta
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Ilex cornuta has stiff, leathery, evergreen leaves that are dark green, elliptical in shape, and characterized by sharp, spine-tipped teeth along their margins. These leaves typically measure between one and three inches in length and possess a thick, waxy cuticle that aids in moisture retention. The plant produces small, inconspicuous white flowers that emerge in clusters during the spring season. Following pollination, it develops small, spherical drupes that transition from green to a deep black color upon maturity. The woody stems are densely branched, contributing to a compact and rounded growth habit.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the temperate and subtropical regions of East Asia, specifically spanning across China, Japan, Korea, and Taiwan. It thrives primarily in the moist, well-drained soils found within mountain forests and coastal shrublands. Within these habitats, it often grows in partial shade or under the canopy of larger deciduous trees. Its distribution is largely influenced by the humid climates characteristic of these East Asian territories. This specific range allows the species to adapt to varying elevations throughout its natural environment.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-drained, slightly acidic soil and a location that provides consistent moisture without allowing water to pool around the roots.

It thrives best in full sun to partial shade, depending on the specific variety and desired growth rate. Regular watering is essential during the establishment phase, though mature specimens can tolerate moderate drought periods. Mulching around the base helps maintain soil moisture and regulates temperature during seasonal shifts.

Periodic pruning in early spring or late summer can help maintain its shape and encourage dense foliage.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Ilex cornuta is utilized medicinally through the application of its bark, folium, fruits, roots, and stems. The leaves, or folium, are often prepared as infusions to address various inflammatory conditions. Extracts derived from the bark and stems provide bioactive compounds that support therapeutic treatments. Additionally, the fruits are processed for their specific nutritional and healing properties. Even the roots are harvested to create potent medicinal preparations used in traditional practices.

According to a study published by "Journal of ethnopharmacology", the dried leaves of Ilex cornuta, known as Kuding tea, have been utilized as an herbal drink for over 2000 years. During the Tang Dynasty, the bark was steeped in wine to create a medicinal liquor intended to tonify the liver and kidneys. Both the leaves and branches have been traditionally used to treat endocrine issues, metabolic problems, and hemoptysis caused by pulmonary tuberculosis. To date, 205 compounds have been identified in Ilex cornuta, including 82 triterpenoids, 15 flavonoids, and 87 volatile compounds. These identified components contribute to various pharmacological activities, such as regulating systemic metabolism and promoting bone remodeling.

The parts of this plant that are ued medicinally are shown in the list below.

  • bark
  • folium
  • fruits
  • roots
  • stems
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, known as Shui Zhu Ye in Traditional Chinese Medicine, is primarily utilized for its ability to clear heat, resolve toxicity, and promote the discharge of pus. Historically, the dried leaves have been prepared as decoctions to treat various inflammatory conditions, including skin abscesses and sore throats. Practitioners have long valued the plant for its cooling properties, which help to reduce fever and alleviate swelling. In many regional folk practices, the leaves are also applied topically to soothe localized infections. This long-standing botanical history underscores its specialized role in managing heat-related ailments within ancient medicinal frameworks.

According to a study published by "Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica", Ilex cornuta is one of the varieties most widely used in Traditional Chinese medicine to clear heat and remove toxin. This plant is utilized in clinical practice for its effect of removing fire-heat and toxin. It contains chemical components including triterpenoids, their glycosides, alkaloids, flavonoids, and phenylpropanoids. Specifically, these plants contain pentacyclic triterpenoids which can be divided into types such as oleanane, ursane, and lupinane. Within these categories, ursane-type components are the most abundant, and 136 species have been found so far.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional Chinese Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Ilex cornuta?

This plant has anti-inflammatory, clearing heat and removing toxin, inhibiting bacteria, phytopathogen-inhibiting, and protecting cardiomyocytes pharmacological activities. Its diverse medicinal properties allow it to combat various infections by suppressing the growth of harmful microorganisms. The extract also plays a crucial role in regulating inflammatory responses within the body. Furthermore, specific compounds found in the plant assist in detoxifying biological systems and soothing heat-related ailments. Finally, it offers significant cardiovascular benefits by providing protection to cardiomyocyte cells against injury.

According to a study published by "Journal of ethnopharmacology", Ilex cornuta has been used for over 2000 years to treat issues such as hemoptysis from pulmonary tuberculosis, endocrine issues, and metabolic problems. A total of 205 compounds have been identified in the plant, including 82 triterpenoids, 15 flavonoids, and 87 volatile compounds. The pharmacological activities of Ilex cornuta include promoting bone remodeling, regulating systemic metabolism, exerting anti-inflammatory effects, inhibiting bacteria, and protecting cardiomyocytes. It shows therapeutic potential in metabolic disorders including obesity, hyperuricemia, and non-alcoholic fatty liver disease. These activities involve influencing metabolic pathways through MAPK, AMPK, and PPARγ/ADRP signaling pathways.

The primary pharmacological activities of this plant are shown in the list below.

  • anti-inflammatory
  • clearing heat and removing toxin
  • inhibiting bacteria
  • phytopathogen-inhibiting
  • protecting cardiomyocytes
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains a diverse array of bioactive medicinal compounds including flavonoids, glycosides, pentacyclic triterpenoids, phenylpropanoids, and triterpenoids. These specific chemical constituents contribute to the plant's significant pharmacological potential and therapeutic properties. The presence of flavonoids and phenylpropanoids often provides antioxidant and anti-inflammatory benefits to the organism. Additionally, the complex structures of the glycosides and various triterpenoids play critical roles in its biological activities. Together, these phytochemicals form a potent medicinal profile within the leaves and stems of Ilex cornuta.

According to a study published by "Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica", Ilex cornuta contains chemical components including triterpenoids and their glycosides, alkaloids, flavonoids, phenylpropanoids, and other substances. These plants especially contain pentacyclic triterpenoids which can be divided into the oleanane type, the ursane type, and the lupinane type. Among these, ursane-type components are the most abundant, and 136 species have been found so far. These components have been proved to have pharmacological effects such as anti-inflammatory, anti-tumor, hypolipidemic, anti-thrombosis, cardiomyocyte-protective, antibacterial, and hepatoprotective effects.

The primary medicinal compounds of this plant are shown in the list below.

  • flavonoids
  • glycosides
  • pentacyclic triterpenoids
  • phenylpropanoids
  • triterpenoids
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating kidney weakness, liver weakness, non-alcoholic fatty liver disease, metabolic problems, and endocrine issues. It functions by supporting the natural detoxification processes within the hepatic system to combat fatty accumulation. The botanical properties also assist in regulating hormonal balances to address various endocrine issues. Furthermore, its medicinal applications extend to stabilizing metabolic functions and strengthening renal capacity. These combined effects make it a versatile tool for managing complex internal systemic imbalances.

According to a study published by "Journal of ethnopharmacology", Ilex cornuta has been used for over 2000 years as an herbal drink. Traditionally, its bark was used in medicinal liquor to tonify the liver and kidneys and relieve weakness and fatigue in the lower back and limbs. The leaves and branches have been utilized to treat hemoptysis caused by pulmonary tuberculosis, endocrine issues, and metabolic problems. It shows therapeutic potential in metabolic disorders such as obesity, hyperuricemia, and non-alcoholic fatty liver disease. The plant contains 205 identified compounds, including 82 triterpenoids, 15 flavonoids, and 87 volatile compounds.

The main health conditions this plant is used for are shown in the list below.

  • kidney weakness
  • liver weakness
  • non-alcoholic fatty liver disease
  • metabolic problems
  • endocrine issues
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is Ilex cornuta, a species used in traditional medicine to create preparations such as Kuding tea and medicinal liquor. Kuding tea is commonly brewed from the leaves to support various health benefits in folk practices. The medicinal liquor is typically made by steeping the plant parts in alcohol to extract its active compounds. These different forms allow for various methods of consumption depending on the desired therapeutic effect. Practitioners often utilize these specific preparations to address specific ailments within traditional healing systems.

According to a study published by "Journal of ethnopharmacology", the dried leaves of Ilex cornuta, known as Kuding tea, have been used as an herbal drink for over 2000 years. During the Tang Dynasty, its bark was steeped in wine to create a medicinal liquor used to tonify the liver and kidneys. Modern herbal medicines such as Hua Mo Yan Capsule, Feng Tong Pill, and Qing Shen Yin Granule include Ilex cornuta as a main ingredient. To date, 205 compounds have been identified in the plant, which include 82 triterpenoids, 15 flavonoids, and 87 volatile compounds. These bioactive constituents contribute to various pharmacological activities, including regulating systemic metabolism and protecting cardiomyocytes.

The main herbal preparations of this plant are shown in the list below.

  • Kuding tea
  • medicinal liquor
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause adverse health effects such as gastrointestinal distress, skin irritation, and potential allergic reactions when handled or consumed improperly. The presence of specific saponins and tannins within its tissues may lead to stomach upset or nausea if ingested. Direct contact with the leaves or stems often results in localized dermatitis or itching for sensitive individuals. Furthermore, some users may experience hypersensitivity symptoms ranging from mild rashes to more severe systemic responses. Monitoring these reactions is essential for anyone interacting with the species.

The main side effects this plant can have are shown in the list below.

    Evidence Level: ★☆☆☆☆

    What herbs are paired with Ilex cornuta?

    This plant, Ilex cornuta, pairs most effectively with aromatic herbs such as rosemary, thyme, and lavender to balance its structural rigidity with sensory complexity.

    The resinous notes of rosemary complement the evergreen foliage, creating a cohesive scent profile in garden compositions. Thyme provides a delicate textural contrast that softens the sharp, spiny leaves of the holly. Lavender adds a calming purple hue and floral fragrance that prevents the shrub from appearing too austere.

    Integrating these specific herbs ensures a multi-layered aesthetic and olfactory experience in any landscape design.

    Evidence Level: ★☆☆☆☆