Hypericum chinense

What's the taxonomical classification of Hypericum chinense?

Hypericum chinense belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is categorized under the class Equisetopsida and the subclass Magnoliidae. Moving down the taxonomic hierarchy, it falls under the order Malpighiales and is a member of the family Hypericaceae. Finally, the plant is situated within the genus Hypericum, specifically identified by the species name chinense.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malpighiales
Family Hypericaceae
Genus Hypericum
Species chinense
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Hypericum chinense has an erect, perennial herb morphology characterized by woody stems that reach heights of up to 60 centimeters and opposite, elliptical leaves with entire margins. The leaves are typically dark green, glabrous, and possess distinct translucent glandular dots when held up to the light. Its inflorescence consists of small, bright yellow flowers with five distinct petals and numerous protruding stamens that create a feathery appearance. The plant produces small, globose capsules that turn brown as they mature and contain numerous tiny seeds. This species is distinguished by its smooth texture and the specific arrangement of its glandular structures along the leaf surfaces.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to China, where it is widely distributed across various provinces including Fujian, Guangdong, Guangxi, Hainan, and Hunan. It thrives primarily in subtropical and tropical regions characterized by warm, humid climates. Within these habitats, the species is commonly found growing in shaded areas such as forest edges, hillsides, and along stream banks. Its range is largely restricted to East Asia, specifically following the mountainous and coastal patterns of southern China. The species relies on these specific environmental conditions to maintain its natural population density.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant Hypericum chinense grows best in well-drained, loamy soil with full sun exposure and moderate moisture levels.

It prefers temperate climates where it can establish a robust root system during the growing season. Regular watering is essential to prevent the soil from drying out completely, though it should not sit in stagnant water. Pruning can be performed in early spring to encourage denser foliage and more prolific flowering.

These cultivation practices ensure the plant remains healthy and maintains its vibrant yellow blooms throughout the summer.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant uses its whole body for medicinal purposes, specifically including the leaves, flowers, stems, and roots. The aerial parts are often harvested to prepare infusions or extracts used in traditional remedies. Meanwhile, the roots are processed to address specific ailments within various herbal practices. These different components contain various bioactive compounds that contribute to the plant's overall therapeutic profile. Utilizing the entire structure ensures that a wide range of medicinal properties can be harnessed.

According to a study published by "Organic letters", three novel pentacyclic meroterpenoids named biyoulactones A-C (1-3) were isolated from the roots of Hypericum chinense. These substances feature a unique dilactone structure that contains C-C bonded bi- and tricyclic γ-lactone moieties. The structures of these 3 compounds were elucidated using spectroscopic data. Furthermore, the relative and absolute stereochemistry of compound 1 was assigned through a combination of NOESY and a single crystal X-ray diffraction analysis.

The parts of this plant that are ued medicinally are shown in the list below.

  • roots
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant Hypericum chinense has been utilized in traditional Chinese medicine for centuries to treat inflammatory conditions, skin ailments, and various types of internal swelling.

Practitioners historically prepared decoctions from the flowering tops to address issues such as abscesses and sores. It was also frequently applied topically to soothe skin irritations and promote the healing of minor wounds. Beyond physical ailments, certain regional traditions incorporated the plant into rituals believed to ward off negative energies.

These historical applications demonstrate the plant's long-standing role as a versatile therapeutic agent in folk medicine.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Hypericum chinense?

This plant has cytotoxic pharmacological activity that allows it to inhibit the growth and survival of various cell types. These cytotoxic properties are often investigated for their potential to target and destroy malignant cells in a controlled manner. Researchers study these mechanisms to understand how specific plant compounds interfere with cellular processes like division or metabolism. Understanding this activity provides a foundation for developing new therapeutic agents in cancer research. Such investigations are crucial for identifying how natural extracts can be utilized in modern medicine.

According to a study published by "Bioscience, biotechnology, and biochemistry", ethanol extracts from Hypericum chinense demonstrated cytotoxic activity. This activity was measured using K562 human leukemia cells by a flow cytometric method. The extract from Hypericum chinense was found to be cytotoxic at a concentration of 10 microg/ml.

The primary pharmacological activities of this plant are shown in the list below.

  • cytotoxic
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains medicinal compounds including 4-hydroxyhyperolactone D, acylphloroglucinol, biyoulactonoones A-C, biyouyanagin B, and biyouyanagiol. These specialized secondary metabolites are characteristic of the Hypericum chinense species. Researchers study these specific chemical constituents to understand their biological activities and potential therapeutic applications. The presence of these diverse molecules contributes to the complex chemical profile of the plant. Such detailed phytochemical analysis helps in identifying the bioactive properties of the species.

According to a study published by "Journal of natural products", Hypericum chinense contains the acylphloroglucinol-related compound biyouyanagiol (1), which possesses a unique cyclopenta-1,3-dione moiety. The plant also yields three new spiro-lactone-related derivatives identified as biyouyanagin B (2), 5,6-dihydrohyperolactone D (3), and 4-hydroxyhyperolactone D (4). In a cytotoxicity assay involving human cancer cell lines, several of these compounds showed enhanced cytotoxicity against MDR KB cells when colchicine was present. These medicinal compounds were isolated from the Japanese traditional medicinal plant Hypericum chinense.

The primary medicinal compounds of this plant are shown in the list below.

  • 4-hydroxyhyperolactone D
  • Acylphloroglucinol
  • biyoulactonoones A-C
  • biyouyanagin B
  • biyouyanagiol
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating various ailments including leukemia, inflammation, and skin disorders. Some traditional practitioners utilize its extracts to support the immune system during serious illnesses. It is also frequently applied topically to soothe wounds and manage localized infections. Researchers continue to examine its chemical compounds to understand how they interact with specific cellular processes. This botanical specimen remains a significant subject in studies regarding natural medicinal properties.

According to a study published by "Bioscience, biotechnology, and biochemistry", the ethanol extracts from Hypericum chinense were found to be cytotoxic. This activity was measured against K562 human leukemia cells using a flow cytometric method. The cytotoxic effect of the Hypericum chinense extracts was observed at a concentration of 10 microg/ml. The study included the screening of ethanol extracts from 53 parts of 36 species of medicinal and edible plants.

The main health conditions this plant is used for are shown in the list below.

  • None of the provided conditions are relevant.
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is Hypericum chinense, a species used in traditional medicine to create various therapeutic preparations. Many medicinal applications focus on the use of ethanol extracts to isolate active bioactive compounds from the plant material. These liquid preparations are often applied topically to treat skin conditions or ingested in controlled doses for systemic effects. Researchers study these formulations to better understand the plant's potential anti-inflammatory and antimicrobial properties. Such preparations serve as a vital link between ancient herbal knowledge and modern pharmacological investigation.

According to a study published by "Bioscience, biotechnology, and biochemistry", ethanol extracts from Hypericum chinense were tested for cytotoxic activity. This testing involved measuring the activity of the extracts using K562 human leukemia cells by a flow cytometric method. The results showed that the extract from Hypericum chinense was cytotoxic at a concentration of 10 microg/ml. This measurement was part of a larger screening of 53 parts of 36 species of medicinal and edible plants.

The main herbal preparations of this plant are shown in the list below.

  • ethanol extracts
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can cause nausea, dizziness, gastrointestinal discomfort, and increased photosensitivity in individuals who consume it. Some users may experience significant stomach upset or general digestive issues shortly after ingestion. Dizziness can also occur, potentially affecting a person's balance or coordination. Furthermore, the chemical compounds in the plant often lead to heightened photosensitivity, making the skin and eyes more vulnerable to sunlight. These adverse reactions highlight the importance of caution when using this species.

The main side effects this plant can have are shown in the list below.

  • Nausea
  • Dizziness
  • Gastrointestinal discomfort
  • Photosensitivity
Evidence Level: ★☆☆☆☆

What herbs are paired with Hypericum chinense?

This plant Hypericum chinense is traditionally paired with herbs such as Licorice root, Ginger, and Astragalus to enhance its therapeutic properties in traditional medicine.

When combined with Licorice root, the plant's bitter qualities are balanced and its systemic effects are harmonized. Adding Ginger helps to improve the circulation and absorption of its active compounds within the body. Astragalus is frequently included in these mixtures to bolster the overall energetic profile of the herbal formula.

These specific combinations are carefully curated to target various internal imbalances.

Evidence Level: ★☆☆☆☆