Hylotelephium sieboldii
Hylotelephium sieboldii · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Hylotelephium sieboldii is a resilient plant species known for its unique biochemical profile and medicinal potential. Recent investigations have focused on the bioactive compounds found within its leaf tissue. Specifically, researchers have identified a significant presence of flavonoids throughout the plant's foliage. These chemical constituents have demonstrated notable cytotoxic activities during various laboratory assessments. Most importantly, these properties are being studied for their ability to combat the parasite Trypanosoma brucei.
- Synonyms
- Sedum Sieboldii
- Common names
- Not available
- Family
- Crassulaceae
- Distribution
- Not available
- Plant Parts
- Leaf
Classification
Common Names
Hylotelephium sieboldii is a versatile plant known by many different names depending on the region and language. In some areas, it is commonly referred to as Japans vetkruid or Orpin de Siebold. It also carries the title of Rozchodnik Siebolda, reflecting its botanical heritage. Gardeners may also recognize it as Siebold-Fetthenne when discussing its succulent properties. Finally, it is known in certain circles as Sieboldi kukehari, showcasing the wide variety of ways this species is identified.
Sources: Catalogue of Life (COL)
Synonyms
Hylotelephium sieboldii is a resilient perennial that brings texture and color to many garden landscapes. This plant is also widely recognized by its botanical synonym, Sedum sieboldii. While taxonomic classifications may shift over time, both names refer to the same charming species. Understanding these overlapping identities helps gardeners accurately identify the plant in various nursery catalogs. Whether you call it by its modern name or its traditional synonym, it remains a staple for stone gardens.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Hylotelephium sieboldii is a distinctive member of the kingdom Plantae. Within this vast biological realm, it is classified under the class Equisetopsida. Its evolutionary lineage continues through the order Saxifragales, showcasing its botanical connections. As a representative of the genus Hylotelephium, it displays unique structural characteristics. Finally, this plant belongs to the Crassulaceae family, grouping it with other diverse succulents.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Saxifragales |
| Family | Crassulaceae |
| Genus | Hylotelephium |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Hylotelephium sieboldii exhibits a broad geographical range that spans across multiple continents. In Asia, the species is widely distributed throughout temperate regions, specifically within China and Japan. Its presence extends into Europe, where it can be found across the Baltic States and throughout Eastern Europe. The plant is also well-established in Middle Europe, with notable populations in countries such as Germany. Furthermore, its reach continues into Southeastern Europe, including regions like Bulgaria.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Hylotelephium sieboldii is characterized by its distinct herb growth form, making it a versatile addition to many garden landscapes.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Hylotelephium sieboldii, also referred to as Sedum sieboldii, has demonstrated significant biological potential during recent pharmacological evaluations. Research indicates that the leaf extracts of this plant possess notable cytotoxic activity against several cancer cell lines, including HCT-116, HEPG-2, and MCF-7. In addition to its cytotoxic properties, the species exhibits antitrypanosomal activity against Trypanosoma brucei and shows inhibition against Topoisomerase-1. These potent biological effects are supported by a high concentration of phenolics and flavonoids within the extract. Chemical profiling via UHPLC/QTOF-MS/MS has successfully identified numerous secondary metabolites, such as coumarins and anthocyanidins, which may contribute to these therapeutic characteristics.
Compounds
Hylotelephium sieboldii, also referred to in studies as Sedum sieboldii, is a member of the Crassulaceae family that possesses significant medicinal potential. Chemical profiling of its leaf extracts reveals a rich composition of polar secondary metabolites, most notably a high concentration of flavonoids. These flavonoids, along with various phenolic acids, are thought to contribute to the plant's impressive biological activities. Research indicates that the extract exhibits potent antitrypanosomal effects against Trypanosoma brucei and demonstrates notable cytotoxicity against several cancer cell lines. Furthermore, the presence of these compounds supports the plant's ability to act as an inhibitor against Topoisomerase-1.
Conditions
Hylotelephium sieboldii, also known as Sedum sieboldii, demonstrates significant biological activity against several target organisms and enzymes. The plant extract exhibits potent antitrypanosomal activity against Trypanosoma brucei with an IC50 value of 8.5 µg/mL. It also functions as an inhibitor of Topoisomerase-1, showing an IC50 value of 1.31 µg/mL. Furthermore, the extract displays effective cytotoxic properties against the HCT-116 cell line. This cytotoxic effect extends to the HEPG-2 and MCF-7 cancer cell lines as well.
Preparations
Parts used
Hylotelephium sieboldii, also referred to as Sedum sieboldii, contains leaves that serve as a potent source of bioactive compounds. Research indicates that extracts derived from these leaves demonstrate significant antitrypanosomal activity against Trypanosoma brucei. Furthermore, the plant's foliage exhibits notable cytotoxic effects against various cancer cell lines, including HCT-116, HEPG-2, and MCF-7. These biological properties are supported by the leaf extract's ability to inhibit Topoisomerase-1 effectively. Chemical profiling reveals that these therapeutic activities are likely driven by a rich diversity of secondary metabolites, such as flavonoids and phenolic acids, found within the leaves.