Hydnocarpus annamensis

What's the taxonomical classification of Hydnocarpus annamensis?

Hydnocarpus annamensis belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is situated in the class Equisetopsida and the subclass Magnoliidae. The taxonomic hierarchy continues through the order Malpighiales and the family Achariaceae, which serves as the broader group for this specific organism. Finally, it is categorized under the genus Hydnocarpus, with the specific epithet annamensis identifying the individual species.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Malpighiales
Family Achariaceae
Genus Hydnocarpus
Species annamensis
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Hydnocarpus annamensis has a medium to large tree habit characterized by an elliptical to obovate leaf shape, an entire leaf margin, and a coriaceous texture. The foliage typically displays a glossy green upper surface with a paler underside. Its reproductive structures consist of small, inconspicuous flowers that eventually develop into woody, globose fruits. These fruits contain oily seeds which are a distinguishing feature of the genus. The bark is generally smooth or slightly fissured depending on the age of the specimen.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the tropical rainforest regions of Northeast India, specifically within the state of Assam. Its natural range is restricted to the moist deciduous and evergreen forest ecosystems of the Indo-Burma biodiversity hotspot. Within these habitats, it typically grows in the understory of dense, humid woodlands. The species is closely associated with the specific soil compositions and high rainfall patterns characteristic of this subtropical zone. Consequently, its distribution is highly localized to these specific ecological niches in South Asia.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant Hydnocarpus annaemensis requires a tropical rainforest environment with high humidity, consistent rainfall, and well-draining acidic soil to thrive.

Cultivation typically involves planting seeds in shaded areas to protect young saplings from intense direct sunlight. Growers must ensure the soil remains moist but never waterlogged to prevent root rot. Because this species is native to specific tropical ecosystems, maintaining a stable warm temperature is essential for its development.

Regular monitoring of soil nutrient levels helps support the healthy growth of its unique canopy.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Hydnocarpus annaemensis provides medicinal value primarily through its bark and seeds. The bark contains various bioactive compounds that are harvested for their therapeutic properties in traditional practices. Additionally, the seeds of the plant are a significant source of specialized oils used in different healing applications. These components are often processed to extract substances intended to treat various ailments. The diverse chemical makeup within these specific parts makes the species a subject of ethnobotanical interest.

According to a study published by "Planta medica", the bark of Hydnocarpus annamensis was used to isolate two new phenolic glycosides, 1 and 2, alongside eighteen known compounds. Among these isolates, compounds 1, 5, 15 and 17 exhibited COX-2 inhibitory activities with an inhibitory rate of 60.3 - 63.4 % at 10 microM. Additionally, compounds 7, 12, 13 and 20 demonstrated anti-oxidation capacities in the DPPH free-radical assay. These specific compounds showed a scavenging effect of 60.9 - 69.4 % at 50 microM and 18.5 - 34.6 % at 10 microM.

The parts of this plant that are ued medicinally are shown in the list below.

  • bark
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, Hydnocarpus annamensis, has been utilized in traditional medicine primarily for treating skin ailments and parasitic infections through its oil-rich seeds.

Indigenous communities in South and Southeast Asia historically extracted oil from the seeds to serve as a topical remedy for scabies and various fungal conditions. The oil was also applied to manage various dermatological issues by leveraging its natural antimicrobial properties. Beyond skin treatments, local practitioners sometimes incorporated components of the plant into broader holistic healing practices for topical antiseptic uses.

These historical applications highlight the plant's significance in ethnic pharmacopoeia before the advent of modern synthetic dermatological treatments.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Hydnocarpus annamensis?

This plant has significant pharmacological activities including anti-inflammatory, anti-oxidation, and antimicrobial properties derived from its unique chemical constituents. The presence of bioactive compounds allows it to effectively reduce swelling and inhibit the production of inflammatory mediators in biological systems. Furthermore, its potent anti-oxidation capacity helps neutralize free radicals and prevent cellular damage caused by oxidative stress. Research also suggests that extracts from the plant may possess various medicinal benefits useful in treating diverse pathological conditions. These combined effects highlight the therapeutic potential of Hydnocarpus annaensis in modern pharmacology.

According to a study published by "Planta medica", two new phenolic glycosides 1 and 2 were isolated from the barks of Hydnocarpus annamensis along with eighteen known compounds. Among these isolates, compounds 1, 5, 15 and 17 exhibited COX-2 inhibitory activities with an inhibitory rate of 60.3 - 63.4 % at 10 microM. Additionally, compounds 7, 12, 13 and 20 showed anti-oxidation capacities in the DPPH free-radical assay. These specific compounds demonstrated a scavenging effect of 60.9 - 69.4 % at 50 microM and 18.5 - 34.6 % at 10 microM.

The primary pharmacological activities of this plant are shown in the list below.

  • anti-inflammatory
  • anti-oxidation
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains medicinal compounds including phenolic glycosides 1, phenolic glycosides 2, compounds 1, compounds 12, and compounds 13. These specific chemical constituents are studied for their diverse biological activities and potential therapeutic applications. Researchers analyze these substances to understand how they interact with human cellular pathways. The presence of such varied organic structures suggests a complex chemical profile within the species. Detailed pharmacological testing is often required to determine the exact medicinal efficacy of each individual element.

According to a study published by "Planta medica", two new phenolic glycosides 1 and 2 were isolated from the barks of Hydnocarpus annamensis along with eighteen known compounds. Among these isolates, compounds 1, 5, 15 and 17 exhibited COX-2 inhibitory activities with an inhibitory rate of 60.3 - 63.4 % at 10 microM. Additionally, compounds 7, 12, 13 and 20 showed anti-oxidation capacities in the DPPH free-radical assay. These specific compounds demonstrated a scavenging effect of 60.9 - 69.4 % at 50 microM and 18.5 - 34.6 % at 10 microM.

The primary medicinal compounds of this plant are shown in the list below.

  • phenolic glycosides 1
  • phenolic glycosides 2
  • compounds 1
  • compounds 12
  • compounds 13
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for managing inflammation, oxidative stress, and various skin disorders through its potent bioactive compounds. Its medicinal properties are primarily attributed to the presence of specific fatty acids and antioxidants that combat cellular damage. These chemical constituents work to neutralize free radicals, thereby reducing the harmful effects of oxidation within the body. Additionally, the plant's ability to soothe swelling makes it an effective traditional remedy for inflammatory conditions. By addressing these underlying biological processes, it serves as a versatile tool in herbal medicine.

According to a study published by "Planta medica", Hydnocarpus annamensis is used for its anti-inflammatory and anti-oxidation activities. Within the bark of the plant, compounds 1, 5, 15 and 17 exhibited COX-2 inhibitory activities with an inhibitory rate of 60.3 - 63.4 % at 10 microM. Additionally, compounds 7, 12, 13 and 20 showed anti-oxidation capacities in the DPPH free-radical assay. These compounds demonstrated a scavenging effect of 60.9 - 69.4 % at 50 microM and 18.5 - 34.6 % at 10 microM. The study also identified eighteen known compounds alongside two new phenolic glycosides 1 and 2.

The main health conditions this plant is used for are shown in the list below.

  • inflammation
  • oxidation
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is used to create medicinal herbal preparations such as oils, extracts, and decoctions that primarily target skin infections and parasitic conditions.

The seeds are often processed into a therapeutic oil known for its potent antifungal and antiparasitic properties. Practitioners frequently apply these topical preparations to treat various fungal ailments and dermatological issues. Some traditional formulations may also involve boiling parts of the plant to create liquid extracts for systemic use.

These preparations rely heavily on the unique chemical compounds found within the plant's fatty seeds.

Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause skin irritation, gastrointestinal distress, and potential allergic reactions when consumed or applied topically. The bioactive compounds within the plant may trigger localized dermatitis or itching upon contact with sensitive skin. If ingested, individuals might experience nausea, stomach cramps, or general digestive upset. Some people may also develop systemic hypersensitivity or rashes as an immune response to its chemical constituents. Careful monitoring is necessary to avoid these adverse physiological reactions.

The main side effects this plant can have are shown in the list below.

    Evidence Level: ★☆☆☆☆

    What herbs are paired with Hydnocarpus annamensis?

    This plant Hydnocarpus annamensis is traditionally paired with herbs such as Zingiber officinale, Curcuma longa, and various species of Ocimum to enhance its medicinal efficacy.

    These combinations are often utilized in Ayurvedic formulations to balance the plant's potent bioactive compounds. Adding ginger and turmeric helps to mitigate potential digestive discomfort while simultaneously increasing the bioavailability of its lipid-soluble components. The inclusion of holy basil can further stabilize the mixture and provide additional antioxidant support during therapeutic applications.

    These synergistic pairings are specifically designed to target inflammatory conditions and skin ailments more effectively.

    Evidence Level: ★☆☆☆☆