hop
Humulus lupulus · Accepted scientific name
Scientific literature: Very Extensive (1328 studies) · ★★★★★
Hop, scientifically known as Humulus lupulus, is a climbing herbaceous perennial essential to brewing. Beyond flavoring beer, it possesses significant medicinal properties. Rich in essential oils and bitter acids, it acts as a natural sedative, aids sleep, reduces anxiety, and offers antioxidant benefits, making it a versatile botanical remedy.
Names
Common Names
- hop
- hops
- bine
- common hop
Regional and Traditional Names
Spanish:
- Betiguera
- H. lupulus
- Retigueras
- Canamiza
- Lupulo bravo
- Lúpulo
- Hombrecillos
- Esparragos de sortijilla
- Espárrago de soguilla
- Espárrago de río
- Lupiera
- Pina fofa
- Zaramancon
- Esparrago de rio
- Espárrago de ortiga
- Zaramangón
- Zaramangon
- Humulus lupulus var lupulus
- Espárragos de sortijilla
- Espárragos de ortiga
- Hombrecillo
- Cuerpo de hombre
- Esparrago de ortiga
- Pimienta blanquizca
- Flor de hombre
- Lupulus scandens
- Lupulo
- Lúpulo bravo
- Esparrago de río
- Espárrago de rio
- Ombrecillo
- Zaramancón
- Esparragos de culebra
- Esparrago de soguilla
- Esparragos de zarza
- Humulus lupulus var. lupulus
- Cañamiza
- H lupulus
- Lupina
- Lupo
- Esparragos de ortiga
- Piña fofa
- lúpulo
German:
- Echter Hopfen
- Gewöhnlicher Hopfen
- Humulus lupus
- Hopfen
- Hopfen
- Gewöhnlicher Hopfen
French:
- houblon
- Houblons
- Houblon grimpant
- Houblon
- houblon
- houblon commun
Scientific Names
Accepted name
Humulus lupulusSynonyms
- Lupulus humulus
- Humulus lupulus var. silvestris
- Waldensia lupulina
- Lupulus communis
- Humulus vulgaris
- Humulus lupulus var. acrocarpus
- Humulus lupulus var. effusus
- Humulus lupulus var. spaltensis
Taxonomical Classification
This plant, known scientifically as Humulus lupulus, belongs to the kingdom Plantae and the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is categorized under the order Rosales and the family Cannabaceae. Ultimately, its taxonomic identity is defined by the genus Humulus.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Rosales | WCVP |
| Family | Cannabaceae | WCVP |
| Genus | Humulus | WCVP |
Distribution
This plant, known as Humulus lupulus, is widely distributed across several regions in Northern Europe. In the southern reaches of this area, it can be found growing in Denmark. Moving further north, the species is also established in the landscapes of Norway and Finland. The plant's range extends westward to include the islands of Great Britain and Ireland. Together, these locations highlight the specific northern territories where the species thrives.
| Region | Area | Source |
|---|---|---|
| Northern Europe | Denmark | WCVP |
| Northern Europe | Finland | WCVP |
| Northern Europe | Great Britain | WCVP |
| Northern Europe | Ireland | WCVP |
| Northern Europe | Norway | WCVP |
| Northern Europe | Sweden | WCVP |
| Middle Europe | Austria | WCVP |
| Middle Europe | Belgium | WCVP |
| Middle Europe | Czechia-Slovakia | WCVP |
| Middle Europe | Germany | WCVP |
Plant Parts
This plant, Humulus lupulus, is a climbing perennial known for its complex structural components used in various medicinal and traditional applications. The botanical structure features distinct leaves that are deeply lobed, often serving as the primary site for gathering leaf extracts for their chemical properties. During its flowering stage, the plant produces a specialized inflorescence which typically develops into dense, resinous hop cones. These cone-like structures are found on the female plants and are the most commercially and medicinally significant parts of the species, often growing in clusters that can be described as part of the plant's reproductive racemes.| Plant Part | Sources | Consensus |
|---|---|---|
| flower | Planta medica (and other 2 sources) | ★☆☆☆☆ |
| leaf | Molecules (Basel, Switzerland) (and other 2 sources) | ★☆☆☆☆ |
Chemicals
Humulus lupulus has 310 reported phytochemicals identified across 4 scientific publications and several other databases. The most consistently reported chemicals include Xanthohumol, 8-Prenylnaringenin, Isoxanthohumol, polyphenols, 6-Prenylnaringenin.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Xanthohumol | 19 supporting sources | ★★★★★ |
| 8-Prenylnaringenin | 12 supporting sources | ★★★★★ |
| Isoxanthohumol | 8 supporting sources | ★★★★☆ |
| polyphenols | 5 supporting sources | ★★★☆☆ |
| 6-Prenylnaringenin | 4 supporting sources | ★★☆☆☆ |
| CHLOROGENIC ACID | 3 supporting sources | ★★☆☆☆ |
| Flavonoids | 3 supporting sources | ★★☆☆☆ |
| Lupulone | 3 supporting sources | ★★☆☆☆ |
| MYRCENE | 3 supporting sources | ★★☆☆☆ |
| RUTIN | 3 supporting sources | ★★☆☆☆ |
Xanthohumol
- Dr. Duke
- Pharmaceutical patent analyst
- Plants (Basel, Switzerland)
- Foods (Basel, Switzerland)
- Journal of natural products
View 14 additional sources
- Cancer prevention research (Philadelphia, Pa.)
- PloS one
- The Journal of clinical endocrinology and metabolism
- Bulletin of experimental biology and medicine
- Molecular nutrition & food research
- Chemico-biological interactions
- Pharmaceuticals (Basel, Switzerland)
- Chemical research in toxicology
- Planta medica
- Molecules (Basel, Switzerland)
- Journal of agricultural and food chemistry
- International journal of molecular sciences
- Biomedical chromatography : BMC
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
8-Prenylnaringenin
- Planta medica
- Journal of natural products
- Cancer prevention research (Philadelphia, Pa.)
- PloS one
- The Journal of clinical endocrinology and metabolism
View 7 additional sources
- Drug metabolism and disposition: the biological fate of chemicals
- Molecular nutrition & food research
- The Journal of steroid biochemistry and molecular biology
- Chemical research in toxicology
- International journal of molecular sciences
- Biomedical chromatography : BMC
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Isoxanthohumol
- Dr. Duke
- Journal of natural products
- The Journal of clinical endocrinology and metabolism
- Bulletin of experimental biology and medicine
- Planta medica
View 3 additional sources
- Biomedical chromatography : BMC
- International journal of molecular sciences
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
polyphenols
- Food chemistry
- Plants (Basel, Switzerland)
- Foods (Basel, Switzerland)
- Fitoterapia
- Bioscience, biotechnology, and biochemistry
6-Prenylnaringenin
- Journal of natural products
- The Journal of clinical endocrinology and metabolism
- Planta medica
- Biomedical chromatography : BMC
CHLOROGENIC ACID
- Dr. Duke
- Foods (Basel, Switzerland)
- Molecules (Basel, Switzerland)
Flavonoids
- Foods (Basel, Switzerland)
- Molecules (Basel, Switzerland)
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Lupulone
- Dr. Duke
- Foods (Basel, Switzerland)
- Journal of natural products
MYRCENE
- Dr. Duke
- Pharmaceuticals (Basel, Switzerland)
- Plant biology (Stuttgart, Germany)
RUTIN
- Dr. Duke
- Fitoterapia
- Pharmaceuticals (Basel, Switzerland)
Activities
Humulus lupulus has 731 reported activities identified across 4 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Estrogenic, Anticancer, Antimicrobial, Sedative.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Antioxidant | Dr. Duke (and other 7 sources) | ★★★★☆ |
| Estrogenic | Dr. Duke (and other 6 sources) | ★★★☆☆ |
| Anticancer | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Antimicrobial | Pharmaceutical patent analyst (and other 4 sources) | ★★☆☆☆ |
| Sedative | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Antibacterial | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Anticarcinogenic | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Antiproliferative | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Antiviral | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Analgesic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
Medicinal Uses
Humulus lupulus has 49 reported medicinal uses identified across 4 scientific publications and several other databases. The most consistently reported uses include anxiety, depression, cancer, inflammation, insomnia.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| anxiety | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 8 sources) | ★★★★☆ |
| depression | Phytomedicine : international journal of phytotherapy and phytopharmacology (and other 5 sources) | ★★★☆☆ |
| cancer | Journal of mass spectrometry : JMS (and other 3 sources) | ★★☆☆☆ |
| inflammation | International journal of molecular sciences (and other 3 sources) | ★★☆☆☆ |
| insomnia | Revista de enfermeria (Barcelona, Spain) (and other 3 sources) | ★★☆☆☆ |
| cardiovascular disease | Pharmaceutical patent analyst (and other 2 sources) | ★☆☆☆☆ |
| diabetes mellitus | Journal of natural products (and other 2 sources) | ★☆☆☆☆ |
| hot flashes | European review for medical and pharmacological sciences (and other 2 sources) | ★☆☆☆☆ |
| obesity | Pharmaceutical patent analyst (and other 2 sources) | ★☆☆☆☆ |
| primary insomnia | Indian journal of pharmacology (and other 2 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| ethanol extracts | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (and other 2 sources) | ★☆☆☆☆ |
| extracts | Analytical and bioanalytical chemistry (and other 2 sources) | ★☆☆☆☆ |
| plant extracts | Antibiotics (Basel, Switzerland) (and other 2 sources) | ★☆☆☆☆ |
| aqueous extract | Fitoterapia (and other 1 sources) | ★☆☆☆☆ |
| aqueous-methanolic extract (1:1; v/v) | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (and other 1 sources) | ★☆☆☆☆ |
| brewing | Journal of biomedicine & biotechnology (and other 1 sources) | ★☆☆☆☆ |
| extract | Biomedical chromatography : BMC (and other 1 sources) | ★☆☆☆☆ |
| herbal extracts | Current pharmaceutical design (and other 1 sources) | ★☆☆☆☆ |
| hop cone extract | Platelets (and other 1 sources) | ★☆☆☆☆ |
| hops extract | Avicenna journal of phytomedicine (and other 1 sources) | ★☆☆☆☆ |