Devil Claws

Harpagophytum · Accepted scientific name

Scientific literature: Very Sparse (24 studies) · ★☆☆☆☆

Devil'aws, scientifically known as Harpagophytum, is a medicinal plant native to Southern Africa. Renowned for its potent anti-inflammatory properties, it is primarily used to alleviate joint pain and arthritis symptoms. This remarkable herb contains harpagoside, a bioactive compound that makes it a cornerstone of traditional and modern herbal medicine.

Family
Pedaliaceae
Native range
Africa
Parts used
Leaf · Root
Common names
Devil Claws
Scientific synonyms
Uncaria

Names and Synonyms

Common Names

Scientific Names

Accepted name

Harpagophytum

Synonyms

Regional and Traditional Names

Spanish:

  • Garra del diablo y parientes

German:

  • Afrikanische Teufelskralle
  • Afrikanische Teufelskrallen

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it falls under the order Lamiales and is a member of the family Pedaliaceae. It is specifically identified by the genus Harpagophytum.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Lamiales
Family Pedaliaceae
Genus Harpagophytum

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant is primarily distributed across various regions of Southern and South Tropical Africa. Specifically, it can be found growing in the landscapes of Angola and Mozambique. Its presence extends further into the territories of Zambia and Zimbabwe. Additionally, this medicinal species is located within the borders of Botswana. These diverse locations highlight its specific ecological niche within the southern portion of the continent.

Region Area
South Tropical Africa Angola
South Tropical Africa Mozambique
South Tropical Africa Zambia
South Tropical Africa Zimbabwe
Southern Africa Botswana
Southern Africa Cape Provinces
Southern Africa Caprivi Strip
Southern Africa Lesotho
Southern Africa Namibia
Southern Africa KwaZulu-Natal

Sources: The World Checklist of Vascular Plants (WCVP)

Plant Parts

Harpagophytum has 2 reported plant parts identified across 2 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, root.

Plant parts reported in Harpagophytum
Plant part Supporting sources Consensus
Leaf 1 supporting sources ★☆☆☆☆
Root 1 supporting sources ★☆☆☆☆

Leaf

  1. Journal of ethnopharmacology

Root

  1. Annals of agricultural and environmental medicine : AAEM

Chemicals

Harpagophytum has 10 reported phytochemicals identified across 2 scientific publications and several other databases. The most consistently reported chemicals include Triterpenes, Coumarins, Flavonoids, Harpagide, Isorhynchophylline.

Chemicals reported in Harpagophytum
Chemical Supporting sources Consensus
Triterpenes 2 supporting sources ★☆☆☆☆
Coumarins 1 supporting sources ★☆☆☆☆
Flavonoids 1 supporting sources ★☆☆☆☆
Harpagide 1 supporting sources ★☆☆☆☆
Isorhynchophylline 1 supporting sources ★☆☆☆☆
Lignans 1 supporting sources ★☆☆☆☆
Rhynchophylline 1 supporting sources ★☆☆☆☆
Terpenes 1 supporting sources ★☆☆☆☆
Verbascoside 1 supporting sources ★☆☆☆☆
isoverbascoside 1 supporting sources ★☆☆☆☆

Triterpenes

  1. Phytochemistry
  2. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Coumarins

  1. Phytochemistry

Flavonoids

  1. Phytochemistry

Harpagide

  1. The journal of physical chemistry. A

Isorhynchophylline

  1. Molecules (Basel, Switzerland)

Lignans

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Rhynchophylline

  1. Molecules (Basel, Switzerland)

Terpenes

  1. Phytochemistry

Verbascoside

  1. Oxidative medicine and cellular longevity

isoverbascoside

  1. Oxidative medicine and cellular longevity

Activities

Harpagophytum has 6 reported activities identified across 2 scientific publications and several other databases. The most consistently reported activities include Antibacterial, Antiinflammatory, Antioxidant, Antiviral, Depressant.

Activities reported in Harpagophytum
Activity Supporting sources Consensus
Antibacterial 1 supporting sources ★☆☆☆☆
Antiinflammatory 1 supporting sources ★☆☆☆☆
Antioxidant 1 supporting sources ★☆☆☆☆
Antiviral 1 supporting sources ★☆☆☆☆
Depressant 1 supporting sources ★☆☆☆☆
Hypotensive 1 supporting sources ★☆☆☆☆

Antibacterial

  1. Phytochemistry

Antiinflammatory

  1. The journal of physical chemistry. A

Antioxidant

  1. Phytochemistry

Antiviral

  1. Phytochemistry

Depressant

  1. Journal of ethnopharmacology

Hypotensive

  1. Phytochemistry

Preparations

Preparations Sources Consensus
Harpagophytum preparations Phytotherapy research : PTR (and other 1 sources) ★☆☆☆☆
Uncaria Hook Plant biotechnology (Tokyo, Japan) (and other 1 sources) ★☆☆☆☆
capsule extract BMC genomics (and other 1 sources) ★☆☆☆☆
dry powdered extracts Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
essential oil Journal of oleo science (and other 1 sources) ★☆☆☆☆
extract from the root Annals of agricultural and environmental medicine : AAEM (and other 1 sources) ★☆☆☆☆
herbal supplement Annals of agricultural and environmental medicine : AAEM (and other 1 sources) ★☆☆☆☆
traditional Chinese medicine Pharmaceutical biology (and other 1 sources) ★☆☆☆☆