Gymnanthemum amygdalinum

Gymnanthemum amygdalinum · Accepted scientific name

Scientific literature: Very Extensive (226 studies) · ★★★★★

Gymnanthemum amygdalinum, scientifically known as Gymnanthemum amygdalinum, is a versatile medicinal plant widely utilized in traditional African medicine. Renowned for its profound therapeutic properties, it is frequently employed to manage diabetes, enhance digestion, and combat infections, offering a natural approach to holistic health and wellness through its bioactive compounds.

Family
Asteraceae
Native range
Africa
Parts used
Leaf · Root
Common names
Not available
Scientific synonyms
Bracheilema Paniculatum · Cacalia Amygdalina · 13 more

Names and Synonyms

Scientific Names

Accepted name

Gymnanthemum amygdalinum

Synonyms

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Asterales, it is classified under the family Asteraceae. Specifically, it is identified by the genus Gymnanthemum.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Asterales
Family Asteraceae
Genus Gymnanthemum

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, Gymnanthemum amygdalinum, is primarily found within the diverse landscapes of West Tropical Africa. Its natural habitat extends across several key nations, including Benin and Burkina Faso. Additionally, the species is documented to grow within the borders of Guinea. The plant also maintains a presence in the Ivory Coast, contributing to its regional importance. Finally, its geographical range is completed by its distribution in Liberia.

Region Area
West Tropical Africa Benin
West Tropical Africa Burkina
West Tropical Africa Guinea
West Tropical Africa Ivory Coast
West Tropical Africa Liberia
West Tropical Africa Mali
West Tropical Africa Nigeria
West Tropical Africa Sierra Leone
West Tropical Africa Togo
West-Central Tropical Africa Central African Republic

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Gymnema amygdalinum is characterized by its existence as a perennial plant, allowing it to persist through multiple growing seasons. In terms of its structural growth habit, it is classified as a phanerophyte, specifically exhibiting a phanerophyte life form where its perennially renewing buds are elevated above the ground level. Furthermore, the plant maintains an evergreen deciduousness, ensuring that its foliage remains functional and present throughout its life cycle rather than shedding all leaves seasonally.

Deciduousness :
evergreen
Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Gymnanthemum amygdalinum is characterized by a woody growth form that can manifest as both a shrub and a tree. As a terrestrial and independent species, it does not function as a parasite or an epiphyte, maintaining a self-supporting structure. The plant exhibits significant variation in stature, with heights ranging from a minimum of 0.5 m to a maximum of approximately 4.57 m, resulting in a mean plant height of 9 m across its observed developmental range.

Aquatic :
terrestrial
Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
shrub
Growth form :
tree
Parasite :
independent
Plant height max:
4.572055596 m
Plant height mean:
9 m
Plant height min:
0.5 m
Woodiness :
woody

Physiology

The physiology of Gymnema amygdalinum is characterized by specialized metabolic pathways focused on the synthesis of bioactive triterpenoid saponins, most notably gymnemic acids, which play a critical role in its interaction with glucose homeostasis. The plant undergoes complex photosynthetic processes to drive the production of these secondary metabolites, which are sequestered within its leaves and tissues. In terms of its nutrient acquisition and symbiotic relationships, the plant does not function as a nitrogen fixer; it lacks the specialized root nodules containing nitrogen-fixing bacteria required to convert atmospheric nitrogen into ammonia, meaning it relies on the uptake of nitrates and ammonium from the soil through its root system. Its physiological efficiency is largely defined by its ability to manage carbon assimilation and the subsequent biosynthesis of bitter principles that influence its chemical defense mechanisms and therapeutic properties.

Nitrogen fixer :
no

Reproduction

The reproduction of Gymnanthemum amygdalinum is characterized by the production of specialized seeds that exhibit significant variability in weight, with a minimum seed mass of 0.00049 g, a maximum of 0.00086 g, and an average seed mass of approximately 0.000675 g. Regarding its dispersal strategy, the plant utilizes an anemochorous syndrome, meaning its seeds are primarily adapted for dispersal via wind currents.

Dispersal syndrome :
anemochorous
Seed mass max:
0.00086 g
Seed mass mean:
0.000675 g
Seed mass min:
0.00049 g

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Gymnanthemum amygdalinum has 3 reported plant parts identified across 52 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, root, stem.

Plant parts reported in Gymnanthemum amygdalinum
Plant part Supporting sources Consensus
Leaf 44 supporting sources ★★★★★
Root 5 supporting sources ★★★☆☆
Stem 3 supporting sources ★★☆☆☆

Leaf

  1. Journal of complementary & integrative medicine
  2. African health sciences
  3. Environmental monitoring and assessment
  4. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
  5. Journal of chemical ecology
View 39 additional sources
  1. Plant foods for human nutrition (Dordrecht, Netherlands)
  2. Journal of food biochemistry
  3. World journal of diabetes
  4. Journal of medicinal food
  5. Pharmaceuticals (Basel, Switzerland)
  6. FEMS microbiology letters
  7. Plants (Basel, Switzerland)
  8. Journal of ethnopharmacology
  9. Biotechnology and applied biochemistry
  10. Journal of parasitology research
  11. Food science & nutrition
  12. Drug metabolism and personalized therapy
  13. Journal of environmental and public health
  14. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  15. Journal of experimental pharmacology
  16. Phytomedicine : international journal of phytotherapy and phytopharmacology
  17. Scientific reports
  18. Natural product research
  19. Journal of intercultural ethnopharmacology
  20. Advanced pharmaceutical bulletin
  21. BMC complementary and alternative medicine
  22. Phytotherapy research : PTR
  23. Frontiers in bioscience (Elite edition)
  24. Bratislavske lekarske listy
  25. Evidence-based complementary and alternative medicine : eCAM
  26. Journal of basic and clinical pharmacy
  27. Journal of ethnobiology and ethnomedicine
  28. Journal of diabetes research
  29. Veterinary world
  30. Journal of xenobiotics
  31. The Journal of pharmacy and pharmacology
  32. Tropical medicine and health
  33. Malaria research and treatment
  34. Pakistan journal of biological sciences : PJBS
  35. Chinese journal of natural medicines
  36. PeerJ
  37. Malaria journal
  38. Journal of the South African Veterinary Association
  39. Planta medica

Root

  1. Heliyon
  2. Bratislavske lekarske listy
  3. BMC complementary and alternative medicine
  4. The Journal of pharmacy and pharmacology
  5. BMC veterinary research

Stem

  1. Journal of chemical ecology
  2. Heliyon
  3. Bratislavske lekarske listy

Chemicals

Gymnanthemum amygdalinum has 77 reported phytochemicals identified across 52 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Tannins, VERNODALIN, VERNOLIDE, Vernodalol.

Chemicals reported in Gymnanthemum amygdalinum
Chemical Supporting sources Consensus
Flavonoids 7 supporting sources ★★★★☆
Tannins 3 supporting sources ★★☆☆☆
VERNODALIN 3 supporting sources ★★☆☆☆
VERNOLIDE 3 supporting sources ★★☆☆☆
Vernodalol 3 supporting sources ★★☆☆☆
Vernonioside B1 3 supporting sources ★★☆☆☆
luteolin 3 supporting sources ★★☆☆☆
CADMIUM 2 supporting sources ★☆☆☆☆
CHLOROGENIC ACID 2 supporting sources ★☆☆☆☆
CHROMIUM 2 supporting sources ★☆☆☆☆

Flavonoids

  1. World journal of diabetes
  2. Evidence-based complementary and alternative medicine : eCAM
  3. Biotechnology and applied biochemistry
  4. International journal of environmental research and public health
  5. Journal of diabetes research
View 2 additional sources
  1. Chemistry & biodiversity
  2. PeerJ

Tannins

  1. World journal of diabetes
  2. Biotechnology and applied biochemistry
  3. Journal of parasitology research

VERNODALIN

  1. Journal of chemical ecology
  2. Physiology & behavior
  3. Computational toxicology (Amsterdam, Netherlands)

VERNOLIDE

  1. Physiology & behavior
  2. Computational toxicology (Amsterdam, Netherlands)
  3. Malaria journal

Vernodalol

  1. The Journal of pharmacy and pharmacology
  2. Computational toxicology (Amsterdam, Netherlands)
  3. Malaria journal

Vernonioside B1

  1. Journal of chemical ecology
  2. Physiology & behavior
  3. Natural product research

luteolin

  1. Journal of ethnopharmacology
  2. Phytotherapy research : PTR
  3. The Journal of pharmacy and pharmacology

CADMIUM

  1. Journal of toxicology
  2. Environmental monitoring and assessment

CHLOROGENIC ACID

  1. Journal of ethnopharmacology
  2. The Journal of pharmacy and pharmacology

CHROMIUM

  1. Journal of toxicology
  2. Environmental monitoring and assessment

Activities

Gymnanthemum amygdalinum has 20 reported activities identified across 52 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antidiabetic, Analgesic, Anthelmintic, Antimalarial.

Activities reported in Gymnanthemum amygdalinum
Activity Supporting sources Consensus
Antioxidant 10 supporting sources ★★★★★
Antidiabetic 8 supporting sources ★★★★☆
Analgesic 3 supporting sources ★★☆☆☆
Anthelmintic 2 supporting sources ★☆☆☆☆
Antimalarial 2 supporting sources ★☆☆☆☆
Antiplasmodial 2 supporting sources ★☆☆☆☆
Hypoglycemic 2 supporting sources ★☆☆☆☆
Antibacterial 1 supporting sources ★☆☆☆☆
Anticancer 1 supporting sources ★☆☆☆☆
Antiglycation 1 supporting sources ★☆☆☆☆

Antioxidant

  1. Experimental biology and medicine (Maywood, N.J.)
  2. Journal of food biochemistry
  3. Pakistan journal of pharmaceutical sciences
  4. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  5. Molecules (Basel, Switzerland)
View 5 additional sources
  1. Scientific reports
  2. Avicenna journal of phytomedicine
  3. The Journal of pharmacy and pharmacology
  4. Chemistry & biodiversity
  5. Tropical medicine and health

Antidiabetic

  1. Journal of ethnopharmacology
  2. Journal of food biochemistry
  3. Journal of intercultural ethnopharmacology
  4. Journal of basic and clinical pharmacy
  5. Journal of diabetes research
View 3 additional sources
  1. Journal of xenobiotics
  2. The Journal of pharmacy and pharmacology
  3. Tropical medicine and health

Analgesic

  1. Phytotherapy research : PTR
  2. Advanced pharmaceutical bulletin
  3. Planta medica

Anthelmintic

  1. Veterinary parasitology
  2. Journal of intercultural ethnopharmacology

Antimalarial

  1. Journal of intercultural ethnopharmacology
  2. Scientifica

Antiplasmodial

  1. Journal of ethnopharmacology
  2. Avicenna journal of phytomedicine

Hypoglycemic

  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. Chemistry & biodiversity

Antibacterial

  1. Journal of toxicology

Anticancer

  1. Experimental biology and medicine (Maywood, N.J.)

Antiglycation

  1. The Journal of pharmacy and pharmacology

Preparations

Preparations Sources Consensus
extracts Journal of tropical medicine (and other 4 sources) ★★☆☆☆
leaf extract Journal of complementary & integrative medicine (and other 4 sources) ★★☆☆☆
crude extract Journal of experimental pharmacology (and other 3 sources) ★★☆☆☆
ethyl acetate extract Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society (and other 2 sources) ★☆☆☆☆
extract Scientific reports (and other 2 sources) ★☆☆☆☆
leaves Veterinary world (and other 2 sources) ★☆☆☆☆
powder Journal of environmental and public health (and other 2 sources) ★☆☆☆☆
80% acetone extract Plant foods for human nutrition (Dordrecht, Netherlands) (and other 1 sources) ★☆☆☆☆
80% methanol leaves extract Journal of experimental pharmacology (and other 1 sources) ★☆☆☆☆
Acetone extract Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆