Gymnanthemum amygdalinum
Gymnanthemum amygdalinum · Accepted scientific name
Scientific literature: Very Extensive (226 studies) · ★★★★★
Gymnanthemum amygdalinum, scientifically known as Gymnanthemum amygdalinum, is a versatile medicinal plant widely utilized in traditional African medicine. Renowned for its profound therapeutic properties, it is frequently employed to manage diabetes, enhance digestion, and combat infections, offering a natural approach to holistic health and wellness through its bioactive compounds.
- Family
- Asteraceae
- Native range
- Africa
- Parts used
- Leaf · Root
- Common names
- Not available
- Scientific synonyms
- Bracheilema Paniculatum · Cacalia Amygdalina · 13 more
Names and Synonyms
Scientific Names
Accepted name
Gymnanthemum amygdalinumSynonyms
- Bracheilema paniculatum
- Cacalia amygdalina
- Decaneurum amygdalinum
- Gymnanthemum abyssinicum
- Keringa amygdalina
- Vernonanthura condensata
- Vernonia adenosticta
- Vernonia amygdalina
- Vernonia bahiensis
- Vernonia condensata
- Vernonia eritreana
- Vernonia giorgii
- Vernonia randii
- Vernonia vogeliana
- Vernonia weisseana
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Asterales, it is classified under the family Asteraceae. Specifically, it is identified by the genus Gymnanthemum.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Asterales |
| Family | Asteraceae |
| Genus | Gymnanthemum |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant, Gymnanthemum amygdalinum, is primarily found within the diverse landscapes of West Tropical Africa. Its natural habitat extends across several key nations, including Benin and Burkina Faso. Additionally, the species is documented to grow within the borders of Guinea. The plant also maintains a presence in the Ivory Coast, contributing to its regional importance. Finally, its geographical range is completed by its distribution in Liberia.
| Region | Area |
|---|---|
| West Tropical Africa | Benin |
| West Tropical Africa | Burkina |
| West Tropical Africa | Guinea |
| West Tropical Africa | Ivory Coast |
| West Tropical Africa | Liberia |
| West Tropical Africa | Mali |
| West Tropical Africa | Nigeria |
| West Tropical Africa | Sierra Leone |
| West Tropical Africa | Togo |
| West-Central Tropical Africa | Central African Republic |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Gymnema amygdalinum is characterized by its existence as a perennial plant, allowing it to persist through multiple growing seasons. In terms of its structural growth habit, it is classified as a phanerophyte, specifically exhibiting a phanerophyte life form where its perennially renewing buds are elevated above the ground level. Furthermore, the plant maintains an evergreen deciduousness, ensuring that its foliage remains functional and present throughout its life cycle rather than shedding all leaves seasonally.
- Deciduousness :
- evergreen
- Life form :
- phanerophyte
- Lifecycle :
- perennial
Morphology
The morphology of Gymnanthemum amygdalinum is characterized by a woody growth form that can manifest as both a shrub and a tree. As a terrestrial and independent species, it does not function as a parasite or an epiphyte, maintaining a self-supporting structure. The plant exhibits significant variation in stature, with heights ranging from a minimum of 0.5 m to a maximum of approximately 4.57 m, resulting in a mean plant height of 9 m across its observed developmental range.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- shrub
- Growth form :
- tree
- Parasite :
- independent
- Plant height max:
- 4.572055596 m
- Plant height mean:
- 9 m
- Plant height min:
- 0.5 m
- Woodiness :
- woody
Physiology
The physiology of Gymnema amygdalinum is characterized by specialized metabolic pathways focused on the synthesis of bioactive triterpenoid saponins, most notably gymnemic acids, which play a critical role in its interaction with glucose homeostasis. The plant undergoes complex photosynthetic processes to drive the production of these secondary metabolites, which are sequestered within its leaves and tissues. In terms of its nutrient acquisition and symbiotic relationships, the plant does not function as a nitrogen fixer; it lacks the specialized root nodules containing nitrogen-fixing bacteria required to convert atmospheric nitrogen into ammonia, meaning it relies on the uptake of nitrates and ammonium from the soil through its root system. Its physiological efficiency is largely defined by its ability to manage carbon assimilation and the subsequent biosynthesis of bitter principles that influence its chemical defense mechanisms and therapeutic properties.
- Nitrogen fixer :
- no
Reproduction
The reproduction of Gymnanthemum amygdalinum is characterized by the production of specialized seeds that exhibit significant variability in weight, with a minimum seed mass of 0.00049 g, a maximum of 0.00086 g, and an average seed mass of approximately 0.000675 g. Regarding its dispersal strategy, the plant utilizes an anemochorous syndrome, meaning its seeds are primarily adapted for dispersal via wind currents.
- Dispersal syndrome :
- anemochorous
- Seed mass max:
- 0.00086 g
- Seed mass mean:
- 0.000675 g
- Seed mass min:
- 0.00049 g
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Gymnanthemum amygdalinum has 3 reported plant parts identified across 52 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include leaf, root, stem.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Leaf | 44 supporting sources | ★★★★★ |
| Root | 5 supporting sources | ★★★☆☆ |
| Stem | 3 supporting sources | ★★☆☆☆ |
Leaf
- Journal of complementary & integrative medicine
- African health sciences
- Environmental monitoring and assessment
- Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
- Journal of chemical ecology
View 39 additional sources
- Plant foods for human nutrition (Dordrecht, Netherlands)
- Journal of food biochemistry
- World journal of diabetes
- Journal of medicinal food
- Pharmaceuticals (Basel, Switzerland)
- FEMS microbiology letters
- Plants (Basel, Switzerland)
- Journal of ethnopharmacology
- Biotechnology and applied biochemistry
- Journal of parasitology research
- Food science & nutrition
- Drug metabolism and personalized therapy
- Journal of environmental and public health
- Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
- Journal of experimental pharmacology
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Scientific reports
- Natural product research
- Journal of intercultural ethnopharmacology
- Advanced pharmaceutical bulletin
- BMC complementary and alternative medicine
- Phytotherapy research : PTR
- Frontiers in bioscience (Elite edition)
- Bratislavske lekarske listy
- Evidence-based complementary and alternative medicine : eCAM
- Journal of basic and clinical pharmacy
- Journal of ethnobiology and ethnomedicine
- Journal of diabetes research
- Veterinary world
- Journal of xenobiotics
- The Journal of pharmacy and pharmacology
- Tropical medicine and health
- Malaria research and treatment
- Pakistan journal of biological sciences : PJBS
- Chinese journal of natural medicines
- PeerJ
- Malaria journal
- Journal of the South African Veterinary Association
- Planta medica
Root
- Heliyon
- Bratislavske lekarske listy
- BMC complementary and alternative medicine
- The Journal of pharmacy and pharmacology
- BMC veterinary research
Stem
- Journal of chemical ecology
- Heliyon
- Bratislavske lekarske listy
Chemicals
Gymnanthemum amygdalinum has 77 reported phytochemicals identified across 52 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Tannins, VERNODALIN, VERNOLIDE, Vernodalol.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Flavonoids | 7 supporting sources | ★★★★☆ |
| Tannins | 3 supporting sources | ★★☆☆☆ |
| VERNODALIN | 3 supporting sources | ★★☆☆☆ |
| VERNOLIDE | 3 supporting sources | ★★☆☆☆ |
| Vernodalol | 3 supporting sources | ★★☆☆☆ |
| Vernonioside B1 | 3 supporting sources | ★★☆☆☆ |
| luteolin | 3 supporting sources | ★★☆☆☆ |
| CADMIUM | 2 supporting sources | ★☆☆☆☆ |
| CHLOROGENIC ACID | 2 supporting sources | ★☆☆☆☆ |
| CHROMIUM | 2 supporting sources | ★☆☆☆☆ |
Flavonoids
- World journal of diabetes
- Evidence-based complementary and alternative medicine : eCAM
- Biotechnology and applied biochemistry
- International journal of environmental research and public health
- Journal of diabetes research
View 2 additional sources
- Chemistry & biodiversity
- PeerJ
Tannins
- World journal of diabetes
- Biotechnology and applied biochemistry
- Journal of parasitology research
VERNODALIN
- Journal of chemical ecology
- Physiology & behavior
- Computational toxicology (Amsterdam, Netherlands)
VERNOLIDE
- Physiology & behavior
- Computational toxicology (Amsterdam, Netherlands)
- Malaria journal
Vernodalol
- The Journal of pharmacy and pharmacology
- Computational toxicology (Amsterdam, Netherlands)
- Malaria journal
Vernonioside B1
- Journal of chemical ecology
- Physiology & behavior
- Natural product research
luteolin
- Journal of ethnopharmacology
- Phytotherapy research : PTR
- The Journal of pharmacy and pharmacology
CADMIUM
- Journal of toxicology
- Environmental monitoring and assessment
CHLOROGENIC ACID
- Journal of ethnopharmacology
- The Journal of pharmacy and pharmacology
CHROMIUM
- Journal of toxicology
- Environmental monitoring and assessment
Activities
Gymnanthemum amygdalinum has 20 reported activities identified across 52 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antidiabetic, Analgesic, Anthelmintic, Antimalarial.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 10 supporting sources | ★★★★★ |
| Antidiabetic | 8 supporting sources | ★★★★☆ |
| Analgesic | 3 supporting sources | ★★☆☆☆ |
| Anthelmintic | 2 supporting sources | ★☆☆☆☆ |
| Antimalarial | 2 supporting sources | ★☆☆☆☆ |
| Antiplasmodial | 2 supporting sources | ★☆☆☆☆ |
| Hypoglycemic | 2 supporting sources | ★☆☆☆☆ |
| Antibacterial | 1 supporting sources | ★☆☆☆☆ |
| Anticancer | 1 supporting sources | ★☆☆☆☆ |
| Antiglycation | 1 supporting sources | ★☆☆☆☆ |
Antioxidant
- Experimental biology and medicine (Maywood, N.J.)
- Journal of food biochemistry
- Pakistan journal of pharmaceutical sciences
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Molecules (Basel, Switzerland)
View 5 additional sources
- Scientific reports
- Avicenna journal of phytomedicine
- The Journal of pharmacy and pharmacology
- Chemistry & biodiversity
- Tropical medicine and health
Antidiabetic
- Journal of ethnopharmacology
- Journal of food biochemistry
- Journal of intercultural ethnopharmacology
- Journal of basic and clinical pharmacy
- Journal of diabetes research
View 3 additional sources
- Journal of xenobiotics
- The Journal of pharmacy and pharmacology
- Tropical medicine and health
Analgesic
- Phytotherapy research : PTR
- Advanced pharmaceutical bulletin
- Planta medica
Anthelmintic
- Veterinary parasitology
- Journal of intercultural ethnopharmacology
Antimalarial
- Journal of intercultural ethnopharmacology
- Scientifica
Antiplasmodial
- Journal of ethnopharmacology
- Avicenna journal of phytomedicine
Hypoglycemic
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Chemistry & biodiversity
Antibacterial
- Journal of toxicology
Anticancer
- Experimental biology and medicine (Maywood, N.J.)
Antiglycation
- The Journal of pharmacy and pharmacology
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| extracts | Journal of tropical medicine (and other 4 sources) | ★★☆☆☆ |
| leaf extract | Journal of complementary & integrative medicine (and other 4 sources) | ★★☆☆☆ |
| crude extract | Journal of experimental pharmacology (and other 3 sources) | ★★☆☆☆ |
| ethyl acetate extract | Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society (and other 2 sources) | ★☆☆☆☆ |
| extract | Scientific reports (and other 2 sources) | ★☆☆☆☆ |
| leaves | Veterinary world (and other 2 sources) | ★☆☆☆☆ |
| powder | Journal of environmental and public health (and other 2 sources) | ★☆☆☆☆ |
| 80% acetone extract | Plant foods for human nutrition (Dordrecht, Netherlands) (and other 1 sources) | ★☆☆☆☆ |
| 80% methanol leaves extract | Journal of experimental pharmacology (and other 1 sources) | ★☆☆☆☆ |
| Acetone extract | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |