Chinese licorice
Glycyrrhiza inflata · Accepted scientific name
Scientific literature: Moderate (126 studies) · ★★★☆☆
Chinese licorice, scientifically known as Glycyrrhiza inflata, is a potent medicinal herb deeply rooted in traditional Eastern practices. Renowned for its soothing properties, it is frequently utilized to alleviate respiratory issues, reduce inflammation, and support digestive health. This versatile plant offers significant therapeutic benefits through its unique bioactive compounds.
- Family
- Fabaceae
- Native range
- Asia-Temperate
- Parts used
- Root · Rhizome
- Common names
- Chinese Licorice
- Scientific synonyms
- Glycyrrhiza Glabra Var. Inflata · Meristotropis Paucifoliolata · 3 more
Names and Synonyms
Common Names
- Chinese licorice
Scientific Names
Accepted name
Glycyrrhiza inflataSynonyms
- Glycyrrhiza glabra var. inflata
- Meristotropis paucifoliolata
- Glycyrrhiza hediniana
- Glycyrrhiza eurycarpa
- Glycyrrhiza paucifoliolata
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Fabales, it is a member of the Fabaceae family. Specifically, it is classified under the genus Glycyrrhiza as the species Glycyrrhiza inflata.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Fabales |
| Family | Fabaceae |
| Genus | Glycyrrhiza |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a specific geographical distribution primarily centered within East and Central Asia. In China, its presence is notable across the Inner Mongolia region. It is also found throughout the China North-Central territories, demonstrating a broad reach within the country. Furthermore, the species extends into the Xinjiang region of China. Finally, its habitat encompasses the neighboring nation of Mongolia.
| Region | Area |
|---|---|
| China | Inner Mongolia |
| China | China North-Central |
| China | Xinjiang |
| Mongolia | Mongolia |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Glycyrrhiza inflata is characterized by its classification as a perennial species, meaning it lives for more than two years and undergoes repeated cycles of growth and dormancy. As a perennial herb, the plant establishes a robust, woody rootstock that allows it to persist through varying seasonal conditions, storing energy to support regrowth in subsequent years. Its development involves a cyclical pattern where it emerges from the soil, produces vegetative structures, and enters a reproductive phase. During its life cycle, it produces inflorescences that facilitate sexual reproduction via seeds, which contribute to the genetic diversity and dispersal of the species, while the perennial nature of its root system ensures long-term survival and establishment within its ecological niche.
- Lifecycle :
- perennial
Morphology
The morphology of Glycyrrhiza inflata is characterized by a growth form categorized as a herb, specifically presenting as a non-woody, herbaceous plant. It functions as an independent organism, lacking any parasitic or epiphytic tendencies, and maintains a strictly terrestrial lifestyle rather than being aquatic or semiaquatic. In terms of its structural habit, the plant is self-supporting, meaning it does not exhibit the climbing characteristics of a liana, vine, or any other obligatory or facultative climber.
- Aquatic :
- terrestrial
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Parasite :
- independent
- Woodiness :
- non-woody
Physiology
The physiology of Glycyrrhiza inflata is characterized by a metabolic framework governed by a C3 photosynthetic pathway, which dictates its carbon fixation processes and resource utilization strategies. As a C3 plant, it fixes atmospheric carbon dioxide directly through the enzyme Rubisco during the Calvin cycle, occurring within the mesophyll cells without the specialized anatomical adaptations seen in C4 or CAM species. This photosynthetic mode implies that the plant's gas exchange and energy production are highly sensitive to environmental variables such as light intensity, temperature, and water availability. Under optimal conditions, its physiological efficiency is optimized for temperate or Mediterranean-like climates where moisture is sufficient to support stomatal conductance without excessive transpirational loss. Furthermore, the plant's metabolic activity supports the synthesis of complex secondary metabolites, a process intrinsically linked to its primary carbon assimilation and the energetic flux derived from its C3 carbon fixation cycle.
- Photosynthetic pathway :
- C3
Reproduction
Reproduction in Glycyrrhiza inflata is facilitated through the production of seeds, which exhibit highly consistent morphological characteristics regarding their weight. The reproductive output is characterized by a uniform seed mass, with a mean value of 0.01029 g. This consistency is reflected across the entire measured range, as both the maximum and minimum seed mass values are recorded at exactly 0.01029 g. This lack of variance in seed mass suggests a highly standardized developmental process during the maturation of the seeds within the plant's reproductive structures.
- Seed mass mean:
- 0.01029 g
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Glycyrrhiza inflata has 2 reported plant parts identified across 11 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, rhizome.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 10 supporting sources | ★★★★★ |
| Rhizome | 1 supporting sources | ★☆☆☆☆ |
Root
- Planta medica
- Molecules (Basel, Switzerland)
- The Journal of pharmacy and pharmacology
- Phytochemistry
- PeerJ
View 5 additional sources
- BMC plant biology
- BMC microbiology
- Bioorganic & medicinal chemistry
- Fitoterapia
- Cells
Rhizome
- Phytochemistry
Chemicals
Glycyrrhiza inflata has 37 reported phytochemicals identified across 11 scientific publications and several other databases. The most consistently reported chemicals include licochalcone a, glycyrrhizin, Licochalcone D, Flavonoids, Liquiritin.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| licochalcone a | 12 supporting sources | ★★★★★ |
| glycyrrhizin | 5 supporting sources | ★★★☆☆ |
| Licochalcone D | 4 supporting sources | ★★☆☆☆ |
| Flavonoids | 3 supporting sources | ★★☆☆☆ |
| Liquiritin | 3 supporting sources | ★★☆☆☆ |
| isoliquiritigenin | 3 supporting sources | ★★☆☆☆ |
| Glycyrrhizic acid | 2 supporting sources | ★☆☆☆☆ |
| LICA | 2 supporting sources | ★☆☆☆☆ |
| Licochalcone B | 2 supporting sources | ★☆☆☆☆ |
| Licochalcone C | 2 supporting sources | ★☆☆☆☆ |
licochalcone a
- Planta medica
- The Journal of pharmacy and pharmacology
- Microbiology and immunology
- Phytochemistry
- Fitoterapia
View 7 additional sources
- Food & function
- Bioorganic & medicinal chemistry
- Chemical research in toxicology
- Life sciences
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Molecular horticulture
- Cells
glycyrrhizin
- Biological & pharmaceutical bulletin
- Plant & cell physiology
- Toxicology reports
- The Plant journal : for cell and molecular biology
- Phytochemistry
Licochalcone D
- Biomolecules
- Phytochemistry
- Food & function
- Bioorganic & medicinal chemistry
Flavonoids
- BMC plant biology
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Liquiritin
- Yao xue xue bao = Acta pharmaceutica Sinica
- PeerJ
- BMC microbiology
isoliquiritigenin
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Bioorganic & medicinal chemistry
- Chemical research in toxicology
Glycyrrhizic acid
- PeerJ
- BMC microbiology
LICA
- Fitoterapia
- Cancer prevention research (Philadelphia, Pa.)
Licochalcone B
- Phytochemistry
- Bioorganic & medicinal chemistry
Licochalcone C
- Phytochemistry
- Bioorganic & medicinal chemistry
Activities
Glycyrrhiza inflata has 11 reported activities identified across 11 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Chemopreventive, Hepatoprotective, Antiallergic, Anticancer.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antioxidant | 2 supporting sources | ★☆☆☆☆ |
| Chemopreventive | 2 supporting sources | ★☆☆☆☆ |
| Hepatoprotective | 2 supporting sources | ★☆☆☆☆ |
| Antiallergic | 1 supporting sources | ★☆☆☆☆ |
| Anticancer | 1 supporting sources | ★☆☆☆☆ |
| Antidiabetic | 1 supporting sources | ★☆☆☆☆ |
| Antimicrobial | 1 supporting sources | ★☆☆☆☆ |
| Antispasmodic | 1 supporting sources | ★☆☆☆☆ |
| Antiviral | 1 supporting sources | ★☆☆☆☆ |
| Hepatotoxic | 1 supporting sources | ★☆☆☆☆ |
Antioxidant
- Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
- Mini reviews in medicinal chemistry
Chemopreventive
- Chemical research in toxicology
- Cancer prevention research (Philadelphia, Pa.)
Hepatoprotective
- Molecules (Basel, Switzerland)
- Phytomedicine : international journal of phytotherapy and phytopharmacology
Antiallergic
- Mini reviews in medicinal chemistry
Anticancer
- Mini reviews in medicinal chemistry
Antidiabetic
- Mini reviews in medicinal chemistry
Antimicrobial
- Mini reviews in medicinal chemistry
Antispasmodic
- The Journal of pharmacy and pharmacology
Antiviral
- Mini reviews in medicinal chemistry
Hepatotoxic
- Mini reviews in medicinal chemistry
Medicinal Uses
Glycyrrhiza inflata has 20 reported medicinal uses identified across 11 scientific publications and several other databases. The most consistently reported uses include cancer, inflammation, Bacillus subtilis, Escherichia coli, Helicobacter pylori.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| cancer | Anti-cancer agents in medicinal chemistry (and other 2 sources) | ★☆☆☆☆ |
| inflammation | Chemical research in toxicology (and other 2 sources) | ★☆☆☆☆ |
| Bacillus subtilis | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| Escherichia coli | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| Helicobacter pylori | Life sciences (and other 1 sources) | ★☆☆☆☆ |
| Pseudomonas aeruginosa | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| Staphylococcus aureus | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| allergies | Mini reviews in medicinal chemistry (and other 1 sources) | ★☆☆☆☆ |
| hereditary ataxia | Chinese medicine (and other 1 sources) | ★☆☆☆☆ |
| lipid peroxidation | Bioorganic & medicinal chemistry (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| roots | Phytochemistry (and other 2 sources) | ★☆☆☆☆ |
| Licochalcone D | Biomolecules (and other 1 sources) | ★☆☆☆☆ |
| combined decoction of the single drug | Yao xue xue bao = Acta pharmaceutica Sinica (and other 1 sources) | ★☆☆☆☆ |
| decoctions of Glycyrrhiza inflata and Kansui | Yao xue xue bao = Acta pharmaceutica Sinica (and other 1 sources) | ★☆☆☆☆ |
| enzymatic extraction (EE) | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| food | Molecular horticulture (and other 1 sources) | ★☆☆☆☆ |
| herbal medicine | Molecular horticulture (and other 1 sources) | ★☆☆☆☆ |
| repeat freeze-dissolve extraction (FDE) | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| ultrasonic-assisted extraction (UAE) | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| water extract | Molecules (Basel, Switzerland) (and other 1 sources) | ★☆☆☆☆ |