maidenhair tree

Ginkgo biloba · Accepted scientific name

Scientific literature: Very Extensive (2603 studies) · ★★★★★

Maidenhair tree, scientifically known as Ginkgo biloba, is a living fossil with a history spanning millions of years. Renowned for its unique fan-shaped leaves, this resilient species is widely used in traditional medicine to support cognitive function, enhance memory, and improve circulation, offering profound benefits for brain health.

Family
Ginkgoaceae
Native range
Europe
Parts used
Leaf · Seed
Common names
Maidenhair-Tree · Gingko · 2 more
Scientific synonyms
Ginkgo Biloba F. Pendula · Ginkgo Biloba Var. Laciniata · 26 more

Names

Common Names

Regional and Traditional Names

Spanish:

  • Gingko
  • Ginko
  • Gingko biloba
  • Ginko biloba
  • Árbol de los cuarenta escudos
  • Arbol de los cuarenta escudos
  • Xinkgo
  • albaricoque de plata
  • árbol de doncella
  • planta de ginkgo
  • árbol de ginkgo
  • gingko
  • ginkgo
  • árbol de los cuarenta escudos
  • nogal del Japón
  • nogal de Japón
  • albaricoque plateado

German:

  • Ginkgo
  • Silberaprikose
  • Ginkgo biloba Linne
  • Fächerbaum
  • Ginkgobaum
  • Fächerblattbaum
  • Ginkgogewächse
  • Silberpflaume
  • Salisburia adiantifolia
  • Ginkyo
  • Ginkgobaum

French:

  • Gingkos
  • Arbre aux 40 écus
  • Arbre aux quarante écus
  • Gingko biloba
  • noyer du Japon
  • Arbre aux quarante écus

Scientific Names

Accepted name

Ginkgo biloba

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Ginkgoidae. It is uniquely positioned within the order Ginkgoales and the family Ginkgoaceae. Ultimately, it is classified under the single-species genus Ginkgo.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Ginkgoidae WCVP
Order Ginkgoales WCVP
Family Ginkgoaceae WCVP
Genus Ginkgo WCVP

Distribution

This plant exhibits a wide geographical distribution that spans across several distinct regions. In Asia, its natural range includes China South-Central, China North-Central, and China Southeast. Moving toward the European continent, the species can be found in Southeastern Europe, specifically within Romania. Additionally, the plant is present in Middle Europe, notably in Austria. These diverse locations highlight the plant's ability to establish itself across various environmental zones.

Region Area Source
Middle Europe Austria WCVP
Southeastern Europe Romania WCVP
China China South-Central WCVP
China China North-Central WCVP
China China Southeast WCVP
Eastern Asia Japan WCVP
Eastern Asia Korea WCVP
North-Central U.S.A. Illinois WCVP

Plant Parts

This plant, commonly known as the maidenhair tree, offers various components used in traditional and modern medicine. Most therapeutic applications focus on the leaves, as the dried leaf is often processed into a concentrated leaf extract to support cognitive function and blood circulation. While the seeds are also edible when prepared correctly, the seed itself contains different chemical compounds than the foliage, making the leaf-based preparations the most frequent choice for medicinal supplements.
Plant Part Sources Consensus
leaf Acta pharmacologica Sinica (and other 94 sources) ★★★★★
seed Biochimica et biophysica acta (and other 14 sources) ★★★★★
root Current microbiology (and other 5 sources) ★★★☆☆
fruit Plants (Basel, Switzerland) (and other 4 sources) ★★☆☆☆
stem Current microbiology (and other 3 sources) ★★☆☆☆

Chemicals

Ginkgo biloba has 387 reported phytochemicals identified across 120 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Bilobalide, quercetin, kaempferol, Ginkgolide B.

Chemicals reported in Ginkgo biloba
Chemical Supporting sources Consensus
Flavonoids 43 supporting sources ★★★★★
Bilobalide 36 supporting sources ★★★★★
quercetin 35 supporting sources ★★★★★
kaempferol 30 supporting sources ★★★★★
Ginkgolide B 28 supporting sources ★★★★★
Ginkgolide A 18 supporting sources ★★★★★
Ginkgolic acids 16 supporting sources ★★★★★
RUTIN 15 supporting sources ★★★★★
EGB 14 supporting sources ★★★★★
Terpenoids 14 supporting sources ★★★★★

Flavonoids

  1. Dr. Duke
  2. Tree physiology
  3. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
  4. Plant biology (Stuttgart, Germany)
  5. Metabolites
View 38 additional sources
  1. Evidence-based complementary and alternative medicine : eCAM
  2. Pharmacognosy reviews
  3. Planta medica
  4. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  5. Plants (Basel, Switzerland)
  6. BMC plant biology
  7. The American journal of Chinese medicine
  8. Journal of neurochemistry
  9. Molecules (Basel, Switzerland)
  10. Journal of agricultural and food chemistry
  11. CNS & neurological disorders drug targets
  12. Degenerative neurological and neuromuscular disease
  13. Journal of the science of food and agriculture
  14. Biochemistry and molecular biology international
  15. International journal of molecular sciences
  16. BioMed research international
  17. Lipids
  18. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  19. Frontiers in plant science
  20. Plant physiology and biochemistry : PPB
  21. Die Pharmazie
  22. Frontiers in genetics
  23. Journal of food science
  24. Gene
  25. Journal of separation science
  26. Nutrients
  27. Proteomics
  28. Chinese medicine
  29. The Journal of pharmacy and pharmacology
  30. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  31. Enzyme and microbial technology
  32. Recenti progressi in medicina
  33. Forestry research
  34. Current pharmaceutical design
  35. Current cardiology reviews
  36. Clinical pharmacokinetics
  37. Fitoterapia
  38. Journal of dietary supplements

Bilobalide

  1. Dr. Duke
  2. Current microbiology
  3. Journal of pharmaceutical and biomedical analysis
  4. Rapid communications in mass spectrometry : RCM
  5. Naunyn-Schmiedeberg's archives of pharmacology
View 31 additional sources
  1. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
  2. Journal of molecular modeling
  3. Brain research
  4. Journal of natural products
  5. Journal of AOAC International
  6. The American journal of Chinese medicine
  7. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
  8. The Journal of pharmacy and pharmacology
  9. Brazilian journal of biology = Revista brasleira de biologia
  10. Planta medica
  11. Journal of neurochemistry
  12. Physiologia plantarum
  13. Journal of chromatography. A
  14. International journal of molecular sciences
  15. Presse medicale (Paris, France : 1983)
  16. Molecules (Basel, Switzerland)
  17. Neurobiology of disease
  18. European journal of pharmacology
  19. Phytochemical analysis : PCA
  20. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
  21. Antimicrobial agents and chemotherapy
  22. Cells
  23. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  24. Mutation research
  25. Yao xue xue bao = Acta pharmaceutica Sinica
  26. Annales pharmaceutiques francaises
  27. Journal of ethnopharmacology
  28. Pharmacological research
  29. Clinica chimica acta; international journal of clinical chemistry
  30. Farmaco (Societa chimica italiana : 1989)
  31. Journal of mass spectrometry : JMS

quercetin

  1. Dr. Duke
  2. Journal of pharmaceutical and biomedical analysis
  3. Journal of separation science
  4. Biochemical pharmacology
  5. Molecules (Basel, Switzerland)
View 30 additional sources
  1. FEBS letters
  2. The American journal of Chinese medicine
  3. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
  4. Brazilian journal of biology = Revista brasleira de biologia
  5. National Toxicology Program technical report series
  6. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  7. Journal of chromatography. A
  8. Yao xue xue bao = Acta pharmaceutica Sinica
  9. Journal of AOAC International
  10. Biochemistry and molecular biology international
  11. Rapid communications in mass spectrometry : RCM
  12. Analytical and bioanalytical chemistry
  13. Acta clinica Croatica
  14. Lipids
  15. Journal of agricultural and food chemistry
  16. Journal of ethnopharmacology
  17. Acta pharmacologica Sinica
  18. Phytomedicine : international journal of phytotherapy and phytopharmacology
  19. The Journal of dermatology
  20. Foods (Basel, Switzerland)
  21. Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
  22. The Analyst
  23. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
  24. Forestry research
  25. The Journal of pharmacy and pharmacology
  26. Fitoterapia
  27. Clinica chimica acta; international journal of clinical chemistry
  28. Journal of chromatography. B, Biomedical sciences and applications
  29. Farmaco (Societa chimica italiana : 1989)
  30. Current issues in molecular biology

kaempferol

  1. Dr. Duke
  2. Journal of pharmaceutical and biomedical analysis
  3. Journal of separation science
  4. Naunyn-Schmiedeberg's archives of pharmacology
  5. The American journal of Chinese medicine
View 25 additional sources
  1. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
  2. Brazilian journal of biology = Revista brasleira de biologia
  3. Critical reviews in food science and nutrition
  4. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  5. Journal of chromatography. A
  6. Yao xue xue bao = Acta pharmaceutica Sinica
  7. Rapid communications in mass spectrometry : RCM
  8. Analytical and bioanalytical chemistry
  9. Acta clinica Croatica
  10. Lipids
  11. Journal of biomolecular structure & dynamics
  12. Journal of ethnopharmacology
  13. Acta pharmacologica Sinica
  14. Phytomedicine : international journal of phytotherapy and phytopharmacology
  15. Journal of agricultural and food chemistry
  16. Cardiovascular & hematological disorders drug targets
  17. Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
  18. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
  19. Frontiers in pharmacology
  20. Presse medicale (Paris, France : 1983)
  21. The Journal of pharmacy and pharmacology
  22. Forestry research
  23. Journal of chromatography. B, Biomedical sciences and applications
  24. Farmaco (Societa chimica italiana : 1989)
  25. Current issues in molecular biology

Ginkgolide B

  1. Dr. Duke
  2. Chinese journal of natural medicines
  3. Journal of molecular modeling
  4. Brain research
  5. Journal of AOAC International
View 23 additional sources
  1. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
  2. Journal of functional biomaterials
  3. Basic research in cardiology
  4. Journal of neurochemistry
  5. Yao xue xue bao = Acta pharmaceutica Sinica
  6. National Toxicology Program technical report series
  7. Molecules (Basel, Switzerland)
  8. Zhongguo yao li xue bao = Acta pharmacologica Sinica
  9. Neurobiology of disease
  10. European journal of pharmacology
  11. Phytochemical analysis : PCA
  12. Acta pharmacologica Sinica
  13. Journal of natural products
  14. Planta medica
  15. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  16. Molecular medicine reports
  17. Journal of pharmaceutical and biomedical analysis
  18. Anticancer research
  19. Acta pharmaceutica Sinica. B
  20. Journal of ethnopharmacology
  21. Pharmacological research
  22. The Journal of pharmacy and pharmacology
  23. Farmaco (Societa chimica italiana : 1989)

Ginkgolide A

  1. Dr. Duke
  2. Journal of molecular modeling
  3. Journal of Asian natural products research
  4. Journal of AOAC International
  5. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
View 13 additional sources
  1. National Toxicology Program technical report series
  2. Molecules (Basel, Switzerland)
  3. Neurobiology of disease
  4. European journal of pharmacology
  5. Acta pharmacologica Sinica
  6. Basic research in cardiology
  7. Journal of natural products
  8. Bioinformation
  9. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  10. Yao xue xue bao = Acta pharmaceutica Sinica
  11. Journal of ethnopharmacology
  12. The Journal of pharmacy and pharmacology
  13. Farmaco (Societa chimica italiana : 1989)

Ginkgolic acids

  1. Yao xue xue bao = Acta pharmaceutica Sinica
  2. Journal of natural products
  3. Molecules (Basel, Switzerland)
  4. The Journal of pharmacy and pharmacology
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology
View 11 additional sources
  1. Phytochemical analysis : PCA
  2. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society
  3. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  4. Natural product reports
  5. Pharmacopsychiatry
  6. Cutis
  7. The American journal of Chinese medicine
  8. Naunyn-Schmiedeberg's archives of pharmacology
  9. Journal of pharmaceutical and biomedical analysis
  10. Proteomics
  11. Journal of hazardous materials

RUTIN

  1. Dr. Duke
  2. Journal of pharmaceutical and biomedical analysis
  3. Molecules (Basel, Switzerland)
  4. Journal of chromatography. A
  5. Journal de pharmacie de Belgique
View 10 additional sources
  1. Plants (Basel, Switzerland)
  2. Biochemistry and molecular biology international
  3. Analytical and bioanalytical chemistry
  4. Phytotherapy research : PTR
  5. Phytomedicine : international journal of phytotherapy and phytopharmacology
  6. The Journal of dermatology
  7. Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
  8. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
  9. Journal of ethnopharmacology
  10. Clinica chimica acta; international journal of clinical chemistry

EGB

  1. Zhonghua yi xue za zhi
  2. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
  3. Acta pharmacologica Sinica
  4. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie
  5. Journal of Korean medical science
View 9 additional sources
  1. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  2. Zhongguo yao li xue bao = Acta pharmacologica Sinica
  3. Journal of natural medicines
  4. Clinical hemorheology and microcirculation
  5. Stroke
  6. Psychopharmacology bulletin
  7. Clinical and experimental pharmacology & physiology
  8. Biochemical pharmacology
  9. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Terpenoids

  1. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
  2. Journal of molecular modeling
  3. Evidence-based complementary and alternative medicine : eCAM
  4. Journal of neurochemistry
  5. CNS & neurological disorders drug targets
View 9 additional sources
  1. Degenerative neurological and neuromuscular disease
  2. International journal of molecular sciences
  3. Fitoterapia
  4. Phytotherapy research : PTR
  5. Chinese medicine
  6. The Journal of pharmacy and pharmacology
  7. Current pharmaceutical design
  8. Pharmacological research
  9. Journal of dietary supplements

Activities

Ginkgo biloba has 762 reported activities identified across 120 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Neuroprotective, Anticancer, Antibacterial, Hepatoprotective.

Most Reported Activities

Activity Sources Consensus
Antioxidant Dr. Duke (and other 28 sources) ★★★★★
Neuroprotective Dr. Duke (and other 19 sources) ★★★★★
Anticancer Dr. Duke (and other 8 sources) ★★★★☆
Antibacterial Dr. Duke (and other 6 sources) ★★★☆☆
Hepatoprotective Dr. Duke (and other 5 sources) ★★★☆☆
Antidementia Dr. Duke (and other 4 sources) ★★☆☆☆
Antihypertensive Dr. Duke (and other 4 sources) ★★☆☆☆
Antitumor Dr. Duke (and other 4 sources) ★★☆☆☆
Cardioprotective Dr. Duke (and other 4 sources) ★★☆☆☆
Angiogenic Dr. Duke (and other 3 sources) ★★☆☆☆

Medicinal Uses

Ginkgo biloba has 240 reported medicinal uses identified across 120 scientific publications and several other databases. The most consistently reported uses include dementia, Alzheimer's disease, cancer, cardiovascular diseases, oxidative stress.

Most Reported Uses

Use Sources Consensus
dementia Epilepsia (and other 27 sources) ★★★★★
Alzheimer's disease Plant biology (Stuttgart, Germany) (and other 26 sources) ★★★★★
cancer Natural product research (and other 13 sources) ★★★★★
cardiovascular diseases International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition (and other 13 sources) ★★★★★
oxidative stress Stroke (and other 13 sources) ★★★★★
cognitive impairment Epilepsia (and other 9 sources) ★★★★☆
memory International journal of clinical pharmacology research (and other 9 sources) ★★★★☆
tinnitus Frontiers in pharmacology (and other 9 sources) ★★★★☆
anxiety Plants (Basel, Switzerland) (and other 8 sources) ★★★★☆
cerebral ischemia Acta pharmacologica Sinica (and other 8 sources) ★★★★☆

Preparations

Preparations Sources Consensus
Ginkgo biloba extract Brain research (and other 42 sources) ★★★★★
EGb 761 Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie (and other 16 sources) ★★★★★
extract Biology of the neonate (and other 16 sources) ★★★★★
extracts Journal of pharmaceutical and biomedical analysis (and other 14 sources) ★★★★★
EGb Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie (and other 6 sources) ★★★☆☆
EGb 761® Molecular neurobiology (and other 4 sources) ★★☆☆☆
Ginkgo biloba extract (EGb 761) Life sciences (and other 4 sources) ★★☆☆☆
Ginkgo biloba extracts Stroke (and other 4 sources) ★★☆☆☆
plant extracts BioMed research international (and other 4 sources) ★★☆☆☆
Ginkgo biloba extract (EGb) Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 3 sources) ★★☆☆☆