maidenhair tree
Ginkgo biloba · Accepted scientific name
Scientific literature: Very Extensive (2603 studies) · ★★★★★
Maidenhair tree, scientifically known as Ginkgo biloba, is a living fossil with a history spanning millions of years. Renowned for its unique fan-shaped leaves, this resilient species is widely used in traditional medicine to support cognitive function, enhance memory, and improve circulation, offering profound benefits for brain health.
Names
Common Names
- Maidenhair-tree
- gingko
- golden fossil tree
- stinkbomb tree
Regional and Traditional Names
Spanish:
- Gingko
- Ginko
- Gingko biloba
- Ginko biloba
- Árbol de los cuarenta escudos
- Arbol de los cuarenta escudos
- Xinkgo
- albaricoque de plata
- árbol de doncella
- planta de ginkgo
- árbol de ginkgo
- gingko
- ginkgo
- árbol de los cuarenta escudos
- nogal del Japón
- nogal de Japón
- albaricoque plateado
German:
- Ginkgo
- Silberaprikose
- Ginkgo biloba Linne
- Fächerbaum
- Ginkgobaum
- Fächerblattbaum
- Ginkgogewächse
- Silberpflaume
- Salisburia adiantifolia
- Ginkyo
- Ginkgobaum
French:
- Gingkos
- Arbre aux 40 écus
- Arbre aux quarante écus
- Gingko biloba
- noyer du Japon
- Arbre aux quarante écus
Scientific Names
Accepted name
Ginkgo bilobaSynonyms
- Ginkgo biloba f. pendula
- Ginkgo biloba var. laciniata
- Ginkgo biloba var. pendula
- Ginkgo biloba f. fastigiata
- Ginkgo biloba f. laciniata
- Ginkgo biloba f. macrophylla
- Salisburia biloba
- Ginkgo biloba f. aurea
- Pterophyllus salisburiensis aurea
- Salisburia adiantifolia var. variegata
- Salisburia adiantifolia var. laciniata
- Ginkgo biloba var. latifolia
- Ginkgo biloba aureovariegata
- Salisburia adiantifolia var. pendula
- Salisburia macrophylla
- Ginkgo macrophylla
- Ginkgo biloba var. epiphylla
- Ginkgo biloba var. fastigiata
- Ginkgo biloba f. microsperma
- Ginkgo biloba var. variegata
- Ginkgo biloba macrophylla-laciniata
- Ginkgo biloba var. macrophylla
- Ginkgo biloba var. triloba
- Ginkgo biloba var. longifolia
- Ginkgo biloba f. adiantifolia
- Ginkgo biloba f. variegata
- Ginkgo biloba var. aurea
- Ginkgo biloba f. parvifolia
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Ginkgoidae. It is uniquely positioned within the order Ginkgoales and the family Ginkgoaceae. Ultimately, it is classified under the single-species genus Ginkgo.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Ginkgoidae | WCVP |
| Order | Ginkgoales | WCVP |
| Family | Ginkgoaceae | WCVP |
| Genus | Ginkgo | WCVP |
Distribution
This plant exhibits a wide geographical distribution that spans across several distinct regions. In Asia, its natural range includes China South-Central, China North-Central, and China Southeast. Moving toward the European continent, the species can be found in Southeastern Europe, specifically within Romania. Additionally, the plant is present in Middle Europe, notably in Austria. These diverse locations highlight the plant's ability to establish itself across various environmental zones.
| Region | Area | Source |
|---|---|---|
| Middle Europe | Austria | WCVP |
| Southeastern Europe | Romania | WCVP |
| China | China South-Central | WCVP |
| China | China North-Central | WCVP |
| China | China Southeast | WCVP |
| Eastern Asia | Japan | WCVP |
| Eastern Asia | Korea | WCVP |
| North-Central U.S.A. | Illinois | WCVP |
Plant Parts
This plant, commonly known as the maidenhair tree, offers various components used in traditional and modern medicine. Most therapeutic applications focus on the leaves, as the dried leaf is often processed into a concentrated leaf extract to support cognitive function and blood circulation. While the seeds are also edible when prepared correctly, the seed itself contains different chemical compounds than the foliage, making the leaf-based preparations the most frequent choice for medicinal supplements.| Plant Part | Sources | Consensus |
|---|---|---|
| leaf | Acta pharmacologica Sinica (and other 94 sources) | ★★★★★ |
| seed | Biochimica et biophysica acta (and other 14 sources) | ★★★★★ |
| root | Current microbiology (and other 5 sources) | ★★★☆☆ |
| fruit | Plants (Basel, Switzerland) (and other 4 sources) | ★★☆☆☆ |
| stem | Current microbiology (and other 3 sources) | ★★☆☆☆ |
Chemicals
Ginkgo biloba has 387 reported phytochemicals identified across 120 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, Bilobalide, quercetin, kaempferol, Ginkgolide B.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Flavonoids | 43 supporting sources | ★★★★★ |
| Bilobalide | 36 supporting sources | ★★★★★ |
| quercetin | 35 supporting sources | ★★★★★ |
| kaempferol | 30 supporting sources | ★★★★★ |
| Ginkgolide B | 28 supporting sources | ★★★★★ |
| Ginkgolide A | 18 supporting sources | ★★★★★ |
| Ginkgolic acids | 16 supporting sources | ★★★★★ |
| RUTIN | 15 supporting sources | ★★★★★ |
| EGB | 14 supporting sources | ★★★★★ |
| Terpenoids | 14 supporting sources | ★★★★★ |
Flavonoids
- Dr. Duke
- Tree physiology
- International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
- Plant biology (Stuttgart, Germany)
- Metabolites
View 38 additional sources
- Evidence-based complementary and alternative medicine : eCAM
- Pharmacognosy reviews
- Planta medica
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- Plants (Basel, Switzerland)
- BMC plant biology
- The American journal of Chinese medicine
- Journal of neurochemistry
- Molecules (Basel, Switzerland)
- Journal of agricultural and food chemistry
- CNS & neurological disorders drug targets
- Degenerative neurological and neuromuscular disease
- Journal of the science of food and agriculture
- Biochemistry and molecular biology international
- International journal of molecular sciences
- BioMed research international
- Lipids
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Frontiers in plant science
- Plant physiology and biochemistry : PPB
- Die Pharmazie
- Frontiers in genetics
- Journal of food science
- Gene
- Journal of separation science
- Nutrients
- Proteomics
- Chinese medicine
- The Journal of pharmacy and pharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Enzyme and microbial technology
- Recenti progressi in medicina
- Forestry research
- Current pharmaceutical design
- Current cardiology reviews
- Clinical pharmacokinetics
- Fitoterapia
- Journal of dietary supplements
Bilobalide
- Dr. Duke
- Current microbiology
- Journal of pharmaceutical and biomedical analysis
- Rapid communications in mass spectrometry : RCM
- Naunyn-Schmiedeberg's archives of pharmacology
View 31 additional sources
- International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
- Journal of molecular modeling
- Brain research
- Journal of natural products
- Journal of AOAC International
- The American journal of Chinese medicine
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
- The Journal of pharmacy and pharmacology
- Brazilian journal of biology = Revista brasleira de biologia
- Planta medica
- Journal of neurochemistry
- Physiologia plantarum
- Journal of chromatography. A
- International journal of molecular sciences
- Presse medicale (Paris, France : 1983)
- Molecules (Basel, Switzerland)
- Neurobiology of disease
- European journal of pharmacology
- Phytochemical analysis : PCA
- Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
- Antimicrobial agents and chemotherapy
- Cells
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Mutation research
- Yao xue xue bao = Acta pharmaceutica Sinica
- Annales pharmaceutiques francaises
- Journal of ethnopharmacology
- Pharmacological research
- Clinica chimica acta; international journal of clinical chemistry
- Farmaco (Societa chimica italiana : 1989)
- Journal of mass spectrometry : JMS
quercetin
- Dr. Duke
- Journal of pharmaceutical and biomedical analysis
- Journal of separation science
- Biochemical pharmacology
- Molecules (Basel, Switzerland)
View 30 additional sources
- FEBS letters
- The American journal of Chinese medicine
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
- Brazilian journal of biology = Revista brasleira de biologia
- National Toxicology Program technical report series
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of chromatography. A
- Yao xue xue bao = Acta pharmaceutica Sinica
- Journal of AOAC International
- Biochemistry and molecular biology international
- Rapid communications in mass spectrometry : RCM
- Analytical and bioanalytical chemistry
- Acta clinica Croatica
- Lipids
- Journal of agricultural and food chemistry
- Journal of ethnopharmacology
- Acta pharmacologica Sinica
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- The Journal of dermatology
- Foods (Basel, Switzerland)
- Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
- The Analyst
- Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
- Forestry research
- The Journal of pharmacy and pharmacology
- Fitoterapia
- Clinica chimica acta; international journal of clinical chemistry
- Journal of chromatography. B, Biomedical sciences and applications
- Farmaco (Societa chimica italiana : 1989)
- Current issues in molecular biology
kaempferol
- Dr. Duke
- Journal of pharmaceutical and biomedical analysis
- Journal of separation science
- Naunyn-Schmiedeberg's archives of pharmacology
- The American journal of Chinese medicine
View 25 additional sources
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
- Brazilian journal of biology = Revista brasleira de biologia
- Critical reviews in food science and nutrition
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Journal of chromatography. A
- Yao xue xue bao = Acta pharmaceutica Sinica
- Rapid communications in mass spectrometry : RCM
- Analytical and bioanalytical chemistry
- Acta clinica Croatica
- Lipids
- Journal of biomolecular structure & dynamics
- Journal of ethnopharmacology
- Acta pharmacologica Sinica
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Journal of agricultural and food chemistry
- Cardiovascular & hematological disorders drug targets
- Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
- Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
- Frontiers in pharmacology
- Presse medicale (Paris, France : 1983)
- The Journal of pharmacy and pharmacology
- Forestry research
- Journal of chromatography. B, Biomedical sciences and applications
- Farmaco (Societa chimica italiana : 1989)
- Current issues in molecular biology
Ginkgolide B
- Dr. Duke
- Chinese journal of natural medicines
- Journal of molecular modeling
- Brain research
- Journal of AOAC International
View 23 additional sources
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
- Journal of functional biomaterials
- Basic research in cardiology
- Journal of neurochemistry
- Yao xue xue bao = Acta pharmaceutica Sinica
- National Toxicology Program technical report series
- Molecules (Basel, Switzerland)
- Zhongguo yao li xue bao = Acta pharmacologica Sinica
- Neurobiology of disease
- European journal of pharmacology
- Phytochemical analysis : PCA
- Acta pharmacologica Sinica
- Journal of natural products
- Planta medica
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Molecular medicine reports
- Journal of pharmaceutical and biomedical analysis
- Anticancer research
- Acta pharmaceutica Sinica. B
- Journal of ethnopharmacology
- Pharmacological research
- The Journal of pharmacy and pharmacology
- Farmaco (Societa chimica italiana : 1989)
Ginkgolide A
- Dr. Duke
- Journal of molecular modeling
- Journal of Asian natural products research
- Journal of AOAC International
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
View 13 additional sources
- National Toxicology Program technical report series
- Molecules (Basel, Switzerland)
- Neurobiology of disease
- European journal of pharmacology
- Acta pharmacologica Sinica
- Basic research in cardiology
- Journal of natural products
- Bioinformation
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Yao xue xue bao = Acta pharmaceutica Sinica
- Journal of ethnopharmacology
- The Journal of pharmacy and pharmacology
- Farmaco (Societa chimica italiana : 1989)
Ginkgolic acids
- Yao xue xue bao = Acta pharmaceutica Sinica
- Journal of natural products
- Molecules (Basel, Switzerland)
- The Journal of pharmacy and pharmacology
- Phytomedicine : international journal of phytotherapy and phytopharmacology
View 11 additional sources
- Phytochemical analysis : PCA
- American journal of contact dermatitis : official journal of the American Contact Dermatitis Society
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Natural product reports
- Pharmacopsychiatry
- Cutis
- The American journal of Chinese medicine
- Naunyn-Schmiedeberg's archives of pharmacology
- Journal of pharmaceutical and biomedical analysis
- Proteomics
- Journal of hazardous materials
RUTIN
- Dr. Duke
- Journal of pharmaceutical and biomedical analysis
- Molecules (Basel, Switzerland)
- Journal of chromatography. A
- Journal de pharmacie de Belgique
View 10 additional sources
- Plants (Basel, Switzerland)
- Biochemistry and molecular biology international
- Analytical and bioanalytical chemistry
- Phytotherapy research : PTR
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- The Journal of dermatology
- Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
- Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
- Journal of ethnopharmacology
- Clinica chimica acta; international journal of clinical chemistry
EGB
- Zhonghua yi xue za zhi
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Acta pharmacologica Sinica
- Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie
- Journal of Korean medical science
View 9 additional sources
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- Zhongguo yao li xue bao = Acta pharmacologica Sinica
- Journal of natural medicines
- Clinical hemorheology and microcirculation
- Stroke
- Psychopharmacology bulletin
- Clinical and experimental pharmacology & physiology
- Biochemical pharmacology
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Terpenoids
- International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
- Journal of molecular modeling
- Evidence-based complementary and alternative medicine : eCAM
- Journal of neurochemistry
- CNS & neurological disorders drug targets
View 9 additional sources
- Degenerative neurological and neuromuscular disease
- International journal of molecular sciences
- Fitoterapia
- Phytotherapy research : PTR
- Chinese medicine
- The Journal of pharmacy and pharmacology
- Current pharmaceutical design
- Pharmacological research
- Journal of dietary supplements
Activities
Ginkgo biloba has 762 reported activities identified across 120 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Neuroprotective, Anticancer, Antibacterial, Hepatoprotective.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Antioxidant | Dr. Duke (and other 28 sources) | ★★★★★ |
| Neuroprotective | Dr. Duke (and other 19 sources) | ★★★★★ |
| Anticancer | Dr. Duke (and other 8 sources) | ★★★★☆ |
| Antibacterial | Dr. Duke (and other 6 sources) | ★★★☆☆ |
| Hepatoprotective | Dr. Duke (and other 5 sources) | ★★★☆☆ |
| Antidementia | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Antihypertensive | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Antitumor | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Cardioprotective | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Angiogenic | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
Medicinal Uses
Ginkgo biloba has 240 reported medicinal uses identified across 120 scientific publications and several other databases. The most consistently reported uses include dementia, Alzheimer's disease, cancer, cardiovascular diseases, oxidative stress.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| dementia | Epilepsia (and other 27 sources) | ★★★★★ |
| Alzheimer's disease | Plant biology (Stuttgart, Germany) (and other 26 sources) | ★★★★★ |
| cancer | Natural product research (and other 13 sources) | ★★★★★ |
| cardiovascular diseases | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition (and other 13 sources) | ★★★★★ |
| oxidative stress | Stroke (and other 13 sources) | ★★★★★ |
| cognitive impairment | Epilepsia (and other 9 sources) | ★★★★☆ |
| memory | International journal of clinical pharmacology research (and other 9 sources) | ★★★★☆ |
| tinnitus | Frontiers in pharmacology (and other 9 sources) | ★★★★☆ |
| anxiety | Plants (Basel, Switzerland) (and other 8 sources) | ★★★★☆ |
| cerebral ischemia | Acta pharmacologica Sinica (and other 8 sources) | ★★★★☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| Ginkgo biloba extract | Brain research (and other 42 sources) | ★★★★★ |
| EGb 761 | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie (and other 16 sources) | ★★★★★ |
| extract | Biology of the neonate (and other 16 sources) | ★★★★★ |
| extracts | Journal of pharmaceutical and biomedical analysis (and other 14 sources) | ★★★★★ |
| EGb | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie (and other 6 sources) | ★★★☆☆ |
| EGb 761® | Molecular neurobiology (and other 4 sources) | ★★☆☆☆ |
| Ginkgo biloba extract (EGb 761) | Life sciences (and other 4 sources) | ★★☆☆☆ |
| Ginkgo biloba extracts | Stroke (and other 4 sources) | ★★☆☆☆ |
| plant extracts | BioMed research international (and other 4 sources) | ★★☆☆☆ |
| Ginkgo biloba extract (EGb) | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 3 sources) | ★★☆☆☆ |