Garcinia celebica
Garcinia celebica · Accepted scientific name
Scientific literature: Very Sparse (2 studies) · ★☆☆☆☆
Garcinia celebica is a plant species that has gained scientific interest due to its significant biological potential. Research focusing on the leaf extracts of this plant has revealed a diverse profile of chemical constituents, including (+)-catechin, garcihombronane F, and various triterpenes. Through the use of aqueous and ethanolic preparations, scientists have been able to isolate specific leaf fractions for detailed study. These chemical compounds contribute to the plant's notable antimalarial and antiplasmodial activities. Consequently, the leaves of Garcinia celebica represent a promising natural resource for developing new medicinal treatments.
- Synonyms
- Garcinia Jawoera · Garcinia Sintang · 13 more
- Common names
- Not available
- Family
- Clusiaceae
- Distribution
- Not available
- Plant Parts
- Leaf
Classification
Synonyms
Garcinia celebica is a botanical species characterized by a complex web of taxonomic synonyms. Scientific literature identifies this plant under several different names, including Discostigma febrile and Garcinia basacensis. Furthermore, it has been historically categorized as Garcinia benthamii and Garcinia broewas in various studies. The species is also recognized by the synonym Garcinia cornea, highlighting the overlapping classifications found in botanical records. Understanding these relationships is essential for researchers seeking to maintain accurate nomenclature for the plant.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Garcinia celebica is a unique botanical specimen belonging to the vast kingdom Plantae. Within this expansive realm, it is specifically classified under the class Equisetopsida. This plant is further categorized into the order Malpighiales, reflecting its evolutionary lineage. It is a distinguished member of the genus Garcinia, which defines its core biological identity. Finally, it finds its place within the family Clusiaceae, rounding out its scientific profile.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malpighiales |
| Family | Clusiaceae |
| Genus | Garcinia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Garcinia celebica is a distinctive plant species primarily distributed throughout the tropical regions of Asia. Its natural range extends across the Indian Subcontinent, with a notable presence found throughout India. The species is also widely established across the Indo-China peninsula, spanning several diverse territories. Specifically, it can be found growing in the lush landscapes of Cambodia, Laos, Myanmar, and Thailand. This broad geographical footprint highlights the plant's adaptability to various tropical environments within the region.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Garcinia celebica is a self-supporting plant characterized by its distinct tree growth form. This species typically reaches a maximum height of 20 meters in many environments. However, under certain conditions, the tree can grow even larger, reaching a maximum height of 30 meters. This impressive stature allows it to establish a significant presence within its natural habitat.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Garcinia celebica, an Indonesian medicinal plant, has demonstrated significant antimalarial activity through its leaf extracts. Research indicates that the plant possesses potent antiplasmodial properties, specifically targeting the growth of chloroquine-resistant Plasmodium falciparum. The primary active compound identified in the leaves is (+)-catechin, which inhibits the parasite during both the trophozoite and schizont stages. This inhibition appears to function by inducing oxidative stress within the P. falciparum cells in a time- and dose-dependent manner. Given these findings, the therapeutic potential of this plant offers a promising avenue for developing new treatments in global malaria control programs.
Compounds
Garcinia celebica is an Indonesian medicinal plant that serves as a rich source of various bioactive chemical constituents. Research indicates that its leaves contain catechin, a compound notable for its ability to inhibit the growth of Plasmodium falciparum. Additionally, the plant contains important compounds such as clerosterol and friedeline, which contribute to its complex chemical profile. The presence of friedelin further highlights the diverse secondary metabolites found within this species. Through these various components, including garcihombronane F, the plant demonstrates significant potential for pharmacological applications.
Conditions
Garcinia celebica exhibits significant medicinal potential through its ability to treat various pathogens and conditions. The plant's bioactive compounds, such as catechin, effectively inhibit the neuraminidase (NA) enzymes of both C. perfringens and the H1N1 influenza virus. Furthermore, the leaf extract contains catechin, which inhibits the growth of Plasmodium falciparum by inducing oxidative stress. Research into the broader Garcinia genus, including related species, also suggests therapeutic activities against T. evansi and potential anti-Alzheimer's properties through cholinesterase enzyme inhibition.
Preparations
Garcinia celebica is prepared as leaves to facilitate the study of its medicinal properties. These leaves are utilized to produce leaf extract through ethanol extraction. Furthermore, the plant is prepared as leaf extract and fractions, which are separated based on polarity using n-hexane, ethyl acetate, and water. Research also indicates that Garcinia celebica is prepared as aqueous and ethanolic extracts for various screenings. Through these preparation methods, active compounds like catechin can be isolated from the plant material.
Parts used
Garcinia celebica is a medicinal plant that offers significant therapeutic potential through its leaves. Researchers have successfully isolated bioactive compounds, such as catechin, from these leaf extracts to combat various pathogens. Specifically, these leaf-derived compounds have demonstrated the ability to inhibit the growth of the malaria parasite Plasmodium falciparum by inducing oxidative stress. Furthermore, studies indicate that components found in the leaves can act as potent inhibitors of the neuraminidase enzyme, which is crucial for influenza virus proliferation. These findings highlight the importance of exploring the chemical properties of Garcinia celebica leaves for future drug development.