Garcinia calcicola
Garcinia calcicola · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Garcinia calcicola is a distinctive plant species that has recently gained attention for its potential therapeutic properties. Research focusing on this species has specifically examined the bioactive potential of its fruit. Through the use of an ethanol extract, scientists have been able to isolate key chemical constituents for further study. One of the most significant findings involves the identification of specific L-type compounds within the extract. These components demonstrate notable antiproliferative activities, suggesting a promising role in combatting abnormal cell growth.
- Synonyms
- Rheedia Calcicola
- Common names
- Not available
- Family
- Clusiaceae
- Distribution
- Australasia
- Plant Parts
- Fruit
Classification
Common Names
Garcinia calcicola is a fascinating plant species known by several different regional names. In certain areas, it is frequently referred to by the common name Litsake. Other local communities instead identify the same species as Voalaly. These varying names highlight the diverse linguistic landscape surrounding the plant's natural habitat. Understanding these relationships helps researchers better document the botanical heritage of the region.
Sources: Catalogue of Life (COL)
Synonyms
Garcinia calcicola is a unique botanical species that is frequently discussed within various scientific classifications. In many taxonomic records, this plant is also identified by its synonym, Rheedia calcicola. Understanding these naming conventions is essential for researchers attempting to track the species across different biological studies. Recognizing both names ensures that botanical data remains consistent and easily accessible to the global scientific community. This nomenclatural relationship serves as a vital link for anyone studying the plant's specific evolutionary lineage.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Garcinia calcicola is a specialized member of the kingdom Plantae that showcases the diverse complexity of the natural world. This botanical species is classified under the class Equisetopsida and belongs to the extensive order Malpighiales. Within this taxonomic framework, it is further categorized into the family Clusiaceae. It ultimately finds its specific place within the well-known genus Garcinia. Together, these relationships define the precise biological identity of this unique plant.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malpighiales |
| Family | Clusiaceae |
| Genus | Garcinia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Garcinia calcicola is a specialized plant species with a distinct and localized geographic presence. Its primary distribution spans across various regions of Africa, where it plays a unique role in its local ecosystems. Furthermore, the species can be found throughout the Western Indian Ocean, highlighting its connection to maritime environments. Madagascar also serves as a key habitat for this plant, supporting its continued existence in the wild. Understanding these specific ranges is essential for studying the ecological relationships that define this species.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Garcinia calcicola is characterized by its distinct growth form as a tree.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Garcinia calcicola, also known as Rheedia calcicola, has demonstrated significant antiproliferative activity through its unique chemical constituents. Research into the ethanol extracts of its fruits has successfully led to the isolation of two specific compounds, guttiferones K and L. These new guttiferone analogues were identified using extensive interpretation of one- and two-dimensional NMR spectroscopic data. To evaluate their biological potential, both compounds underwent rigorous testing against the A2780 human ovarian cancer cell line. These findings highlight the plant's promising role in the ongoing search for effective anti-cancer agents.
Compounds
Garcinia calcicola contains L-guttiferone K and its analogue, 16-hydroxyguttiferone K, which were isolated from the fruits of this Madagascar rainforest species. Researchers identified these specific compounds through a process of bioassay-guided fractionation using an ethanol extract. To ensure accuracy, the chemical structures of these two new analogues were established using extensive one- and two-dimensional NMR spectroscopic data. Beyond their structural identification, these guttiferones were specifically investigated for their potential medicinal properties. Testing revealed that both compounds exhibit significant antiproliferative activity against the A2780 human ovarian cancer cell line.
Conditions
Garcinia calcicola, also referred to as Rheedia calcicola, contains specific antiproliferative compounds known as guttiferones K and L. These substances were isolated from the ethanol extract of the plant's fruits through a process of bioassay-guided fractionation. Researchers utilized extensive NMR spectroscopic data to establish the precise chemical structures of these two new guttiferone analogues. Once identified, both guttiferone K and 16-hydroxyguttiferone K were tested for their medicinal potential. The study specifically evaluated their effectiveness in treating the A2780 human ovarian cancer cell line.
Preparations
Garcinia calcicola is prepared as an ethanol extract to facilitate the study of its chemical properties. This specific extraction process was utilized on the fruits of the plant to isolate various bioactive compounds. Through bioassay-guided fractionation of this ethanol extract, researchers successfully identified unique guttiferone analogues. The isolation of guttiferones K and L was made possible by this initial preparation method. Consequently, the ethanol extract serves as the foundational source for testing the plant's antiproliferative activity.
Parts used
Garcinia calcicola, also known by its synonym Rheedia calcicola, serves as a valuable source of bioactive chemical compounds. Researchers focused their study on the ethanol extract obtained specifically from the plant's fruit to identify potential medicinal properties. Through a process of bioassay-guided fractionation, they successfully isolated two unique guttiferone analogues known as guttiferones K and L. These newly discovered compounds were subjected to rigorous testing to determine their biological impact. Ultimately, the study revealed that these fruit-derived substances possess significant antiproliferative activity against human ovarian cancer cells.