10 Possible Side Effects Of Galium Aparine (Cleavers)

Galium aparine has some side effects when used improperly, such as allergic reactions, skin irritation, and increased bleeding in people with bleeding disorders.

Causes of these side effects include improper dosage, prolonged use, and interaction with other medications.

For example, people with bleeding disorders may experience life-altering consequences, such as frequent hospitalizations or limitations in physical activities due to heavy menstrual bleeding or uncontrollable bleeding from minor cuts.

This article explains in details the 10 most common side effects of Galium aparine if used imporperly.

1. Leads to kidney damage

Galium aparine causes allergic reactions in some individuals due to its histamine-releasing properties.

The plant's sap, leaves, and stems contain allergenic compounds that can trigger an immune response, leading to symptoms such as hives, itching, and swelling. Additionally, the presence of galactose and glucose in the plant may also contribute to allergic reactions.

As a result, people who are sensitive to these compounds may experience an adverse reaction when exposed to Galium aparine.

2. Leads to kidney damage

Galium aparine induces digestive issues when used.

The herb is believed to stimulate digestion and relieve symptoms of indigestion, but excessive consumption or individual sensitivity can cause an increase in bowel movements, diarrhea, and stomach cramps.

This is thought to be due to the high concentration of mucilage in the plant, which can irritate the digestive system and alter normal gut function.

3. Leads to kidney damage

Galium aparine increases risk of bleeding when used due to its ability to interfere with platelet function and clotting mechanisms.

The herb's compound gallic acid has been shown to inhibit platelet aggregation, leading to a reduced ability to form blood clots and increase the risk of bruising and bleeding.

Additionally, Galium aparine may also interact with anticoagulant medications, further exacerbating this side effect.

4. Leads to kidney damage

Galium aparine provokes respiratory problems when ingested due to its ability to stimulate the release of histamine in the body.

This can cause symptoms such as coughing, wheezing, and shortness of breath.

Additionally, Galium aparine's alkaloids may irritate the mucous membranes of the throat and lungs, exacerbating existing respiratory issues like asthma or bronchitis.

5. Leads to kidney damage

Galium aparine triggers cardiac arrhythmia due to its ability to slow down heart rate and decrease blood pressure.

The compound galactarin in Galium aparine is believed to be responsible for this effect, as it can interfere with the normal functioning of the cardiovascular system by altering the heart's rhythm and electrical activity.

This may lead to irregular heartbeat, palpitations, or other arrhythmia-related symptoms.

6. Leads to kidney damage

Galium aparine develops urinary tract infections.

This occurs because the herb can irritate the urinary tract and cause bacteria to multiply more easily, leading to infection.

The high water content in cleavers may also increase urine production, potentially washing away beneficial bacteria that help maintain a healthy urinary tract balance, further increasing the risk of infection.

7. Leads to kidney damage

Galium aparine increases blood pressure due to its ability to stimulate the sympathetic nervous system and cause vasoconstriction.

This is attributed to the presence of alkaloids such as gallic acid and tartaric acid in the plant, which can activate alpha-adrenergic receptors and increase cardiac output.

Additionally, Galium aparine's effect on blood vessels may also contribute to its hypertensive properties, leading to increased systolic pressure and potentially serious cardiovascular complications.

8. Leads to kidney damage

Galium aparine disrupts menstrual cycles due to its estrogenic and anti-estrogenic properties.

It has been found to interact with hormonal receptors in the body, which can lead to changes in menstruation patterns.

The plant's ability to alter hormone levels and bind to receptors can cause irregularities in the menstrual cycle, resulting in delayed or absent periods, heavy bleeding, or other symptoms of hormonal imbalance.

9. Leads to kidney damage

Galium aparine creates skin rashes due to its saponin content, which can cause allergic reactions and irritation.

The plant's sap can also bind to skin proteins, triggering an immune response that leads to the formation of red, itchy blisters or hives.

As a result, individuals using Galium aparine may experience uncomfortable and unsightly skin rashes, potentially affecting their daily activities and overall well-being.

10. Leads to kidney damage

Galium aparine stimulates anxiety attacks due to its ability to affect the brain's neurotransmitter balance.

The herb is believed to increase levels of serotonin and dopamine, which can lead to feelings of unease, nervousness, and panic when taken in excessive amounts. Additionally, Galium aparine may interact with other substances that regulate mood, such as benzodiazepines, further exacerbating anxiety symptoms.

This can result in episodes of intense fear or apprehension, making it essential for individuals to be aware of this potential side effect.