asafoetida
Ferula assa-foetida · Accepted scientific name
Scientific literature: Very Extensive (399 studies) · ★★★★★
Asafoetida, scientifically known as Ferula assa-foeida, is a pungent resin derived from the roots of perennial plants in the Apiaceae family. Renowned in Ayurvedic and traditional medicine, it possesses potent antimicrobial, anti-inflammatory, and digestive properties. This aromatic substance serves as both a culinary staple and a therapeutic agent.
Names
Common Names
- asafetida
- asafoetida
- assa-foetida
- devil's-dung
Regional and Traditional Names
Spanish:
- Ferula assafoetida
- Férula assafoétida
- Asa fetida
- Assafoetida
- Ferula assafoétida
- Assafetida
- Ferula hooshee
- Ferula assafetida
- Hing
- Asa fétida
- Asafoetida
- Asafétida
- Férula assafoetida
- Asafetida
- Peucedanum hooshe
- Asafoétida
- asafétida
German:
- Asant
- Asafoetida
- Teufelsdreck
- Asa foetida
- Stinkasant
- Hing
- Stinkasant
French:
- Ferula hooshee
- Narthex asafoetida
- Narthex polakii
- Narthex silphium
- Peucedanum asa-foetida
- Peucedanum assa-foetida
- Peucedanum hooshe
- Peucedanum hooshee
- Scorodosma assa-foetida
- férule persique
Scientific Names
Accepted name
Ferula assa-foetidaSynonyms
- Peucedanum hooshee
- Scorodosma assa-foetida
- Peucedanum assa-foetida
- Ferula foetida
- Ferula hooshee
- Narthex silphium
- Narthex polakii
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Apiales, it is classified under the family Apiaceae. Specifically, its taxonomic identity is defined by the genus Ferula, of which Ferula assa-foetida is a notable species.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Apiales | WCVP |
| Family | Apiaceae | WCVP |
| Genus | Ferula | WCVP |
Distribution
This plant exhibits a widespread geographical distribution across several key regions of the continent. In Northern Africa, its presence is specifically noted within the borders of Libya. Moving into Central Asia, the species can be found throughout Kazakhstan, Turkmenistan, and Uzbekistan. Additionally, the plant is established within Western Asia, particularly in the country of Iran. Together, these locations highlight its ability to thrive across diverse territories in the Old World.
| Region | Area | Source |
|---|---|---|
| Northern Africa | Libya | WCVP |
| Central Asia | Kazakhstan | WCVP |
| Central Asia | Turkmenistan | WCVP |
| Central Asia | Uzbekistan | WCVP |
| Western Asia | Iran | WCVP |
| Indian Subcontinent | Bangladesh | WCVP |
| Indo-China | Laos | WCVP |
Plant Parts
This plant, Ferula assa-foeida, is a perennial herb highly valued for its complex chemical constituents harvested from various subterranean structures. The medicinal properties are primarily derived from the oleo-gum-resin that exudes from the plant's internal tissues. This substance, often referred to simply as oleo-gum, is collected from the roots and the thick, fleshy rhizome. Depending on the specific method of extraction and the maturity of the plant, the harvested oleo-gum-resin serves as the essential source for traditional and pharmacological applications.| Plant Part | Sources | Consensus |
|---|---|---|
| root | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| rhizome | International journal of nanomedicine (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Ferula assa-foetida has 96 reported phytochemicals identified across 3 scientific publications and several other databases. The most consistently reported chemicals include Farnesiferol C, Galbanic acid, 8-acetoxy-5-hydroxyumbelliprenin, Coumarins, Farnesiferol B.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Farnesiferol C | 4 supporting sources | ★★☆☆☆ |
| Galbanic acid | 4 supporting sources | ★★☆☆☆ |
| 8-acetoxy-5-hydroxyumbelliprenin | 2 supporting sources | ★☆☆☆☆ |
| Coumarins | 2 supporting sources | ★☆☆☆☆ |
| Farnesiferol B | 2 supporting sources | ★☆☆☆☆ |
| Karatavicinol | 2 supporting sources | ★☆☆☆☆ |
| Umbelliprenin | 2 supporting sources | ★☆☆☆☆ |
| arginine | 2 supporting sources | ★☆☆☆☆ |
| ferulic acid | 2 supporting sources | ★☆☆☆☆ |
| 1-methylpropyl 1-propenyl disulfide | 1 supporting sources | ★☆☆☆☆ |
Farnesiferol C
- Dr. Duke
- Journal of Asian natural products research
- Journal of ethnopharmacology
- Fitoterapia
Galbanic acid
- Dr. Duke
- Journal of photochemistry and photobiology. B, Biology
- Biological & pharmaceutical bulletin
- Fitoterapia
8-acetoxy-5-hydroxyumbelliprenin
- Dr. Duke
- Journal of natural products
Coumarins
- Letters in applied microbiology
- Current diabetes reviews
Farnesiferol B
- Dr. Duke
- Fitoterapia
Karatavicinol
- Dr. Duke
- Journal of ethnopharmacology
Umbelliprenin
- Dr. Duke
- Fitoterapia
arginine
- Food research international (Ottawa, Ont.)
- Journal of proteomics
ferulic acid
- Dr. Duke
- Combinatorial chemistry & high throughput screening
1-methylpropyl 1-propenyl disulfide
- Dr. Duke
Activities
Ferula assa-foetida has 233 reported activities identified across 3 scientific publications and several other databases. The most consistently reported activities include Cytotoxic, Antimicrobial, Antiviral, Apoptotic, Antimutagenic.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Cytotoxic | Dr. Duke (and other 5 sources) | ★★★☆☆ |
| Antimicrobial | Pharmaceutical biology (and other 4 sources) | ★★☆☆☆ |
| Antiviral | Dr. Duke (and other 4 sources) | ★★☆☆☆ |
| Apoptotic | Dr. Duke (and other 3 sources) | ★★☆☆☆ |
| Antimutagenic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antiproliferative | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antispasmodic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Antitumor | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| Diuretic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| 5-Alpha-Reductase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Ferula assa-foetida has 12 reported medicinal uses identified across 3 scientific publications and several other databases. The most consistently reported uses include asthma, gastrointestinal disorders, Breast Cancer, Candida albicans, HCT-116 cells.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| asthma | Journal of complementary & integrative medicine (and other 3 sources) | ★★☆☆☆ |
| gastrointestinal disorders | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| Breast Cancer | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology (and other 1 sources) | ★☆☆☆☆ |
| Candida albicans | Fitoterapia (and other 1 sources) | ★☆☆☆☆ |
| HCT-116 cells | Combinatorial chemistry & high throughput screening (and other 1 sources) | ★☆☆☆☆ |
| Parkinson's disease | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| breast cancer | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology (and other 1 sources) | ★☆☆☆☆ |
| cancer | World journal of biological chemistry (and other 1 sources) | ★☆☆☆☆ |
| constipation | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| diuretic | Indian journal of nephrology (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| oleo-gum-resin | Journal of ethnopharmacology (and other 2 sources) | ★☆☆☆☆ |
| CHCl(3)-soluble extract | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| Essential Oil | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology (and other 1 sources) | ★☆☆☆☆ |
| Oleo-Gum-Resin | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology (and other 1 sources) | ★☆☆☆☆ |
| Oleo-gum-resin extract | Combinatorial chemistry & high throughput screening (and other 1 sources) | ★☆☆☆☆ |
| aqueous extract | International journal of nanomedicine (and other 1 sources) | ★☆☆☆☆ |
| asafoetida gum | International journal of nanomedicine (and other 1 sources) | ★☆☆☆☆ |
| derived compounds | World journal of biological chemistry (and other 1 sources) | ★☆☆☆☆ |
| essential oil | Fitoterapia (and other 1 sources) | ★☆☆☆☆ |
| essential oils | World journal of biological chemistry (and other 1 sources) | ★☆☆☆☆ |