longjack

Eurycoma longifolia · Accepted scientific name

Scientific literature: Very Extensive (228 studies) · ★★★★★

Longjack, scientifically known as Eurycoma longifolia, is a powerful medicinal plant native to Southeast Asia. Renowned for its potent bioactive compounds, it is widely utilized in traditional medicine to enhance vitality, support hormonal balance, and boost energy levels. This versatile herb remains a cornerstone of natural wellness supplements globally.

Family
Simaroubaceae
Native range
Asia-Tropical
Parts used
Root · Stem
Common names
Not available
Scientific synonyms
Not available

Names and Synonyms

Scientific Names

Accepted name

Eurycoma longifolia

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant, Eurycoma longifolia, belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within the class Equisetopsida and subclass Magnoliidae, it is organized under the order Sapindaales and the family Simaroubaceae. Ultimately, its taxonomic placement is defined by its membership in the genus Eurycoma.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Sapindales
Family Simaroubaceae
Genus Eurycoma

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, known scientifically as Eurycoma longifolia, exhibits a specific geographical distribution across the Indo-China region. It is natively found within the tropical landscapes of Cambodia and Laos. Furthermore, its natural habitat extends into the territories of Myanmar and Thailand. The species also thrives throughout various parts of Vietnam. Consequently, its presence is well-established across these five distinct Southeast Asian nations.

Region Area
Indo-China Cambodia
Indo-China Laos
Indo-China Myanmar
Indo-China Thailand
Indo-China Vietnam
Malesia Borneo
Malesia Malaya
Malesia Philippines
Malesia Sumatera

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Eurycoma longifolia is characterized by a perennial lifecycle, allowing the plant to persist in its natural habitat over many years. As a phanerophyte, its reproductive buds are located high above the ground on woody stems, a growth form that enables it to compete effectively within its ecosystem. This phanerophyte classification is consistent across its developmental stages, as it maintains its structural integrity through robust, elevated branching patterns that define its long-term presence in the forest landscape.

Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Eurycoma longifolia is characterized by a woody growth form, specifically manifesting as a tree. This species typically reaches an average height of approximately 8 m. Regarding its growth habit and structural support, it is classified as a self-supporting plant rather than a climbing liana or vine. Furthermore, it is a terrestrial species, lacking the characteristics of an epiphyte.

Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
tree
Plant height mean:
8 m
Woodiness :
woody

Physiology

The physiology of Eurycoma longifolia is characterized by a metabolic framework utilizing the C3 photosynthetic pathway, which dictates its carbon fixation processes and gas exchange mechanisms. As a C3 plant, it relies on the direct fixation of atmospheric carbon dioxide through the enzyme Rubisco during the Calvin cycle, a process that typically occurs under moderate environmental conditions. Furthermore, this species does not function as a nitrogen fixer, meaning it lacks the symbiotic relationship with diazotrophic bacteria required to convert atmospheric nitrogen into bioavailable forms, instead relying on the uptake of nitrogenous compounds directly from the soil substrate.

Nitrogen fixer :
no
Photosynthetic pathway :
C3

Reproduction

The reproduction of Eurycoma longifolia is primarily driven by sexual processes facilitated by its flowering structure, though the mechanism of genetic exchange is strictly regulated. In terms of its mating system, self-fertilization is notably absent, indicating that the species relies on cross-pollination to maintain genetic diversity and avoid inbreeding depression. This absence of self-fertilization suggests that the plant requires external agents, such as insects or wind, to transfer pollen between different individual plants. The reproductive cycle involves the development of flowers that must undergo exogenous pollination to successfully produce seeds, ensuring a robust genetic recombination within the population.

Self fertilization :
absent

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Eurycoma longifolia has 3 reported plant parts identified across 19 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, stem, leaf.

Plant parts reported in Eurycoma longifolia
Plant part Supporting sources Consensus
Root 14 supporting sources ★★★★★
Stem 3 supporting sources ★★☆☆☆
Leaf 2 supporting sources ★☆☆☆☆

Root

  1. Bioorganic & medicinal chemistry letters
  2. Journal of nutritional science and vitaminology
  3. Journal of the International Society of Sports Nutrition
  4. Pakistan journal of biological sciences : PJBS
  5. Molecules (Basel, Switzerland)
View 9 additional sources
  1. Natural product research
  2. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
  3. Current drug targets
  4. Microvascular research
  5. Scientific reports
  6. Journal of natural products
  7. Chemistry & biodiversity
  8. Drug testing and analysis
  9. Tropical biomedicine

Stem

  1. Journal of natural products
  2. Frontiers in pharmacology
  3. Current drug targets

Leaf

  1. Current drug targets
  2. Journal of ethnopharmacology

Chemicals

Eurycoma longifolia has 26 reported phytochemicals identified across 19 scientific publications and several other databases. The most consistently reported chemicals include Eurycomanone, 9-Hydroxycanthin-6-one, 9-Methoxycanthin-6-one, Eurycomalactone, Eurycomanol.

Chemicals reported in Eurycoma longifolia
Chemical Supporting sources Consensus
Eurycomanone 7 supporting sources ★★★★☆
9-Hydroxycanthin-6-one 4 supporting sources ★★☆☆☆
9-Methoxycanthin-6-one 4 supporting sources ★★☆☆☆
Eurycomalactone 4 supporting sources ★★☆☆☆
Eurycomanol 3 supporting sources ★★☆☆☆
Cortisol 2 supporting sources ★☆☆☆☆
Eurycomalide C 2 supporting sources ★☆☆☆☆
longilactone 2 supporting sources ★☆☆☆☆
11-dehydroklaineanone 1 supporting sources ★☆☆☆☆
14,15beta-dihydroxyklaineanone 1 supporting sources ★☆☆☆☆

Eurycomanone

  1. Phytomedicine : international journal of phytotherapy and phytopharmacology
  2. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
  3. Planta medica
  4. Heliyon
  5. Pharmaceutical biology
View 2 additional sources
  1. Current drug targets
  2. Microvascular research

9-Hydroxycanthin-6-one

  1. Natural product research
  2. Scientific reports
  3. Chemistry & biodiversity
  4. Drug testing and analysis

9-Methoxycanthin-6-one

  1. Natural product research
  2. Scientific reports
  3. Chemistry & biodiversity
  4. Drug testing and analysis

Eurycomalactone

  1. Heliyon
  2. Molecules (Basel, Switzerland)
  3. Journal of natural products
  4. Drug testing and analysis

Eurycomanol

  1. Frontiers in pharmacology
  2. Microvascular research
  3. Planta medica

Cortisol

  1. Journal of the International Society of Sports Nutrition
  2. Phytotherapy research : PTR

Eurycomalide C

  1. Journal of natural products
  2. Drug testing and analysis

longilactone

  1. Journal of ethnopharmacology
  2. Drug testing and analysis

11-dehydroklaineanone

  1. Journal of ethnopharmacology

14,15beta-dihydroxyklaineanone

  1. Journal of ethnopharmacology

Activities

Eurycoma longifolia has 20 reported activities identified across 19 scientific publications and several other databases. The most consistently reported activities include Aphrodisiac, Anticancer, Antimalarial, Antimicrobial, Antioxidant.

Activities reported in Eurycoma longifolia
Activity Supporting sources Consensus
Aphrodisiac 7 supporting sources ★★★★☆
Anticancer 6 supporting sources ★★★☆☆
Antimalarial 6 supporting sources ★★★☆☆
Antimicrobial 4 supporting sources ★★☆☆☆
Antioxidant 4 supporting sources ★★☆☆☆
Cytotoxic 4 supporting sources ★★☆☆☆
Antibacterial 2 supporting sources ★☆☆☆☆
Antidiabetic 2 supporting sources ★☆☆☆☆
Antifungal 2 supporting sources ★☆☆☆☆
Antiproliferative 2 supporting sources ★☆☆☆☆

Aphrodisiac

  1. Experimental animals
  2. Archives of pharmacal research
  3. Phytotherapy research : PTR
  4. Pharmaceutical biology
  5. Current drug targets
View 2 additional sources
  1. Fitoterapia
  2. Molecules (Basel, Switzerland)

Anticancer

  1. Pakistan journal of biological sciences : PJBS
  2. Pharmaceutical biology
  3. Frontiers in pharmacology
  4. The Journal of pharmacy and pharmacology
  5. Current drug targets
View 1 additional sources
  1. Current pharmaceutical biotechnology

Antimalarial

  1. Pharmaceutical biology
  2. The Journal of pharmacy and pharmacology
  3. Current drug targets
  4. Fitoterapia
  5. Current pharmaceutical biotechnology
View 1 additional sources
  1. Journal of natural products

Antimicrobial

  1. Progress in the chemistry of organic natural products
  2. Current drug targets
  3. Fitoterapia
  4. Scientific reports

Antioxidant

  1. Progress in the chemistry of organic natural products
  2. Pakistan journal of biological sciences : PJBS
  3. The Journal of pharmacy and pharmacology
  4. Current drug targets

Cytotoxic

  1. Progress in the chemistry of organic natural products
  2. Pakistan journal of biological sciences : PJBS
  3. Tropical biomedicine
  4. Journal of natural products

Antibacterial

  1. The Journal of pharmacy and pharmacology
  2. Current drug targets

Antidiabetic

  1. Pharmaceutical biology
  2. Frontiers in pharmacology

Antifungal

  1. The Journal of pharmacy and pharmacology
  2. Current drug targets

Antiproliferative

  1. Pakistan journal of biological sciences : PJBS
  2. Current drug targets

Medicinal Uses

Eurycoma longifolia has 64 reported medicinal uses identified across 19 scientific publications and several other databases. The most consistently reported uses include fever, malaria, cancer, anxiety, aphrodisiac.

Most Reported Uses

Use Sources Consensus
fever Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society (and other 7 sources) ★★★★☆
malaria Pharmaceutical biology (and other 6 sources) ★★★☆☆
cancer Pakistan journal of biological sciences : PJBS (and other 5 sources) ★★★☆☆
anxiety Japanese journal of pharmacology (and other 3 sources) ★★☆☆☆
aphrodisiac Biological & pharmaceutical bulletin (and other 3 sources) ★★☆☆☆
hypertension Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society (and other 3 sources) ★★☆☆☆
libido Journal of the International Society of Sports Nutrition (and other 3 sources) ★★☆☆☆
Plasmodium falciparum Planta medica (and other 2 sources) ★☆☆☆☆
aches Journal of nutritional science and vitaminology (and other 2 sources) ★☆☆☆☆
antimalarial The Journal of pharmacy and pharmacology (and other 2 sources) ★☆☆☆☆

Preparations

Preparations Sources Consensus
CitruSlim Phytotherapy research : PTR (and other 1 sources) ★☆☆☆☆
EL extract Evidence-based complementary and alternative medicine : eCAM (and other 1 sources) ★☆☆☆☆
Eurycoma longifolia root extract Drug testing and analysis (and other 1 sources) ★☆☆☆☆
Methanol and ethyl acetate extraction Pakistan journal of biological sciences : PJBS (and other 1 sources) ★☆☆☆☆
Radix Pakistan journal of biological sciences : PJBS (and other 1 sources) ★☆☆☆☆
Roots Molecules (Basel, Switzerland) (and other 1 sources) ★☆☆☆☆
aqueous extracts Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
crude extracts from the roots Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (and other 1 sources) ★☆☆☆☆
extract of E. longifolia Journal of natural products (and other 1 sources) ★☆☆☆☆
hairy root culture Scientific reports (and other 1 sources) ★☆☆☆☆