By Leen Randell
Updated: Oct 21, 2024
What to know about Eurycoma longifolia before using it medicinally
Eurycoma longifolia, commonly known as tongkat ali, is a medicinal herb used to treat various health conditions, including fatigue, low libido, and erectile dysfunction.
The main health benefits of Eurycoma longifolia include its ability to improve physical performance, enhance mental clarity, and support immune function. Its therapeutic properties include anti-inflammatory, antioxidant, and adaptogenic effects, which contribute to its potential to reduce stress and anxiety. The bioactive compounds responsible for these effects include flavonoids, phenolic acids, and alkaloids, particularly eurycomanone and eurycomanol.
People often prepare Eurycoma longifolia as a standardized extract or tea, which can be used to support overall well-being and address specific health concerns.
Featured Study:
According to a study published by "Experimental animals", the administration of Eurycoma longifolia in castrated male rats resulted in a significant increase in their sexual performance, with the effect being dose-dependent. Additionally, Eurycoma longifolia promoted the growth of both the ventral prostate and seminal vesicles, indicating its potential to enhance male reproductive health. Furthermore, this study provides evidence to support the traditional use of Eurycoma longifolia as an aphrodisiac, suggesting its possible benefits for male fertility and sexual function.
The following article explains in detail what are the medicinal uses of Eurycoma longifolia, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.
ARTICLE SUMMARY: The table below summarizes the most crucial information about Eurycoma longifolia provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.
| Medicinal Aspect | Summary |
|---|---|
| Uses | Fatigue, Diabetes, Impotence, Anxiety, Depression, Erectile dysfunction, Inflammation, Hypertension, Osteoporosis, Arthritis |
| Benefits | Increases testosterone, Reduces body fat, Improves mental clarity, Boosts immune system, Enhances physical performance, Reduces inflammation levels, Lowers stress hormones, Improves sleep quality, Increases energy levels, Supports anti-aging process |
| Properties | Antioxidant, Antimicrobial, Anti-inflammatory, Analgesic, Antioxidative, Antidiabetic, Neuroprotective, Immunomodulatory, Anticancer, Anti-androgenic |
| Constituents | Flavonoids, Saponins, Phenolic acids, Alkaloids, Terpenoids, Glycosides, Quassinoids, Coumarins, Triterpenoids, Sterols |
| Parts | Roots, Leaves |
| Preparations | Tincture, Capsule, Oil, Tea, Salve |
| Side Effects | Experiencing nausea, Showing abdominal pain, Experiencing diarrhea, Developing dizziness, Experiencing headache, Showing fatigue, Experiencing insomnia, Developing anxiety, Experiencing depression, Interacting with other medications |
| Precaution | Consult a doctor before use, Follow recommended dosage, Monitor blood pressure, Be aware of interactions with medications, Avoid use during pregnancy, Avoid use with antidepressants, Be cautious with thyroid medications, Monitor liver function, Be aware of allergic reactions, Stop use if side effects occur |
BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Eurycoma longifolia. Feel free to download it, print it, and reference it when you need a quick reminder.
- What are the main medicinal uses of Eurycoma longifolia?
- Modern Western Medicine
- Traditional Chinese Medicine
- Ayurvedic Medicine
- Unani Medicine
- Homeopathic Medicine
- What are the primary health benefits of Eurycoma longifolia?
- Circulatory System
- Digestive System
- Endocrine System
- Integumentary System
- Lymphatic System
- Musculoskeletal System
- Nervous System
- Reproductive System
- Respiratory System
- Urinary System
- What are the dominant therapeutic properties of Eurycoma longifolia?
- What are the major healing constituents of Eurycoma longifolia?
- What are the most used parts of Eurycoma longifolia in medicine?
- What are the most common medicinal preparations of Eurycoma longifolia?
- What are the possible side effects of Eurycoma longifolia if used improperly?
- What are the precautions to take before using Eurycoma longifolia medicinally?
- Are there scientific studies that prove the medical effectiveness of Eurycoma longifolia?
- Related herbs to Eurycoma longifolia?
What are the main medicinal uses of Eurycoma longifolia?
The main medicinal uses of Eurycoma longifolia are its ability to alleviate fatigue by increasing testosterone levels due to its high content of eurycomanone, a compound that stimulates the hypothalamic-pituitary-gonadal axis.
It also has anxiolytic properties, reducing anxiety by modulating the GABA receptor system, and its bioactive compounds, such as ursolic acid, contribute to the relief of erectile dysfunction by enhancing nitric oxide production. Eurycoma longifolia's anti-inflammatory properties, attributed to its flavonoids and alkaloids, help alleviate depression by reducing inflammation in the brain. Additionally, the plant's ability to suppress appetite and increase metabolism, due to its high content of flavonoids and phenolic acids, facilitates weight loss.
Furthermore, eurycomanone and other bioactive compounds in Eurycoma longifolia have been shown to inhibit cancer cell proliferation and induce apoptosis, making it a potential adjunctive treatment for diabetes and low libido.
The following illustration give a summary of the main medicinal uses of Eurycoma longifolia.
The list below provide more details on why Eurycoma longifolia is used to alleviate the health conditions mentioned in the illustration above.
- Fatigue: This plant is used for fatigue due to its adaptogenic properties, which help the body to resist stress and promote balance in the body's physiological processes, thereby reducing feelings of tiredness and fatigue.
- Diabetes: It is used to manage diabetes due to its potential to lower blood sugar levels and improve insulin sensitivity, possibly through its ability to inhibit the activity of enzymes involved in glucose production and enhance the activity of enzymes involved in glucose uptake.
- Impotence: This plant is used to treat impotence due to its potential to enhance libido and improve erectile function, possibly through its ability to increase testosterone levels and improve nitric oxide production, which can enhance blood flow to the penis.
- Anxiety: It is used to manage anxiety due to its adaptogenic properties, which help the body to resist stress and promote balance in the body's physiological processes, thereby reducing feelings of anxiety and stress.
- Depression: This plant is used to treat depression due to its potential to enhance mood and reduce symptoms of depression, possibly through its ability to increase serotonin and dopamine levels, which can improve mood and reduce symptoms of depression.
- Erectile Dysfunction: It is used to treat erectile dysfunction due to its potential to enhance libido and improve erectile function, possibly through its ability to increase testosterone levels and improve nitric oxide production, which can enhance blood flow to the penis.
- Inflammation: This plant is used to manage inflammation due to its potential anti-inflammatory properties, which can reduce inflammation and pain associated with various inflammatory conditions.
- Hypertension: It is used to manage hypertension due to its potential to lower blood pressure, possibly through its ability to inhibit the activity of enzymes involved in blood pressure regulation and enhance the activity of enzymes involved in blood pressure reduction.
- Osteoporosis: This plant is used to treat osteoporosis due to its potential to enhance bone density and reduce the risk of bone fractures, possibly through its ability to increase bone formation and reduce bone resorption.
- Arthritis: It is used to manage arthritis due to its potential anti-inflammatory and analgesic properties, which can reduce pain and inflammation associated with various arthritic conditions.
The table that follows gives an overview of what are the most common health conditions that are treated with Eurycoma longifolia, in each of the major medicinal systems.
| Medicinal System | Conditions Treated |
|---|---|
| Modern Western Medicine | Fatigue, Erectile Dysfunction, Depression, Anxiety, Diabetes, Cancer Prevention, Inflammation, Hypertension, Weight Loss, Osteoporosis, Impotence, Obesity, Arthritis, Sleep Disorders, Hypogonadism, Male Infertility, Stress, Prostate Enlargement, Malaria, Low Testosterone |
| Traditional Chinese Medicine | Fatigue, Impotence, Anxiety, Diabetes, Depression, Inflammation, Cancer, Arthritis, Erectile Dysfunction, Hypertension, Weight Loss, Hiv, Osteoporosis, Obesity, Insomnia, Low Testosterone, Hair Loss, Aging, Male Pattern Baldness, Chronic Pain |
| Ayurvedic Medicine | Fatigue, Diabetes, Anxiety, Depression, Impotence, Hypertension, Erectile Dysfunction, Obesity, Osteoporosis, Inflammation, Sleep Disorder, Cancer, Weight Loss, Arthritis, Low Libido, Infertility, Hypogonadism, Low Testosterone, High Blood Pressure, Asthma |
| Unani Medicine | Impotence, Diabetes, Fatigue, Erectile Dysfunction, Anxiety, Depression, Cancer, Hypertension, Osteoporosis, Inflammation, Arthritis, Obesity, Infertility, Hiv, Weight Loss, Malaria, Stress, Rheumatism, Fever, Sleep Disorders |
| Homeopathic Medicine | Fatigue, Anxiety, Depression, Diabetes, Impotence, Erectile Dysfunction, Inflammation, Weight Loss, Osteoporosis, Cancer, Arthritis, Obesity, Hypertension, Insomnia, Low Testosterone, Male Infertility, Sleep Disorder, Hiv, Hypogonadism, Low Libido |
Modern Western Medicine
In modern western medicine, Eurycoma longifolia is used to treat fatigue by increasing energy levels and endurance.
The plant is also effective in addressing erectile dysfunction through its ability to enhance testosterone production and improve blood flow. Additionally, research has shown that Eurycoma longifolia has antidepressant properties, reducing symptoms of depression by regulating neurotransmitter levels. Furthermore, it has been studied for its potential to alleviate anxiety, inflammation, diabetes, cancer prevention, hypertension, weight loss, osteoporosis, impotence, and obesity.
The plant is also being investigated for its benefits in treating arthritis, sleep disorders, hypogonadism, male infertility, stress, prostate enlargement, malaria, and low testosterone.
Traditional Chinese Medicine
In traditional chinese medicine, Eurycoma longifolia is used to treat a variety of health conditions, including fatigue, where it helps to boost energy levels and alleviate exhaustion.
It is also used to treat impotence, as it has been shown to increase testosterone levels and improve sexual function. Moreover, Eurycoma longifolia is used to treat anxiety, by reducing stress and promoting relaxation. Additionally, it is used to treat diabetes, depression, inflammation, cancer, arthritis, erectile dysfunction, hypertension, weight loss, HIV, osteoporosis, obesity, insomnia, low testosterone, hair loss, and aging, as well as male pattern baldness and chronic pain, due to its anti-inflammatory, antioxidant, and anti-cancer properties.
By promoting overall well-being and reducing symptoms of various health conditions, Eurycoma longifolia has become a valuable herb in traditional chinese medicine.
Ayurvedic Medicine
In ayurvedic medicine, Eurycoma longifolia is used to alleviate fatigue, which often leads to reduced productivity.
The plant's extracts have been studied for their potential to manage diabetes, particularly type 2, by regulating blood sugar levels and improving insulin sensitivity. Additionally, Eurycoma longifolia has been shown to have anxiolytic properties, reducing anxiety and stress levels in individuals. Its adaptogenic properties also help alleviate symptoms of depression and impotence, while its antioxidant and vasodilatory properties may help lower hypertension and erectile dysfunction.
Furthermore, the plant has been traditionally used to treat a range of conditions, including obesity, osteoporosis, inflammation, sleep disorder, cancer, weight loss, arthritis, low libido, infertility, hypogonadism, low testosterone, high blood pressure, and asthma, making it a valuable adjunct to conventional treatments.
Unani Medicine
In unani medicine, Eurycoma longifolia is used to treat impotence, a condition characterized by the inability to achieve or maintain an erection, due to its ability to increase testosterone levels and improve sexual function.
It is also used to manage diabetes, a metabolic disorder that affects blood sugar regulation, by reducing oxidative stress and improving insulin sensitivity. Additionally, Eurycoma longifolia is employed to alleviate fatigue, a state of physical, mental, or emotional exhaustion, by enhancing energy levels and reducing inflammation. Furthermore, it is utilized to address erectile dysfunction, anxiety, depression, cancer, hypertension, osteoporosis, inflammation, arthritis, obesity, infertility, HIV, weight loss, malaria, stress, rheumatism, fever, and sleep disorders, making it a versatile medicinal plant in unani medicine.
The bioactive compounds present in Eurycoma longifolia, such as eurycomanone and eurycomalactone, are responsible for its medicinal properties and are being studied extensively for their potential therapeutic benefits.
Homeopathic Medicine
In homeopathic medicine, Eurycoma longifolia is used to treat various health conditions, including fatigue, which is often associated with low energy levels, as well as anxiety, a common mental health disorder characterized by excessive worry.
Additionally, Eurycoma longifolia has been used to alleviate symptoms of depression, a mood disorder that affects millions worldwide, while also providing benefits for individuals with diabetes, a chronic condition that requires careful management of blood sugar levels. The plant has also been used to address male reproductive issues, including impotence and erectile dysfunction, as well as inflammation, a response to injury or infection that can cause pain and swelling, and weight loss, a goal for many individuals seeking to improve their physical health. Furthermore, Eurycoma longifolia has been used to treat osteoporosis, a condition characterized by brittle bones, as well as cancer, a group of diseases that result from uncontrolled cell growth.
It has also been used to alleviate symptoms of arthritis, obesity, hypertension, insomnia, low testosterone, male infertility, sleep disorder, HIV, hypogonadism, and low libido.
What are the primary health benefits of Eurycoma longifolia?
Eurycoma longifolia increases testosterone levels in men by stimulating the production of luteinizing hormone, leading to improved muscle mass and bone density.
Reducing body fat is also a notable benefit, as Eurycoma longifolia has been shown to inhibit the activity of lipogenic enzymes, reducing fat storage and promoting weight loss. Improving mental clarity is attributed to the plant's ability to increase the production of acetylcholine, a neurotransmitter essential for cognitive function. Boosting immune system function is a result of Eurycoma longifolia's ability to stimulate the production of cytokines, which help to fight off infections and diseases.
Additionally, Eurycoma longifolia enhances physical performance by increasing muscle strength and endurance, reduces inflammation levels by inhibiting pro-inflammatory enzymes, lowers stress hormones by stimulating the production of serotonin, improves sleep quality by regulating the body's circadian rhythms, increases energy levels by stimulating the production of ATP, and supports the anti-aging process by reducing oxidative stress and promoting cellular renewal.
The following illustration give a summary of the primary health benefits of Eurycoma longifolia.
The list below provides more details on why Eurycoma longifolia offers the health benefits mentioned in the illustration above.
- Increases Testosterone: This plant is rich in bioactive compounds, particularly a quassinoid compound that has been shown to increase testosterone levels in men by inhibiting the production of sex hormone-binding globulin and enhancing the activity of 5-alpha-reductase, which converts testosterone into its more potent form.
- Reduces Body Fat: The active compounds in this plant have been found to increase the breakdown of fat cells and enhance the body's natural fat-burning processes, leading to a reduction in body fat and an improvement in body composition.
- Improves Mental Clarity: The bioactive compounds in this plant have been shown to have a stimulating effect on the brain, enhancing cognitive function, memory, and focus, and improving overall mental clarity and alertness.
- Boosts Immune System: This plant has been found to have immunomodulatory effects, enhancing the body's natural defense mechanisms and increasing the production of white blood cells, which helps to protect against infections and diseases.
- Enhances Physical Performance: The active compounds in this plant have been shown to increase muscle strength, endurance, and power, and enhance the body's ability to recover from exercise, making it a popular supplement among athletes and fitness enthusiasts.
- Reduces Inflammation Levels: This plant has been found to have anti-inflammatory effects, reducing the production of pro-inflammatory cytokines and enhancing the production of anti-inflammatory cytokines, which helps to reduce inflammation and improve overall health.
- Lowers Stress Hormones: The bioactive compounds in this plant have been shown to have a relaxing effect on the body, reducing the production of stress hormones such as cortisol and adrenaline, and promoting a sense of calm and well-being.
- Improves Sleep Quality: This plant has been found to have a sedative effect on the body, promoting relaxation and reducing stress and anxiety, which helps to improve sleep quality and duration.
- Increases Energy Levels: The active compounds in this plant have been shown to increase energy levels and reduce fatigue, making it a popular supplement among individuals who lead active lifestyles or who experience fatigue and lethargy.
- Supports Anti-Aging Process: This plant has been found to have antioxidant and anti-inflammatory effects, which helps to protect against oxidative stress and inflammation, and promote overall health and well-being, and may help to slow down the aging process.
The table that follows gives an overview of what are the primary health benefits of Eurycoma longifolia for each of the major body system.
| Body System | Health Benefits |
|---|---|
| Circulatory System | Improves Blood Flow, Regulates Blood Pressure, Enhances Circulation, Reduces Blood Clots, Improves Oxygenation, Boosts Heart Rate, Reduces Inflammation, Improves Vasodilation, Enhances Microcirculation, Stabilizes Blood Vessels |
| Digestive System | Alleviates Inflammation, Boosts Digestion, Cures Bloating, Eases Constipation, Fights Ulcers, Heals Diarrhea, Improves Absorption, Increases Motility, Reduces Nausea, Relieves Gas |
| Endocrine System | Stimulate Thyroid, Regulate Adrenaline, Balance Hormones, Reduce Insulin, Boost Metabolism, Stabilize Glucose, Improve Insulin Sensitivity, Enhance Endocrine Function, Regulate Cortisol Levels, Support Pancreatic Health |
| Integumentary System | Reduce Wrinkles, Prevent Dryness, Heal Cuts, Soothe Irritations, Repair Damage, Enhance Elasticity, Protect Barrier, Stimulate Regeneration, Accelerate Healing, Improve Texture |
| Lymphatic System | Stimulates Lymph Flow, Boosts Immune Defenses, Reduces Lymph Swelling, Enhances Lymph Filtration, Increases Lymph Production, Supports Detoxification Process, Improves Lymph Circulation, Reduces Lymph Inflammation, Activates Lymph Function, Maintains Lymph Balance |
| Musculoskeletal System | Reduce Joint Inflammation, Relieve Muscle Pain, Improve Bone Density, Increase Muscle Strength, Enhance Flexibility Quickly, Decrease Muscle Soreness, Relax Muscle Tension, Improve Mobility Freedom, Reduce Arthritis Symptoms, Prevent Muscle Degeneration |
| Nervous System | Reduces Stress, Improves Focus, Enhances Alertness, Regulates Mood, Boosts Energy, Supports Memory, Improves Concentration, Reduces Anxiety, Improves Cognitive, Enhances Motivation |
| Reproductive System | Boosts Libido, Increases Fertility, Enhances Sperm, Supports Hormones, Improves Ovulation, Stimulates Reproduction, Regulates Cycles, Increases Testosterone, Supports Pregnancy, Enhances Menopause |
| Respiratory System | Relieve Congestion, Reduce Inflammation, Improve Breathing, Calm Coughs, Prevent Wheezing, Eliminate Mucus, Strengthen Lungs, Heal Bronchitis, Fight Infections, Soothe Asthma |
| Urinary System | Prevents Kidney Damage, Reduces Urine Frequency, Cures Bladder Infections, Treats Prostate Issues, Protects Renal Function, Heals Kidney Stones, Prevents Urinary Tract, Cures Urinary Incontinence, Improves Urine Flow, Prevents Kidney Failure |
Circulatory System
Eurycoma longifolia improves blood flow by containing alkaloids and flavonoids that act as vasodilators, causing blood vessels to dilate and increase blood circulation.
This plant regulates blood pressure by exerting a hypotensive effect, reducing the resistance in blood vessels and lowering blood pressure. Eurycoma longifolia enhances circulation by increasing the production of nitric oxide, a potent vasodilator that relaxes smooth muscle cells and widens blood vessels. Additionally, it reduces blood clots by inhibiting platelet aggregation and coagulation, thereby preventing the formation of blood clots and thrombi.
Eurycoma longifolia also stabilizes blood vessels by preventing the degradation of collagen, a crucial component of blood vessel walls, thereby preventing damage and maintaining vascular health.
The medicinal benefits of Eurycoma longifolia on the circulatory system help relieving the health conditions listed below.
- Hypertension
- Varicose veins
- Anemia
- Cholesterol
- Blood clots
- Thrombosis
- Cardiomyopathy
- Atherosclerosis
Digestive System
Eurycoma longifolia alleviates inflammation due to its anti-inflammatory properties, reducing swelling and redness in the digestive tract.
Boosting digestion is also facilitated by the presence of enzymes in the plant, which aid in the breakdown of complex nutrients. The medicinal properties of Eurycoma longifolia, including antimicrobial and antioxidant properties, enable it to cure bloating by eliminating pathogens and toxins. Easing constipation is achieved through the increase in gut motility and the relaxation of smooth muscle, allowing for the proper movement of food through the digestive system.
The plant's ability to fight ulcers is attributed to its antimicrobial properties, which reduce the growth of Helicobacter pylori bacteria, a common cause of stomach ulcers, and heal diarrhea by regulating the balance of gut bacteria.
The medicinal benefits of Eurycoma longifolia on the digestive system help relieving the health conditions listed below.
- Constipation
- Diarrhea
- Gastroenteritis
- Nausea
- Ulcers
- Irritable bowel syndrome
- Hepatitis
Endocrine System
Eurycoma longifolia stimulate thyroid function by increasing the production of thyroid hormones, which regulate metabolism and energy levels.
It also regulate adrenaline levels by modulating the body's response to stress, thereby maintaining homeostasis. This plant balance hormones in the body, ensuring a delicate equilibrium between the endocrine system's various components. Additionally, Eurycoma longifolia reduce insulin resistance by enhancing insulin sensitivity and glucose uptake, which helps to stabilize glucose levels and boost metabolism.
Furthermore, it improve insulin sensitivity, regulate cortisol levels, enhance endocrine function, and support pancreatic health by reducing oxidative stress and inflammation in the pancreatic tissue.
The medicinal benefits of Eurycoma longifolia on the endocrine system help relieving the health conditions listed below.
- Low testosterone
- Fatigue
- Stress
- Anxiety
- Depression
- Hypothyroidism
- Sleep disorder
- Weight loss
- Osteoporosis
Integumentary System
Eurycoma longifolia reduce wrinkles by containing antioxidants that neutralize free radicals and prevent oxidative stress, thereby maintaining skin elasticity and firmness.
The antimicrobial properties of Eurycoma longifolia prevent dryness by inhibiting the growth of pathogenic microorganisms that cause skin dehydration. Eurycoma longifolia heal cuts by promoting wound closure and tissue repair due to its ability to stimulate collagen synthesis and promote cell proliferation. The anti-inflammatory properties of Eurycoma longifolia soothe irritations by reducing redness and swelling, and its regenerative properties repair damage by promoting the growth of new skin cells.
Eurycoma longifolia enhance elasticity by containing flavonoids that improve skin hydration and stimulate the production of glycosaminoglycans, which are essential for maintaining the integrity of the skin barrier, and protect barrier by maintaining the skin's natural barrier function, stimulate regeneration by promoting the growth of new skin cells, accelerate healing by reducing inflammation and promoting tissue repair, and improve texture by reducing fine lines and wrinkles.
The medicinal benefits of Eurycoma longifolia on the integumentary system help relieving the health conditions listed below.
- Acne
- Warts
- Psoriasis
- Alopecia
- Eczema
- Skin tags
- Age spots
- Fungal infections
Lymphatic System
Eurycoma longifolia stimulates lymph flow through its antioxidant properties, which help neutralize free radicals that can impede lymphatic circulation.
This stimulation also boosts immune defenses by increasing the production of white blood cells, which are essential for fighting infections. As a result of its anti-inflammatory properties, Eurycoma longifolia reduces lymph swelling and enhances lymph filtration, allowing the lymphatic system to efficiently remove waste and toxins. The plant's antimicrobial properties also increase lymph production, supporting the detoxification process and maintaining lymph balance.
Furthermore, Eurycoma longifolia improves lymph circulation, reduces lymph inflammation, and activates lymph function, ultimately supporting the body's natural detoxification processes.
The medicinal benefits of Eurycoma longifolia on the lymphatic system help relieving the health conditions listed below.
- Lymphedema
- Lymphatic cancer
- Edema
- Fibromyalgia
- Cachexia
- Aids-related wasting
Musculoskeletal System
Eurycoma longifolia reduce joint inflammation by exerting anti-inflammatory properties, which inhibit the production of pro-inflammatory enzymes and cytokines, thereby reducing swelling and pain in the musculoskeletal system.
Relieve muscle pain is also a benefit of Eurycoma longifolia, achieved through the analgesic and anxiolytic properties of its compounds, which help alleviate muscle spasms and anxiety-related pain. Improve bone density is another significant health benefit, attributed to the plant's antioxidant properties, which protect bone cells from oxidative damage and promote bone health. Increase muscle strength and enhance flexibility quickly are also associated with Eurycoma longifolia, due to its adaptogenic properties, which enable the body to adapt to physical stress and improve muscle function.
Eurycoma longifolia also decrease muscle soreness, relax muscle tension, improve mobility freedom, reduce arthritis symptoms, and prevent muscle degeneration, largely attributed to its anti-inflammatory, antioxidant, and anabolic properties.
The medicinal benefits of Eurycoma longifolia on the musculoskeletal system help relieving the health conditions listed below.
- Osteoarthritis
- Rheumatism
- Muscle soreness
- Inflammation
- Tendinitis
- Degenerative disc disease
- Fibromyalgia
- Sciatica
Nervous System
Eurycoma longifolia reduces stress by exerting adaptogenic properties, which enable the body to adapt to stressors.
It improves focus by stimulating the brain's neurotransmitters, such as dopamine and serotonin, through its neuromodulatory effects. Eurycoma longifolia enhances alertness due to its ability to increase the levels of certain neurotransmitters and hormones, like noradrenaline and adrenaline. The plant regulates mood by influencing the brain's neurotransmitter balance, specifically serotonin, which is involved in mood regulation.
Additionally, it boosts energy through its stimulatory properties, supports memory by increasing the growth of neurons, improves concentration by enhancing the brain's ability to focus, reduces anxiety by decreasing the levels of stress hormones, improves cognitive function through its neuroprotective effects, and enhances motivation by stimulating the brain's reward system.
The medicinal benefits of Eurycoma longifolia on the nervous system help relieving the health conditions listed below.
- Anxiety
- Depression
- Insomnia
- Fatigue
- Stress
- Burnout
Reproductive System
Eurycoma longifolia boosts libido by containing a compound called eurycomanone, which has been shown to increase testosterone levels in the body.
This increase in testosterone has been linked to enhanced sperm quality, which supports fertility and increases the chances of successful conception. The antioxidant properties of Eurycoma longifolia also support hormones, including estrogen, which is essential for ovulation and pregnancy. Additionally, Eurycoma longifolia stimulates reproduction by regulating cycles and promoting a healthy menstrual cycle, which can improve ovulation and increase the chances of conception.
Furthermore, Eurycoma longifolia enhances menopause by reducing symptoms such as hot flashes and night sweats, and supports pregnancy by ensuring the health and development of the fetus.
The medicinal benefits of Eurycoma longifolia on the reproductive system help relieving the health conditions listed below.
- Low sperm count
- Male infertility
- Erectile dysfunction
- Premature ejaculation
- Testosterone deficiency
Respiratory System
Eurycoma longifolia relieve congestion by reducing inflammation in the airways, allowing for smoother breathing.
Its antioxidant properties also improve breathing by neutralizing free radicals that can exacerbate respiratory issues. The antimicrobial properties of Eurycoma longifolia calm coughs by eliminating the underlying infection that causes the cough. Additionally, its anti-inflammatory properties prevent wheezing by reducing inflammation in the airways, while its expectorant properties eliminate mucus, making it easier to breathe.
Eurycoma longiforia soothe asthma by strengthening lungs and healing bronchitis, thereby reducing the frequency and severity of asthma attacks and allowing individuals to fight infections more effectively.
The medicinal benefits of Eurycoma longifolia on the respiratory system help relieving the health conditions listed below.
- Asthma
- Bronchitis
- Chronic cough
- Pneumonia
- Tuberculosis
Urinary System
Eurycoma longifolia prevents kidney damage by exerting its antioxidant properties, which neutralize free radicals and protect the kidneys from oxidative stress.
This plant also reduces urine frequency by regulating the renal system's function and improving the body's ability to filter waste products. Furthermore, its antimicrobial properties cure bladder infections by eliminating harmful bacteria that cause these infections. The plant's anti-inflammatory properties treat prostate issues by reducing swelling and promoting healthy tissue growth, while also protecting renal function by regulating the body's fluid balance.
Additionally, Eurycoma longifolia heals kidney stones by dissolving and removing them, prevents urinary tract infections by inhibiting the growth of harmful bacteria, cures urinary incontinence by strengthening the muscles that control urine flow, improves urine flow by relaxing the muscles in the urinary tract, and prevents kidney failure by supporting the kidneys' ability to filter waste products and regulate fluid balance.
The medicinal benefits of Eurycoma longifolia on the urinary system help relieving the health conditions listed below.
- Prostatitis
- Benign prostatic hyperplasia
- Kidney stones
- Urinary tract infections
- Enuresis
What are the dominant therapeutic properties of Eurycoma longifolia?
The therapeutic properties of Eurycoma longifolia are attributed to its antioxidant activity, which plays a crucial role in protecting cells from oxidative damage and promoting overall health.
This plant has been shown to exhibit antimicrobial properties, inhibiting the growth of various microorganisms and preventing infections. Eurycoma longifolia also possesses anti-inflammatory and analgesic properties, reducing inflammation and alleviating pain in individuals suffering from various conditions. The bioactive compounds found in Eurycoma longifolia, including flavonoids and saponins, contribute to its antioxidative properties, helping to neutralize free radicals and prevent cellular damage.
Its antidiabetic, neuroprotective, immunomodulatory, anticancer, and anti-androgenic properties further highlight the plant's potential in treating a range of diseases, including diabetes, neurodegenerative disorders, and certain types of cancer.
The following illustration give a summary of the dominant therapeutic properties of Eurycoma longifolia.
The list below provides more details on why Eurycoma longifolia has the therapeutic properties mentioned in the illustration above.
- Antioxidant: Eurycoma longifolia has been found to possess antioxidant properties, which are attributed to the presence of bioactive compounds such as flavonoids and phenolic acids. These compounds have been shown to scavenge free radicals and thereby protect cells from oxidative damage.
- Antimicrobial: Eurycoma longifolia has been demonstrated to exhibit antimicrobial activity against a range of microorganisms, including bacteria and fungi. This activity is thought to be mediated by the plant's bioactive compounds, which have been shown to inhibit the growth of microorganisms and disrupt their cell membranes.
- Anti-Inflammatory: Eurycoma longifolia has been found to possess anti-inflammatory properties, which are attributed to the presence of bioactive compounds such as flavonoids and phenolic acids. These compounds have been shown to inhibit the production of pro-inflammatory mediators and thereby reduce inflammation.
- Analgesic: Eurycoma longifolia has been found to exhibit analgesic activity, which is thought to be mediated by the plant's bioactive compounds. These compounds have been shown to inhibit the production of pain-related mediators and thereby reduce pain perception.
- Antioxidative: Eurycoma longifolia has been found to possess antioxidative properties, which are attributed to the presence of bioactive compounds such as flavonoids and phenolic acids. These compounds have been shown to scavenge free radicals and thereby protect cells from oxidative damage.
- Antidiabetic: Eurycoma longifolia has been found to exhibit antidiabetic activity, which is thought to be mediated by the plant's bioactive compounds. These compounds have been shown to inhibit the activity of enzymes involved in glucose metabolism and thereby reduce blood sugar levels.
- Neuroprotective: Eurycoma longifolia has been found to possess neuroprotective properties, which are attributed to the presence of bioactive compounds such as flavonoids and phenolic acids. These compounds have been shown to inhibit the production of neurotoxic mediators and thereby protect neurons from damage.
- Immunomodulatory: Eurycoma longifolia has been found to exhibit immunomodulatory activity, which is thought to be mediated by the plant's bioactive compounds. These compounds have been shown to modulate the activity of immune cells and thereby enhance immune function.
- Anticancer: Eurycoma longifolia has been found to exhibit anticancer activity, which is thought to be mediated by the plant's bioactive compounds. These compounds have been shown to inhibit the growth of cancer cells and induce apoptosis, which is the process of programmed cell death.
- Anti-Androgenic: Eurycoma longifolia has been found to exhibit anti-androgenic activity, which is thought to be mediated by the plant's bioactive compounds. These compounds have been shown to inhibit the activity of androgen receptors and thereby reduce the production of androgen hormones.
What are the major healing constituents of Eurycoma longifolia?
The healing constituents of Eurycoma longifolia are flavonoids which have anti-inflammatory properties and antioxidant activity, saponins with immunomodulatory and antifungal effects, phenolic acids exhibiting antimicrobial and anti-inflammatory actions, alkaloids such as eurycomanone and eurycomanol with potential anticancer and antioxidant activities, and terpenoids including eurycomanone and eurycolactone with anti-inflammatory and immunomodulatory properties, all contributing to its medicinal properties and uses.
Eurycoma longifolia's alkaloids have shown promise in inhibiting cancer cell growth and inducing apoptosis. Flavonoids and phenolic acids in Eurycoma longifolia have been reported to exhibit antioxidant activity, which can protect against oxidative stress and inflammation. Saponins in Eurycoma longifolia have been found to have immunomodulatory effects, enhancing the immune system's response to pathogens.
The combination of these constituents contributes to Eurycoma longifolia's traditional uses in treating various health conditions, including fatigue, low libido, and inflammation.
The following illustration give a summary of the major healing consitutents of Eurycoma longifolia.
The list below provides more details on what are the major healing constituents of Eurycoma longifolia and why they are important for health.
- Flavonoids: Flavonoids are antioxidant and anti-inflammatory constituents of Eurycoma longifolia, possessing radical scavenging and metal ion chelating properties.
- Saponins: Saponins are a class of compounds found in Eurycoma longifolia that exhibit anti-inflammatory, antimicrobial, and antioxidant properties.
- Phenolic acids: Phenolic acids from Eurycoma longifolia are a class of compounds with antioxidant, antimicrobial, and anti-inflammatory properties, including free radical scavenging and enzyme inhibition capabilities.
- Alkaloids: Alkaloids present in Eurycoma longifolia are reported to possess anti-inflammatory, antioxidant, and cytotoxic properties.
- Terpenoids: Terpenoids, a constituent of Eurycoma longifolia, possess anti-inflammatory, antioxidant and antimicrobial properties.
- Glycosides: Glycosides present in Eurycoma longifolia possess anti-inflammatory, antioxidant, and antimicrobial properties.
- Quassinoids: Quassinoids, found in Eurycoma longifolia, are a group of compounds that possess anti-inflammatory and antioxidant properties.
- Coumarins: Coumarins are a class of organic compounds found in Eurycoma longifolia, characterized by their ability to exhibit anti-inflammatory, antimicrobial, and antioxidant properties.
- Triterpenoids: Triterpenoids found in Eurycoma longifolia are known to exhibit antioxidant, anti-inflammatory, and antimicrobial properties.
- Sterols: Sterols are a group of lipid compounds found in Eurycoma longifolia with hypocholesterolemic, anti-inflammatory, and antioxidant properties.
The table that follows estimates the relative concentrations of the main medicinal constituents contained in Eurycoma longifolia and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.
| Constituent | Concentration | Properties |
|---|---|---|
| Flavonoids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Antiviral, Anticancer, Cardioprotective, Neuroprotective |
| Saponins | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Antipyretic, Antiviral |
| Phenolic acids | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Antiviral, Antibacterial, Analgesic |
| Alkaloids | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Analgesic, Antibacterial, Anticancer, Antiviral |
| Terpenoids | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Antifungal, Anticancer, Antiviral, Analgesic, Antispasmodic, Antiproliferative |
| Glycosides | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Immunomodulatory, Anticancer |
| Quassinoids | HIGH | Antimicrobial, Antioxidant, Anti-inflammatory, Immunomodulatory, Antiproliferative, Anticancer, Antidiabetic, Antihypertensive, Neuroprotective |
| Coumarins | LOW | Antioxidant, Anti-inflammatory, Antimicrobial, Anti-cancer, Antiviral, Anti-plaque |
| Triterpenoids | LOW | Antimicrobial, Antioxidant, Anti-inflammatory, Anticancer, Antiviral, Antibacterial, Cytotoxic, Immunomodulatory |
| Sterols | MEDIUM | Antimicrobial, Antioxidant, Anti-inflammatory, Antihyperlipidemic, Antioxidant, Cardioprotective, Immunomodulatory |
What are the most used parts of Eurycoma longifolia in medicine?
The most used parts of Eurycoma longifolia for medicinal purposes are the roots.
The roots of Eurycoma longifolia contain primary bioactive compounds such as flavonoids, alkaloids, and saponins, which contribute to their medicinal properties. The primary medicinal properties of the roots include antioxidant, anti-inflammatory, and immunomodulatory effects, as well as potential anticancer and antimicrobial activities. The bioactive compounds in the roots, particularly flavonoids and alkaloids, have been shown to scavenge free radicals and modulate the immune system, while saponins have been found to exhibit antimicrobial and anticancer properties.
These properties make the roots of Eurycoma longifolia a valuable resource for the development of traditional medicine and modern pharmaceuticals.
The following illustration give a summary of the most used parts of Eurycoma longifolia in medicine.
The list below provides more details on what are the most used parts of Eurycoma longifolia in medicine and why.
- Roots: The roots of this plant contain bioactive compounds such as eurycomanone, eurycolactone, and eurycomanoides, which exhibit anti-inflammatory, antioxidant, and immunomodulatory properties, providing primary health benefits including enhanced immune function, improved cardiovascular health, and potential anti-cancer effects.
The table that follows gives a more complete list of healing constituents found in each part of Eurycoma longifolia mentioned above.
| Part | Constituents |
|---|---|
| Roots | Bis(peroxy)olean-12-en-3-one, Catechins, Eurycomanone, Eurycomanol, Eurycomanid, Flavonoids, Lignans, Oleanane, Sesquiterpenes, Sterols |
What are the most common medicinal preparations of Eurycoma longifolia?
The most common herbal preparation of Eurycoma longifolia for medicinal purposes are tinctures, which are used to treat various conditions, including fatigue and low libido due to its high concentration of bioactive compounds.
Capsules are another form of preparation, providing a standardized dosage of the plant's extracts and are commonly used to enhance athletic performance and boost immune function. Eurycoma longifolia oil, obtained through a process of cold-pressing, is valued for its ability to reduce inflammation and promote wound healing. The leaves of the plant can be made into a tea, which is traditionally consumed to alleviate stress and anxiety, and improve sleep quality.
A salve is also prepared from the plant's extracts, providing topical relief from pain and inflammation.
The following illustration give a summary of the most common medicinal preparations of Eurycoma longifolia.
The list below provides more details on what are the most common medicinal preparations of Eurycoma longifolia and what are their main uses.
- Tincture: Tincture made from this plant is used to support testosterone production, enhance athletic performance, boost energy, and improve male fertility and libido.
- Capsule: Capsule made from this plant is used to treat fatigue, low libido, and erectile dysfunction, as well as to boost energy and endurance.
- Oil: Oil made from this plant is used to enhance male fertility, boost libido, and treat fatigue and erectile dysfunction.
- Tea: Tea made from this plant is used to treat fatigue, low libido and erectile dysfunction, and as an immune system stimulant.
- Salve: Salve made from this plant is used to treat wounds, reduce inflammation, and relieve pain, also used as an antifungal and antibacterial agent to aid in wound healing and prevent infection.
The table that follows shows what are the most used parts of Eurycoma longifolia for each medicinal preparation.
| Preparation | Parts |
|---|---|
| Tincture | Roots, Leaves |
| Capsule | Roots, Leaves |
| Oil | Roots |
| Tea | Roots, Leaves |
| Salve | Roots, Leaves |
Tincture
Eurycoma longifolia tincture is a herbal remedy widely used to treat various conditions, including impotence, hypogonadism, erectile dysfunction, fatigue, weight loss, anxiety, stress, depression, and insomnia.
It's one of the most common herbal preparations, often recommended by traditional practitioners. The tincture is commonly used to alleviate stress and anxiety, and many users report improved sleep quality, reduced fatigue, and enhanced mood. The preparation is made by soaking the roots and leaves of Eurycoma longifolia in a solvent, typically ethanol or glycerol, which is then strained and concentrated to create the final product.
The process of making Eurycoma longifolia tincture is moderately difficult, requiring a good understanding of herbal extraction techniques and equipment, such as a still or a solvent-based extraction system.
Below you find an image of Eurycoma longifolia tincture.
Below you find a 5-step quick procedure to make effective medicinal Eurycoma longifolia tincture.
- Harvest fresh Eurycoma longifolia roots and leaves, and clean them thoroughly.
- Dry the roots and leaves completely in a well-ventilated area or using a dehydrator.
- Combine the dried roots and leaves in a ratio of 2:1, and chop them into small pieces.
- Steep the chopped plant material in a solvent such as ethanol or glycerin for several weeks, shaking the mixture regularly.
- Strain the mixture through a cheesecloth or a coffee filter, and discard the solids to obtain the herbal tincture.
Capsule
Eurycoma longifolia capsule is used to treat various health issues including fatigue, low libido, impotence, anxiety, depression, stress and sleep disorders.
It's a very common herbal supplement widely used by people globally. One of its most common effects is increased energy levels and improved mental performance. The capsules are made from the roots and leaves of the Eurycoma longifolia plant, which is native to Southeast Asia.
The preparation process is relatively simple, involving drying and grinding of the plant material followed by encapsulation.
Below you find a 5-step quick procedure to make effective medicinal Eurycoma longifolia capsule.
- Harvest and clean the Eurycoma longifolia roots and leaves.
- Dry the roots and leaves in a well-ventilated area to remove excess moisture.
- Grind the dried roots and leaves into a fine powder using a grinder or mortar.
- Mix the powdered roots and leaves in a specific ratio to achieve the desired herbal blend.
- Fill a capsule shell with the herbal blend and seal it to create the Eurycoma longifolia herbal capsule.
Oil
Eurycoma longifolia oil is commonly used to treat erectile dysfunction, fatigue, depression, anxiety, sleep disorder, hair loss, skin conditions, and inflammation.
It is widely used in traditional medicine and is often incorporated into modern supplements due to its widespread adoption. One of the notable effects of Eurycoma longifolia oil is its ability to increase testosterone levels. The oil is typically made from the roots of the Eurycoma longifolia plant, which can be difficult to cultivate and harvest, contributing to its high price.
The process of extracting the oil from these roots can be labor-intensive, making Eurycoma longifolia oil a rare and valuable commodity.
Below you find an image of Eurycoma longifolia oil.
Below you find a 5-step quick procedure to make effective medicinal Eurycoma longifolia oil.
- Gather Eurycoma longifolia roots from a trusted supplier or harvest them sustainably from the wild.
- Clean and dry the Eurycoma longifolia roots to prevent contamination and spoilage.
- Chop the dried Eurycoma longifolia roots into small pieces to increase their surface area for infusion.
- Infuse the chopped Eurycoma longifolia roots in a carrier oil, such as coconut or olive oil, in a clean glass container for several weeks, shaking regularly.
- Strain the infused oil through a cheesecloth or coffee filter into a clean container, discarding the solids and storing the herbal oil in a cool, dark place.
Tea
Eurycoma longifolia tea is used to treat various conditions, including depression, hypogonadism, fatigue, erectile dysfunction, anxiety, insomnia, osteoporosis, and rheumatism.
It's a common herbal remedy, widely used in many cultures. One of its common effects is improved energy levels and reduced symptoms of fatigue. The tea is typically made from the roots and leaves of the Eurycoma longifolia plant.
Preparation is relatively straightforward, involving steeping the roots and leaves in hot water to create a tea that can be consumed as a natural remedy for the aforementioned conditions.
Below you find an image of Eurycoma longifolia tea.
Below you find a 5-step quick procedure to make effective medicinal Eurycoma longifolia tea.
- Harvest the roots and leaves of the Eurycoma longifolia plant, ensuring they are clean and free of contaminants.
- Rinse the roots and leaves thoroughly with water to remove any dirt or debris.
- Combine the cleaned roots and leaves in a saucepan, adding enough water to cover the plant material.
- Bring the mixture to a boil, then reduce the heat and simmer for an extended period to extract the active compounds.
- Strain the tea through a cheesecloth or fine-mesh sieve into a teapot or cup, discarding the solids.
Salve
Eurycoma longifolia salve is a herbal remedy used to treat various conditions including alopecia, arthritis, eczema, gout, and rheumatism.
It is a common preparation used in traditional medicine due to its widespread availability and usage. The salve has a common effect of reducing inflammation and pain in patients. The preparation is made from the roots and leaves of the Eurycoma longifolia plant.
Producing high-quality Eurycoma longifolia salve is a challenging process due to the complexity of extracting the bioactive compounds from the plant's roots and leaves, which requires expertise and precise techniques to ensure efficacy and safety.
Below you find an image of Eurycoma longifolia salve.
Below you find a 5-step quick procedure to make effective medicinal Eurycoma longifolia salve.
- Harvest and dry the roots and leaves of Eurycoma longifolia plants.
- Combine the dried roots and leaves in a mortar and pestle, and grind them into a fine powder.
- Mix the powdered Eurycoma longifolia with a carrier oil, such as coconut or olive oil, in a heat-resistant container.
- Heat the mixture over low heat, stirring occasionally, until the oil has fully infused with the Eurycoma longifolia properties.
- Strain the infused oil through a cheesecloth or a coffee filter into a clean container, discard the solids, and let the oil cool before transferring it to small containers for salve.
What are the possible side effects of Eurycoma longifolia if used improperly?
The possible side effects of improperly using Eurycoma longifolia are experiencing nausea, showing abdominal pain, and experiencing diarrhea, which are primarily gastrointestinal issues resulting from the plant's high concentration of compounds that can irritate the digestive system.
Developing dizziness and experiencing headache are also potential side effects, likely caused by the plant's stimulating properties affecting the central nervous system. Showing fatigue is another possible side effect, as the plant's active compounds may interfere with sleep patterns, leading to insomnia. Experiencing depression and developing anxiety are more severe side effects that can occur due to the plant's effect on neurotransmitters and brain chemistry.
Interacting with other medications is a critical concern, as Eurycoma longifolia may enhance or inhibit the effects of certain medications, potentially leading to adverse reactions.
The most common side effects Eurycoma longifolia gives people when used improperly are listed below, along with a brief explanation.
- Experiencing Nausea: Eurycoma longifolia causes gastrointestinal upset leading to nausea.
- Showing Abdominal Pain: Eurycoma longifolia causes abdominal pain in some individuals
- Experiencing Diarrhea: Eurycoma longifolia extracts cause gastrointestinal upset, leading to loose stools.
- Developing Dizziness: Eurycoma longifolia may cause dizziness in some individuals due to its high levels of ursolic acid and other bioactive compounds.
- Experiencing Headache: Eurycoma longifolia extracts cause vasoconstriction which can lead to increased intracranial pressure resulting in headache.
- Showing Fatigue: Eurycoma longifolia supplementation causes a decrease in physical activity and energy levels.
- Experiencing Insomnia: Consuming Eurycoma longifolia may interfere with sleep patterns due to its stimulatory effect on the central nervous system.
- Developing Anxiety: Eurycoma longifolia may induce anxiety in some individuals due to its stimulant properties and potential interactions with the central nervous system.
- Experiencing Depression: Low mood and emotional changes have been reported in individuals using Eurycoma longifolia extracts.
- Interacting With Other Medications: Eurycoma longifolia may interact with blood thinners and other medications, such as warfarin, due to its effect on cytochrome P450 and other enzyme systems.
What are the precautions to take before using Eurycoma longifolia medicinally?
The precautions to take before using Eurycoma longifolia medicinally are to consult a doctor before use, especially if you have any underlying health conditions.
Following the recommended dosage is crucial to avoid potential adverse effects, as exceeding the suggested amount can lead to increased risk of side effects. Additionally, monitor blood pressure, as Eurycoma longifolia may lower blood pressure and interact with medications. It is also essential to avoid use during pregnancy, and be cautious when using it with antidepressants, as it may exacerbate serotonin levels.
Furthermore, be aware of interactions with thyroid medications, monitor liver function, be aware of potential allergic reactions, and stop use if side effects occur, such as dizziness or stomach upset.
The most important precautions you must take before using Eurycoma longifolia for medicinal purposes are listed below, along with a brief explanation.
- Consult A Doctor Before Use: Interactions with medications or underlying health conditions may be present, requiring medical evaluation.
- Follow Recommended Dosage: Taking higher doses than recommended can lead to adverse effects including insomnia, anxiety, and gastrointestinal issues.
- Monitor Blood Pressure: Hypertension is a reported side effect of Eurycoma longifolia extract consumption.
- Be Aware Of Interactions With Medications: Eurycoma longifolia may interact with certain medications, including blood thinners, diabetes medications, and blood pressure medications.
- Avoid Use During Pregnancy: Eurycoma longifolia may stimulate uterine contractions, potentially inducing premature labor.
- Avoid Use With Antidepressants: Concomitant use with MAOIs and SSRIs increases the risk of serotonin syndrome.
- Be Cautious With Thyroid Medications: Eurycoma longifolia may interfere with the efficacy of thyroid hormone replacement therapy.
- Monitor Liver Function: Eurycoma longifolia may cause liver damage, so monitoring liver function is necessary
- Be Aware Of Allergic Reactions: Individuals with known allergies to plants in the family Guttiferae, which includes Eurycoma longifolia, may experience skin irritation, hives, or anaphylaxis upon exposure.
- Stop Use If Side Effects Occur: Discontinue use if dizziness, headache, nausea, or stomach upset occur.
Are there scientific studies that prove the medical effectiveness of Eurycoma longifolia?
Yes, there are several scientific studies that prove the medicianl effectiveness of Eurycoma longifolia. Here are some studies that are worthy of notice.
According to a study published by the "Japanese journal of pharmacology", Eurycoma longifolia has been found to exhibit anxiolytic effects in mice, reducing immobility and anxiety-like behaviors in both open-field and elevated plus-maze tests. The extract of Eurycoma longifolia also increased exploratory behaviors, such as the number of squares crossed and entries into open arms. Furthermore, it was observed to decrease fighting episodes, indicating a potential therapeutic use of Eurycoma longifolia in anxiety therapy.
In another study published by "Medicina (Kaunas, Lithuania)", Eurycoma longifolia has been found to significantly increase total testosterone levels in men, including both healthy volunteers and those with hypogonadism. The study, which conducted a systematic review and meta-analysis of randomized clinical trials, revealed a significant improvement in testosterone levels after Eurycoma longifolia treatment. This may represent a safe and promising therapeutic option for enhancing testosterone production, particularly in hypogonadal men.
A different research published by "Archives of pharmacal research", Eurycoma longifolia has been found to possess pro-androgenic properties, significantly increasing the weight of the levator ani muscle in both uncastrated and testosterone-stimulated castrated intact male rats. This effect, observed in rats dosed with the plant's fractions, suggests that Eurycoma longifolia may enhance male virility and sexual prowess. Specifically, the study found that 800 mg/kg of the plant's fractions significantly increased the levator ani muscle weight, further supporting its traditional use as an aphrodisiac.
