boneset
Eupatorium perfoliatum · Accepted scientific name
Scientific literature: Very Extensive (539 studies) · ★★★★★
Boneset, scientifically known as Eupatorium perfoliatum, is a perennial herb native to North America, renowned for its historical medicinal uses. Traditionally employed to treat fevers, influenza, and various inflammatory conditions, this plant is easily identified by its distinctive leaves that appear to clasp directly onto the stem.
Names
Common Names
- boneset
- perfoliate thoroughwort
- thoroughwax
- thoroughwort
Regional and Traditional Names
Spanish:
- Eupatorium truncatum
- Eupatorium salviifolium
- Eupatorium chapmanii
- Uncasia truncata
- Uncasia perfoliata
- Eupatorium connatum
- Eupatorium virginicum
- Cunigunda perfoliata
- Eupatorium glandulosum
German:
- Durchwachsener Wasserdost
- Durchwachsener Wasserhanf
- Wasserdostenkraut
- Indianerkraut
- Amerikanischer Wasserdost
- Knochenheil
- Eupatorium connatum
- Wechselfieberkraut
- Eupatorium virginicum
- Eupatorium glandulosum
- durchwachsener Wasserdost
French:
- eupatoire perfoliée
- herbe à souder
Scientific Names
Accepted name
Eupatorium perfoliatumSynonyms
- Cunigunda perfoliata
- Uncasia perfoliata
- Eupatorium perfoliatum var. colpophilum
- Eupatorium perfoliatum f. purpureum
- Eupatorium polyneuron
- Eupatorium chapmanii
- Eupatorium perfoliatum f. trifolium
- Eupatorium perfoliatum f. laciniatum
- Eupatorium serotinum var. polyneuron
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it is organized under the order Asterales and the family Asteraceae. Finally, its specific taxonomic identification is placed within the genus Eupatorium.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Asterales | WCVP |
| Family | Asteraceae | WCVP |
| Genus | Eupatorium | WCVP |
Distribution
This plant exhibits a wide geographical distribution across several provinces in Canada. In Western Canada, its presence is noted within the province of Manitoba. Moving to the eastern part of the country, it can be found in Ontario. The species also extends into the Atlantic provinces, specifically occupying New Brunswick and Nova Scotia. Additionally, its range includes the island province of Prince Edward Island.
| Region | Area | Source |
|---|---|---|
| Western Canada | Manitoba | WCVP |
| Eastern Canada | New Brunswick | WCVP |
| Eastern Canada | Nova Scotia | WCVP |
| Eastern Canada | Ontario | WCVP |
| Eastern Canada | Prince Edward I. | WCVP |
| Eastern Canada | Québec | WCVP |
| North-Central U.S.A. | Illinois | WCVP |
| North-Central U.S.A. | Iowa | WCVP |
| North-Central U.S.A. | Kansas | WCVP |
| North-Central U.S.A. | Minnesota | WCVP |
Chemicals
Eupatorium perfoliatum has 48 reported phytochemicals identified across 0 scientific publications and several other databases. The most consistently reported chemicals include EUPAFOLIN, quercetin, Alanine Aminotransferase, Ash, Astragalin.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| EUPAFOLIN | 2 supporting sources | ★☆☆☆☆ |
| quercetin | 2 supporting sources | ★☆☆☆☆ |
| Alanine Aminotransferase | 1 supporting sources | ★☆☆☆☆ |
| Ash | 1 supporting sources | ★☆☆☆☆ |
| Astragalin | 1 supporting sources | ★☆☆☆☆ |
| CALCIUM | 1 supporting sources | ★☆☆☆☆ |
| CHROMIUM | 1 supporting sources | ★☆☆☆☆ |
| COBALT | 1 supporting sources | ★☆☆☆☆ |
| Dendroidinic acid | 1 supporting sources | ★☆☆☆☆ |
| Eucannabinolide | 1 supporting sources | ★☆☆☆☆ |
EUPAFOLIN
- Dr. Duke
- Journal of ethnopharmacology
quercetin
- Dr. Duke
- Journal of ethnopharmacology
Alanine Aminotransferase
- Archives of pathology & laboratory medicine
Ash
- Dr. Duke
Astragalin
- Dr. Duke
CALCIUM
- Dr. Duke
CHROMIUM
- Dr. Duke
COBALT
- Dr. Duke
Dendroidinic acid
- Dr. Duke
Eucannabinolide
- Dr. Duke
Activities
Eupatorium perfoliatum has 483 reported activities identified across 0 scientific publications and several other databases. The most consistently reported activities include 11B-HSD-Inhibitor, 5-HT-Inhibitor, 5-Lipoxygenase-Inhibitor, ACE-Inhibitor, AP-1-Inhibitor.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| 11B-HSD-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| 5-HT-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| 5-Lipoxygenase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| ACE-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| AP-1-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| ATPase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Acidulant | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Alcohol-Dehydrogenase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Aldehyde-Oxidase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Aldose-Reductase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Eupatorium perfoliatum has 4 reported medicinal uses identified across 0 scientific publications and several other databases. The most consistently reported uses include fever, infections, influenza A virus, scabies.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| fever | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| infections | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| influenza A virus | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| scabies | Dermatologic therapy (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| alcoholic tinctures | Phytochemical analysis : PCA (and other 1 sources) | ★☆☆☆☆ |
| boneset | Phytochemical analysis : PCA (and other 1 sources) | ★☆☆☆☆ |
| decoctions | Phytochemical analysis : PCA (and other 1 sources) | ★☆☆☆☆ |
| extract | Arzneimittel-Forschung (and other 1 sources) | ★☆☆☆☆ |
| hot water infusions | Phytochemical analysis : PCA (and other 1 sources) | ★☆☆☆☆ |
| hydroalcoholic extracts | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| spagyric extract | Journal of clinical laboratory analysis (and other 1 sources) | ★☆☆☆☆ |