Eupatorium lindleyanum
Eupatorium lindleyanum · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Eupatorium lindleyanum is a versatile medicinal plant that contains various bioactive components such as flavonoids, astragalin, jaceosidin, and eupalinolide B. Utilizing the whole plant or specific preparations, researchers have explored its significant cytotoxic activities. The various parts of the plant, including the flower, leaf, root, and stem, contribute to its diverse therapeutic potential. It is particularly noted for its application in managing health conditions like bronchitis, cough, tonsillitis, and periodontitis. Through these chemical properties, this species offers promising avenues for pharmacological development.
- Synonyms
- Not available
- Common names
- Not available
- Family
- Asteraceae
- Distribution
- Not available
- Plant Parts
- Flower · Leaf
Classification
Taxonomy
Eupatorium lindleyanum is a fascinating botanical specimen that belongs to the vast kingdom Plantae. Within this biological kingdom, it is specifically classified under the class Equisetopsida. This plant is a member of the order Asterales, showcasing its evolutionary connections to other flowering species. Further refinement of its identity places it within the diverse family Asteraceae. Ultimately, its scientific classification is anchored by its placement in the genus Eupatorium.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Asterales |
| Family | Asteraceae |
| Genus | Eupatorium |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Eupatorium lindleyanum is a plant species with a widespread presence across the Asia-Temperate region. Its distribution is particularly notable throughout various sectors of China, ranging from the North-Central areas to the Southeast. The species also thrives in the South-Central provinces, demonstrating significant adaptability to different climates. Furthermore, its range extends to the tropical island of Hainan and the northern reaches of Inner Mongolia. This diverse geographic footprint highlights the plant's ability to establish itself across vastly different Chinese landscapes.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Eupatorium lindleyanum is a self-supporting herb that maintains a sturdy structure within its natural habitat. This plant typically exhibits a versatile growth habit, with heights generally ranging from a minimum of 0.3 m to a maximum of 1.5 m. Depending on its environmental conditions, it frequently settles into a more consistent height range between 0.9 m and its peak. Such structural flexibility allows the species to adapt effectively to various landscapes. Overall, its physical proportions define its unique presence among other herbaceous flora.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Eupatorium lindleyanum has been identified as a significant source of bioactive sesquiterpene lactones. Researchers successfully isolated ten new guaiane-type compounds, specifically named eupalinilides A-J, from the whole plant. Among these isolated substances, several were rigorously tested for their biological impact on various cancer models. The study revealed that eupalinilides B and E demonstrate potent cytotoxic activity against P-388 and A-549 tumor cell lines. These findings highlight the plant's potential as a valuable resource in the development of new anticancer agents.
Compounds
Eupatorium lindleyanum is a plant species that possesses a diverse array of complex chemical constituents. Research into its whole plant composition has identified several significant sesquiterpene lactones, including eupachinilide C, eupachinilide E, and eupachifolin D. Additionally, the compound 2alpha-hydroxyeupatolide has been successfully isolated from the specimen. Beyond these lactones, studies on the aerial parts of the plant have also revealed the presence of the flavonoid astragalin. Together, these various chemical relationships highlight the rich phytochemical profile of this botanical species.
Conditions
Eupatorium lindleyanum contains sesquiterpene lactones that demonstrate potent cytotoxicity against both P-388 and A-549 tumor cell lines. The plant's component, eupalinolide B, has been shown to ameliorate alveolar bone resorption by targeting the UBE2D3 enzyme to suppress inflammation. In traditional medicinal practice, the herb is recognized for its asthma-calming properties and its ability to reduce phlegm. It is also widely utilized as a treatment for bronchitis and persistent coughs. These diverse therapeutic effects are largely attributed to the high concentrations of active compounds found within its flowers and leaves.
Preparations
Eupatorium lindleyanum serves as the biological source from which the sesquiterpenoid natural product Eupalinolide B is extracted. This specific compound, Eupalinolide B, has demonstrated significant potential in inhibiting periodontitis by targeting the ubiquitin conjugating enzyme UBE2D3. Furthermore, the research indicates that various chemical constituents, including several new guaiane type sesquiterpene lactones, are isolated from the whole plant of Eupatorium lindleyanum. The isolation of these bioactive compounds like eupalinilides A-J was achieved by processing the whole plant material. Consequently, both the whole plant and its specific derivative, Eupalinolide B, are central to the study of its medicinal properties.
Parts used
Eupatorium lindleyanum is a medicinal plant from the Asteraceae family that is highly valued for its diverse bioactive compounds. Recent research has utilized integrative metabolomic and transcriptomic approaches to investigate the flavonoid biosynthesis pathway within this species. To understand these complex metabolic processes, scientists analyzed samples taken from the plant's roots, stems, leaves, and flowers. This tissue-specific analysis revealed significant variations in both differentially expressed genes and accumulated metabolites across the different parts. Ultimately, these findings provide a foundation for developing new cultivars with enhanced medicinal value through improved flavonoid content.