Erythroxylum pervillei
Erythroxylum pervillei · Accepted scientific name
Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆
Erythroxylum pervillei is a distinctive botanical species of significant scientific interest due to its unique chemical properties. Researchers have focused their attention on the plant's root and stem components to uncover potential bioactive compounds. Recent studies highlight the plant's relevance in the ongoing global struggle against multidrug resistance in various pathogens. By investigating these specific plant parts, scientists hope to identify novel therapeutic agents that can bypass existing medicinal defenses. Understanding the metabolic profile of this species remains a critical step in developing next-generation treatments.
- Synonyms
- Erythroxylum Pervillei F. Majusculum · Erythroxylum Pervillei Var. Suborbiculare
- Common names
- Not available
- Family
- Erythroxylaceae
- Distribution
- Asia-Temperate
- Plant Parts
- Root · Stem
Classification
Synonyms
Erythroxylum pervillei is a botanical species that is associated with several recognized taxonomic synonyms. Among these variations is the form known as Erythroxylum pervillei f. majusculum. Additionally, the plant is linked to the variety Erythroxylum pervillei var. suborbiculare. These designations help researchers categorize the different morphological forms found within the species. Understanding these relationships is essential for maintaining accurate botanical records and classification.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Erythroxylum pervillei is a fascinating member of the kingdom Plantae. Within this vast biological realm, the species is classified under the class Equisetopsida. It belongs to the diverse order Malpighiales, showcasing its evolutionary connections to related botanical groups. Further narrowing its identity, the plant is a primary representative of the genus Erythroxylum. Finally, it resides within the specialized family Erythroxylaceae, completing its unique taxonomic profile.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Malpighiales |
| Family | Erythroxylaceae |
| Genus | Erythroxylum |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Erythroxylum pervillei is a specialized plant species defined by its unique geographical footprint. Its native range spans across much of the African continent, showcasing a remarkable adaptability to various terrains. Beyond the mainland, the species extends its reach into the diverse ecosystems of the Western Indian Ocean. Madagascar also serves as a critical habitat for this plant, contributing to its overall biodiversity. Together, these regions form a distinct corridor that supports the survival and distribution of the species.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Erythroxylum pervillei typically grows in the form of a shrub.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Compounds
Conditions
Erythroxylum pervillei contains tropane alkaloid aromatic esters that demonstrate significant activity against various human cancer cell lines. These compounds effectively treat multidrug-resistance by acting as potent modulators of P-glycoprotein. Specifically, the plant's extracts show efficacy in treating vinblastine-resistant oral epidermoid carcinoma (KB-V1) cells. Research also indicates that these substances can treat human ovarian adenocarcinoma (SKVLB) cells when evaluated alongside adriamycin. Furthermore, the synergistic potential of these alkaloids has been confirmed through studies involving the NCI tumor panel.
Preparations
Parts used
Erythroxylum pervillei serves as a significant source of bioactive tropane alkaloid aromatic esters. Researchers have successfully isolated nine distinct compounds from the roots of this plant, which demonstrate a potential to reverse multidrug resistance in certain cancer cell lines. Furthermore, investigations into the stem bark of the species have revealed additional minor constituents, such as pervilleines G and H. These studies highlight how different parts of the plant, specifically the roots and the stems, contain unique chemical profiles. Ultimately, the structural characterization of these alkaloids underscores the botanical importance of Erythroxylum pervillei in pharmacological research.